Download or read book Stroke Genetics written by Hugh S. Markus and published by Oxford Medical Publications. This book was released on 2003 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.
Download or read book Imaging Coronary Atherosclerosis written by Stephen J. Nicholls and published by Humana. This book was released on 2016-09-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over 50 years, coronary angiography has been the mainstay of diagnosing and quantifying the extent of coronary artery disease. However appreciation of the inherent limitations of conventional angiography has led to a plethora of new imaging modalities, each with their relative strengths and potential pitfalls. Advances in these techniques have given clinicians, as well as researchers, an overwhelming amount of information and the need for thoughtful interpretation. This outstanding book provides a comprehensive overview of the current status of imaging of coronary atherosclerosis. Covering the wide variety of available imaging modalities, the book provides state-of-the-art knowledge from leading authorities in each area. In their discussion, the authors include both invasive and non-invasive modalities, including the gold standard coronary angiography, the growing field of IVUS, and novel techniques such as functional imaging, molecular imaging, and the integration of biomarkers. The key concepts and practical information given in this volume will provide the reader with the necessary understanding to choosing appropriate imaging studies and building confidence in their skill set with each.
Download or read book Cardiovascular Disability written by Institute of Medicine and published by National Academies Press. This book was released on 2010-12-04 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
Download or read book Translational Research in Coronary Artery Disease written by Wilbert S. Aronow and published by Academic Press. This book was released on 2015-10-29 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. Provides a concise summary of recent developments in coronary and vascular research, including previously unpublished data Summarizes in-depth discussions of the pathobiology and novel treatment strategies for coronary artery disease Provides access to an accompanying website that contains photos and videos of noninvasive diagnostic modalities for evaluation of coronary artery disease
Download or read book Coronary Artery Disease Therapeutics and Drug Discovery written by Miao Wang and published by Springer Nature. This book was released on 2020-04-03 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
Download or read book Chronic Coronary Artery Disease A Companion to Braunwald s Heart Disease E Book written by James de Lemos and published by Elsevier Health Sciences. This book was released on 2017-01-03 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Featuring expert guidance from Drs. James de Lemos and Torbjørn Omland, as well as other globally known leaders in cardiology, Chronic Coronary Artery Disease covers every aspect of managing and treating patients suffering from chronic coronary syndromes. This brand-new companion to Braunwald's Heart Disease was designed as a stand-alone reference for physicians treating patients who present with complex, unique challenges, offering the latest information on the use of imaging modalities in diagnosis and treatment, advances in interventional and surgical approaches to revascularization, new medications to improve symptoms and outcomes in chronic CAD, and much more. Covers every aspect of evaluation and treatment of patients who suffer from chronic coronary syndromes. Provides both evidenced based recommendations from the most recent guidelines from the major cardiology societies: AHA, ACC, and ESC, as well as practical management tips from leading experts with extensive clinical experience. Highlights new developments concerning epidemiology and prevention, pathophysiology, and clinical findings, as well as laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, and prognosis and management of chronic coronary syndromes. Features information on today's hot topics, including the use of novel imaging modalities in diagnosis and treatment and emerging therapies to improve outcomes in chronic CAD.
Download or read book Coronary Artery Disease written by Dimitris Tousoulis and published by Academic Press. This book was released on 2017-10-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary Artery Disease: From Biology to Clinical Practice links the most important basic concepts of atherosclerosis pathophysiology to treatment management of coronary artery disease. Comprehensive coverage starts with the basic pathophysiologic mechanisms of the disease, including molecular and genetic mechanisms, cells interaction and inflammation. In addition, sections on novel anti-atherosclerotic therapies and a thorough understanding of the recent trends in clinical management round out this comprehensive tome that is ideal for practitioners and researchers. By summarizing this novel knowledge and changes in diagnostic algorithm and treatment options, this is the perfect reference for cardiology researchers who want a volume with the most up-to-date experimental trends in the field of atherosclerosis, for cardiologists and physicians who manage patients with atherosclerotic risk factors and established coronary artery disease, and medical students who want to learn the basic concepts of atherosclerosis.
Download or read book Biomechanics of Coronary Atherosclerotic Plaque written by and published by Academic Press. This book was released on 2020-03-15 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomechanics of Coronary Atherosclerotic Plaque: From Model to Patient, First Edition, is the first comprehensive text to focus on important biomechanical studies conducted in the last decade that have increased our understanding of coronary atherosclerotic plaque initiation, growth, and rupture, as well as improving the design of medical devices and clinical interventions, including surgical procedures. The book provides students, researchers, engineers, clinicians, and interventional cardiologists with an overview of the main topics related to the biomechanics of atherosclerosis, in a single volume written by several experts in the field. This volume is part of the Biomechanics of Living Organs book series. The biomechanics of human soft tissues and organs has been an emerging research field since the publication of Y.C. Fung’s original book series in the 1990s. The publication of such books entirely dedicated to a specific biomechanical subject is necessary to advance scientific research in the field of biomechanics and to transfer important knowledge to future generations. Therefore, this series of volumes on the biomechanics of living organs has been created. This series began in July 2017 with the publication of a first volume on the fundamentals of Hyperelastic Constitutive Laws for Finite Element Modeling of Living Organs. The current volume on the Biomechanics of Coronary Atherosclerotic Plaque, is the latest in this new series. Presents the main computational fluid dynamic studies performed, describing blood flow in healthy and pathological artery branches, including in coronary bifurcations Highlights the correlation between plaque initiation regions and blood shear stress amplitude Discusses the main biomechanical and mechanobiological models to highlight the importance of quantifying the residual and peak cap stresses and the presence of μ-calcifications to evaluate the risk of plaque rupture Introduces the most recent intravascular imaging biomarker techniques (elastography, palpography and modulography)
Download or read book Live Younger Longer written by Stephen Kopecky and published by Simon and Schuster. This book was released on 2022-02-16 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most of us want to live a long, healthy life, but how do we do that? Drawing upon lessons from his own life, Mayo Clinic cardiologist Stephen Kopecky offers a holistic, evidence-based approach to preventing common diseases and chronic illnesses and living a longer life of pleasure and purpose. In the past century, the leading causes of death around the world have shifted from infectious diseases to long-term chronic illnesses. What’s killing us today isn’t so much flu or tuberculosis, but heart disease and cancer. In fact, more than 1.2 million Americans die from these two diseases each year. Paradoxically, these chronic diseases are a consequence of living longer than ever. But even if we’re living longer, are we living better? The overwhelming number of people now living under the burden of chronic illness indicates otherwise. After surviving two bouts of cancer, Dr. Stephen Kopecky, M.D set out to discover the behaviors people can adopt to live longer lives free of chronic illnesses and diseases. What he discovered was that the answer lies in just six habits that require small changes to your daily life, but reap big results long-term. From adopting better diet and exercise habits to managing stress and sleep, these behaviors will not only preserve your health, they can improve your quality of living and extend your life. The secret, however, lies not just in the steps themselves but in how you accomplish them. This book offers in-depth insights on: The best foods to eat and why Increasing physical activity and improving fitness Why your sleep habits matter The dangers of stress and what to do about them The true impact of alcohol and tobacco on our bodies How to make changes that will last a lifetime After 30 years of research in the field of cardiovascular disease prevention, Dr. Kopecky is sharing what he’s learned from his practice and own personal experience about staying healthy, preventing chronic illnesses, and living younger longer.
Download or read book Frontiers in Cardiovascular Health written by Naranjan S. Dhalla and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Frontiers in Cardiovascular Health varies between and within nations, depend ing upon the level at which the battle is fought for better cardiovascular health. According to the 1997 World Health Report, 15 million deaths (i. e. 30% of the total number of deaths) were attributable to cardiovascular diseases and this number is on the rise. The projection for the year 2020 is quite alarming with an expected cardiovascular mortality reaching 50 million. Much of this burden is projected to occur in developing countries, more specifically in the most populous countries of the world, namely China and India. These countries are already burdened with infectious and parasitic diseases and are trying to eradicate such diseases. With increasing life expectancies people all over the world, especially in developing coun tries, are exposed to degenerative atherosclerosis resulting in increased cardiovascu lar mortality and morbidity. In developing countries, resources available for health care are very limited. For example many of the African countries spend less than $10 per person per year on his/her entire health care let alone cardiovascular health. The average health care budget for nearly two thirds of the global population is well below $100 per year, on a per capita basis. Therefore, in developing countries health promotion and primary prevention are the frontiers by necessity. Improving awareness and health education is not only a matter of choice but is an absolute necessity.
Download or read book Living with Coronary Heart Disease written by Jerome E. Granato and published by JHU Press. This book was released on 2008-11-01 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary heart disease kills more people in the United States than any other heart disorder, and it is the leading cause of death among American women. Jerome E. Granato, a distinguished cardiologist with more than twenty-five years of experience, has created an authoritative and accessible guide to this common condition, providing patients and their families with insight and advice. Dr. Granato begins by describing the basic science of the disease, known also as atherosclerosis, in which arteries become clogged and damaged. He then explains who is at risk and how the disease is detected and diagnosed. He covers all the treatment options, from medications to surgery, and answers such questions as: • How do I know if I have coronary heart disease? • What is a heart attack? • Does my condition need to be treated with surgery? • What are the benefits and risks of balloon angioplasty? • What are stents and how do they work? • How can I manage my condition for the future? He addresses the needs of specific populations, and concludes by discussing how a healthy diet and regular exercise can influence health before and after treatment and how it can help prevent disease. Even after coronary heart disease is diagnosed, its course can be modified. This valuable resource will help patients and their families make some of the most important health care decisions they will ever face.
Download or read book Coronary Artery Disease written by Kaan Kırali and published by BoD – Books on Demand. This book was released on 2015-11-18 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronary artery atherosclerosis is the most common cardiac pathology, which is the primary cause of cardiac mortality. Coronary artery stenosis usually involves the proximal portion of the larger epicardial coronary arteries, but diffuse coronary artery disease is also not rare. Most of the patients with/without several comorbidities have asymptomatic atherosclerotic lesions in the coronary territory, and hence early assessment of coronary artery pathology is of utmost importance. Since early surgical intervention is superior to percutaneous interventions, coronary artery bypass grafting is the first choice for the treatment of coronary artery disease. Coronary revascularization can be performed with different approaches according to the patients risk factors. Preventive treatment of coronary artery disease should be the basic strategy for a healthy system.
Download or read book Coronary Artery Disease written by James T. Willerson and published by Springer. This book was released on 2015-03-11 with total page 786 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular Medicine: Coronary Artery Disease will offer today's most up-to-date, user-friendly guidance on the evaluation, diagnosis, and medical and surgical treatment of this most important aspect of cardiovascular disease and will be on the wish list for every trainee and practicising cardiologist, cardiac surgeon, vascular surgeon, diabetologist, cardiac radiologist and any physician who manages cardiac patients. The book is dedicated to providing comprehensive coverage of every aspect of coronary arterial medicine from cardiac signs and symptoms through imaging and the genetic basis for coronary disease to surgery, interventions, treatment and also to preventive cardiology. The Editor – and a group of contributing world authorities – offer their decades of scientific and clinical experience. A major selling point is the consistent chapter organization, clear design, and engaging text that includes user-friendly features such as tables, lists and treatment boxes. The reader will have all the guidance to diagnose and manage a full range of conditions in a series of textbook resources, while also having access to additional video material from the integral website.
Download or read book Atherosclerosis written by Luigi Gianturco and published by BoD – Books on Demand. This book was released on 2018-08-01 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis is a subject of enormous contention for cardiologists and in general for all medical doctors. With this publication we have given you a concise "state-of-the-art" look at the world of atheroma. Many other elements could be included and so it is only a brief analysis of "today" (the preventive medicine era) and "tomorrow" (transforming the cure medicine era into the care medicine era) but also remembering "yesterday" (the ex-cathedra medicine era). Let's hope our arteries are free from atherosclerotic events: have a good read!
Download or read book Lipid Lowering Therapy and Progression of Coronary Atherosclerosis written by A.V. Bruschke and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique overview of all major angiographic lipid intervention trials, presented by their principal investigators. Basic mechanisms and methodological aspects, including biochemical as well as angiographic aspects, are discussed by experts in these fields. A careful comparison of all available data permits an analysis to be made of what may currently be considered proved, which aspects merit further investigation, and which hypotheses should be rejected. Audience: Clinicians involved in the practice of lipid lowering and investigators involved in lipid-lowering clinical trials. Scientists involved in other areas of lipid research and investigators conducting coronary angiographic trials designed to study the influence of different interventions will find a wealth of information and practical guidelines in this book.
Download or read book Coronary Atherosclerosis written by and published by . This book was released on 2012 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The prevalence of coronary artery disease is increasing due to rising rates of obesity and the fact that a greater number of people are living longer. Coronary Atherosclerosis: Current Management and Treatment addresses this leading cause of death worldwide. Atherosclerosis has a broad range of disease manifestations depending on the degree of the stenosis and the functional status of the coronary plaque. This volume, written by a leading international team of editors, addresses the pathophysiology of the disease, established and novel diagnostic approaches (both invasive and non-invasive), treatment methodologies (including treatment algorithms), and differing perspectives on treatment, including future therapies and long-term outcomes. The inclusion of personal perspectives from experts, full-color images and ancillary video files make this a key resource. Key topics include:Pharmacology of coronary artery disease (CAD) Up-to-date evidence on pathophysiology Invasive and non-invasive imaging Current evidence for risk stratification Clinical decisionmaking Coronary Atherosclerosis: Current Management and Treatment provides a state-of-the-art review of current knowledge to aid specialists, general physicians, and cardiologists in training, in the diagnosis, risk stratification, and management of patients with diverse presentations of coronary atherosclerosis.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
