Download or read book Discovering the Dominant Complete Series written by Lucia Jordan and published by Wild Hearts Romance. This book was released on 2021-11-03 with total page 85 pages. Available in PDF, EPUB and Kindle. Book excerpt: Seven years ago, Michael Hallmore became the first guy to ever ask Katie out, though he also became the first guy to ever stand her up, leaving her humiliated. These days, Michael is known as one of most eligible bachelors in the world, and the multibillionaire tycoon has a history of being cold, difficult to please, and unreasonably controlling. Katie has always kept a special rotten place in her heart for this man, yet now she’s expected to not only see him, but to talk to him like he’s her boss. She knows it’s a death sentence. Michael knows something isn’t right the moment he lays eyes on the young interior designer entering his office. There isn’t a fleck of apprehension or submission in the eyes of this beauty, with her short, dark hair and gorgeous legs. But will Michael be able to put his dominant nature aside while working with Katie? Will Katie’s resolve only feed his burning desire to have her bound to his bed, submitting to him? Will Katie still feel the same uncontrollable desire for him she felt when they first met? And what will happen when Katie learns the truth behind this man she can’t help but be devastatingly drawn to?
Download or read book Discovering Dominance written by Clover Cox and published by Clover Cox. This book was released on 2018-10-11 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jean is not the kind of woman to do what a man tells her without question. When Becky recommends a how-to guide on the female-led relationship lifestyle, Jean takes the book and runs with it. Jean Avila's husband loses his job, which forces Jean to provide for the house. Jean doesn't mind bringing home the bacon, but her husband, Joseph Watts, leaves her to do all the chores too. Joseph loves his black Goddess, though, and he'll do anything to keep her. She’ll test his limits though when they enter the alluring world of femdom. Discovering Dominance is a femdom romance story involving a married couple, and there just might be a little cuckholding too.
Download or read book Ant Ecology written by Lori Lach and published by Oxford University Press. This book was released on 2010 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The incredible global diversity of ants, and their important ecological roles, mean that we cannot ignore the significance of ants in ecological systems. Ant Ecology takes the reader on a journey of discovery from the beginnings of ants many hundreds of thousands of years ago, through to the makings of present day distributions.
Download or read book Protein and Peptide Mass Spectrometry in Drug Discovery written by Michael L. Gross and published by John Wiley & Sons. This book was released on 2011-09-26 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book that highlights mass spectrometry and its application in characterizing proteins and peptides in drug discovery An instrumental analytical method for quantifying the mass and characterization of various samples from small molecules to large proteins, mass spectrometry (MS) has become one of the most widely used techniques for studying proteins and peptides over the last decade. Bringing together the work of experts in academia and industry, Protein and Peptide Mass Spectrometry in Drug Discovery highlights current analytical approaches, industry practices, and modern strategies for the characterization of both peptides and proteins in drug discovery. Illustrating the critical role MS technology plays in characterizing target proteins and protein products, the methods used, ion mobility, and the use of microwave radiation to speed proteolysis, the book also covers important emerging applications for neuroproteomics and antigenic peptides. Placing an emphasis on the pharmaceutical industry, the book stresses practice and applications, presenting real-world examples covering the most recent advances in mass spectrometry, and providing an invaluable resource for pharmaceutical scientists in industry and academia, analytical and bioanalytical chemists, and researchers in protein science and proteomics.
Download or read book Biochips as Pathways to Drug Discovery written by Andrew Carmen and published by CRC Press. This book was released on 2006-10-19 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the fiercely competitive pharmaceutical marketplace, your organization cannot afford to spend excess dollars developing drugs that will fail to get FDA approval or have profoundly poor characteristics. Biochips as Pathways to Drug Discovery takes a comprehensive look at how the industry faces these challenges, using new technologies such as bioc
Download or read book Machine Learning and Knowledge Discovery in Databases Part II written by Dimitrios Gunopulos and published by Springer Science & Business Media. This book was released on 2011-09-06 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: This three-volume set LNAI 6911, LNAI 6912, and LNAI 6913 constitutes the refereed proceedings of the European conference on Machine Learning and Knowledge Discovery in Databases: ECML PKDD 2011, held in Athens, Greece, in September 2011. The 121 revised full papers presented together with 10 invited talks and 11 demos in the three volumes, were carefully reviewed and selected from about 600 paper submissions. The papers address all areas related to machine learning and knowledge discovery in databases as well as other innovative application domains such as supervised and unsupervised learning with some innovative contributions in fundamental issues; dimensionality reduction, distance and similarity learning, model learning and matrix/tensor analysis; graph mining, graphical models, hidden markov models, kernel methods, active and ensemble learning, semi-supervised and transductive learning, mining sparse representations, model learning, inductive logic programming, and statistical learning. a significant part of the papers covers novel and timely applications of data mining and machine learning in industrial domains.
Download or read book E Discovery Tools and Applications in Modern Libraries written by de Smet, Egbert and published by IGI Global. This book was released on 2016-07-13 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technology has revolutionized the ways in which libraries store, share, and access information. As digital resources and tools continue to advance, so too do the opportunities for libraries to become more efficient and house more information. E-Discovery Tools and Applications in Modern Libraries presents critical research on the digitization of data and how this shift has impacted knowledge discovery, storage, and retrieval. This publication explores several emerging trends and concepts essential to electronic discovery, such as library portals, responsive websites, and federated search technology. The timely research presented within this publication is designed for use by librarians, graduate-level students, technology developers, and researchers in the field of library and information science.
Download or read book A Discovery of Witches written by Deborah Harkness and published by Penguin. This book was released on 2011-02-08 with total page 593 pages. Available in PDF, EPUB and Kindle. Book excerpt: Book one of the New York Times bestselling All Souls series, from the author of The Black Bird Oracle. “A wonderfully imaginative grown-up fantasy with all the magic of Harry Potter and Twilight” (People). Look for the hit series “A Discovery of Witches,” now streaming on AMC+, Sundance Now, and Shudder! Deborah Harkness’s sparkling debut, A Discovery of Witches, has brought her into the spotlight and galvanized fans around the world. In this tale of passion and obsession, Diana Bishop, a young scholar and a descendant of witches, discovers a long-lost and enchanted alchemical manuscript, Ashmole 782, deep in Oxford's Bodleian Library. Its reappearance summons a fantastical underworld, which she navigates with her leading man, vampire geneticist Matthew Clairmont. Harkness has created a universe to rival those of Anne Rice, Diana Gabaldon, and Elizabeth Kostova, and she adds a scholar's depth to this riveting tale of magic and suspense. The story continues in book two, Shadow of Night, book three, The Book of Life, and the fourth in the series, Time’s Convert.
Download or read book Advances in Knowledge Discovery and Data Mining Part II written by Mohammed J. Zaki and published by Springer. This book was released on 2010-05-29 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 14th Pacific-Asia Conference, PAKDD 2010, held in Hyderabad, India, in June 2010.
Download or read book Who Discovered What When written by Arron Wood and published by New Holland Publishers (AU). This book was released on 2005 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: You need no specialised knowledge of science to find interest and value in this unique book. The author's grasp of all spheres of science is so firm that he can explain complex ideas with startling clarity. Each chapter covers a half-century, and the pithy 200-300 word stories are arranged chronologically.
Download or read book Targeting Ion Channels for Drug Discovery Emerging Challenges for High Throughput Screening Technologies written by Ciria Hernandez and published by Frontiers Media SA. This book was released on 2024-06-07 with total page 153 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ligand and voltage-gated ion channels are highly regulated protein molecules that cross the cell membrane allowing ion flow from one side of the membrane to the other. They are ubiquitously expressed in human tissues and consist of one of the largest and best understood functional groups of proteins, with more than 400 members spanning nearly 1% of the human genome. They are involved in a variety of fundamental physiological processes, and their malfunction causes numerous diseases. In terms of the challenges faced in the effort to discover specific drugs in ancient and emerging diseases, ion channels are the third-largest class of target proteins after G-protein-coupled receptors (GPCRs) and kinases. 15% of small molecule drug targets have been reported to be voltage- or ligand-gated ion channels, resulting in approximately 150 new drug candidates in preclinical and clinical studies. Of the ion channel targeting drugs found on the market, these were identified more than a decade ago, and many of the current studies are at various stages of scientific approval. Overcoming these challenges has led the field of ion channel drug discovery to transform over the past 15 years through major advancements in genetic target detection, validation, structure-based drug design, and drug modeling of cell-based diseases.
Download or read book Artificial Intelligence and Visualization Advancing Visual Knowledge Discovery written by Boris Kovalerchuk and published by Springer Nature. This book was released on 2024 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zusammenfassung: This book continues a series of Springer publications devoted to the emerging field of Integrated Artificial Intelligence and Machine Learning with Visual Knowledge Discovery and Visual Analytics that combine advances in both fields. Artificial Intelligence and Machine Learning face long-standing challenges of explainability and interpretability that underpin trust. Such attributes are fundamental to both decision-making and knowledge discovery. Models are approximations and, at best, interpretations of reality that are transposed to algorithmic form. A visual explanation paradigm is critically important to address such challenges, as current studies demonstrate in salience analysis in deep learning for images and texts. Visualization means are generally effective for discovering and explaining high-dimensional patterns in all high-dimensional data, while preserving data properties and relations in visualizations is challenging. Recent developments, such as in General Line Coordinates, open new opportunities to address such challenges. This book contains extended papers presented in 2021 and 2022 at the International Conference on Information Visualization (IV) on AI and Visual Analytics, with 18 chapters from international collaborators. The book builds on the previous volume, published in 2022 in the Studies in Computational Intelligence. The current book focuses on the following themes: knowledge discovery with lossless visualizations, AI/ML through visual knowledge discovery with visual analytics case studies application, and visual knowledge discovery in text mining and natural language processing. The intended audience for this collection includes but is not limited to developers of emerging AI/machine learning and visualization applications, scientists, practitioners, and research students. It has multiple examples of the current integration of AI/machine learning and visualization for visual knowledge discovery, visual analytics, and text and natural language processing. The book provides case examples for future directions in this domain. New researchers find inspiration to join the profession of the field of AI/machine learning through a visualization lens.
Download or read book Accelerating Scientific Discovery Through Computation and Visualization written by and published by DIANE Publishing. This book was released on with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Scientists An Epic of Discovery written by Andrew Robinson and published by Thames & Hudson. This book was released on 2023-04-25 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: An intriguing and illuminating read for science buffs, those fascinated by the lives and minds of great men and women, and anyone curious about how we came to understand the physical world The ideas, experiments, and inventions of great scientists have revolutionized our understanding of the world around us. Theories, discoveries, and technologies—from relativity, the genetic code, and the periodic table to synthetic drugs, nuclear weapons, and brain scans—have transformed the physical world and our lives. Copernicus, Crick, Watson, Galileo, Marie Curie: these are some of the forty pioneers behind modern science whose stories are explored here. The scientists come from around the globe and represent multiple nationalities—American, English, German, French, Dutch, Czech, Indian, Japanese, and more. Often unorthodox thinkers, they frequently had to struggle against hostile contemporaries to gain recognition for their ideas and discoveries. All the major scientific disciplines are covered, including astronomy, biology, biochemistry, chemistry, computing, ecology, geology, medicine, neurology, physics, and psychology, as well as mathematics.
Download or read book The Discovery of Islands written by J. G. A. Pocock and published by Cambridge University Press. This book was released on 2005-09-08 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Discovery of Islands consists of a series of linked essays in British history, written by one of the world's leading historians of political thought and published over the past three decades. Its purpose is to present British history as that of several nations interacting with - and sometimes seceding from - an imperial state. The commentary presents this history as that of an archipelago, expanding across oceans to the Antipodes. Both New Zealand history and the author's New Zealand heritage inform this vision, presenting British history as oceanic and global, complementing (and occasionally criticising) the presentation of that history as European. Professor Pocock's interpretation of British history has been hugely influential in recent years, making The Discovery of Islands a resource of immense value for historians of Britain and the world.
Download or read book Epitope Recognition Since Landsteiner s Discovery written by M. Eibl and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Karl Landsteiner is best known for his discovery of the human blood goups. The revolutionary discoveries of this brilliant scientist in other fields have not received the recognition they deserve. His demonstration that poliomyelitis is transmissable showed the way of modern virology. His studies opening the field for epitope recognition, which he himself considered his main achievement, laid the foundation for research ongoing in our days. This book with its outstanding contributors is but a small tribute to this visionary scientist.
Download or read book Mastering Project Discovery written by Elliot Bendoly and published by Taylor & Francis. This book was released on 2024-04-11 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introducing a comprehensive approach to invigorate project leadership, this book provides a framework – the OUtCoMES Cycle – for developing, managing, advancing, and optimizing engineering and analytics projects. All too often, issues of moral hazard and completion bias prevent engineering and analytics managers and team leaders from asking the critical question 'What’s the problem?', before committing time, energy, and resources to solve it. This book draws attention to the definition, structuring, option consideration and ultimately the addressing of the right problems, exploring the OUtCoMES Cycle framework that facilitates and energizes systematic thinking, knowledge sharing, and on-the-fly adjustment with an explicit focus on the maximization of value and ROI. Each chapter includes discussions and lessons in analytical and engineering problem identification, problem structuring, iterative problem development (mental and computational) and problem resolution, at least three embedded real-world case studies, and a closing 'Practitioner’s Recap' to contextualize key chapter takeaways. Written by a team of established academic scholars and practicing analysts and engineers, this is an accessible and culture-shifting action guide for instructors interested in training the next generation of project and analytics leaders, students of analytics and engineering, as well as practicing project leaders and principals.
