Download or read book Liver Disease in Children written by Frederick J. Suchy and published by Cambridge University Press. This book was released on 2007-05-07 with total page 995 pages. Available in PDF, EPUB and Kindle. Book excerpt: Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Download or read book Cystogenesis written by Jong Hoon Park and published by Springer. This book was released on 2016-10-12 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.

Download or read book Differential Diagnosis in Cytopathology Book and Online Bundle written by Paolo Gattuso and published by Cambridge University Press. This book was released on 2014-12-04 with total page 695 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated edition remains the essential text for pathologists seeking to make accurate diagnoses from the vast number of differentials.

Download or read book Pediatric Hepatology and Liver Transplantation written by Lorenzo D'Antiga and published by Springer. This book was released on 2019-04-29 with total page 817 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and transition to adult care. Key topics in the field of liver transplantation are then addressed. Examples include indications and contraindications, surgical techniques and complications, immunosuppression, in pediatric liver transplantation, acute and chronic rejection and allograft dysfunction, and CMV and EBV infection in transplant recipients, long-term graft injury and tolerance. A section on pediatric hepatology across the world includes chapters presenting the features and management of pediatric liver disease in South-America, Africa and Asia. A closing section considers what the future holds for pediatric liver disease and its management, including novel genetic testing, cell therapy and gene therapy. Pediatric Hepatology and Liver Transplantation will be of value for a range of practitioners, from residents making their first approach to pediatric liver disease through to specialists working in transplantation centers.

Download or read book Silva s Diagnostic Renal Pathology written by Xin J. Zhou and published by Cambridge University Press. This book was released on 2017-03-02 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: An algorithmic approach to interpreting renal pathology, updated in light of recent advances in understanding and new classification schemes.

Download or read book Textbook of Pediatric Gastroenterology Hepatology and Nutrition written by Stefano Guandalini and published by Springer. This book was released on 2015-09-30 with total page 889 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a comprehensive and state-of-the-art overview of the major issues specific to the field of pediatric gastroenterology, hepatology, and nutrition. The first part of the book, Gastroenterology and Nutrition, presents in a systematic way the overall scope of issues encountered by children (newborn to teenagers) suffering from disorders of the gastrointestinal tract, pancreas and/or presenting nutritional issues. These chapters are structured in logical sections to facilitate consultation and include major topics ranging from congenital disorders to gastrointestinal problems of the newborn, infectious diseases of the gastrointestinal tract, and approach to nutritional problems in the various pediatric ages. The second part of the book, Hepatology, is articulated in a series of chapters which present a comprehensive review of congenital and acquired disorders of the biliary tract and liver. This section also includes a critical analysis of available diagnostic and therapeutic procedures and future perspectives. Written by experts in the field, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition: A Comprehensive Guide to Practice constitutes a much needed, innovative resource combining updated, reliable and comprehensive information with agile consultation for a streamlined approach to the care of children with such disorders.

Download or read book Pediatric Hepatology written by William F. Balistreri and published by CRC Press. This book was released on 1990-04-01 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: Third in a series of textbooks on pediatric disease primarily based on annual seminars held at the Gant in Aspen, Colorado as part of the Aspen conference on Pediatric Diseases, directed by the Institute for Pediatric Medical Education founded in 1981.

Download or read book Textbook of Clinical Pediatrics written by H. A. Harfi and published by Springer Science & Business Media. This book was released on 2012-01-10 with total page 4213 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this classic reference offers a problem-based approach to pediatric diseases. It encompasses almost all pediatric subspecialties and covers every pediatric disease and organ system. It includes case studies and over 750 lavish illustrations.

Download or read book Pediatric Body MRI written by Edward Y. Lee and published by Springer. This book was released on 2021-06-07 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a unique, authoritative and clinically oriented text on pediatric body MRI. It is your one-step reference for current information on pediatric body MRI addressing all aspects of congenital and acquired disorders. The easy-to-navigate text is divided into 17 chapters. Each chapter is organized to comprehensively cover the latest MRI techniques, fundamental embryology and anatomy, normal development and anatomic variants, key clinical presentation, characteristic imaging findings with MRI focus, differential diagnosis and pitfalls, as well as up-to-date management and treatment. Written by internationally known pediatric radiology experts and editorial team lead by acclaimed author, Edward Y. Lee, MD, MPH, this book is an ideal guide for practicing radiologists, radiology trainees, MRI technologists as well as clinicians in other specialties who are interested in pediatric body MRI.

Download or read book Imaging of the Liver and Intra hepatic Biliary Tract written by Emilio Quaia and published by Springer Nature. This book was released on 2020-09-28 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first of two volumes that together provide a comprehensive analysis of the embryology, normal anatomy, and pathology of the liver and intrahepatic biliary tract as seen on modern diagnostic imaging techniques. In this volume, readers will find fundamental information on embryology, radiological anatomy, and anatomic variants. A thorough introduction is then provided to each imaging technique, including ultrasound, computed tomography, magnetic resonance imaging, nuclear medicine techniques, angiography, and interventional radiology. The remainder of the volume is devoted to non-tumoral pathology of the liver and intra-hepatic biliary tract. For each disease, readers will find full description of the roles of individual imaging modalities and extensive illustration of the imaging appearances. The authors are world-leading experts in the field, and the book will be an ideal reference for all members of the radiology community, from residents to experts. It will also aid clinicians during their daily practice.

Download or read book Handbook of Fetal Medicine written by Sailesh Kumar and published by Cambridge University Press. This book was released on 2010-07-01 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Fetal Medicine provides a concise and practical guide to the modern management of normal pregnancy and the at-risk fetus. Comprehensive in scope, in an easy-to-use format, the book provides guidance on a wide range of conditions, best practice management strategies and treatment options in maternal-fetal medicine. Each system-based chapter has a brief introduction on embryology and discusses the key genetic developments and relevant developmental abnormalities. The book begins by addressing genetic disorders such as Down syndrome, and goes on to consider skeletal and bodily system abnormalities. All key management points are highlighted and data on long-term outcomes are provided. This book will appeal to maternal-fetal medicine specialists, subspecialty trainees, obstetricians and midwives as a useful practical reference tool in daily practice. It is particularly suitable for trainees in Obstetrics & Gynaecology preparing for the post graduate examinations.

Download or read book Essentials of Surgical Pediatric Pathology written by Marta C. Cohen and published by Cambridge University Press. This book was released on 2015-02-05 with total page 1225 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essentials of Surgical Pediatric Pathology is a clear and practical yet comprehensive guide for trainee pediatric pathologists and non-pediatric pathologists. Each chapter corresponds to one of the main subspecialties, such as dermatopathology, head and neck pathology, and system pathology. Practical guidance is given on handling pediatric specimens and the authors highlight the ways in which common conditions present differently in adults and children. Other chapters cover conditions typical of childhood, including soft tissue tumors and blue round cell tumors. The chapters begin with a brief clinical presentation, followed by a clear macroscopical and histological description of the principal pathologies seen in children. Up-to-date genetic and immunohistochemical information is provided, and the book includes hundreds of high-quality color images. Written and edited by leading international experts in the field, this is an essential resource for trainee pediatric pathologists, as well as general pathologists who may encounter pediatric cases.

Download or read book Multiparametric Ultrasound Diagnosis of Breast Diseases written by Gennady T. Sukhikh and published by Springer. This book was released on 2018-06-08 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated book provides a comprehensive overview of the use of current ultrasound techniques, including contrast-enhanced ultrasound and ultrasonic elastography, in the diagnosis of breast disease. The advantages and pitfalls of the various imaging modalities are identified, and it is explained how combined use of the modalities – multiparametric ultrasound – aids diagnosis and in particular assists in the differentiation of benign and malignant disease. Readers will find detailed description and illustration of the imaging appearances of age-related features (including in children and adolescents), the most important benign diseases, different forms of breast cancer, mammary gland pathology in the contexts of pregnancy and female reproductive system disease, chest gland pathology in males, and recurrent and metastatic disease. In addition, ultrasound-guided breast interventions and imaging of breast implants are discussed. Specialists in ultrasound diagnostics, radiologists, oncologists, and surgeons will all find this topical book to be both interesting and helpful in daily clinical practice.

Download or read book NORD Guide to Rare Disorders written by National Organization for Rare Disorders and published by Lippincott Williams & Wilkins. This book was released on 2003 with total page 982 pages. Available in PDF, EPUB and Kindle. Book excerpt: NORD Guide to Rare Disorders is a comprehensive, practical, authoritative guide to the diagnosis and management of more than 800 rare diseases. The diseases are discussed in a uniform, easy-to-follow format--a brief description, signs and symptoms, etiology, related disorders, epidemiology, standard treatment, investigational treatment, resources, and references.The book includes a complete directory of orphan drugs, a full-color atlas of visual diagnostic signs, and a Master Resource List of support groups and helpful organizations. An index of symptoms and key words offers physicians valuable assistance in finding the information they need quickly.

Download or read book Pediatric Ultrasound written by Harriet J. Paltiel and published by Springer Nature. This book was released on 2021-09-07 with total page 1034 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential book is a unique, authoritative and clinically oriented text on pediatric ultrasound. It provides up-to-date information addressing all aspects of congenital and acquired disorders in children encountered in clinical practice. The easy-to-navigate text is divided into 20 chapters. Each chapter is organized to cover the latest ultrasound techniques, normal development and anatomy, anatomic variants, key clinical presentations, characteristic ultrasound imaging findings, differential diagnoses and relevant pitfalls. With more than 2400 images, examples of new technological developments such as contrast-enhanced ultrasound and elastography are included. Written by internationally known pediatric radiology experts and editorial team lead by acclaimed authors, Harriet J. Paltiel, MDCM and Edward Y. Lee, MD, MPH, this reference is a practical and ideal guide for radiologists, radiology trainees, ultrasound technologists as well as clinicians in other specialties with an interest in pediatric ultrasound.

Download or read book Pediatric Nephrology written by Ellis D. Avner and published by Springer Science & Business Media. This book was released on 2009-08-20 with total page 2059 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an extensive update of Pediatric Nephrology, which has become the standard reference text in the field. It is global in perspective and reflects the international group of editors, who are well-recognized experts in pediatric nephrology. Within this text, the development of kidney structure and function is followed by detailed and comprehensive chapters on all childhood kidney diseases.

Download or read book Atlas of Genodermatoses written by Ruggero Caputo and published by CRC Press. This book was released on 2005-12-12 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: A lavishly illustrated guide to almost 200 inherited diseases of the skin, hair, and nails. Each entry includes synonyms, age of onset, clinical findings, complications, course, laboratory findings, diagnosis, therapy, and key references, adding up to far more than just a collection of photographs. In addition to being a clinical primer, this is also a work of scientific research and contains the first printed description of two new syndromes. The fast-moving world of genetic research means that the latest genetic correlations, included here, render previous texts out of date. All specialists in Dermatology and Pediatrics should find this an invaluable front-line resource in the clinic.