Download or read book CtBP Family Proteins written by G. Chinnadurai and published by Springer Science & Business Media. This book was released on 2008-05-07 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Ctbp family proteins are multifunctional. They predominantly function as transcriptional corepressors in the nucleus by recruiting various histone modifying enzymes such as histone deacetylases, histone methylases and a histone demethylase. This book is a comprehensive monograph on the Ctbp family proteins.
Download or read book Adenoviruses Model and Vectors in Virus Host Interactions written by Walter Doerfler and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: After three volumes on adenoviruses in 1995 the past years have seen rapid progress in the field of adenovirus research. Moreover, adenoviruses have attracted considerable interest as vectors in gene transfer regimens. After the first volume on virion and structure, viral replication and host-cell interaction this second volume deals with the immune system, oncogenesis and gene therapy.
Download or read book Recent Progress in Multivariate Approximation written by Werner Haussmann and published by Springer Science & Business Media. This book was released on 2001 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the main results of the 4th International Conference on Multivariate Approximation, which was held at Witten-Bommerholz, September 24-29, 2000. Nineteen selected, peer-reviewed contributions cover recent topics in constructive approximation on varieties, approximation by solutions of partial differential equations, application of Riesz bases and frames, multiwavelets and subdivision. Features and Topics: interpolation and approximation on compact sets, kergin interpolationerror asymptoticsradial basis functionsenergy minimizing configurations on the spherequadrature and cubature formulaeharmonic functions near a zeroblending functionsframes and approximation of inverse frame operators The book is an essential resource for researchers and graduates in applied mathematics, computer science and geophysics who are interested in the state-of-the-art developments in multivariate approximation.
Download or read book Natural Biomarkers for Cellular Metabolism written by Vladimir V. Ghukasyan and published by CRC Press. This book was released on 2014-09-26 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the Lab to Clinical Settings-Advances in Quantitative, Noninvasive Optical DiagnosticsNoninvasive fluorescence imaging techniques, novel fluorescent labels, and natural biomarkers are revolutionizing our knowledge of cellular processes, signaling and metabolic pathways, the underlying mechanisms for health problems, and the identification of n
Download or read book Gene Sharing and Evolution written by Joram PIATIGORSKY and published by Harvard University Press. This book was released on 2009-06-30 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution.
Download or read book GTPases Regulating Membrane Dynamics written by W. E. Balch and published by Gulf Professional Publishing. This book was released on 2005-12-13 with total page 750 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their expanding list of regulators and effectors. This work also includes methodologies focused on biochemical, molecular and advanced imaging techniques.
Download or read book Signaling Pathways and Molecular Mediators in Metastasis written by Alessandro Fatatis and published by Springer Science & Business Media. This book was released on 2012-01-03 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work presents the most advanced discoveries from translational research laboratories directly involved in identifying molecules and signalling pathways that play an instrumental role in metastasis. In contrast to other works, conventionally focused on a single type of tumour, the various chapters in this book provide a broad perspective of the similarities and discrepancies among the dissemination of several solid malignancies. Through recurrent and overlapping references to molecular mechanisms and mediators, the readers will gain knowledge of the common ground in metastasis from a single source. Finally, an introductory chapter provides a clinical perspective of the problems presented by metastatic tumours for diagnosis and treatment. The work presented here is directed to researchers in tumour biology with a developing interest in metastatic dissemination as well as medical and graduate students seeking to expand and integrate the notions acquired in basic cancer biology and oncology courses.
Download or read book Histone Deacetylases written by Eric Verdin and published by Springer Science & Business Media. This book was released on 2007-11-06 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.
Download or read book NR Coregulators and Human Diseases written by Rakesh Kumar and published by World Scientific. This book was released on 2008 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a treasure for all those who have an interest in nuclear receptor coregulators and human diseases. Written by experts in the field, each chapter provides comprehensive, up-to-date information on the physiologic and pathologic roles of coregulators in specific organ systems, giving biomedical students; basic and clinical researchers; and educators in diverse sub-specialties a thorough summary of the overall subject. Readers will be able to understand the important current information and views on specific coactivators and corepressors and their roles in the pathogenesis of human diseases in areas outside their own expertise or experience. A special emphasis is placed on the ?classic? papers as well as perspectives on future directions for the field.
Download or read book Nuclear Receptors Coregulators And Human Diseases written by Rakesh Kumar and published by World Scientific. This book was released on 2008-03-14 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a treasure for all those who have an interest in nuclear receptor coregulators and human diseases. Written by experts in the field, each chapter provides comprehensive, up-to-date information on the physiologic and pathologic roles of coregulators in specific organ systems, giving biomedical students; basic and clinical researchers; and educators in diverse sub-specialties a thorough summary of the overall subject. Readers will be able to understand the important current information and views on specific coactivators and corepressors and their roles in the pathogenesis of human diseases in areas outside their own expertise or experience. A special emphasis is placed on the “classic” papers as well as perspectives on future directions for the field.
Download or read book Transcriptional Corepressors Mediators of Eukaryotic Gene Repression written by Martin L. Privalsky and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Corepressors are newly discovered assemblies of proteins that play essential roles in eukaryotic gene regulation. Recent discoveries about corepressors have provided new insights into the molecular basis of gene regulation, and have established surprising connections between the mechanisms of action of a wide variety of transcriptional regulators. The reviews in this volume critically discuss the nature, mechanisms of action, and physiological roles of corepressors in a diverse assortment of biological systems. Both basic and clinical investigators will be able to find relevant information. The comprehensive nature of the compilation, and the breadth of the reviews, are intended to provide the reader with an excellent introduction to the newly emergent and rapidly-growing field of corepressor research. A valuable and detailed reference guide.
Download or read book Adenoviral Vectors for Gene Therapy written by David T. Curiel and published by Academic Press. This book was released on 2016-03-10 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adenoviral Vectors for Gene Therapy, Second Edition provides detailed, comprehensive coverage of the gene delivery vehicles that are based on the adenovirus that is emerging as an important tool in gene therapy. These exciting new therapeutic agents have great potential for the treatment of disease, making gene therapy a fast-growing field for research. This book presents topics ranging from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology, and the use of adenoviral vectors in preclinical animal models, with final consideration of the regulatory issues surrounding human clinical gene therapy trials. This broad scope of information provides a solid overview of the field, allowing the reader to gain a complete understanding of the development and use of adenoviral vectors. - Provides complete coverage of the basic biology of adenoviruses, as well as their construction, propagation, and purification of adenoviral vectors - Introduces common strategies for the development of adenoviral vectors, along with cutting-edge methods for their improvement - Demonstrates noninvasive imaging of adenovirus-mediated gene transfer - Discusses utility of adenoviral vectors in animal disease models - Considers Federal Drug Administration regulations for human clinical trials
Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2010 with total page 520 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Analysis of the Ikaros Family of Proteins in Thymocyte Development written by Rupa Sridharan and published by . This book was released on 2006 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2003 with total page 1616 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Download or read book Physical Biochemistry written by Kensal Edward Van Holde and published by Prentice Hall. This book was released on 1985 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cancer Associated Viruses written by Erle S. Robertson and published by Springer Science & Business Media. This book was released on 2012-02-14 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.
