Download or read book The Family Gene written by Joselin Linder and published by HarperCollins. This book was released on 2017-03-14 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: A riveting medical mystery about a young woman’s quest to uncover the truth about her likely fatal genetic disorder that opens a window onto the exploding field of genomic medicine When Joselin Linder was in her twenties her legs suddenly started to swell. After years of misdiagnoses, doctors discovered a deadly blockage in her liver. Struggling to find an explanation for her unusual condition, Joselin compared the medical chart of her father—who had died from a mysterious disease, ten years prior—with that of an uncle who had died under similarly strange circumstances. Delving further into the past, she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly, this was more than a fluke. Setting out to build a more complete picture of the illness that haunted her family, Joselin approached Dr. Christine Seidman, the head of a group of world-class genetic researchers at Harvard Medical School, for help. Dr. Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something called a private mutation—meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation. Here, Joselin tells the story of their gene: the lives it claimed and the future of genomic medicine with the potential to save those that remain. Digging into family records and medical history, conducting interviews with relatives and friends, and reflecting on her own experiences with the Harvard doctor, Joselin pieces together the lineage of this deadly gene to write a gripping and unforgettable exploration of family, history, and love. A compelling chronicle of survival and perseverance, The Family Gene is an important story of a young woman reckoning with her father’s death, her own mortality, and her ethical obligations to herself and those closest to her.
Download or read book Deadly Genes written by Warren Murphy and published by Bloomsbury Publishing. This book was released on 2023-11-16 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Meet the Boss Camelus-Whitus, affectionately known as BBQ to the genetic engineers at Boston Bio. Brainchild of the beautiful but sociopathic Dr. Judith White, this homely, sad-eyed creature is a bio-masterpiece of gene splicing, and billed as the world’s most promising new food source. A bungled kidnapping of the BBQ by animal rights activists results in the unfortunate discovery that these slow, silly-looking creatures might actually be bloodthirsty killers. Vicious man-eaters or docile darlings? Chiun wants one for a pet and Remo’s getting really bad vibes about the sinister secrets behind the whole BBQ thing, especially when he’s been selected as the prime stud material in a madwoman’s brilliant plot to send the human race out to lunch... permanently. Breathlessly action-packed and boasting a winning combination of thrills, humour and mysticism, the Destroyer is one of the bestselling series of all time.
Download or read book The Genetic Inferno written by and published by Cambridge University Press. This book was released on 2000-09-07 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating account of the quest to understand the biological basis of human behavior.
Download or read book Human Prion Diseases written by and published by Elsevier. This book was released on 2018-06-07 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems. Offers an authoritative overview of prion diseases in humans, detailing the pathogenesis of the disease, clinical investigations, and the diagnosis of both the genetic and acquired forms Provides clarity and context by presenting prion diseases in relation to other neurodegenerative diseases in humans Emphasizes the unique properties of prion diseases and consequent problems they can cause, both clinically and in public health terms
Download or read book Heritable Human Genome Editing written by The Royal Society and published by National Academies Press. This book was released on 2021-01-16 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Download or read book Health Effects of Exposure to Low Levels of Ionizing Radiation written by National Research Council and published by National Academies. This book was released on 1990-02-01 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reevaluates the health risks of ionizing radiation in light of data that have become available since the 1980 report on this subject was published. The data include new, much more reliable dose estimates for the A-bomb survivors, the results of an additional 14 years of follow-up of the survivors for cancer mortality, recent results of follow-up studies of persons irradiated for medical purposes, and results of relevant experiments with laboratory animals and cultured cells. It analyzes the data in terms of risk estimates for specific organs in relation to dose and time after exposure, and compares radiation effects between Japanese and Western populations.
Download or read book Fatal Invention written by Dorothy Roberts and published by New Press/ORIM. This book was released on 2011-06-14 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: An incisive, groundbreaking book that examines how a biological concept of race is a myth that promotes inequality in a supposedly “post-racial” era. Though the Human Genome Project proved that human beings are not naturally divided by race, the emerging fields of personalized medicine, reproductive technologies, genetic genealogy, and DNA databanks are attempting to resuscitate race as a biological category written in our genes. This groundbreaking book by legal scholar and social critic Dorothy Roberts examines how the myth of race as a biological concept—revived by purportedly cutting-edge science, race-specific drugs, genetic testing, and DNA databases—continues to undermine a just society and promote inequality in a supposedly “post-racial” era. Named one of the ten best black nonfiction books 2011 by AFRO.com, Fatal Invention offers a timely and “provocative analysis” (Nature) of race, science, and politics that “is consistently lucid . . . alarming but not alarmist, controversial but evidential, impassioned but rational” (Publishers Weekly, starred review). “Everyone concerned about social justice in America should read this powerful book.” —Anthony D. Romero, executive director, American Civil Liberties Union “A terribly important book on how the ‘fatal invention’ has terrifying effects in the post-genomic, ‘post-racial’ era.” —Eduardo Bonilla-Silva, professor of sociology, Duke University, and author of Racism Without Racists: Color-Blind Racism and the Persistence of Racial Inequality in the United States “Fatal Invention is a triumph! Race has always been an ill-defined amalgam of medical and cultural bias, thinly overlaid with the trappings of contemporary scientific thought. And no one has peeled back the layers of assumption and deception as lucidly as Dorothy Roberts.” —Harriet A. Washington, author of and Deadly Monopolies: The Shocking Corporate Takeover of Life Itself
Download or read book Deadly Monopolies written by Harriet A. Washington and published by Anchor. This book was released on 2012-11-13 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the award-winning author of Medical Apartheid, an exposé of the rush to own and exploit the raw materials of life—including yours. Think your body is your own to control and dispose of as you wish? Think again. The United States Patent Office has granted at least 40,000 patents on genes controlling the most basic processes of human life, and more are pending. If you undergo surgery in many hospitals you must sign away ownership rights to your excised tissues, even if they turn out to have medical and fiscal value. Life itself is rapidly becoming a wholly owned subsidiary of the medical-industrial complex. Deadly Monopolies is a powerful, disturbing, and deeply researched book that illuminates this “life patent” gold rush and its harmful, and even lethal, consequences for public health. Like the bestselling The Immortal Life of Henrietta Lacks, it reveals in shocking detail just how far the profit motive has encroached in colonizing human life and compromising medical ethics.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Deadly Truth written by Gerald N. Grob and published by Harvard University Press. This book was released on 2009-07 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Deadly Truth chronicles the complex interactions between disease and the peoples of America from the pre-Columbian world to the present. Grob's ultimate lesson is stark but valuable: there can be no final victory over disease. The world in which we live undergoes constant change, which in turn creates novel risks to human health and life. We conquer particular diseases, but others always arise in their stead. In a powerful challenge to our tendency to see disease as unnatural and its virtual elimination as a real possibility, Grob asserts the undeniable biological persistence of disease. Diseases ranging from malaria to cancer have shaped the social landscape--sometimes through brief, furious outbreaks, and at other times through gradual occurrence, control, and recurrence. Grob integrates statistical data with particular peoples and places while giving us the larger patterns of the ebb and flow of disease over centuries. Throughout, we see how much of our history, culture, and nation-building was determined--in ways we often don't realize--by the environment and the diseases it fostered. The way in which we live has shaped, and will continue to shape, the diseases from which we get sick and die. By accepting the presence of disease and understanding the way in which it has physically interacted with people and places in past eras, Grob illuminates the extraordinarily complex forces that shape our morbidity and mortality patterns and provides a realistic appreciation of the individual, social, environmental, and biological determinants of human health.
Download or read book Your Genes Your Choices written by Catherine Baker and published by . This book was released on 1996 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Program discusses the Human Genome Project, the science behind it, and the ethical, legal and social issues raised by the project.
Download or read book Social Mendelism written by Amir Teicher and published by Cambridge University Press. This book was released on 2020-02-13 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Will revolutionize reader's understanding of the principles of modern genetics, Nazi racial policies and the relationship between them.
Download or read book Lethal Genes written by Linda Grant and published by Scribner Book Company. This book was released on 1996 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: In San Francisco, PI Catherine Sayler investigates sabotage in a university's agricultural laboratory. Someone is killing researchers working on better ways to grow corn. Suspects include a competing biotechnical firm. By the author of A Woman's Place.
Download or read book Genome written by Matt Ridley and published by Harper Collins. This book was released on 2013-03-26 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Ridley leaps from chromosome to chromosome in a handy summation of our ever increasing understanding of the roles that genes play in disease, behavior, sexual differences, and even intelligence. . . . . He addresses not only the ethical quandaries faced by contemporary scientists but the reductionist danger in equating inheritability with inevitability.” — The New Yorker The genome's been mapped. But what does it mean? Matt Ridley’s Genome is the book that explains it all: what it is, how it works, and what it portends for the future Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.
Download or read book Management of Genetic Syndromes written by Suzanne B. Cassidy and published by John Wiley & Sons. This book was released on 2011-09-20 with total page 1678 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bestselling guide to the medical management of common genetic syndromes —now fully revised and expanded A review in the American Journal of Medical Genetics heralded the first edition of Management of Genetic Syndromes as an "unparalleled collection of knowledge." Since publication of the first edition, improvements in the molecular diagnostic testing of genetic conditions have greatly facilitated the identification of affected individuals. This thorough revision of the critically acclaimed bestseller offers original insights into the medical management of sixty common genetic syndromes seen in children and adults, and incorporates new research findings and the latest advances in diagnosis and treatment of these disorders. Expanded to cover five new syndromes, this comprehensive new edition also features updates of chapters from the previous editions. Each chapter is written by an expert with extensive direct professional experience with that disorder and incorporates thoroughly updated material on new genetic findings, consensus diagnostic criteria, and management strategies. Edited by two of the field's most highly esteemed experts, this landmark volume provides: A precise reference of the physical manifestations of common genetic syndromes, clearly written for professionals and families Extensive updates, particularly in sections on diagnostic criteria and diagnostic testing, pathogenesis, and management A tried-and-tested, user-friendly format, with each chapter including information on incidence, etiology and pathogenesis, diagnostic criteria and testing, and differential diagnosis Up-to-date and well-written summaries of the manifestations followed by comprehensive management guidelines, with specific advice on evaluation and treatment for each system affected, including references to original studies and reviews A list of family support organizations and resources for professionals and families Management of Genetic Syndromes, Third Edition is a premier source to guide family physicians, pediatricians, internists, medical geneticists, and genetic counselors in the clinical evaluation and treatment of syndromes. It is also the reference of choice for ancillary health professionals, educators, and families of affected individuals looking to understand appropriate guidelines for the management of these disorders. From a review of the first edition: "An unparalleled collection of knowledge . . . unique, offering a gold mine of information." —American Journal of Medical Genetics
Download or read book A Lethal Inheritance written by Victoria Costello and published by Prometheus Books. This book was released on 2012-01-10 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every family has secrets; only some secrets are lethal. In Victoria Costello’s family mental illness had been given many names over at least four generations until this inherited conspiracy of silence finally endangered the youngest members of the family, her children. In this riveting story—part memoir, detective story, and scientific investigation—the author recounts how the mental unraveling of her seventeen-year-old son Alex compelled her to look back into family history for clues to his condition. Eventually she tied Alex’s descent into hallucinations and months of shoeless wandering on the streets of Los Angeles to his great grandfather’s suicide on a New York City railroad track in 1913. But this insight brought no quick relief. Within two years of Alex’s diagnosis of paranoid schizophrenia, both she and her youngest son succumbed to two different mental disorders: major depression and anxiety disorder. Costello depicts her struggle to get the best possible mental health care for her sons and herself, treatment that ultimately brings each of them to full recovery. In the process, she discovers new science that explains how clusters of mental illness traverse family generations. Artfully weaving the scientific into the personal, Costello takes a journey to the far reaches of neuroscience and reports back on the startling findings it is yielding about the complex interplay between genes and environment that drives mental illness, and what it now tells us about how parents can trump a lethal inheritance. She shares the results of long-term U.K. and European family studies identifying the earliest signs of mental illnesses that can be passed on from grandparents to parents and grandchildren. She tracks ongoing clinical trials to reverse the courses of these diseases through early intervention with the latest evidence-based treatments and offers brain-healthy choices individuals and families can make to prevent mental illness—freeing future generations to live healthier, happier lives.
Download or read book Deadly Companions written by Dorothy H. Crawford and published by Oxford University Press. This book was released on 2009 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ever since we started huddling together in communities, the story of human history has been inextricably entwined with the story of microbes. They have evolved and spread amongst us, shaping our culture through infection, disease, and pandemic. At the same time, our changing human culture has itself influenced the evolutionary path of microbes. Dorothy H. Crawford here shows that one cannot be truly understood without the other. Beginning with a dramatic account of the SARS pandemic at the start of the 21st century, she takes us back in time to follow the interlinked history of microbes and man, taking an up-to-date look at ancient plagues and epidemics, and identifying key changes in the way humans have lived - such as our move from hunter-gatherer to farmer to city-dweller - which made us vulnerable to microbe attack. Showing how we live our lives today - with increasing crowding and air travel - puts us once again at risk, Crawford asks whether we might ever conquer microbes completely, or whether we need to take a more microbe-centric view of the world. Among the possible answers, one thing becomes clear: that for generations to come, our deadly companions will continue to shape human history.
