Download or read book Critical Reviews in Oncogenesis written by and published by . This book was released on 1990 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book How Tobacco Smoke Causes Disease written by United States. Public Health Service. Office of the Surgeon General and published by . This book was released on 2010 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Download or read book Human Herpesviruses written by Ann Arvin and published by Cambridge University Press. This book was released on 2007-08-16 with total page 1325 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive account of the human herpesviruses provides an encyclopedic overview of their basic virology and clinical manifestations. This group of viruses includes human simplex type 1 and 2, Epstein–Barr virus, Kaposi's Sarcoma-associated herpesvirus, cytomegalovirus, HHV6A, 6B and 7, and varicella-zoster virus. The viral diseases and cancers they cause are significant and often recurrent. Their prevalence in the developed world accounts for a major burden of disease, and as a result there is a great deal of research into the pathophysiology of infection and immunobiology. Another important area covered within this volume concerns antiviral therapy and the development of vaccines. All these aspects are covered in depth, both scientifically and in terms of clinical guidelines for patient care. The text is illustrated generously throughout and is fully referenced to the latest research and developments.
Download or read book Issues in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume. The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures. The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.
Download or read book Published Scientific Papers of the National Institutes of Health written by National Institutes of Health (U.S.) and published by . This book was released on 1990 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book List of Journals Indexed in Index Medicus written by National Library of Medicine (U.S.) and published by . This book was released on 1996 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: Issues for 1977-1979 include also Special List journals being indexed in cooperation with other institutions. Citations from these journals appear in other MEDLARS bibliographies and in MEDLING, but not in Index medicus.
Download or read book Stell Maran s Textbook of Head and Neck Surgery and Oncology written by John Watkinson and published by CRC Press. This book was released on 2011-12-30 with total page 1181 pages. Available in PDF, EPUB and Kindle. Book excerpt: First written by Philip Stell and Arnold Maran in 1972, Stell & Maran's Textbook of Head and Neck Surgery and Oncology has been revised in both content and approach over the years to reflect the enormous progress made in the area. Now in its fifth edition, the book remains a key textbook for trainees in otolaryngology and head and neck surgery.
Download or read book Non Mutagenic Carcinogens written by Nordic Council Of Ministers Staff and published by Nordic Council of Ministers. This book was released on 1998 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: Non-Mutagenic Carcinogens
Download or read book Thyroid Cancer written by James A. Fagin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of its relative rarity and favorable outcome, it has not been feasible to assess medical interventions for thyroid cancer using randomized prospective trials. The approach to diagnosis and treatment relies to a great extent on information derived from retrospective studies. Overall prognosis and survival rates have been edging upward over the past two decades. This is attributed to a wider acceptance of total thyroidectomy as the primary surgical strategy. The appropriate indication of radioiodine therapy remains controversial, and physicians must be familiar with staging criteria to make educated decisions. We are now beginning to understand the genetic mechanisms of thyroid tumor initiation and progression. There are still major challenges ahead. Thyroid Cancer provides comprehensive updates on the epidemiology, pathogenesis, diagnosis and treatment of thyroid neoplasms. Although the material should be of particular interest to scholars in the field, the contributors have striven to make it of practical use to physicians who treat patients with thyroid disease.
Download or read book Handbook of Cancer Related Fatigue written by Roberto Patarca-Montero and published by CRC Press. This book was released on 2004-06-22 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognize and treat fatigue as a major symptom of cancer and cancer treatment! The Handbook of Cancer-Related Fatigue, by Dr. Roberto Patarca-Montero, the editor of the Chronic Fatigue Syndrome series from The Haworth Medical Press, focuses exclusively on fatigue as it relates to oncology. As more people every year are affected by cancer, treating the leading symptom becomes as important as treating the disease itself. Written by one of the world’s leading experts in the study of fatigue, this detailed work studies the causes, impact, and treatment of fatigue before, during, and after cancer treatment. Considered one of the most distressing yet common symptoms of cancer, fatigue must be allayed to improve the patient’s quality of life. The Handbook of Cancer-Related Fatigue studies the close relationship between fatigue and cancer, as well as cancer therapies that cause fatigue. This book identifies fatigue’s devastating effects on the body and mind and offers solutions to maximize care for all types of cancer victims using documented clinical studies from around the world. For those interested in pursuing more information, an extensive bibliography is included for all relevant text. The Handbook of Cancer-Related Fatigue provides extensive research on: determining a diagnosis of cancer-related fatigue and recognizing the syndrome at all stages of treatment long-term and short-term effects of fatigue on the cancer victim’s body and its impact on the patient’s care and treatment, even after the cancer goes into remission the underlying factors within the body systems that contribute to cancer-related fatigue numerous beneficial intervention techniques to allay the effects of cancer-related fatigue on the patient’s quality of life clinical studies showing the statistics of cancer-related fatigue in the United States and around the world identifying the relationship between cancer and fatigue using tables, references, sidebars, and an extensive bibliography and much more! Focused and thorough, The Handbook of Cancer-Related Fatigue is written for both cancer patients and health-care providers of all disciplines. Whether you are an oncologist, a therapist, or a patient, vital information is not only accessible but made easier to understand with handy charts, tables, and referenced clinical studies throughout the chapters. With fatigue categorized as one of the most important symptoms of cancer, it becomes imperative for anyone touched by this disease—personally or professionally—to keep a copy of this book at hand.
Download or read book Programmed Cell Death written by Martin Lavin and published by CRC Press. This book was released on 1993-12-08 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Only recently have the cellular and molecular aspects of cell suicide (or perhaps euthanasia) been investigated. From a September 1992 symposium in Brisbane, 26 papers report advances in the biochemical mechanisms, DNA fragmentation, genetic regulation, and apoptosis in the immune system and in cancer. Annotation copyright by Book News, Inc., Portland, OR
Download or read book Breast Cancer written by W.P. Peters and published by Elsevier. This book was released on 1998-08-25 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast cancer research has never been in such an exciting and hopeful phase as today. From a clinical perspective, the discovery of genetic markers of risk in a proportion of familial breast cancer cases has opened up new vistas for understanding and ultimately preventing this disease. On the other hand, aggressive - even daring - therapies are being proven to be effective against advanced breast cancer. For the breast cancer experimentalist, this is also a time of great advance. Although animal and cell culture breast cancer models have proven to be of great use, there are now increasing opportunities to test the concepts developed in these models in actual clinical samples and cases. It is gratifying to see how well these concepts "translate" into the clinical setting. A very active area of research that is linking the laboratory to the clinic is the dissection of the biology and elucidation of the significance of proliferate breast disease and the identification of true, "high risk" or "preneoplastic" legions within the previously ill-defined spectrum of fibrocystic or benign breast disease. One anticipates that discoveries made here will also lead to earlier detection, intervention and prevention of life-threatening cancer.Even, however, as we look with optimism to the eventual eradication of breast cancer, we are once again forced to face the reality that we have not yet achieved our goal. Thus, we are saddened by the much too premature death of Dr. Helene Smith from breast cancer. Helena's work was at the forefront of efforts to understand the biology of human breast cancer at the molecular level. Her insight, open-mindedness, and refusal to sacrifice relevance for convenience will continue to set the standard for all breast cancer researchers. This volume is dedicated to her memory.
Download or read book Medical Etiology Assessment and Treatment of Chronic Fatigue and Malaise written by Roberto Patarca-Montero and published by CRC Press. This book was released on 2004-10-29 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: A handy reference guide to living with fatigue! Medical Etiology, Assessment, and Treatment of Chronic Fatigue and Malaise: Clinical Differentiation and Intervention is the single reference source you need for vital information on the fatiguing illnesses that affect more than 800,000 Americans. Written by one of the foremost experts in the field, the book is a comprehensive guide to the debilitating, and often misunderstood, phenomenon of fatigue, examining its multiple causes and treatments. Through a detailed history of chronic fatigue and a look at the factors that influence evaluation, diagnosis, and treatment, the book gives you immediate access to the answers you—and your patients—have been searching for. Practical and easy-to-use, Medical Etiology, Assessment, and Treatment of Chronic Fatigue and Malaise: Clinical Differentiation and Intervention saves you the time and trouble of sorting through extensive research findings for the information you need on the many contexts and consequences of fatigue. The book examines how fatigue is defined and measured and how it relates to autoimmune diseases, cancer, neurological disease, and a variety of other pathologies. You’ll also get immediate access to the latest related findings in cardiovascular medicine, epidemiology, infectious diseases, endocrinology, psychology, and psychiatry that served as the basis for research and therapeutic interventions. Medical Etiology, Assessment, and Treatment of Chronic Fatigue and Malaise: Clinical Differentiation and Intervention provides valuable information on: complicating factors in the diagnosis and treatment of fatigue symptom distress and quality of life body defense factors fatigue perception and severity chronic fatigue syndrome fatigue and the environment predisposed and perpetuating factors for chronic fatiguing illnesses cytokines endocrine factors and much more! Medical Etiology, Assessment, and Treatment of Chronic Fatigue and Malaise: Clinical Differentiation and Intervention also includes tables, figures, and references. This accessible reference guide is crucial for anyone suffering the effects of this baffling disorder and for the healthcare professionals they depend on.
Download or read book Regulation of Gene Expression in Animal Viruses written by Luis Carrasco and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses, being obligatory parasites of their host cells, rely on a vast supply of cellular components for their replication, regardless of whether infection leads to cell death or to the state of persistence. Animal viruses are providing scientists with relatively simple models to study the molecular biology of genome replication and gene expression. Whereas viruses use, in general, pathways of macromolecular biosynthesis common to the host cell, they have a cunning ability to adopt unusual mechanisms of gene expression and gene replication, provided these special pathways offer an advantage in competition for cellular resources. Any study of viral gene expression and replication is likely to lead also to new insights in cellular metabolism. The discoveries of cis-acting regulatory elements in transcription, the phenomenon of splicing of pre mRNA, and cap-dependent and cap-independent initiation of translation may be cited as examples. In addition, animal virus genomes contain elements and encode proteins that are very useful for the design of vectors for gene cloning and expression in mammalian cells. Apart from the basic interest in their biology, viruses have gained notoriety, of course, because they are pathogens. Human animal viruses may cause diseases ranging from the deadly (AIDS) to the benign (common cold). All studies on animal viruses potentially lead to the development of tools for their control, be it through prevention by immunization or treatment with antiviral drugs. Finally, viruses have yielded invaluable reagents in molecular biology as, for example, the vaccinia virus vector for the expression of foreign genes.
Download or read book Chronic Fatigue Syndrome and the Body s Immune Defense System written by Roberto Patarca-Montero and published by CRC Press. This book was released on 2002-09-20 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: New evidence on the origins and treatment of chronic fatigue syndrome! Written by one of the leading experts in the field, Chronic Fatigue Syndrome and the Body?s Immune Defense System presents vital new information on a crippling disorder that has the biomedical community searching for answers. Current research suggests CFS is associated with immune abnormalities that can potentially account for its origin and development. With at least one-third of tested CFS patients showing evidence of activation of the body?s “immune army,” this book is crucial reading for all patients with CFS and for the healthcare professionals they trust. Chronic Fatigue Syndrome and the Body?s Immune Defense System presents a thorough examination of the connection between immunology and this debilitating disorder. The book is essential as a primer on the human immune system (explaining fundamental terms and concepts), an overview of immunopathology, and a review of therapeutic interventions that are immune-based. It also explores the links between immune, endocrine, and nervous system abnormalities and the need for a combined research approach to understanding the different manifestations of CFS. Chronic Fatigue Syndrome and the Body?s Immune Defense System explains: how infectious viruses, bacteria, and fungi could be direct causes of CFS how therapeutic tools like herbal medicine, vaccines, and cell therapy are being used in CFS research how CFS research applies to related conditions, such as fibromyalgia, Gulf War syndrome, sick building syndrome, and multiple chemical sensitivity With a consensus diagnostic tool for CFS still lacking, continued, aggressive research is vital to solving the riddle of its origin. Chronic Fatigue Syndrome and the Body?s Immune Defense System represents a significant step forward in the search, giving new hope to patients and new insight to healthcare professionals.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cellular Senescence in Disease written by Manuel Serrano and published by Academic Press. This book was released on 2021-11-27 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2023 PROSE award in Biomedicine and Neuroscience! Research in the field of senescence has boomed recently due to the gradual realization that senescent cells are associated with a significant number of diseases. The genetic or pharmacological elimination of senescent cells can cause widespread benefits and improves outcomes for most of those diseases. Cellular Senescence in Diseases presents an updated review of the role of cellular senescence in multiple pathologies. Focus is given to those diseases where the implication of senescence has been more extensively documented, such as (cancer, lung and liver diseases, diabetes, Neurodegenerative diseases and others). The Editors recruited a group of worldwide experts in each individual pathology to review the role of cellular senescence in each one of them, aiming at identifying potential therapeutic pathways. The first two chapters provide an overview of the cellular senescence principles. Next, the chapters are divided into specific diseases. Cancer, including premalignant lesions (OIS), Advanced disease (TIS), and Metastasis are covered. The following condition covered is Lund diseases, including IPF, COPD, and Pulmonary Hypertension. Next Liver Diseases are covered, including Fibrosis and Cirrhosis, and Fatty liver disease. Next there is coverage for Kidney implications, including fibrosis and transplantation. Vascular diseases are covered next including infarction and hear fibrosis, and atherosclerosis. Both diabetes types 1 and 2 are covered next. Following chapters cover Obesity, Sarcopenia, and Bone and Cartilage disorders, respectively. Neurodegenerative diseases are covered next, focusing on Alzheimer and Parkinson. The next chapter discusses accumulation of senescent cell in tissues during aging. The two final chapters cover current developments and conclusions. Cellular Senescence in Diseases is designed for researchers and clinicians with a focus on the cellular mechanisms of diseases. All chapters cover current experimental therapeutic approaches to eliminate or cancel the pathological effects of senescent cells. Pharmaceutical scientists may also benefit from the contents of the book in the exploration of novel therapeutic opportunities. 2023 PROSE Awards - Winner: Category: Biomedicine and Neuroscience: Association of American Publishers Provides a thorough introduction to Cellular Senescence Covers all major pathologies for which cellular senescence has shown evidence of involvement Focuses on possible therapeutic pathways Edited and authored by worldwide experts
