Download or read book Determination of particle sizes in the pharmaceutical industry written by Karin Liltorp and published by BoD – Books on Demand. This book was released on 2014-03-03 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: At Particle Analytical, we have been working with determination of particle sizes for the pharmaceutical industry since 2000. Our customers have in general showed a large interest for an introduction to this area from a down-to-earth and practical perspective. The intended readers of this booklet are pharmacists and technicians working with determination of particles sizes. This booklet is not meant as a thorough introduction into theory behind determination of particle sizes, and only a limited number of references will be given: The booklet is primarily based on our own experiences and is a practical introduction to the area with a brief introduction to "why" and "how" in determination of particle sizes.
Download or read book Particle Size Analysis In Pharmaceutics And Other Industries Theory And Practice written by Clive Washington and published by CRC Press. This book was released on 1992-06-30 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent major advances in particle size analysis, particularly with regard to its application in the pharmaceutical and related industries, provides justification for this title. It is a book for technicians and senior technicians, project and development managers, and formulation More...development scientists in a wide range of industries, pharmace
Download or read book Particle Size Analysis in the Pharmaceutical Industry written by E. D. Dymock and published by . This book was released on 1964 with total page 86 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Characterization of Pharmaceutical Nano and Microsystems written by Leena Peltonen and published by John Wiley & Sons. This book was released on 2020-12-21 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn about the analytical tools used to characterize particulate drug delivery systems with this comprehensive overview Edited by a leading expert in the field, Characterization of Pharmaceutical Nano- and Microsystems provides a complete description of the analytical techniques used to characterize particulate drug systems on the micro- and nanoscale. The book offers readers a full understanding of the basic physicochemical characteristics, material properties and differences between micro- and nanosystems. It explains how and why greater experience and more reliable measurement techniques are required as particle size shrinks, and the measured phenomena grow weaker. Characterization of Pharmaceutical Nano- and Microsystems deals with a wide variety of topics relevant to chemical and solid-state analysis of drug delivery systems, including drug release, permeation, cell interaction, and safety. It is a complete resource for those interested in the development and manufacture of new medicines, the drug development process, and the translation of those drugs into life-enriching and lifesaving medicines. Characterization of Pharmaceutical Nano- and Microsystems covers all of the following topics: An introduction to the analytical tools applied to determine particle size, morphology, and shape Common chemical approaches to drug system characterization A description of solid-state characterization of drug systems Drug release and permeation studies Toxicity and safety issues The interaction of drug particles with cells Perfect for pharmaceutical chemists and engineers, as well as all other industry professionals and researchers who deal with drug delivery systems on a regular basis, Characterization of Pharmaceutical Nano- and Microsystems also belongs on bookshelves of interested students and faculty who interact with this topic.
Download or read book Particle Size Analysis written by N G Stanley-Wood and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: Particle Size Analysis reviews the development of particle characterization over the past 25 years and also speculates on its future. Interest in the subject has increased enormously over the years and this book highlights the changes and advances made within the field. This book is comprehensive in its coverage of particle size analysis and includes contributions on such characterization techniques as microscopy using fractal analysis, light diffraction, light scattering with the phase doppler technique, light observation, and photon correlation spectroscopy. A number of chapters address the interest in on-line in-stream particle size analysis and illustrate the progress being made in achieving this long sought after ideal of in-situ in-process particle characterization. Applications to other technological fields are detailed by chapters covering biological systems and the pharmaceutical industry. The subject of surface area determination is considered with particular emphasis on the measurements on porosity of powders, the characterization and comparability of reference materials, and the need for standards. Particle Size Analysis should provide stimulating reading for technologists, scientists, and engineers involved in particle characterization and powder technology worldwide.
Download or read book Particle Size Measurement in the Pharmaceutical Industry written by Philip E. Plantz and published by . This book was released on 1995 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Particle Size Measurement in the Pharmaceutical Industry written by Philip E. Plantz and published by . This book was released on 1998-05 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Particle Size Measurements written by Henk G. Merkus and published by Springer Science & Business Media. This book was released on 2009-01-07 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the practical aspects of particle size measurement: a major difference with existing books, which have a more theoretical approach. Of course, the emphasis still lies on the measurement techniques. For optimum application, their theoretical background is accompanied by quantitative quality aspects, limitations and problem identification. In addition the book covers the phenomena of sampling and dispersion of powders, either of which may be dominant in the overall analysis error. Moreover, there are chapters on the general aspects of quality for particle size analysis, quality management, reference materials and written standards, in- and on-line measurement, definitions and multilingual terminology, and on the statistics required for adequate interpretation of results. Importantly, a relation is made to product performance, both during processing as well as in final application. In view of its set-up, this book is well suited to support particle size measurement courses.
Download or read book Pharmaceutical Particulate Matter written by Thomas A. Barber and published by Interpharm CRC. This book was released on 1993 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Particles and Nanoparticles in Pharmaceutical Products written by Henk G. Merkus and published by Springer. This book was released on 2018-09-06 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume brings together the expertise of numerous specialists on the topic of particles – their physical, chemical, pharmacological and toxicological characteristics – when they are a component of pharmaceutical products and formulations. The book discusses in detail properties such as the composition, size, shape, surface properties and porosity of particles with respect to how they impact the formulations and products in which they are used and the effective delivery of pharmaceutical active ingredients. It considers all dosage forms of pharmaceuticals involving particles, from powders to tablets, creams to ointments, and solutions to dry-powder inhalers, also including the latest nanomedicine products. Further, it discusses examples of particle toxicity, as well as the important subject of pharmaceutical industry regulations, guidelines and legislation. The book is of interest to researchers and practitioners who work on testing and developing pharmaceutical dosage and delivery systems.
Download or read book Solid State Development and Processing of Pharmaceutical Molecules written by Michael Gruss and published by John Wiley & Sons. This book was released on 2021-11-15 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solid State Development and Processing of Pharmaceutical Molecules A guide to the lastest industry principles for optimizing the production of solid state active pharmaceutical ingredients Solid State Development and Processing of Pharmaceutical Molecules is an authoritative guide that covers the entire pharmaceutical value chain. The authors—noted experts on the topic—examine the importance of the solid state form of chemical and biological drugs and review the development, production, quality control, formulation, and stability of medicines. The book explores the most recent trends in the digitization and automation of the pharmaceutical production processes that reflect the need for consistent high quality. It also includes information on relevant regulatory and intellectual property considerations. This resource is aimed at professionals in the pharmaceutical industry and offers an in-depth examination of the commercially relevant issues facing developers, producers and distributors of drug substances. This important book: Provides a guide for the effective development of solid drug forms Compares different characterization methods for solid state APIs Offers a resource for understanding efficient production methods for solid state forms of chemical and biological drugs Includes information on automation, process control, and machine learning as an integral part of the development and production workflows Covers in detail the regulatory and quality control aspects of drug development Written for medicinal chemists, pharmaceutical industry professionals, pharma engineers, solid state chemists, chemical engineers, Solid State Development and Processing of Pharmaceutical Molecules reviews information on the solid state of active pharmaceutical ingredients for their efficient development and production.
Download or read book Particle size measurement written by Terence Allen and published by Springer. This book was released on 2013-11-21 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although man's environment, from the interstellar dust to the earth beneath his feet, is composed to a large extent of finely divided material, his knowledge of the propert ies of such materials is surprisingly slight. For many years the scientist has accepted that matter may exist as solids, liquids or gases although the dividing line between the states may often be rather blurred; this classification has been upset by powders, which at rest are solids, when aerated may behave as liquids, and when suspended in gases take on some of the properties of gases. It is now widely recognized that powder technology is a field of study in its own right. The industrial applications of this new science are far reaching. The size of fine particles affects the properties of a powder in many important ways. For example, it determines the setting time of cement, the hiding power of pigments and the activity of chemical catalysts; the taste of food, the potency of drugs and the sintering shrink age of metallurgical powders are also strongly affected by the size of the particles of which the powder is made up. Particle size measurement is to powder technology as thermometry is to the study of heat and is in the same state of flux as thermometry was in its early days. Only in the case of a sphere can the size of a particle be completely described by one number.
Download or read book Powder Sampling and Particle Size Determination written by T. Allen and published by Elsevier. This book was released on 2003-12-09 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: Powder technology is a rapidly expanding technology and nowhere more than in particle characterization. There has been an explosion of new particle measuring techniques in the past ten year particularly in the field of on-line measurement. One of the main aims of this book is to bring the reader up-to-date with current practices. One important area of interest is the improvements in on-line light scattering instruments and the introduction of ultrasonic on-line devices. Another is the introduction of on-line microscopy, which permits shape analysis in conjunction with particle sizing.Schools of powder technology are common in Europe and Japan but the importance of this subject has only recently been recognised in America with the emergence of the Particle Research Centre (PERC) at the University of Florida in Gainsville. - Details all the latest developments in powder technology - Written by established authority on powder technology- A comprehensive text covering all aspects of powder technology and handling of particulate solids including characterization, handling and applications
Download or read book The Role of Microstructure in Topical Drug Product Development written by Nigel Langley and published by Springer. This book was released on 2019-08-07 with total page 199 pages. Available in PDF, EPUB and Kindle. Book excerpt: Following the Semi-solid Microstructure Workshop sponsored by BASF and hosted by the Rutgers Center for Dermal Research, a pharmaceutical product development working group was formed. The group, known as the Q3 Working Group, selected the following five areas of focus: Particle/Globule Size and Distribution, Viscosity/Rheology/Spreadability, In Vitro Testing, State of API, State of Excipients. A committee was appointed for each of these five areas. The committees were tasked to review the literature, identify best practices, list experimental details required for an independent lab to duplicate the test, and propose scientific studies that may meaningfully advance this specific area of focus. Each committee has a chair (or co-chairs) that are the lead author(s) of the chapter. The Q3 Working Group members serve as the critical reviewers of each chapter, making suggestions that improve the quality of the document and that make each of the five chapters uniform in scope and content.Pharmaceutical development scientists that formulate topical products (creams, lotions, gels suspensions, foams, etc) and all the allied raw material suppliers, packaging suppliers, contract laboratories including CROs, CMOs and regulators need access to this book. Overall, the topic of semisolid microstructure is of equal importance to the generic pharmaceutical companies (filing Abbreviated New Drug Applications or ANDAs) and pharmaceutical companies filing New Drug Applications (NDAs). In addition to products applied to the skin, hair, and nails, The Role of Microstructure in Topical Drug Product Development’ crosses over and is essential reading to developers of oral suspensions, ophthalmic ointments and gels, otic suspension, vaginal semisolids and retention enemas.
Download or read book Early Drug Development 2 Volume Set written by Fabrizio Giordanetto and published by John Wiley & Sons. This book was released on 2018-12-10 with total page 810 pages. Available in PDF, EPUB and Kindle. Book excerpt: This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the prediction of pharmacokinetics and -dynamics, as well as that of drug safety. The final section focuses on intellectual property aspects during early clinical development. The emphasis throughout is on recent case studies to exemplify salient points, resulting in an abundance of practice-oriented information that is usually not available from other sources. Aimed at medicinal chemists in industry as well as academia, this invaluable reference enables readers to understand and navigate the challenges in developing clinical candidate molecules that can be successfully used in phase one clinical trials.
Download or read book Particle Size Analysis in Industrial Hygiene written by Leslie Silverman and published by Elsevier. This book was released on 2012-12-02 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: Particle Size Analysis in Industrial Hygiene discusses technical information on particle properties, kinetic behavior, sampling instruments, and interpretation. This book is composed of seven chapters and is prepared by the American Industrial Hygiene Association for the Division of Technical Information, United States Atomic Energy Commission. This monograph is a part of the continuing effort of both organizations to extend the field of technical knowledge and safeguard the health and well-being of persons exposed to toxic or deleterious material. After briefly discussing the fundamental physics and chemistry of aerosol systems, the book goes on describing the analytical methods and instruments for particle size analysis. Such methods include direct and indirect sampling methods as well as automatic counting and sizing instruments. Specific methods considered include sieve analysis, optical and electron microscopy, and scanning electron microscopy. A chapter on particle size interpretation and representation with the use of applied mathematical statistics concepts is also provided. This book also covers a general discussion on typical applications of particle size analysis to industrial hygiene, radiation protection, air pollution control, industrial toxicology, and related areas. This book is an invaluable source for industrial hygienists and to those working in the many disciplines dealing with particle behavior.
Download or read book Particle Size Determination written by Richard Dunbar Cadle and published by . This book was released on 1955 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
