Download or read book Diagnostic Pathology and Molecular Genetics of the Thyroid written by Yuri E. Nikiforov and published by Lippincott Williams & Wilkins. This book was released on 2012-04-20 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Pathology and Molecular Genetics of the Thyroid, Second Edition, offers a comprehensive overview of the diagnostic surgical pathology, cytopathology, immunohistochemistry and molecular genetics of the thyroid diseases, including neoplastic and non-neoplastic conditions. The book provides a detailed description of the surgical pathology of thyroid diseases side by side with major advances in immunohistochemistry and molecular genetics that can be used in evaluating thyroid tumors and non-neoplastic diseases.
Download or read book Diagnostic Pathology And Molecular Genetics Of The Thyroid written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diagnostic Pathology and Molecular Genetics of the Thyroid written by Yuri E. Nikiforov and published by LWW. This book was released on 2018-12-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Offering a comprehensive overview of the diagnostic surgical pathology, cytopathology, immunohistochemistry and molecular genetics of the thyroid diseases, this updated reference now incorporates recent, groundbreaking studies and major changes in the field"--
Download or read book Diagnostic Pathology and Molecular Genetics of the Thyroid written by Yuri Nikiforov and published by . This book was released on 2020 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Offering a comprehensive overview of the diagnostic surgical pathology, cytopathology, immunohistochemistry and molecular genetics of the thyroid diseases, this updated reference now incorporates recent, groundbreaking studies and major changes in the field"--
Download or read book Diagnostic Pathology and Molecular Genetics of the Thyroid written by Yuri E. Nikiforov and published by Lippincott Williams & Wilkins. This book was released on 2015-04-24 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Diagnostic Pathology and Molecular Genetics of the Thyroid, " Second Edition, offers a comprehensive overview of the diagnostic surgical pathology, cytopathology, immunohistochemistry and molecular genetics of the thyroid diseases, including neoplastic and non-neoplastic conditions. The book provides a detailed description of the surgical pathology of thyroid diseases side by side with major advances in immunohistochemistry and molecular genetics that can be used in evaluating thyroid tumors and non-neoplastic diseases.
Download or read book The Genetics of Complex Thyroid Diseases written by T. Akamizu and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid developments in molecular genetics have clarified many of the muta tions in monogenic thyroid diseases over the last two decades; now the target of molecular thyroid genetics has become the oligogenic thyroid diseases. These include the autoimmune thyroid diseases and familial thyroid cancers, both of which are much commoner than the monogenic diseases. However, the method ological approach to the genetics of these more complex diseases is still far from being well established. Although the discovery of susceptibility genes has been partially accomplished in complex diseases such as asthma, Crohn's dis ease, and types I and II diabetes mellitus, the elucidation of susceptibility genes in complex diseases remains a major challenge. This volume contains papers presented at the International Symposium on the Genetics of Complex Thyroid Diseases. This meeting was held in association with the International Thyroid Congress in Kyoto in October 2000 and sup ported in part by the Japan Intractable Diseases Research Foundation and Knoll Pharmaceuticals Inc. The symposium was the first international symposium con cerning the genetics of complex thyroid diseases and was restricted to the study of the autoimmune thyroid diseases and familial thyroid cancer. Twenty distin guished researchers from the United States, the United Kingdom, France, Ger many, Italy, and Japan were invited. Each presentation precipitated intense dis cussion and there was much consensus during the meeting. Nevertheless, this volume will leave the reader with a clear understanding of how little we still know.
Download or read book Thyroid Pathology written by Kurt W. Schmid and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, a series of excellent textbooks have been published dealing with pathology of the thyroid gland. The present volume of CURRENT TOPICS IN PATHOLOGY provides further information for both pathologists and clinicians interested in the thyroid gland. The contributions deal with surgical pathology of the thyroid as well as with basic aspects of thyroid metabolism, hormone transport, and growth factors in thyroid cells. The topics covered in this book should mainly be considered as adjuncts to common textbooks on thyroid pathology. The contributions should help pathologists in their routine diagnosis and should stimulate further thyroid research.
Download or read book Molecular Diagnostics in Pathology written by Cecilia M. Fenoglio-Preiser and published by . This book was released on 1991 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diagnostic Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2023-10-18 with total page 846 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease. - Includes new material on mass spectrometry for infectious diseases, microbiome, homology-directed repair for PARPi, whole genome sequencing for constitutional testing, and much more - Provides insights on the value of the molecular test in comparison to traditional methods, which include speed, precision, sensitivity and clinical impacts for the patient - Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis and classification in the clinical workup of a patient - Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for the prognostication of disease
Download or read book Rare Tumors of the Thyroid Gland written by José Manuel Cameselle-Teijeiro and published by Springer. This book was released on 2017-09-20 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book documents the most important clinicopathological features of rare thyroid tumours with an emphasis (and ample documentation) on their histological and immunohistochemical aspects. Whenever necessary, namely for differential diagnosis and/or therapy purposes, molecular data are also highlighted. In order to understand the histogenesis of rare lesions and to be able to make a differential diagnosis, the editors use the WHO book for endocrine tumours (in preparation) as a framework for classifying thyroid tumours. In addition to characterizing the main histotypes of thyroid tumours, this book also provides detailed information on how to approach the diagnosis of tumours according to the major morphological/immunohistochemical characteristics, the predominant morphology and whether or not they are hereditary. This book is a valuable learning tool for those involved in the differential diagnosis of thyroid lesions.
Download or read book Diagnostic Pathology Head and Neck E Book written by Lester D. R. Thompson and published by Elsevier Health Sciences. This book was released on 2016-04-20 with total page 1193 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the highly regarded Diagnostic Pathology series, this updated volume is a visually stunning, easy-to-use reference covering all aspects of head and neck pathology. Outstanding images—including gross and microscopic pathology, a wide range of stains, and detailed medical illustrations—make this an invaluable diagnostic aid for every practicing pathologist, resident, or fellow. This second edition incorporates the most recent clinical, pathological, histological, and molecular knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Highly templated text allows for quicky, easy reference. As always, Amirsys titles are image-rich. Thoroughly updated content throughout including new coverage of oropharyngeal carcinoma; HPV-associated, mammary analogue secretory carcinoma; EWSR1 driven tumors; molecular pathways as targets for salivary duct carcinoma; and much more High-quality, carefully annotated color images (50% new!) provide clinically and diagnostically important information on more than 315 new and evolving entities of the head and neck and endocrine organs State-of-the-art coverage of tumors, tumor development, and tumor genetics as well as normal histology, genetic testing, and new immunohistochemistry studies Fully integrated, searchable, and linked content between differential diagnostic categories is perfectly suited for residents, while updated genetic testing algorithms, new images, and outstanding graphics make this text ideal for both residents and practitioners Supporting studies are placed into clinical context, with tables and molecular flow charts that assist with management decisions and prognostic outcome predictions Time-saving reference features include bulleted text, a variety of test data tables, key facts in each chapter, annotated images, and an extensive index Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and references from the book on a variety of devices.
Download or read book Pathology of the Thyroid written by Virginia A. LiVolsi and published by Saunders. This book was released on 2007-10 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume in the Major Problems of Pathology series covers the various aspects of thyroid pathology with an emphasis on aids to differential diagnosis. The book stresses morphologic aspects of thryroid diseases. It is illustrated and extensively referenced. It features a new chapter on molecular biology of thyroid pathology and expanded coverage of evaluation of oncogenes in thyroid neoplasm, as well as studies of clonality in thyroid nodules and neoplasms, and immunogenetics of autoimmune disease. All illustrations are updated, including an additional 12 new color plates!
Download or read book Endocrine written by Vania Nosé and published by Lippincott Williams & Wilkins. This book was released on 2012 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diagnostic Pathology: Endocrine features a careful review of the top 125 endocrine pathology diagnoses. Written by well known experts in endocrine pathology, this 580-page book helps surgical pathologists, fellows, and residents master required knowledge in all areas of endocrine pathology, including thyroid, parathyroid, pituitary, adrenal, pancreas, skin, and inherited tumor syndromes. The diagnoses are conveniently grouped according to the gland involved. Each diagnosis includes definitions, terminology, etiology, pathogenesis, demographics, clinical presentations, therapy, prognosis, gross and microscopic pathology, differential diagnoses, and special studies including immunohistochemistry and molecular/genetics. Every diagnosis is discussed in concise, bulleted text that highlights the most diagnostically significant factors. Augmenting the text discussion are over 2,400 gorgeous medical images, including clinical images, gross pathology, histology, and a wide range of special and immunohistochemical stains. Each image is carefully annotated to highlight the most diagnostically significant factors. Lastly, this book features the classic benefits of all Amirsys titles, including time-saving bulleted text, Key Facts in each chapter, stunning annotated images, extensive index, and Amirsys eBook Advantage, an online version of the print book with larger images and fully searchable text.
Download or read book Management of Differentiated Thyroid Cancer written by Anne T. Mancino and published by Springer. This book was released on 2018-06-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive, state-of-the art review of this field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in thyroid cancer. The book reviews new data about molecular genetics and molecular diagnostic approaches, covers diagnosis and treatment of localized disease, and conventional and newer therapies for dealing with recurrent and metastatic disease. Areas of controversy, with expert opinions from both outlooks, are also covered. Management of Differentiated Thyroid Cancer serves as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information.
Download or read book Pathology and Molecular Biology of Malignant Thyroid Tumours written by King-Yin Alfred Lam and published by Open Dissertation Press. This book was released on 2017-01-27 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Pathology and Molecular Biology of Malignant Thyroid Tumours" by King-yin, Alfred, Lam, 林敬賢, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled Pathology and molecular biology of malignant thyroid tumours submitted by Alfred King Yin Lam for the degree of Doctor of Medicine at the University of Hong Kong in August 2004 Thyroid cancer is the most common endocrine malignancy in Hong Kong. The thesis aims to delineate the clinicopathological features and molecular biology of malignant thyroid tumours in Hong Kong Chinese. Over a 30-years study period, 872 primary cancers and 140 secondary cancers of the thyroid gland were obtained in the pathology files of Queen Mary Hospital. The different types of malignant thyroid tumours may be difficult to differentiate from each other. Carcinomas comprised 97.3% of the primary thyroid cancers. The thyroid carcinomas included 652 papillary carcinomas (74.8%), 129 follicular carcinomas (14.8%), 22 poorly-differentiated carcinomas (2.5%), 38 undifferentiated carcinomas (4.4%), 4 squamous cell carcinomas (0.5%) and 2 carcinomas showing thymus-like differentiation (0.2%). The other malignant thyroid tumours included 23 lymphomas (2.6%) and two sarcomas (0.1%). The different malignant thyroid tumours had diverse pathological features and clinical behaviour. Cytokeratins expression profile was different in different types of thyroid carcinomas. Strong cytokeratin 19 expression was noted in papillary carcinoma, squamous cell carcinoma and carcinoma showing thymus-like differentiation of thyroid. Cytokeratin 10/13 was expressed in some undifferentiated carcinomas of thyroid and not in other thyroid carcinomas. The negative expression of cytokeratin 10/13 in primary squamous cell carcinoma of thyroid was a useful finding to differentiate from the positive expression in metastatic squamous cell carcinoma from upper aerodigestive tract. Cytokeratin 18 was positive in carcinomas of thymus-like differentiation of thyroid and was negative in squamous cell carcinomas of thyroid. p53 expression was seen in undifferentiated carcinomas and squamous cell carcinomas but not in other thyroid carcinomas. Also, the p53 expression was associated with tumour differentiation in primary squamous cell carcinomas of thyroid. RET oncogene activation was often detected in papillary thyroid carcinoma. The oncogene activation was seen more often in conventional papillary carcinoma. Telomerase activity was infrequently reactivated in thyroid cancers. Epstein Barr virus was detected in thyroid lymphomas but not in thyroid carcinomas showing thymus-like differentiation. The Epstein Barr virus genes expression in thyroid lymphomas showed type II latency pattern. In summary, identification of the different histological types of malignant thyroid tumours is mandatory for in depth medical research. The study of pathology and molecular biology of malignant thyroid tumours allows better understanding and management of the diseases. DOI: 10.5353/th_b2986782 Subjects: Thyroid gland - Cancer - Molecular aspects
Download or read book The Bethesda System for Reporting Thyroid Cytopathology written by Syed Z. Ali and published by Springer Science & Business Media. This book was released on 2010-03-20 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas is the offspring of the “The National Cancer Institute (NCI) Thyroid Fine Needle Aspiration (FNA) State of the Science Conference,” hosted by the NCI and organized by Dr. Andrea Abati. Preparations for the conference began 18 months earlier with the designation of a steering committee and the establishment of a dedicated, p- manent web site. The meeting took place on October 22 and 23, 2007 in Bethesda, Maryland and was co-moderated by Susan J. Mandel and Edmund S. Cibas. The discussions and conclusions regarding terminology and morphologic criteria 1, 2 from the meeting were summarized in publications by Baloch et al. and form the framework for this atlas. The atlas is organized by the general categories of “Nondiagnostic,” “Benign,” “Follicular Neoplasm/Suspicious for a Follicular Neoplasm”, “Suspicious for Malignancy,” and “Malignant,” and it includes the defi- tions and morphologic criteria of these categories as set forth by Baloch et al. The majority of the conference participants also agreed on a category of “undetermined significance,” which is incorporated in this atlas (Chap. 4). It is critical that the cytopathologist communicate thyroid FNA interpretations to the referring physician in terms that are succinct, unambiguous, and helpful clinically. We recognize that the terminology used here is a flexible framework that can be modified by individual laboratories to meet the needs of their providers and the patients they serve.
Download or read book Endocrine Pathology written by Lester D. R. Thompson and published by Churchill Livingstone. This book was released on 2006 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: With abundant at-a-glance tables, the volume reviews normal histology before examining abnormal findings, covers all of the most commonly seen neoplastic and non-neoplastic conditions of the endocrine system, and uses a consistent, user-friendly format to explore each entity's clinical features pathologic features (gross and microscopic) ancillary studies differential diagnoses and prognostic and therapeutic considerations. Heavily illustrated.
