Download or read book Dark Art of Blood Cultures written by Wm. Michael Dunne, Jr. and published by John Wiley & Sons. This book was released on 2020-07-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the clinical microbiology laboratory, blood is a critical diagnostic sample that, in the majority of cases is sterile (or is it?). However, when microbes gain access to and multiply in the bloodstream, it can result in life-threatening illness including sepsis. Mortality rates from bloodstream infection and sepsis range from 25% to 80%, killing millions of people annually. Blood cultures are a vital technology used in the microbiology laboratory to isolate and identify microbes and predict their response to antimicrobial therapy. The Dark Art of Blood Cultures, edited by Wm. Michael Dunne, Jr., and Carey-Ann D. Burnham, surveys the entire field of blood culture technology, providing valuable information about every phase of the process, from drawing samples to culture methods to processing positive cultures. The Dark Art of Blood Cultures is organized around several major topics. History of blood culture methods. Details the timeline of blood culture methods from manual through automated and describes the technological development of the leading automated blood culture systems (Bactec, BacT/Alert, and VersaTREK). Manual and automated blood culture methods. Critiques manual and automated methods for setting up blood cultures for adult and pediatric patients. Detection of pathogens directly from blood specimens. Describes currently available CE marked and FDA-cleared commercial tests using both phenotypic and genotypic markers, including their strengths and limitations. The workflow of culturing blood. Includes best practices from specimen collection to culture system verification, processing positive cultures for microbe identification and antibiotic susceptibility determination, along with the epidemiology of positive blood cultures and the value of postmortem blood cultures. Microorganisms in the blood. Examines the concept of a blood microbiome in healthy and diseased individuals. The Dark Art of Blood Cultures is a resource that clinicians, laboratorians, lab directors, and hospital administrators will find engaging and extremely useful. If you are looking for online access to the latest clinical microbiology content, please visit www.wiley.com/learn/clinmicronow.

Download or read book Clinical Microbiology Procedures Handbook Multi Volume written by Amy L. Leber and published by John Wiley & Sons. This book was released on 2024-11-13 with total page 6587 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gold Standard consensus-based procedures from the experts. The Clinical Microbiology Procedures Handbook, 5th edition, provides those engaged in microbial analysis of clinical specimens with procedures for the detection, identification, and characterization of microorganisms involved in human infections. This unique and valuable collection of step-by-step descriptions of the numerous testing modalities used in the clinical microbiology laboratory was written and edited by highly knowledgeable laboratorians. The 5th edition features two new sections, one on blood cultures and one on MALDI-TOF MS, and the sections on molecular diagnostics, virology, and serology were extensively revised and updated. Presented over multiple volumes, this handbook enables laboratory staff to perform all analyses, including appropriate quality control recommendations, from the receipt of the specimen through processing, testing, interpretation, presentation of the final report, and subsequent consultation. If you are looking for online access to the latest from this reference or site access for your lab, please visit www.wiley.com/learn/clinmicronow.

Download or read book Blood Rush written by Jan Verplaetse and published by Reaktion Books. This book was released on 2020-03-16 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a young man, Jan Verplaetse saw a hare suspended from a meat hook, skinned and gutted. What struck him so forcefully at the time was not the animal itself, but the blood gently dripping from its mouth. His reaction prompted the start of a quest he undertakes in this book: to investigate our fascination with blood, the most vital of fluids. Blood Rush shows how, throughout history, blood has had the capacity to intoxicate us, to the point that we lose ourselves, whether in violence, through hunting, fighting, or killing, or in the vicarious thrill of watching sporting events, horror films, or video games. Are these feelings physical, or in our imagination? Where does the magic of blood come from? In his deeply researched and provocative narrative, Verplaetse moves from antiquity to the present, from magic to experimental psychology, from philosophy to religion and scientific discoveries, to demonstrate why blood at once attracts and repels us.

Download or read book Art in the Blood A Sherlock Holmes Adventure Book 1 written by Bonnie MacBird and published by HarperCollins UK. This book was released on 2015-08-27 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: London. A snowy December, 1888. Sherlock Holmes, 34, is languishing and back on cocaine after a disastrous Ripper investigation. Watson can neither comfort nor rouse his friend – until a strangely encoded letter arrives from Paris.

Download or read book Color Atlas of Medical Bacteriology written by Luis M. de la Maza and published by John Wiley & Sons. This book was released on 2020-07-15 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique visual reference presents more than 750 brilliant, four-color images of bacterial isolates commonly encountered in diagnostic microbiology and the methods used to identify them, including microscopic and phenotypic characteristics, colony morphology, and biochemical properties. Chapters cover the most important bacterial pathogens and related organisms, including updated taxonomy, epidemiology, pathogenicity, laboratory and antibiotic susceptibility testing, and molecular biology methodology Tables summarize and compare key biochemical reactions and other significant characteristics New to this edition is a separate chapter covering the latest developments in total laboratory automation The comprehensive chapter on stains, media, and reagents is now augmented with histopathology images A new Fast Facts chapter presents tables that summarize and illustrate the most significant details for some of the more commonly encountered organisms For the first time, this easy-to-use atlas is available digitally for enhanced searching. Color Atlas of Medical Bacteriology remains the most valuable illustrative supplement for lectures and laboratory presentations, as well as for laboratorians, clinicians, students, and anyone interested in diagnostic medical bacteriology.

Download or read book Blood Dark written by Louis Guilloux and published by New York Review of Books. This book was released on 2017-10-17 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Set during World War I, this monumental philosophical novel about human despair inspired Albert Camus' own writing and prefigured the greater existential movement. Blood Dark tells the story of a brilliant philosopher trapped in a provincial town and of his spiraling descent into self-destruction. Cripure, as his students call him—the name a mocking contraction of Critique of Pure Reason—despises his colleagues, despairs of his charges, and is at odds with his family. The year is 1917, and the slaughter of the First World War goes on and on, with French soldiers not only dying in droves but also beginning to rise up in protest. Still haunted by the memory of the wife who left him long ago, Cripure turns his fury and scathing wit on everyone around him. Before he knows it, a trivial dispute with a complacently patriotic colleague has embroiled him in a duel.

Download or read book Antisepsis Disinfection and Sterilization written by Gerald E. McDonnell and published by John Wiley & Sons. This book was released on 2020-07-10 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance, by Gerald E. McDonnell, is a detailed and accessible presentation of the current methods of microbial control. Each major category, such as physical disinfection methods, is given a chapter, in which theory, spectrum of activity, advantages, disadvantages, and modes of action of the methods are thoroughly and clearly presented. Sufficient background on the life cycles and general anatomy of microorganisms is provided so that the reader who is new to microbiology will better appreciate how physical and chemical biocides work their magic on microbes. Other topics in the book include: Evaluating the efficacy of chemical antiseptics and disinfectants, and of physical methods of microbial control and sterilization. Understanding how to choose the proper biocidal product and process for specific applications. Classic physical and chemical disinfection methods, such as heat, cold, non-ionizing radiation, acids, oxidizing agents, and metals. Newer chemical disinfectants, including, isothiazolones, micro-and nano-particles, and bacteriophages as control agents. Antisepsis of skin and wounds and the biocides that can be used as antiseptics. Classic methods of physical sterilization, such as, moist heat and dry heat sterilization, ionizing radiation, and filtration, along with newer methods, including, the use of plasma or pulsed light. Chemical sterilization methods that use ethylene oxide, formaldehyde, or a variety of other oxidizing agents. A detailed look at the modes of action of biocides in controlling microbial growth and disrupting microbial physiology. Mechanisms that microorganisms use to resist the effects of biocides. The second edition of Antisepsis, Disinfection, and Sterilization: Types, Action, and Resistance is well suited as a textbook and is outstanding as a reference book for facilities managers and application engineers in manufacturing plants, hospitals, and food production facilities. It is also essential for public health officials, healthcare professionals, and infection control practitioners.

Download or read book Dark Banquet written by Bill Schutt and published by Crown. This book was released on 2009-10-06 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A witty, scientifically accurate, and often intensely creepy exploration of sanguivorous creatures.”—San Francisco Chronicle “Bill Schutt turns whatever fear and disgust you may feel towards nature’s vampires into a healthy respect for evolution’s power to fill every conceivable niche.”—Carl Zimmer, author of Parasite Rex and Microcosm: E. coli and the New Science of Life For centuries, blood feeders have inhabited our nightmares and horror stories, as well as the shadowy realms of scientific knowledge. In Dark Banquet, zoologist Bill Schutt takes us on a fascinating voyage into the world of some of nature’s strangest creatures—the sanguivores. Using a sharp eye and mordant wit, Schutt makes a remarkably persuasive case that blood feeders, from bats to bedbugs, are as deserving of our curiosity as warmer and fuzzier species are—and that many of them are even worthy of conservation. Examining the substance that sustains nature’s vampires, Schutt reveals just how little we actually knew about blood until well into the twentieth century. We revisit George Washington on his deathbed to learn how ideas about blood and the supposedly therapeutic value of bloodletting, first devised by the ancient Egyptians and Greeks, survived into relatively modern times. Dark Banquet details our dangerous and sometimes deadly encounters with ticks, chiggers, and mites (the ­latter implicated in Colony Collapse Disorder—currently devastating honey bees worldwide). Then there are the truly weird—vampire finches. And if you thought piranha were scary, some people believe that the candiru (or willy fish) is the best reason to avoid swimming in the Amazon. Enlightening and alarming, Dark Banquet peers into a part of the natural world to which we are, through our blood, inextricably linked.

Download or read book At Night All Blood Is Black written by David Diop and published by Farrar, Straus and Giroux. This book was released on 2020-11-10 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: *WINNER OF THE 2021 INTERNATIONAL BOOKER PRIZE* *ONE OF PRESIDENT BARACK OBAMA'S FAVORITE BOOKS OF 2021* Winner of the Los Angeles Times Book Prize for fiction Shortlisted for the 2022 DUBLIN Literary Award "Astonishingly good." —Lily Meyer, NPR "So incantatory and visceral I don’t think I’ll ever forget it." —Ali Smith, The Guardian | Best Books of 2020 One of The Wall Street Journal's 11 best books of the fall | One of The A.V. Club's fifteen best books of 2020 |A Sunday Times best book of the year Selected by students across France to win the Prix Goncourt des Lycéens, David Diop’s English-language, historical fiction debut At Night All Blood is Black is a “powerful, hypnotic, and dark novel” (Livres Hebdo) of terror and transformation in the trenches of the First World War. Alfa Ndiaye is a Senegalese man who, never before having left his village, finds himself fighting as a so-called “Chocolat” soldier with the French army during World War I. When his friend Mademba Diop, in the same regiment, is seriously injured in battle, Diop begs Alfa to kill him and spare him the pain of a long and agonizing death in No Man’s Land. Unable to commit this mercy killing, madness creeps into Alfa’s mind as he comes to see this refusal as a cruel moment of cowardice. Anxious to avenge the death of his friend and find forgiveness for himself, he begins a macabre ritual: every night he sneaks across enemy lines to find and murder a blue-eyed German soldier, and every night he returns to base, unharmed, with the German’s severed hand. At first his comrades look at Alfa’s deeds with admiration, but soon rumors begin to circulate that this super soldier isn’t a hero, but a sorcerer, a soul-eater. Plans are hatched to get Alfa away from the front, and to separate him from his growing collection of hands, but how does one reason with a demon, and how far will Alfa go to make amends to his dead friend? Peppered with bullets and black magic, this remarkable novel fills in a forgotten chapter in the history of World War I. Blending oral storytelling traditions with the gritty, day-to-day, journalistic horror of life in the trenches, David Diop's At Night All Blood is Black is a dazzling tale of a man’s descent into madness.

Download or read book Scientific Integrity written by Francis L. Macrina and published by John Wiley & Sons. This book was released on 2014-07-22 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This widely adopted textbook provides the essential content and skill-building tools for teaching the responsible conduct of scientific research. Scientific Integrity covers the breadth of concerns faced by scientists: protection of animal and human experimental subjects, scientific publication, intellectual property, conflict of interest, collaboration, record keeping, mentoring, and the social and ethical responsibilities of scientists. Learning activities and resources designed to elucidate the principles of Scientific Integrity include Dozens of highly relevant, interactive case studies for discussion in class or online Numerous print and online resources covering the newest research guidelines, regulations, mandates and policies Discussion questions, role-playing exercises, and survey tools to promote critical thought Documents including published rules of conduct, sample experimentation protocols, and patent applications The new edition of Scientific Integrity responds to significant recent changes—new mandates, policies, laws, and other developments—in the field of responsible conduct of research. Dr. Macrina plants the seeds of awareness of existing, changing, and emerging standards in scientific conduct and provides the tools to promote critical thinking in the use of that information. Scientific Integrity is the original turnkey text to guide the next generations of scientists as well as practicing researchers in the essential skills and approaches for the responsible conduct of science.

Download or read book Pediatric Diagnostic Labs for Primary Care An Evidence based Approach written by Rita Marie John and published by Springer Nature. This book was released on 2022-04-27 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook helps nurses, physician assistants, medical students and residents to order appropriate tests and understand how to interpret them to improve their diagnostic reasoning. Children are not like adults, and interpreting of the results of their diagnostic laboratory tests requires knowledge of the biochemical and metabolic differences. Using a combination of information, questions and case studies, the book allows readers to gain an understanding of the key concepts of sensitivity, specificity, and positive and negative predictive values, as well as the indications for diagnostic lab tests. This textbook presents the state of art in testing across body systems and guidance on how to order and interpret diagnostic laboratory tests in pediatric patients. Each chapter includes learning objectives, tables and figures, as well as questions and references for further learning. This textbook provides an update for clinicians and is a valuable learning tool for students and new clinicians. .

Download or read book Oral Microbiology and Immunology written by Richard J. Lamont and published by John Wiley & Sons. This book was released on 2020-08-06 with total page 595 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral Microbiology and Immunology, Third Edition The field of oral microbiology has seen fundamental conceptual changes in recent years. Microbial communities are now seen as the fundamental etiological agent in oral diseases through their interface with host inflammatory responses. Study of structured microbial communities has increased our understanding of the roles of each member in the pathogenesis of oral diseases, principles that apply to both periodontitis and dental caries. Against this backdrop, the third edition of Oral Microbiology and Immunology has been substantially expanded and rewritten by an international team of authors and editors. Featured in the current edition are: links between oral infections and systemic disease revised and updated overview of the role of the immune system in oral infections thorough discussions of biofilm development and control more extensive illustrations and Key Points for student understanding Graduate students, researchers, and clinicians as well as students will find this new edition valuable in study and practice. The field of oral microbiology has seen fundamental conceptual changes in recent years. Microbial communities are now seen as the fundamental etiological agent in oral diseases through their interface with host inflammatory responses. Study of structured microbial communities has increased our understanding of the roles of each member in the pathogenesis of oral diseases, principles that apply to both periodontitis and dental caries.

Download or read book A Dark Inheritance written by Brooke N. Newman and published by Yale University Press. This book was released on 2018-08-28 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major reassessment of the development of race and subjecthood in the British Atlantic Focusing on Jamaica, Britain’s most valuable colony in the Americas by the mid-eighteenth century, this book explores the relationship between racial classifications and the inherited rights and privileges associated with British subject status. Brooke Newman reveals the centrality of notions of blood and blood mixture to evolving racial definitions and sexual practices in colonial Jamaica and to legal and political debates over slavery and the rights of imperial subjects on both sides of the Atlantic. Weaving together a diverse range of sources, Newman shows how colonial racial ideologies rooted in fictions of blood ancestry at once justified permanent, hereditary slavery for Africans and barred members of certain marginalized groups from laying claim to British liberties on the basis of hereditary status. This groundbreaking study demonstrates that challenges to an Atlantic slave system underpinned by distinctions of blood had far-reaching consequences for British understandings of race, gender, and national belonging.

Download or read book Zoonoses written by Rolf Bauerfeind and published by John Wiley & Sons. This book was released on 2015-12-22 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zoonoses are a persistent threat to the global human health Today, more than 200 diseases occurring in humans and animals are known to be mutually transmitted. Classical infectious diseases, such as rabies, plague, and yellow fever, have not been eradicated despite major efforts. New zoonotic diseases are on the increase due global conditions such as overpopulation, wars, and food scarcity, which facilitate human contact with rodents, stray animals, and their parasites. In addition, humans are unwittingly becoming accidental hosts and new links in an infectious chain by engaging in activities such as survival training, which involves camping in open areas and consumption of raw or insufficiently cooked food. Zoonotic infections cause a variety of symptoms that often do not provide clear evidence of a known disease. Zoonoses, Fourth Edition, describes most occurring worldwide zoonosis and facilitates the identification, diagnosis and treatment of zoonotic infections. Written by a team of doctors, medical microbiologists and veterinarians, this completely, revised edition covers all aspects of the epidemiology and prevention of zoonotic diseases through clear descriptions of various illnesses. Specifically, this fourth edition covers zoonosis caused by viruses, bacteria, fungi and parasites infections caused by animal bites infections and intoxications by animal foods Iatrogenic transmission of zoonotic pathogens Zoonoses is an indispensable reference for clinicians and laboratorians.

Download or read book By Darkness Hid written by Jill Williamson and published by Marcher Lord Press. This book was released on 2009-04 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Given the chance to train as a squire, kitchen servant Achan Cham hopes to pull himself out of his pitiful life and become a Kingsguard Knight. When Achan's owner learns of his training, he forces Achan to spar with the Crown Prince--more of a death sentence than an honor. Meanwhile, strange voices in Achan's head cause him to fear he's going mad. While escorting the prince to a council presentation, their convoy is attacked. Achan is wounded and arrested, but escapes from prison--only to discover a secret about himself he never believed possible.

Download or read book Cases in Medical Microbiology and Infectious Diseases written by Peter H. Gilligan and published by John Wiley & Sons. This book was released on 2014-08-01 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cases in Medical Microbiology and Infectious Diseases challenges students to develop a working knowledge of the variety of microorganisms that cause infections in humans. This valuable, interactive text will help them better understand the clinical importance of the basic science concepts presented in medical microbiology or infectious disease courses. The cases are presented as "unknowns" and represent actual case presentations of patients the authors have encountered. Each case is accompanied by several questions to test knowledge in four broad areas including the organism's characteristics and laboratory diagnosis; pathogenesis and clinical characteristics of the infection; epidemiology; and prevention and, in some cases, drug resistance and treatment. This new fourth edition includes: an entirely new section, "Advanced Cases," which includes newly recognized disease agents as well as highly complex cases where the interaction of the immune system and human pathogens can be more closely examined a revised "Primer on the Laboratory Diagnosis of Infectious Diseases" section that reflects the increasing importance of molecular-based assays Forty-two new cases that explore the myriad advances in the study of infectious disease in the past decade Thirty-two updated cases that reflect the current state of the art as it relates to the organism causing the infection This textbook also include specific tools to assist students in solving the cases, including a table of normal values, glossary of medical terms, and figures illustrating microscopic organism morphology, laboratory tests, and clinical symptoms. Cases in Medical Microbiology and Infectious Diseases is a proven resource for preparing for Part I of the National Board of Medical Examiners Exam and an excellent reference for infectious disease rotations.

Download or read book Antibiotics written by Christopher Walsh and published by John Wiley & Sons. This book was released on 2020-08-06 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions: What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed? Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.