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Book Structure Function Analysis of the Amino Terminal Domain of the Androgen Receptor

Download or read book Structure Function Analysis of the Amino Terminal Domain of the Androgen Receptor written by Leen Callewaert and published by Leuven University Press. This book was released on 2004 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This is a Ph.D. dissertation. The amino-terminal domain (NTD) of the androgen receptor (AR) is indispensable for AR transactivation and contains a strong activation function 1. Its activity is affected by coregulators that influence a number of functional properties of AR. The NTD of the AR is 529 aa long and is a complex domain with several functions, namely p160 recruitment, interaction with the LBD, and it contains two transactivation functions Tau-1 And Tau-5. The aim of this study was to obtain a more detailed structure-function analysis of the NTD of the AR. Contents include: Introduction, N/C Interaction in AR-mediated Transactivation, Polyglutamine Stretch, SUMOylation of the AR, Activation Function of the hAR, Discussion, Summary and conclusions, Future Prospects."

Book Core Promoter Elements as Selective Determinants of Transcriptional Activation by VP16   Sp1

Download or read book Core Promoter Elements as Selective Determinants of Transcriptional Activation by VP16 Sp1 written by Katayoon Hojjati-Emami and published by . This book was released on 1997 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Transcription Factors

    Book Details:
  • Author : Manfred Gossen
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 3642189326
  • Pages : 573 pages

Download or read book Transcription Factors written by Manfred Gossen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

Book Regulation of Gene Expression in Animal Viruses

Download or read book Regulation of Gene Expression in Animal Viruses written by Luis Carrasco and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses, being obligatory parasites of their host cells, rely on a vast supply of cellular components for their replication, regardless of whether infection leads to cell death or to the state of persistence. Animal viruses are providing scientists with relatively simple models to study the molecular biology of genome replication and gene expression. Whereas viruses use, in general, pathways of macromolecular biosynthesis common to the host cell, they have a cunning ability to adopt unusual mechanisms of gene expression and gene replication, provided these special pathways offer an advantage in competition for cellular resources. Any study of viral gene expression and replication is likely to lead also to new insights in cellular metabolism. The discoveries of cis-acting regulatory elements in transcription, the phenomenon of splicing of pre mRNA, and cap-dependent and cap-independent initiation of translation may be cited as examples. In addition, animal virus genomes contain elements and encode proteins that are very useful for the design of vectors for gene cloning and expression in mammalian cells. Apart from the basic interest in their biology, viruses have gained notoriety, of course, because they are pathogens. Human animal viruses may cause diseases ranging from the deadly (AIDS) to the benign (common cold). All studies on animal viruses potentially lead to the development of tools for their control, be it through prevention by immunization or treatment with antiviral drugs. Finally, viruses have yielded invaluable reagents in molecular biology as, for example, the vaccinia virus vector for the expression of foreign genes.

Book Chromatin

    Book Details:
  • Author : Alan P. Wolffe
  • Publisher : Academic Press
  • Release : 2012-12-02
  • ISBN : 0080926606
  • Pages : 462 pages

Download or read book Chromatin written by Alan P. Wolffe and published by Academic Press. This book was released on 2012-12-02 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and concise fashion, with 60 new illustrations. Chromatin: Structure and Function provides the reader with a concise and coherent account of the nature, structure, and assembly of chromatin and its active involvement in the processes of DNA transcription, replication and repair. This book consistently interrelates the structure of eukaryotic DNA with the nuclear processes it undergoes, and will be essential reading for students and molecular biologists who want to really understand how DNA works. - Written in a clear and concise fashion - Includes 60 new illustrations - Extensively rewritten - Brings the reader up-to-date with the remarkable progress in chromatin research over the past three years.

Book Dancing Protein Clouds  Intrinsically Disordered Proteins in the Norm and Pathology  Part C

Download or read book Dancing Protein Clouds Intrinsically Disordered Proteins in the Norm and Pathology Part C written by and published by Academic Press. This book was released on 2021-10-14 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Part C, Volume 183 represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this volume include discussions on the evolution of disorder, consideration of the peculiarities of phase separation of the prion protein, a general discussion of the relationships between intrinsic disorder and protein functions, coverage of the structural and functional characterization of several important intrinsically disordered proteins, such as transcription factors, outer membrane porins, trans-membrane and membrane associated proteins with ID regions, discussion of molecular simulations of IDPs, and much more. Provides recent studies on the intrinsically disordered proteins and their functions, along with the involvement of intrinsically disordered proteins in the pathogenesis of various diseases Contains numerous illustrative materials (color figures, diagrams and tables) to help readers delve into the information provided Includes contributions from recognized experts in the field

Book Mutational and Fluorescence Analysis of a Transcriptional Activation Domain of the VP16 Protein of Herpes Simplex Virus

Download or read book Mutational and Fluorescence Analysis of a Transcriptional Activation Domain of the VP16 Protein of Herpes Simplex Virus written by Susan M. Sullivan and published by . This book was released on 1998 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Yeast Sugar Metabolism

Download or read book Yeast Sugar Metabolism written by Friedrich K. Zimmermann and published by CRC Press. This book was released on 1997-03-10 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Yeast Sugar Metabolism looks at the biomechanics, genetics, biotechnology and applications of yeast sugar. The yeast Saccharomyces cereisiae has played a central role in the evolution of microbiology biochemistry and genetics, in addition to its use of a technical microbe for the production of alcoholic beverages and leavening of dough.

Book Mechanisms of Transcriptional Activation by ZEBRA

Download or read book Mechanisms of Transcriptional Activation by ZEBRA written by Tianhuai Chi and published by . This book was released on 1996 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Gene Expression Systems

    Book Details:
  • Author : Joseph M. Fernandez
  • Publisher : Elsevier
  • Release : 1998-12-21
  • ISBN : 0080532357
  • Pages : 493 pages

Download or read book Gene Expression Systems written by Joseph M. Fernandez and published by Elsevier. This book was released on 1998-12-21 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Expression Systems: Using Nature for the Art of Expression offers detailed information on a wide variety of gene expression systems from an array of organisms. It describes several different types of expression systems including transient, stable, viral, and transgenic systems. Each chapter is written by a leader in the field. The book includes timelines and examples for each expression system, and provides an overview of the future of recombinant protein expression. - Provides detailed information on expression systems - Covers a variety of promoters and host organisms enabling researchers to tailor protocols to their specific needs - Includes timelines and examples - Compares pros and cons of each method

Book Mimicking Transcriptional Activation Domains with 7 Oxanorbornene Derivatives

Download or read book Mimicking Transcriptional Activation Domains with 7 Oxanorbornene Derivatives written by Zikiya Inez Heichel Norton and published by . This book was released on 2007 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Gene Expression

    Book Details:
  • Author : M. Karin
  • Publisher : Springer Science & Business Media
  • Release : 2013-03-08
  • ISBN : 1468468111
  • Pages : 313 pages

Download or read book Gene Expression written by M. Karin and published by Springer Science & Business Media. This book was released on 2013-03-08 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first volume in a new series Progress in Gene Expres sion. The control of gene expression is a central-most topic in molecular biology as it deals with the utilization and regulation of gene informa tion. As we see huge efforts mounting all over the developed world to understand the structure and organization of several complex eukaryotic genomes in the form of Gene Projects and Genome Centers, we have to remember that without understanding the basic mechanisms that gov ern the use of genetic information, much of this effort will not be very productive. Fortunately, however, research during the past seven years on the mechanisms that control gene expression in eukaryotes has been extremely successful in generating a wealth of information on the basic strategies of transcriptional control. (Although regulation of gene ex pression is exerted at many different levels, much of the emphasis in this series will be on transcriptional control. A future volume, however, will deal with other levels of regulation). The progress in understanding the control of eukaryotic transcription can only be appreciated by realizing that seven years ago we did not know the primary structure of a single sequence specific transcriptional activator, and those whose primary structures were available (e. g. , homeo domain proteins) were not yet recognized to function in this capacity.