Download or read book Contemporary Aspects of Biomedical Research written by and published by Academic Press. This book was released on 2009-11-24 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental. Articles written by leading investigators in the field Informs and updates on all the latest developments

Download or read book Contemporary Aspects of Endocrinology written by Evanthia Diamanti-Kandarakis and published by BoD – Books on Demand. This book was released on 2011-11-30 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide readers with a general as well as an advanced overview of the key trends in endocrine disorders. While covering a variety of topics ranging from thyroid carcinogenesis and pituitary adenomas to adrenal tumors and metabolic bone disease, this book also focuses on more specific issues not yet fully elucidated (e.g. the molecular pathways involved in thyrotropin beta gene regulation or monogenic phosphate balance disorders). Readers of different fields and background will have the opportunity to update their knowledge and more importantly to clarify areas of uncertainty and controversies in several topics of endocrine disorders.

Download or read book Rethinking Causality Complexity and Evidence for the Unique Patient written by Rani Lill Anjum and published by Springer Nature. This book was released on 2020-06-02 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book is a unique resource for health professionals who are interested in understanding the philosophical foundations of their daily practice. It provides tools for untangling the motivations and rationality behind the way medicine and healthcare is studied, evaluated and practiced. In particular, it illustrates the impact that thinking about causation, complexity and evidence has on the clinical encounter. The book shows how medicine is grounded in philosophical assumptions that could at least be challenged. By engaging with ideas that have shaped the medical profession, clinicians are empowered to actively take part in setting the premises for their own practice and knowledge development. Written in an engaging and accessible style, with contributions from experienced clinicians, this book presents a new philosophical framework that takes causal complexity, individual variation and medical uniqueness as default expectations for health and illness.

Download or read book Technical Abstract Bulletin written by Defense Documentation Center (U.S.) and published by . This book was released on 1964 with total page 1148 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Three Dimensional Human Organotypic Models for Biomedical Research written by Fabio Bagnoli and published by Springer Nature. This book was released on 2021-05-20 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, cancer, allergies, as well as drug/vaccine discovery and toxicology studies. Representing a valid alternative to laboratory animals, these models are relevant for most areas of translational research. As the contemporary research shows, many human tissues can today be cultivated in vitro and used for several research objectives. This book provides an unprecedented overview of recent developments in an exciting field of research methodology. It is a reference guide for scientists in both academia and industry. Readers can update their knowledge and get hands-on recommendations on how to set up an organotypic model in their lab. Chapters 'Progress on Reconstructed Human Skin Models for Allergy Research and Identifying Contact Sensitizers' and 'Human Organotypic Models for Anti-infective Research' of this book are available open access under a CC BY 4.0 license at link.springer.com.

Download or read book Biosciences 2000 Current Aspects And Prospects Into The Next Millenium written by Charles A Pasternak and published by World Scientific. This book was released on 1999-08-16 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the new millennium approaches, it is appropriate to ask how far medicine and the life sciences have brought us, and to wonder how specific fields will develop over the next decade or so.This volume gathers together a number of leading scientists to give a bird's eye view of their field. Much of the emphasis is on cancer, microbial infections and immunology, because these are some of the most rapidly advancing areas of research. However, the book is wide-ranging and interdisciplinary, and covers topics as diverse as reproductive health technology, animal-to-human transplants, drug resistance, non-invasive diagnosis by magnetic resonance, novel membrane technology, and carbon nanotubes. The graduate student faced with a decision regarding his or her future topic of research could do worse than browse through this collection of articles by experts in the field.

Download or read book Managing the NIH Bethesda Campus Capital Assets for Success in a Highly Competitive Global Biomedical Research Environment written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-11-02 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. Founded in the late 1870s, NIH has produced extraordinary advances in the treatment of common and rare diseases and leads the world in biomedical research. It is a critical national resource that plays an important role in supporting national security. The 310-acre Bethesda campus supports some 20,000 employees and contractors, and it contains more than 12 million square feet of facilities divided amongst nearly 100 buildings, including the largest dedicated research hospital in the world. The Bethesda campus supports some of the most sophisticated and groundbreaking biomedical research in the world. However, while some new state-of-the-art buildings have been constructed in recent years, essential maintenance for many facilities and the campus overall has been consistently deferred for many years. The deteriorating condition of NIH's built environment is now putting its ability to fulfill its mission at substantial risk. Managing the NIH Bethesda Campus's Capital Assets for Success in a Highly Competitive Global Biomedical Research Environment identifies the facilities in greatest need of repair on the Bethesda campus and evaluates cost estimates to determine what investment is needed for the NIH to successfully accomplish its mission going forward.

Download or read book Glutamate based Therapies for Psychiatric Disorders written by Phil Skolnick and published by Springer Science & Business Media. This book was released on 2010-09-07 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Both metabotropic and ionotropic glutamate receptors present attractive “druggable” targets in treating disorders of the central nervous system. There has been a dramatic shift in the focus of glutamate-based therapies away from neurologic disorders such as stroke and traumatic brain injury to the treatment of psychiatric disorders. This “Milestones in Drug Therapy” volume offers a unique, contemporary overview of preclinical and clinical evidence that modulating glutamatergic tone is an effective means of treating psychiatric disorders ranging from depression and anxiety to schizophrenia and drug abuse. The ability to treat diseases such as depression and schizophrenia through multiple, glutamate-based mechanisms offers a unique therapeutic opportunity, as described in this book.

Download or read book The Bloomsbury Companion to Contemporary Philosophy of Medicine written by James A. Marcum and published by Bloomsbury Publishing. This book was released on 2016-12-15 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A definitive and authoritative guide to a vibrant and growing discipline in current philosophy, The Bloomsbury Companion to Contemporary Philosophy of Medicine presents an overview of the issues facing contemporary philosophy of medicine, the research methods required to understand them and a trajectory for the discipline's future. Written by world leaders in the discipline, this companion addresses the ontological, epistemic, and methodological challenges facing philosophers of medicine today, from the debate between evidence-based and person-centered medicine, medical humanism, and gender medicine, to traditional issues such as disease, health, and clinical reasoning and decision-making. Practical and forward-looking, it also includes a detailed guide to research sources, a glossary of key terms, and an annotated bibliography, as well as an introductory survey of research methods and discussion of new research directions emerging in response to the rapid changes in modern medicine. "Philosophy needs medicine', Hillel Braude argues, 'to become more relevant'. By showing how modern medicine provides philosophers with a rich source of material for investigating issues facing contemporary society, The Bloomsbury Companion to Contemporary Philosophy of Medicine introduces the opportunities medicine offers philosophers together with the resources and skills required to contribute to contemporary debates and discussions.

Download or read book Modern Aspects of the Circulation in Health and Disease written by Carl John Wiggers and published by . This book was released on 1923 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Modeling in Biomedical Research written by Yichuan Zhao and published by Springer Nature. This book was released on 2020-03-19 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This edited collection discusses the emerging topics in statistical modeling for biomedical research. Leading experts in the frontiers of biostatistics and biomedical research discuss the statistical procedures, useful methods, and their novel applications in biostatistics research. Interdisciplinary in scope, the volume as a whole reflects the latest advances in statistical modeling in biomedical research, identifies impactful new directions, and seeks to drive the field forward. It also fosters the interaction of scholars in the arena, offering great opportunities to stimulate further collaborations. This book will appeal to industry data scientists and statisticians, researchers, and graduate students in biostatistics and biomedical science. It covers topics in: Next generation sequence data analysis Deep learning, precision medicine, and their applications Large scale data analysis and its applications Biomedical research and modeling Survival analysis with complex data structure and its applications.

Download or read book Modern Aspects of Electrochemistry written by J. O’M. Bockris and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present collection of articles follows the arrangement used in previous volumes. Solutions are discussed first, surfaces and double layers second, electrode kinetics third, and then the applied subjects. The introduction of spectroscopic methods to electrochemistry is well exemplified by NMR studies of ionic solutions, as represented here in the detailed article by E. von Goldammer. Correspondingly, the spectroscopic approach can be applied to surfaces, and B. G. Baker has written an introduction to this topic for electrochemists from the point of view of gas phase measurements. One of the topics which begins to reach a degree of sophistica tion in electrode process chemistry is the adsorption of organic species on electrodes, and this topic is described in our volume by the well-known electrochemist M. W. Breiter. The work has much rele vance to the corresponding electrode kinetics and oxidation of organic materials. Much less sophisticated is the position in the electrochemistry of sulfide minerals, but it has seemed worthwhile to have the present record described by D. F. A. Koch; his chapter demonstrates the value of qualitative electrochemical studies in this field. The Hydrogen Economy is perhaps an example of straw fire in electrochemistry, for its great popularity beginning in 1973 reflects an interest which can hardly grow larger. However, much discussion of the Hydrogen Economy is concerned with its nonelectrochemical v vi Preface aspects and D. P. Gregory gives here the latest from the hydrogen front, with emphasis on the electrochemistry.

Download or read book Contemporary Issues for Protecting Patients in Cancer Research written by Sharyl J. Nass and published by . This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the nearly 40 years since implementation of federal regulations governing the protection of human participants in research, the number of clinical studies has grown exponentially. These studies have become more complex, with multisite trials now common, and there is increasing use of archived biospecimens and related data, including genomics data. In addition, growing emphasis on targeted cancer therapies requires greater collaboration and sharing of research data to ensure that rare patient subsets are adequately represented. Electronic records enable more extensive data collection and mining, but also raise concerns about the potential for inappropriate or unauthorized use of data, bringing patient protections into a new landscape. There are also long-standing concerns about the processes and forms used to obtain informed consent from patients participating in clinical studies. These changes and challenges raise new ethical and practical questions for the oversight of clinical studies, and for protecting patients and their health information in an efficient manner that does not compromise the progress of biomedical research. Contemporary Issues for Protecting Patients in Cancer Research is the summary of a workshop convened by the National Cancer Policy Forum of the Institute of Medicine in February 2014 to explore contemporary issues in human subjects protections as they pertain to cancer research, with the goal of identifying potential relevant policy actions. Clinical researchers, government officials, members of Institutional Review Boards, and patient advocates met to discuss clinical cancer research and oversight. This report examines current regulatory provisions that may not adequately protect patients or may be hindering research, and discusses potential strategies and actions to address those challenges.

Download or read book Modern Aspects of Electrochemistry 39 written by Constantinos G. Vayenas and published by Springer Science & Business Media. This book was released on 2006-12-22 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Modern Aspects covers a wide spread of topics presented in an authoritative, informative and instructive manner by some internationally renowned specialists. Professors Politzer and Dr. Murray provide a comprehensive description of the various theoretical treatments of solute-solvent interactions, including ion-solvent interactions. Both continuum and discrete molecular models for the solvent molecules are discussed, including Monte Carlo and molecular dynamics simulations. The advantages and drawbacks of the resulting models and computational approaches are discussed and the impressive progress made in predicting the properties of molecular and ionic solutions is surveyed. The fundamental and applied electrochemistry of the silicon/electrolyte interface is presented in an authoritative review by Dr. Gregory Zhang, with emphasis in the preparation of porous silicon, a material of significant technological interest, via anodic dissolution of monocrystalline Si. The chapter shows eloquently how fundamental electrokinetic principles can be utilized to obtain the desired product morphology. Markov chains theory provides a powerful tool for modeling several important processes in electrochemistry and electrochemical engineering, including electrode kinetics, anodic deposit formation and deposit dissolution processes, electrolyzer and electrochemical reactors performance and even reliability of warning devices and repair of failed cells. The way this can be done using the elegant Markov chains theory is described in lucid manner by Professor Thomas Fahidy in a concise chapter which gives to the reader only the absolutely necessary mathematics and is rich in practical examples.

Download or read book The Ethics of Biomedical Big Data written by Brent Daniel Mittelstadt and published by Springer. This book was released on 2016-08-03 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents cutting edge research on the new ethical challenges posed by biomedical Big Data technologies and practices. ‘Biomedical Big Data’ refers to the analysis of aggregated, very large datasets to improve medical knowledge and clinical care. The book describes the ethical problems posed by aggregation of biomedical datasets and re-use/re-purposing of data, in areas such as privacy, consent, professionalism, power relationships, and ethical governance of Big Data platforms. Approaches and methods are discussed that can be used to address these problems to achieve the appropriate balance between the social goods of biomedical Big Data research and the safety and privacy of individuals. Seventeen original contributions analyse the ethical, social and related policy implications of the analysis and curation of biomedical Big Data, written by leading experts in the areas of biomedical research, medical and technology ethics, privacy, governance and data protection. The book advances our understanding of the ethical conundrums posed by biomedical Big Data, and shows how practitioners and policy-makers can address these issues going forward.

Download or read book Modern Methods of Clinical Investigation written by Institute of Medicine and published by National Academies Press. This book was released on 1990-02-01 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The very rapid pace of advances in biomedical research promises us a wide range of new drugs, medical devices, and clinical procedures. The extent to which these discoveries will benefit the public, however, depends in large part on the methods we choose for developing and testing them. Modern Methods of Clinical Investigation focuses on strategies for clinical evaluation and their role in uncovering the actual benefits and risks of medical innovation. Essays explore differences in our current systems for evaluating drugs, medical devices, and clinical procedures; health insurance databases as a tool for assessing treatment outcomes; the role of the medical profession, the Food and Drug Administration, and industry in stimulating the use of evaluative methods; and more. This book will be of special interest to policymakers, regulators, executives in the medical industry, clinical researchers, and physicians.

Download or read book Women Biomedical Research and Art written by Ninette Rothmüller and published by Verlag Barbara Budrich. This book was released on 2021-06-07 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die Studie widmet sich intersektionalen Verletztbarkeiten, sozio-geografischen und rassistischen Ungerechtigkeiten sowie dem Traumapotenzial von Reproduktionsmedizin, Menschenhandel und Schwarzmarkt-Organhandel. Mittels eines empirischen, kritisch-diskursanalytischen, künstlerischen und philosophisch-theoretischen Zugangs entwickelt die interdisziplinäre Studie praktische kreative Werkzeuge für eine Pädagogik, die Würde und Integrität betont und die Menschenrechte im Alltag der betroffenen Bevölkerung unterstützt.