Download or read book Cyclic Nucleotides in the Nervous System written by John Daly and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The elucidation of the cellular and molecular bases underlying the inte grated function of the central nervous system, both in disease and in health, must ultimately come from the combined efforts of scientists from many disciplines, including biology, chemistry, histology, pathology, physiology, pharmacology, and psychology. Communication between scientists from these various disciplines-vital to the advancement of our understanding of the function of the nervous system-has become more and more difficult in recent years. Both increasing specialization and the incredible increases in publications pertinent to brain research in a wide spectrum of journals, in symposium volumes, in monographs, in abstracts, and in reviews contrib ute to the problems of cross-communication and even of communication within a scientific discipline. Research on the significance of cyclic nucleo tides to the function of nervous systems is particularly illustrative of the communication problem. Since the initial publications by Sutherland, Rall, and Butcher in the late fifties and early sixties on high levels of adenylate cyclase, phosphodiesterases, and cyclic AMP in brain, the ensuing litera ture of this field has expanded exponentially. At the present time, from five to ten publications relevant to cyclic nucleotides and the nervous system appear each week. Indeed, these are minimal numbers based mainly on examination of literature titles and key index words. Many articles concerned with some aspect of central function contain, buried within their text, experiments with or related to cyclic nucleotides.
Download or read book Cyclic Nucleotides in the Nervous System written by George I. Drummond and published by New York : Raven Press. This book was released on 1984 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cyclic Nucleotides in the Nervous System written by George I. Drummond and published by . This book was released on 1984-01-01 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cyclic Nucleotide Phosphodiesterases in the Central Nervous System written by Nicholas J. Brandon and published by John Wiley & Sons. This book was released on 2014-03-07 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.
Download or read book Cyclic Nucleotides in the Central Nervous System written by Tamas Bartfai and published by . This book was released on 1978 with total page 3 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Role of Cyclic Nucleotides in Central Synaptic Function Renal Transport of Amino Acids written by Floyd E. Bloom and published by Springer-Verlag. This book was released on 2019-06-12 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cyclic Nucleotide Signaling written by Xiaodong Cheng and published by CRC Press. This book was released on 2015-05-07 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for laboratory use. Students and investigators new to the field will find this book particularly inform
Download or read book Cyclic Nucleotides Cyclic Nucleotide Phosphodiesterase Protein Kinase and Phosphoprotein Phosphatase in the Central Nervous System of Manduca Sexta written by Edward Elmo Albin and published by . This book was released on 1978 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cyclic Nucleotides Phosphorylated Proteins and Neuronal Function written by Paul Greengard and published by . This book was released on 1978 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Action of drugs on the cerebellar electrical activities written by G. Gogolák and published by . This book was released on 1980 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neurotransmitters Cyclic Nucleotides and Adenyl Cyclase in the Central Nervous System of Manduca Sexta written by Duncan Paul Taylor and published by . This book was released on 1977 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Minireviews of the Neurosciences written by Bernard B. Brodie and published by Elsevier. This book was released on 2013-09-03 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Minireviews of the Neurosciences from Life Sciences discusses the regulation of tryptophan and tyrosine hydroxylase. This book also addresses the neurochemical correlations of synaptically active amino acids. This book deals first with the role of calcium in the central effects of biogenic amines; neuroendocrinology of human sleep; factors in central serotonergic synapse regulation; noradrenergic mediation of traumatic spinal cord; role of cyclic nucleotides in visual excitation; and function and organization of chromaffin vesicle. Other chapters consider the analysis of nerve growth factor, the sympathetic regulation of thyroid hormone secretion, and the mechanism if trans-synaptic enzyme induction. A study of the functions of the catecholamines and acetylcholine in endocrine regulation is presented. The final chapters examine the effects of brain monoamines in male sexual behavior and the behavior of L-dopa in Parkinson’s disease. The book can provide useful information to neurologists, students, and researchers.
Download or read book The Role of 2 3 Cyclic Nucleotide 3 Phosphodiesterase CNP in the Peripheral Nervous System written by Theresa Kungl and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Effects of Psychoactive Drugs on Cyclic Nucleotides in the Central Nervous System written by Gene C. Palmer and published by . This book was released on 1983 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cyclic Nucleotides and Protein Phosphorylation in Cell Regulation written by E.-G. Krause and published by Elsevier. This book was released on 2014-05-18 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 54, Symposium S7: Cyclic Nucleotides and Protein Phosphorylation in Cell Regulation documents the proceedings of the 12th Federation of European Biochemical Societies (FEBS) Meeting held in Dresden, Germany on July 5-7, 1978. This book discusses the biological significance and biochemical aspects of cyclic nucleotides and protein phosphorylation in cell regulation. The general aspects of cyclic nucleotide metabolism and action; cyclic nucleotides and nervous system; and cyclic nucleotides in muscle tissues are also elaborated. This publication likewise covers the cyclic nucleotides in secretion processes and miscellaneous aspects of cyclic nucleotide-dependent and independent protein phosphorylation. This volume is valuable to biochemists and biologists concerned with the cyclic nucleotides and protein phosphorylation in cell regulation.
Download or read book Synaptic Modulators written by Leslie Iversen and published by Springer. This book was released on 1975-10-01 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modulators Mediators and Specifiers in Brain Function written by Y. H. Erlich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: While neuroanatomy and neurophysiology were defining the unique features of the synapse as a site for cell to cell signaling in the late fifties, neurochemistry was establishing the identity and studying the biosynthetic pathways of monoamine neurotransmitters. Meanwhile, neuropsychiatry was keeping a vigilant eye on the outcome of this concerted effort with the untold hope that a genetic defect in neurotransmitter metabolism would ac count for the pathogenesis of certain psychiatric ill nesses. Thus, when neurochemists in the early sixties began to study the feasibility of measuring the metabolism of brain neurotransmitters in vivo, clinical biochemists eagerly adopted these methods to their needs and sought to verify whether inborn errors of transmitter biogenesis were a cause for at least certain forms of depression, mania and schizophrenia. Undoubtedly, it is still too early to evaluate the outcome of these studies. However, current opinion holds that gross inborn errors in transmitter metabolism do not anpear to be operative as a primary cause of psychia tric disorders. Though monoamine metabolism appears to be defective in certain groups of psychiatric disorders, the cause of these changes can at best be associated with changes in patterns of neuronal firing. It is generally believed that these persistent changes are determined by a number of unknown factors operative in various psychia tric illnesses. In the attempt to identify the molecular nature of these unknown factors, the focus of current research is directed toward transmitter receptors.
