Download or read book Development and Application of Novel Genome Engineering Tools in Microbial Biotechnology written by Jiazhang Lian and published by Frontiers Media SA. This book was released on 2021-01-20 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genome Engineering via CRISPR Cas9 System written by Vijai Singh and published by Academic Press. This book was released on 2020-02-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields.
Download or read book Genome Editing in Bacteria Part 2 written by Prakash M. Halami and published by Bentham Science Publishers. This book was released on 2024-04-24 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a comprehensive review of genome editing in bacteria. The multi-part book meticulously consolidates research findings and insights on the applications of bacteria across several industries, including food processing and pharmaceutical development. The book covers four overarching themes for readers: a historical perspective of genome editing, genome editing in probiotics, applications of genome editing in agricultural microbiology and genetic engineering in environmental microbiology. The editors have also compiled chapters that provide an in-depth analysis of gene regulation and metabolic engineering through genome editing tools for specific bacteria. Key topics in part 2: - Targeting pathogenic microbes for plants and animals using CRISPR-CAS - Genome editing microbes to improve crop yield plant growth for sustainable agriculture - Applications of genome editing for bioremediation - Microbial genome editing for environmental bioprocessing - Genetic engineering for methanotrophs - Genome engineering in Cyanobacteria - Genome editing in Streptomyces Genome Editing in Bacteria is a definitive reference for scholars, researchers and industry professionals navigating the forefront of bacterial genomics.
Download or read book Biotechnology and Genetic Engineering written by Willy Gibson & Clem Koch and published by Scientific e-Resources. This book was released on 2019-11-07 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biotechnology and Genetic Engineering is an important reference tool for students, teachers, physicians, science and technical writers, and anyone looking for a concise source of current information on this fast-breaking field. Biotechnology is the study of science which have discussed over many years but on the other hand, Genetic Engineering is the premature and young branch of science which has many milestones to achieve. Biotechnology deals with a set of biological techniques developed through basic research and now applied to research and product development. It is the means or way of manipulating life forms (organisms) to provide desirable products for man's use. For example, beekeeping and cattle breeding could be considered to be biotechnology related endeavors. Basically, Genetic Engineering is the modern modification and subspecialty of the branch of science called biotechnology. It deals and concerned with the specific and targeted modifications of the genetic material of bacteria and plants to stimulate them synthesize or biosynthesize desired products, Genetic Engineering is helping a lot to attain the results which are so much beneficial and helpful to the mankind, either it implies the genetic engineering of plants or animals or to microbes to help and improve the quality and quantity of food sometimes. Production associated with food items as well as drugs continues to be the principle exercise carried out by means of genetic engineering. This book covers all of the fundamental principles of the modern topics and has been presented in a very simple manner for self-study and provides comprehensive coverage of the standard topics.
Download or read book Genome Editing in Bacteria Part 1 written by Prakash M. Halami, Aravind Sundararaman and published by Bentham Science Publishers. This book was released on 2024-02-14 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a comprehensive review of genome editing in bacteria. The multi-part book meticulously consolidates research findings and insights on the applications of bacteria across several industries, including food processing and pharmaceutical development. The book covers four overarching themes for readers: a historical perspective of genome editing, genome editing in probiotics, applications of genome editing in agricultural microbiology and genetic engineering in environmental microbiology. The editors have also compiled chapters that provide an in-depth analysis of gene regulation and metabolic engineering through genome editing tools for specific bacteria. Key topics in part 1: - An Overview of advances in CRISPR-CAS research - Applications of CRISPR/CAS9-based genome editing for industrial microorganisms - Gut microbiome modulation to address gut dysbiosis - Bifidobacterium genome editing for probiotic development and metabolic engineering. - Insights into the use of lactic acid bacteria as starter cultures in the food - Genome editing of vegetable-derived L. Plantarum - Genome editing in Bacillus Licheniformis Genome Editing in Bacteria is a definitive reference for scholars, researchers and industry professionals navigating the forefront of bacterial genomics. Readership Scholars and professionals interested in bacterial genomics.
Download or read book Genome Editing in Bacteria Part 2 written by Prakash M. Halami; and published by Bentham Science Publishers. This book was released on 2024-04-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a comprehensive review of genome editing in bacteria. The multi-part book meticulously consolidates research findings and insights on the applications of bacteria across several industries, including food processing and pharmaceutical development. The book covers four overarching themes for readers: a historical perspective of genome editing, genome editing in probiotics, applications of genome editing in agricultural microbiology and genetic engineering in environmental microbiology. The editors have also compiled chapters that provide an in-depth analysis of gene regulation and metabolic engineering through genome editing tools for specific bacteria. Key topics in part 2: - Targeting pathogenic microbes for plants and animals using CRISPR-CAS - Genome editing microbes to improve crop yield plant growth for sustainable agriculture - Applications of genome editing for bioremediation - Microbial genome editing for environmental bioprocessing - Genetic engineering for methanotrophs - Genome engineering in Cyanobacteria - Genome editing in Streptomyces Genome Editing in Bacteria is a definitive reference for scholars, researchers and industry professionals navigating the forefront of bacterial genomics. Readership Scholars and professionals interested in bacterial genomics.
Download or read book Advances in Synthetic Biology written by Vijai Singh and published by Springer Nature. This book was released on 2020-04-13 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the design of emerging conceptual tools, technologies and systems including novel synthetic parts, devices, circuits, oscillators, biological gates, and small regulatory RNAs (riboregulators and riboswitches), which serve as versatile control elements for regulating gene expression. Synthetic biology, a rapidly growing field that involves the application of engineering principles in biology, is now being used to develop novel systems for a wide range of applications including diagnostics, cell reprogramming, therapeutics, enzymes, vaccines, biomaterials, biofuels, fine chemicals and many more. The book subsequently summarizes recent developments in technologies for assembling synthetic genomes, minimal genomes, synthetic biology toolboxes, CRISPR-Cas systems, cell-free protein synthesis systems and microfluidics. Accordingly, it offers a valuable resource not only for beginners in synthetic biology, but also for researchers, students, scientists, clinicians, stakeholders and policymakers interested in the potential held by synthetic biology.
Download or read book Genome Editing Tools and Gene Drives written by Reagan Mudziwapasi and published by CRC Press. This book was released on 2021-10-18 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome-editing methods are becoming routine tools for molecular and cell biologists. Such tools include ZFNs, CRISPR, megaTALs and TALENs. These tools are revolutionizing the creation of precisely manipulated genomes to modify the characteristics of organisms or cells. Additionally, gene drives have altered the way we understand inheritance laws. They give us the ability to have total control of the inheritance of traits of choice and importance. This succinct volume summarizes the history, principles and applications – as well as the advantages and disadvantages – of each of these tools and various kinds of gene drives. The book is part of a program to produce books helpful to students and faculties of science at colleges and universities. This volume in the Pocket Guides to Biomedical Sciences series will help demystify these technologies. The book fills the gap between established conventional methods and the novel and exciting newly introduced tools of genome editing and gene drives. It will help young scientists understand the emerging genome-editing tools and gene drives, thereby promoting related research and adoption. Key Features Extensively reviews the current genome-editing tools and gene drives Clarifies the targeting mechanisms and specificity of genome-editing tools Details many different types of natural and synthetic gene drives Highlights concerns with gene drives and genome-editing tools Related Titles Brown, T. A. Genomes 4 (ISBN 978-0-8153-4508-4) Samuelsson, T. The Human Genome in Health and Disease: A Story in Four Letters (ISBN 978-0-8153-4591-6) Soh, J., et al. Genome Annotation (ISBN 978-1-4398-4117-4)
Download or read book Bioremediation of Pollutants written by Vimal Chandra Pandey and published by Elsevier. This book was released on 2020-05-30 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bioremediation of Pollutants: From Genetic Engineering to Genome Engineering provides insights into genetic and genome engineering strategies in bioremediation, covering a wide range of microorganisms that are key to the removal of pollutants. The book includes discussions on root engineering, transgenic plants, metagenomics, bioreactors, molecular biology tools, genome editing, synthetic biology, microbial indicators, biosurfactants, biofilms, genetically modified organisms, and engineered fungi and bacteria. Presented by top experts in the field, this resource captures the essence and diversity of bioremediation methodologies in a single source. Students and beginners in environmental science, researchers, soil scientists, genetic and genome engineers, stakeholders and policymakers interested in improving this rapidly growing area of research will find this resource extremely useful. Draws together research from eminent scientists from across the globe in the areas of phytoremediation and microbial remediation Includes case studies of engineered bacterial remediation Covers the genome editing CRISPR-Cas9 system that has been less explored in plants and microorganisms
Download or read book Microbial Production written by Hideharu Anazawa and published by Springer Science & Business Media. This book was released on 2014-02-20 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial production: From genome design to cell surface engineering affords a comprehensive review of novel technology and approaches being implemented for manufacturing microorganisms, written by specialists in both academia and industry. This book is divided into three sections: the first includes technology for improvement of fermentation strains and many supporting technologies and information; the second examines novel technology useful for analysis of cell activities, analyzing gene function, and designing genomes of producer strains; and finally, a discussion of the practical application of the techniques and success case studies in many fields of bio-production, such as microbiological production, pharmaceuticals, chemicals, foods and cosmetics.
Download or read book Genome Engineering written by and published by Elsevier. This book was released on 2023-05-15 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Engineering, Volume 52 in the Methods in Microbiology series, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors. Topics covered include Whole genome transplantation in Mollicutes, Natural transformation as a tool in Acinetobacter baylyi: evolution by amplification of gene copy number, Natural transformation as a tool in Acinetobacter baylyi: streamlined engineering and mutational analysis, Methods to characterize cryptic biosynthetic gene clusters in Streptomyces, Genome engineering in bacteria: current and prospective applications, Tools for activation and identification of cryptic biosynthesis pathways in Streptomyces. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Microbiology serials Includes the latest information on Genome Engineering
Download or read book Strain Engineering written by James A. Williams and published by Humana Press. This book was released on 2016-08-23 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Classical methods for microbial strain engineering, used to improve the production of bioproducts, have serious drawbacks and have been found to be unsuitable for complex strain development applications. In Strain Engineering: Methods and Protocols, powerful new genetic engineering-based strain engineering methods are presented for rational modification of a variety of model organisms. These methods are particularly powerful when utilized to manipulate microbes for which sequenced and annotated genomes are available. Collectively, these methods systematically introduce genome alterations in a precise manner, allowing the creation of novel strains carrying only desired genome alterations. In the first section, E. coli-based bacterial strain engineering strategies are reviewed, while the second section presents analogous microbial engineering strategies for eukaryotic cells using the yeast Saccharomyces cerevisiae as a model. The third section covers examples of the proliferative adaptations of these base technologies to strain engineer industrially important prokaryotic or eukaryotic microbial systems. Written in the highly successful Methods in Molecular BiologyTM series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Strain Engineering: Methods and Protocols serves as an ideal guide to scientists in academia, pharmaceutical science, and biotechnology who perform microbial strain engineering.
Download or read book Synthetic Biology written by Huimin Zhao and published by Academic Press. This book was released on 2013-03-21 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthetic Biology provides a framework to examine key enabling components in the emerging area of synthetic biology. Chapters contributed by leaders in the field address tools and methodologies developed for engineering biological systems at many levels, including molecular, pathway, network, whole cell, and multi-cell levels. The book highlights exciting practical applications of synthetic biology such as microbial production of biofuels and drugs, artificial cells, synthetic viruses, and artificial photosynthesis. The roles of computers and computational design are discussed, as well as future prospects in the field, including cell-free synthetic biology and engineering synthetic ecosystems. Synthetic biology is the design and construction of new biological entities, such as enzymes, genetic circuits, and cells, or the redesign of existing biological systems. It builds on the advances in molecular, cell, and systems biology and seeks to transform biology in the same way that synthesis transformed chemistry and integrated circuit design transformed computing. The element that distinguishes synthetic biology from traditional molecular and cellular biology is the focus on the design and construction of core components that can be modeled, understood, and tuned to meet specific performance criteria and the assembly of these smaller parts and devices into larger integrated systems that solve specific biotechnology problems. Includes contributions from leaders in the field presents examples of ambitious synthetic biology efforts including creation of artificial cells from scratch, cell-free synthesis of chemicals, fuels, and proteins, engineering of artificial photosynthesis for biofuels production, and creation of unnatural living organisms Describes the latest state-of-the-art tools developed for low-cost synthesis of ever-increasing sizes of DNA and efficient modification of proteins, pathways, and genomes Highlights key technologies for analyzing biological systems at the genomic, proteomic, and metabolomic levels which are especially valuable in pathway, whole cell, and multi-cell applications Details mathematical modeling tools and computational tools which can dramatically increase the speed of the design process as well as reduce the cost of development
Download or read book New and Future Developments in Microbial Biotechnology and Bioengineering written by Ram Prasad and published by Elsevier. This book was released on 2018-02-20 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Crop Improvement through Microbial Biotechnology explains how certain techniques can be used to manipulate plant growth and development, focusing on the cross-kingdom transfer of genes to incorporate novel phenotypes in plants, including the utilization of microbes at every step, from cloning and characterization, to the production of a genetically engineered plant. This book covers microbial biotechnology in sustainable agriculture, aiming to improve crop productivity under stress conditions. It includes sections on genes encoding avirulence factors of bacteria and fungi, viral coat proteins of plant viruses, chitinase from fungi, virulence factors from nematodes and mycoplasma, insecticidal toxins from Bacillus thuringiensis, and herbicide tolerance enzymes from bacteria. Introduces the principles of microbial biotechnology and its application in crop improvement Lists various new developments in enhancing plant productivity and efficiency Explains the mechanisms of plant/microbial interactions and the beneficial use of these interactions in crop improvement Explores various bacteria classes and their beneficial effects in plant growth and efficiency
Download or read book Microbial Biotechnology Basic Research and Applications written by Joginder Singh and published by Springer Nature. This book was released on 2020-07-07 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial biotechnology is an important area that promotes advanced research into using microbes for value-added products, human nutrition, and the overall wellbeing of society. This book presents the latest information on the use of microbes for sustainable development, and highlights state-of-the-art biotechnological techniques used to harness microbial biotechnological traits on a commercial scale. Gathering contributions from authoritative researchers in the field, it addresses recent advances in microbial biotechnological approaches that offer sustainable options for future generations. Exploring a broad range of microbial products and their uses, the book specifically places emphasis on the application of microorganisms in healthcare, the environment and industry. It also discusses various compound classes derived from microbial metabolites. Pursuing a holistic approach to recent advances in the utilization of various microbes as biotechnological tools, the book also covers traditional uses, and explores emerging strategies to harness their full potential. Accordingly, it offers a valuable resource for researchers and graduate students alike.
Download or read book Genome Engineering for Crop Improvement written by Santosh Upadhyay and published by John Wiley & Sons. This book was released on 2020-12-31 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, significant advancements have been made in the management of nutritional deficiency using genome engineering—enriching the nutritional properties of agricultural and horticultural crop plants such as wheat, rice, potatoes, grapes, and bananas. To meet the demands of the rapidly growing world population, researchers are developing a range of new genome engineering tools and strategies, from increasing the nutraceuticals in cereals and fruits, to decreasing the anti-nutrients in crop plants to improve the bioavailability of minerals and vitamins. Genome Engineering for Crop Improvement provides an up-to-date view of the use of genome editing for crop bio-fortification, improved bioavailability of minerals and nutrients, and enhanced hypo-allergenicity and hypo-immunogenicity. This volume examines a diversity of important topics including mineral and nutrient localization, metabolic engineering of carotenoids and flavonoids, genome engineering of zero calorie potatoes and allergen-free grains, engineering for stress resistance in crop plants, and more. Helping readers deepen their knowledge of the application of genome engineering in crop improvement, this book: Presents genetic engineering methods for developing edible oil crops, mineral translocation in grains, increased flavonoids in tomatoes, and cereals with enriched iron bioavailability Describes current genome engineering methods and the distribution of nutritional and mineral composition in important crop plants Offers perspectives on emerging technologies and the future of genome engineering in agriculture Genome Engineering for Crop Improvement is an essential resource for academics, scientists, researchers, agriculturalists, and students of plant molecular biology, system biology, plant biotechnology, and functional genomics.
Download or read book Genome Editing and Engineering written by Krishnarao Appasani and published by Cambridge University Press. This book was released on 2018-08-23 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in genome editing tools using endonucleases such as TALENs, ZFNs, and CRISPRs, combined with genomic engineering technologies, have opened up a wide range of opportunities from applications in the basic sciences and disease biology research, to the potential for clinical applications and the development of new diagnostic tools. This complete guide to endonuclease-based genomic engineering gives readers a thorough understanding of this rapidly expanding field. Chapters cover the discovery, basic science, and application of these techniques, focusing particularly on their potential relevance to the treatment of cancer, and cardiovascular and immunological disease. The final section discusses the legal and ethical issues which accompany the technology. Providing authoritative coverage of the potential that genome editing and engineering have, this is an ideal reference for researchers and graduate students and those working in the biotechnology and pharmaceutical industries, as well as in a clinical setting.
