Download or read book Anticancer Agents written by Qiao-Hong Chen and published by MDPI. This book was released on 2021-03-02 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a printed edition of the Special Issue entitled “Anticancer Agents: Design, Synthesis and Evaluation” that was published in Molecules. Two review articles and thirty research papers are included in the Special Issue. Three second-generation androgen receptor antagonists that have been approved by the U.S. FDA for the treatment of prostate cancer have been reviewed. Identification of mimics of protein partners as protein-protein interaction inhibitors via virtual screening has been summarized and discussed. Anticancer agents targeting various protein targets, including IGF-1R, Src, protein kinase, aromatase, HDAC, PARP, Toll-Like receptor, c-Met, PI3Kdelta, topoisomerase II, p53, and indoleamine 2,3-dioxygenase, have been explored. The analogs of three well-known tubulin-interacting natural products, paclitaxel, zampanolide, and colchicine, have been designed, synthesized, and evaluated. Several anticancer agents representing diverse chemical scaffolds were assessed in different kinds of cancer cell models. The capability of some anticancer agents to overcome the resistance to currently available drugs was also studied. In addition to looking into the in vitro ability of the anticancer agents to inhibit cancer cell proliferation, apoptosis, and cell cycle, in vivo antitumor efficacy in animal models and DFT were also investigated in some papers.
Download or read book Design Synthesis and Applications of One Dimensional Chalcogenide Hetero Nanostructures written by Tao-Tao Zhuang and published by Springer. This book was released on 2018-04-07 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis focuses on the design and synthesis of novel one-dimensional colloidal chalcogenide hetero-nanostructures for enhancing solar energy conversion applications. Semiconducting nanomaterials are particular attractive for energy conversion due to the quantum confinement effects dictating their unique optical and electronic properties. Steering the photo-induced charge-flow based on unique bandgap alignment in semiconductor heterojunctions is critical for photo-electric/chemical conversion. The author presents the controllable preparation strategies to synthesize 1D chalcogenide hetero-nanostructures with various fine structures, further been used as excellent template materials for preparing other novel and complex hybrid architectures through a series of chemical transformations. The heterogeneous growth mechanisms of novel hetero-nanostructures is studied for developing a facile and general method to prepare more novel heterostructures. The band gap structure simulations, detailed charge carrier behaviour and unique solar energy conversion properties of the prepared hybrid nanostructures are deeply investigated. This work would open a new door to rationally designing hybrid systems for photo-induced applications.
Download or read book Photo Electrochemical Ammonia Synthesis written by Mohammadreza Nazemi and published by . This book was released on 2021 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book covers the synthesis of novel hybrid plasmonic nanomaterials and their application in photo-electrochemical systems to convert low energy molecules to high value-added molecules and looks specifically at photo-electrochemical nitrogen reduction reaction (NRR) for ammonia synthesis as an attractive alternative to the long-lasting thermochemical process. This book will be of high interest to researchers, advanced students, and industry professionals in working in sustainable energy storage and conversion across the disciplines of Chemical Engineering, Mechanical Engineering, Materials Science and Engineering, Environmental Engineering, and related areas"--
Download or read book Design Synthesis and Application of Novel Conjugated Materials Part II written by Haichang Zhang and published by Frontiers Media SA. This book was released on 2021-11-09 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Beyond the Molecular Frontier written by National Research Council and published by National Academies Press. This book was released on 2003-03-19 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemistry and chemical engineering have changed significantly in the last decade. They have broadened their scopeâ€"into biology, nanotechnology, materials science, computation, and advanced methods of process systems engineering and controlâ€"so much that the programs in most chemistry and chemical engineering departments now barely resemble the classical notion of chemistry. Beyond the Molecular Frontier brings together research, discovery, and invention across the entire spectrum of the chemical sciencesâ€"from fundamental, molecular-level chemistry to large-scale chemical processing technology. This reflects the way the field has evolved, the synergy at universities between research and education in chemistry and chemical engineering, and the way chemists and chemical engineers work together in industry. The astonishing developments in science and engineering during the 20th century have made it possible to dream of new goals that might previously have been considered unthinkable. This book identifies the key opportunities and challenges for the chemical sciences, from basic research to societal needs and from terrorism defense to environmental protection, and it looks at the ways in which chemists and chemical engineers can work together to contribute to an improved future.
Download or read book Chirality in Drug Design and Development written by Indra K. Reddy and published by CRC Press. This book was released on 2004-03-15 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covering every essential element in the development of chiral products, this reference provides a solid overview of the formulation, biopharmaceutical characteristics, and regulatory issues impacting the production of these pharmaceuticals. It supports researchers as they evaluate the pharmacodynamic, pharmacokinetic, and toxicological characteristics of specific enantiomers and chiral drug compounds and addresses in one convenient reference all the major challenges pertaining to drug chirality that have been neglected in the literature. Chirality in Drug Design and Development collects the latest studies from an interdisciplinary team of experts on chiral drug design.
Download or read book The Organic Chemistry of Drug Synthesis Volume 7 written by Daniel Lednicer and published by John Wiley & Sons. This book was released on 2007-12-14 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The classic reference on the synthesis of medicinal agents -- now completely updated The seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of Volume 6. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered. As in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. The Organic Chemistry of Drug Synthesis, Volume 7 is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.
Download or read book The Way of Synthesis written by Tomas Hudlicky and published by Wiley-VCH. This book was released on 2007-09-04 with total page 1032 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds. With its attractive layout highlighting key parts and tactics using a second color, this is a useful tool for organic chemists, lecturers and students in chemistry, as well as those working in the chemical industry. "I think, as will many organic chemists, that the Hudlicky book will be the Bible of synthetic organic chemistry, the past, the present and the future. A hallmark publication." (Victor Snieckus)
Download or read book Electrogenerated Chemiluminescence written by Allen J. Bard and published by CRC Press. This book was released on 2004-07-20 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first source on this expanding analytical science, this reference explores advances in the instrumentation, design, and application of techniques with electrogenerated chemiluminescence (ECL), examining the use and impact of ECL-based assays in clinical diagnostics, life science research, environmental testing, food and water evaluation, and th
Download or read book Computer Sound Design written by Eduardo Miranda and published by Taylor & Francis. This book was released on 2012-10-12 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive introduction to software synthesis techniques and programming is intended for students, researchers, musicians, sound artists and enthusiasts in the field of music technology. The art of sound synthesis is as important for the electronic musician as the art of orchestration is important for symphonic music composers. Those who wish to create their own virtual orchestra of electronic instruments and produce original sounds will find this book invaluable. It examines a variety of synthesis techniques and illustrates how to turn a personal computer into a powerful and flexible sound synthesiser. The book also discusses a number of ongoing developments that may play an important role in the future of electronic music making. Previously published as Computer Sound Synthesis for the Electronic Musician, this second edition features a foreword by Jean-Claude Risset and provides new information on: · the latest directions in digital sound representation · advances in physical modelling techniques · granular and pulsar synthesis · PSOLA technique · humanoid voice synthesis · artificial intelligence · evolutionary computing The accompanying CD-ROM contains examples, complementary tutorials and a number of synthesis systems for PC and Macintosh platforms, ranging from low level synthesis programming languages to graphic front-ends for instrument and sound design. These include fully working packages, demonstration versions of commercial software and experimental programs from top research centres in Europe, North and South America.
Download or read book Graphene Oxide written by Wei Gao and published by Springer. This book was released on 2015-05-28 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on a group of new materials labeled "graphene oxides." It provides a comprehensive overview of graphene oxide-based nanomaterials in terms of their synthesis, structures, properties, and extensive applications in catalysis, separation, filtration, energy storage and conversion. The book also covers emerging research on graphite oxides and the impact of the research on fundamental and applied sciences.
Download or read book Metals in Medicine written by James C. Dabrowiak and published by John Wiley & Sons. This book was released on 2017-05-02 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: Working from basic chemical principles, Metals in Medicine, 2nd Edition describes a wide range of metal-based agents for treating and diagnosing disease. Thoroughly revised and restructured to reflect significant research activity and advances, this new edition contains extensive updates and new pedagogical features while retaining the popular feature boxes and end-of-chapter problems of the first edition. Topics include: Metallo-Drugs and their action Platinum drugs for treating cancer Anticancer agents beyond cisplatin including ruthenium, gold, titanium and gallium Responsive Metal Complexes Treating arthritis and diabetes with metal complexes Metal complexes for killing bacteria, parasites and viruses Metal ion imbalance and its links to diseases including Alzheimer's, Wilson's and Menkes disease Metal complexes for detecting disease Nanotechnology in medicine Now in full colour, Metals in Medicine, 2nd Edition employs real-life applications and chapter-end summaries alongside feature boxes and problems. It provides a complete and methodical examination of the use of metal complexes in medicine for advanced undergraduate and postgraduate students in medicinal inorganic chemistry, bioinorganic chemistry, biochemistry, pharmacology, biophysics, biology and bioengineering. It is also an invaluable resource for academic researchers and industrial scientists in inorganic chemistry, medicinal chemistry and drug development.
Download or read book Digital Frequency Synthesis Demystified written by Bar-Giora Goldberg and published by Elsevier. This book was released on 2000-02-20 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: · In-depth coverage of modern digital implementations of frequency synthesis architectures· Numerous design examples drawn from actual engineering projectsDigital frequency synthesis is used in modern wireless and communications technologies such as radar, cellular telephony, satellite communications, electronic imaging, and spectroscopy. This is book is a comprehensive overview of digital frequency synthesis theory and applications, with a particular emphasis on the latest approaches using fractional-N phase-locked loop technology. In-depth coverage of modern digital implementations of frequency synthesis architectures Numerous design examples drawn from actual engineering projects
Download or read book High Energy Density Fuels for Advanced Propulsion written by Ji-Jun Zou and published by John Wiley & Sons. This book was released on 2020-11-09 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book comprehensively and systematically demonstrates the theory and practice of designing, synthesizing and improving the performance of fuels. The contents range from polycyoalkane fuels, strained fuels, alky-diamondoid fuels, hypergolic and nanofluid fuels derived from fossil and biomass. All the chapters together clearly describe the important aspects of high-energy-density fuels including molecular design, synthesis route, physiochemical properties, and their application in improving the aerocraft performance. Vivid schematics and illustrations throughout the book enhance the accessibility to the relevant theory and technologies. This book provides the readers with fundamentals on high-energy-density fuels and their potential in advanced aerospace propulsion, and also provides the readers with inspiration for new development of advanced aerospace fuels.
Download or read book Design Fabrication and Characterization of Multifunctional Nanomaterials written by Sabu Thomas and published by Elsevier. This book was released on 2021-11-24 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Design, Fabrication, and Characterization of Multifunctional Nanomaterials covers major techniques for the design, synthesis, and development of multifunctional nanomaterials. The chapters highlight the main characterization techniques, including X-ray diffraction, scanning electron microscopy, high-resolution transmission electron microscopy, energy dispersive X-ray spectroscopy, and scanning probe microscopy.The book explores major synthesis methods and functional studies, including: - Brillouin spectroscopy; - Temperature-dependent Raman spectroscopic studies; - Magnetic, ferroelectric, and magneto-electric coupling analysis; - Organ-on-a-chip methods for testing nanomaterials; - Magnetron sputtering techniques; - Pulsed laser deposition techniques; - Positron annihilation spectroscopy to prove defects in nanomaterials; - Electroanalytic techniques. This is an important reference source for materials science students, scientists, and engineers who are looking to increase their understanding of design and fabrication techniques for a range of multifunctional nanomaterials. - Explains the major design and fabrication techniques and processes for a range of multifunctional nanomaterials; - Demonstrates the design and development of magnetic, ferroelectric, multiferroic, and carbon nanomaterials for electronic applications, energy generation, and storage; - Green synthesis techniques and the development of nanofibers and thin films are also emphasized.
Download or read book Bibliography of Mass Spectroscopy Literature for 1970 written by and published by . This book was released on 1972 with total page 900 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Interdisciplinary Design Proceedings of the 21st CIRP Design Conference written by and published by Mary Kathryn Thompson. This book was released on with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt:
