Download or read book Developmental Mutants of Neurospora Crassa written by Peter James Russell and published by . This book was released on 1972 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Study of Developmental Mutants of Neurospora written by Dennis Raymond Novak and published by . This book was released on 1971 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic and Physiological Studies of Some Slow Growing Mutants of Neurospora Crassa written by Joan (Leopold) Muneta and published by . This book was released on 1959 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Genetics of a Group of Biochemical Mutants of Neurospora Crassa written by Mary Bowman Houlahan and published by . This book was released on 1944 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Genetics of Methionineless Mutants of Neurospora Crassa written by Helen Rumsey Buss and published by . This book was released on 1944 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Genetic Study of Albino Mutants of Neurospora Crassa written by Mary Virginia Griggs Hungate and published by . This book was released on 1945 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dose rate Effects on Inactivation and Mutation induction in Neurospora Crassa written by and published by . This book was released on 1967 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Reverse Mutation Studies of Colonial Mutants of Neurospora Crassa written by Clint William Magill and published by . This book was released on 1969 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Investigations of the Lysine requiring Mutants of Neurospora Crassa written by August Henry Doermann and published by . This book was released on 1946 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Structure and Developmental Regulation of a Gene Expressed During Conidiation in Neurospora Crassa written by Brian T. White and published by . This book was released on 1991 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biochemical Genetics of Tryptophanless Mutants of Neurospora Crassa written by Dorothy Lorraine Newmeyer and published by . This book was released on 1951 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ultrastructural aspects of development in the slime mutant sl 327 of Neurospora crassa written by Wallace Barry Van Winkle and published by . This book was released on 1970 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic Control of Morphological Differentiation in Neurospora Crassa written by Matthew Lawrence Springer and published by . This book was released on 1991 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Isolation and Characterization of Cytoplasmic Mutants in Neurospora Crassa written by Helmut Bertrand and published by . This book was released on 1971 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Biochemistry and Genetics of Threonine requiring Mutants of Neurospora Crassa written by Howard Jones Teas and published by . This book was released on 1947 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Characterization of Neurospora Crassa and Fusarium Graminearum Mutants Defective in Repeat induced Point Mutation written by Kyle R. Pomraning and published by . This book was released on 2012 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mutation of repetitive DNA by repeat-induced point mutation (RIP) is a process that occurs in many filamentous fungi of the Ascomycota during the sexual cycle. Concurrently, direct DNA repeats are often deleted by homologous recombination at high frequency during the sexual cycle. Thus, the processes of RIP and deletion compete to either mutate or remove repetitive DNA from the genome of filamentous fungi during sexual cycles. Both processes contribute to genome streamlining by controlling proliferation of transposable elements and by limiting expansion of gene families. While the genetic requirements for deletion by homologous recombination are well known, the mechanism behind the specific detection and mutation of repetitive DNA by RIP has yet to be elucidated as only a single gene essential for RIP, rid, has been identified. We have developed Fusarium graminearum as a model organism for the study of RIP by showing that it mutates repetitive DNA frequently during the sexual cycle and that the mutations due to RIP are dependent on rid. Further, we have sequenced a genetic mapping strain of F. graminearum (00-676-2) and identified 62,310 single nucleotide polymorphisms (SNPs) compared to the reference strain (PH-1). The SNP map will be useful for quickly mapping new mutants by bulk segregant analysis and high-throughput sequencing for which bioinformatic tools were specifically developed. The groundwork has thus been laid for identification of novel RIP mutants in F. graminearum, which being homothallic has a major advantage for identification of recessive mutations. We used a forward genetics approach to shed light on the mechanism of RIP in Neurospora crassa. Two rrr mutants that dominantly r̲educe R̲IP and r̲ecombination were characterized and identified as different mutated alleles of the same gene, rrr-1[superscript L496P] and rrr-1[superscript G325N] by bulk segregant analysis and high-throughput sequencing. Bioinformatic characterization suggests RRR-1 belongs to a previously uncharacterized group of dynamin-like proteins, which are generally involved in membrane fission and fusion. RRR-1-GFP localizes to the nuclear membrane, but not DNA, suggesting it affects RIP and recombination frequency indirectly by altering nuclear membrane dynamics during sexual development and thereby altering temporal aspects of RIP and recombination. We used a reverse genetics approach to determine whether high frequency RIP and homologous recombination of repetitive DNA during the sexual cycle are linked mechanistically or spatio-temporally. We tested strains where genes important for deletion by homologous recombination were knocked out and found all to be completely RIP competent except mre11, which, while sterile in homozygous deletion crosses, displayed lower RIP frequency in heterozygous crosses. This suggests that mre11 has roles in homologous recombination as well as non-homologous end joining may be important for RIP. Collectively, this work developed methods for efficiently mapping mutations and identified a novel protein that reduces RIP and recombination frequency but did not identify any mechanistic link between the two processes.
Download or read book The Biochemical Genetics of a Mutant of Neurospora Crassa Requiring Serine Or Glycine written by Frank P. Hungate and published by . This book was released on 1946 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt:
