Download or read book The Life Sciences written by and published by National Academies. This book was released on 1970-01-01 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biomedical Computing written by Joseph A. November and published by JHU Press. This book was released on 2012-06-01 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the Computer History Museum Prize of the Special Interest Group: Computers, Information, and Society Imagine biology and medicine today without computers. What would laboratory work be like if electronic databases and statistical software did not exist? Would disciplines like genomics even be feasible if we lacked the means to manage and manipulate huge volumes of digital data? How would patients fare in a world absent CT scans, programmable pacemakers, and computerized medical records? Today, computers are a critical component of almost all research in biology and medicine. Yet, just fifty years ago, the study of life was by far the least digitized field of science, its living subject matter thought too complex and dynamic to be meaningfully analyzed by logic-driven computers. In this long-overdue study, historian Joseph November explores the early attempts, in the 1950s and 1960s, to computerize biomedical research in the United States. Computers and biomedical research are now so intimately connected that it is difficult to imagine when such critical work was offline. Biomedical Computing transports readers back to such a time and investigates how computers first appeared in the research lab and doctor's office. November examines the conditions that made possible the computerization of biology—including strong technological, institutional, and political support from the National Institutes of Health—and shows not only how digital technology transformed the life sciences but also how the intersection of the two led to important developments in computer architecture and software design. The history of this phenomenon has been only vaguely understood. November's thoroughly researched and lively study makes clear for readers the motives behind computerizing the study of life and how that technology profoundly affects biomedical research today.
Download or read book Computers in Life Science Research written by William Siler and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: 45 certainty about Federal policy concern the University of Alabama cardiac in ing the support of training contribute tensive care monitoring system on "ob to these difficulties. The problems are solete 1800 computers." Another re too broad and too complex to address sponded most efficaciously pointing out here. They are difficult for both aca that it is too bad that people lose sight of demia and government, and warrant the fact that a system on which a pro the active concern of the entire research gram is developed will always be able community. to do the job; change is not indicated Dr. Robert Macey introduced to the until the system ceases to be appropri ate. conference the exciting world of model development describing an application In another vein, the question opens to the area of membrane transport. The up a wide range of problems that can be discussion of his paper exposed the prob summarized as problems in the diffusion lern the modeler has of gaining ac of computer-based technology. At this ceptance of his particular approach, but juncture biomedical computing joins all mainly it provided a taste of the intellec the rest of biomedicine. The problems of tual excitement that modeling generates diffusion of advances in health research, among both doers and observers.
Download or read book Catalyzing Inquiry at the Interface of Computing and Biology written by National Research Council and published by National Academies Press. This book was released on 2006-01-01 with total page 469 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in computer science and technology and in biology over the last several years have opened up the possibility for computing to help answer fundamental questions in biology and for biology to help with new approaches to computing. Making the most of the research opportunities at the interface of computing and biology requires the active participation of people from both fields. While past attempts have been made in this direction, circumstances today appear to be much more favorable for progress. To help take advantage of these opportunities, this study was requested of the NRC by the National Science Foundation, the Department of Defense, the National Institutes of Health, and the Department of Energy. The report provides the basis for establishing cross-disciplinary collaboration between biology and computing including an analysis of potential impediments and strategies for overcoming them. The report also presents a wealth of examples that should encourage students in the biological sciences to look for ways to enable them to be more effective users of computing in their studies.
Download or read book Data Analysis for the Life Sciences with R written by Rafael A. Irizarry and published by CRC Press. This book was released on 2016-10-04 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code that performs this analysis and connect the lines of code to the statistical and mathematical concepts explained.
Download or read book Computers in Fisheries Research written by Bernard A. Megrey and published by Springer Science & Business Media. This book was released on 2008-11-26 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of this book was published by Chapman and Hall Ltd. in 1996. The first edition contained nine chapters and, for all except one chapter, the original chapter authors agreed to update their chapter. Comparing these chapters gives the reader an idea of the development over a time span of more than 10 years between the two editions. In the preparation of the second edition we decided to add more chapters reflecting some important fields with significant contributions to present day fishery research. These are the use of internet for searching of information (Chapter 2), and the present state and use of remote sensing (Chapter 5), ecosystem modeling (Chapter 8) and visualization of data (Chapter 10). This second edition provides a valuable sampling of contemporary applications. Scientists have an opportunity to evaluate the suitability of different computer technology applications to their particular research situation thereby taking advantage of the experience of others. The chapters that follow are the fruition of this idea. The history behind this book started in 1989 when we were asked by Dr. Vidar Wespestad (previously: Alaska Fisheries Science Center, Seattle, USA) to prepare and convene a session at the 1992 World Fishery Congress in Athens, Greece on computer applications in fisheries. We agreed that the idea was a good one and the computer session in 1992 turned out to be very successful.
Download or read book Dual Use Research of Concern in the Life Sciences written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-01 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.
Download or read book Deep Learning for the Life Sciences written by Bharath Ramsundar and published by O'Reilly Media. This book was released on 2019-04-10 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Deep learning has already achieved remarkable results in many fields. Now it’s making waves throughout the sciences broadly and the life sciences in particular. This practical book teaches developers and scientists how to use deep learning for genomics, chemistry, biophysics, microscopy, medical analysis, and other fields. Ideal for practicing developers and scientists ready to apply their skills to scientific applications such as biology, genetics, and drug discovery, this book introduces several deep network primitives. You’ll follow a case study on the problem of designing new therapeutics that ties together physics, chemistry, biology, and medicine—an example that represents one of science’s greatest challenges. Learn the basics of performing machine learning on molecular data Understand why deep learning is a powerful tool for genetics and genomics Apply deep learning to understand biophysical systems Get a brief introduction to machine learning with DeepChem Use deep learning to analyze microscopic images Analyze medical scans using deep learning techniques Learn about variational autoencoders and generative adversarial networks Interpret what your model is doing and how it’s working
Download or read book Research Methods in Human Computer Interaction written by Jonathan Lazar and published by Morgan Kaufmann. This book was released on 2017-04-28 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Methods in Human-Computer Interaction is a comprehensive guide to performing research and is essential reading for both quantitative and qualitative methods. Since the first edition was published in 2009, the book has been adopted for use at leading universities around the world, including Harvard University, Carnegie-Mellon University, the University of Washington, the University of Toronto, HiOA (Norway), KTH (Sweden), Tel Aviv University (Israel), and many others. Chapters cover a broad range of topics relevant to the collection and analysis of HCI data, going beyond experimental design and surveys, to cover ethnography, diaries, physiological measurements, case studies, crowdsourcing, and other essential elements in the well-informed HCI researcher's toolkit. Continual technological evolution has led to an explosion of new techniques and a need for this updated 2nd edition, to reflect the most recent research in the field and newer trends in research methodology. This Research Methods in HCI revision contains updates throughout, including more detail on statistical tests, coding qualitative data, and data collection via mobile devices and sensors. Other new material covers performing research with children, older adults, and people with cognitive impairments. - Comprehensive and updated guide to the latest research methodologies and approaches, and now available in EPUB3 format (choose any of the ePub or Mobi formats after purchase of the eBook) - Expanded discussions of online datasets, crowdsourcing, statistical tests, coding qualitative data, laws and regulations relating to the use of human participants, and data collection via mobile devices and sensors - New material on performing research with children, older adults, and people with cognitive impairments, two new case studies from Google and Yahoo!, and techniques for expanding the influence of your research to reach non-researcher audiences, including software developers and policymakers
Download or read book Essential Computing Skills for Biologists written by Fenglou Mao and published by World Scientific Publishing Company Incorporated. This book was released on 2016-12-31 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the most important skills for anyone who wants to do quantitative analysis on biological data, especially for high-throughput omics data. Three topics are covered in this book: (1) Essential knowledge and skills necessary to use a Linux computer; (2) Write programs in Perl, and the use of BioPerl to write bioinformatics Perl programs; (3) Write programs in R, and the use of R to analyze data and generate pictures.
Download or read book Artificial Intelligence in Medicine written by David Riaño and published by Springer. This book was released on 2019-06-19 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 17th Conference on Artificial Intelligence in Medicine, AIME 2019, held in Poznan, Poland, in June 2019. The 22 revised full and 31 short papers presented were carefully reviewed and selected from 134 submissions. The papers are organized in the following topical sections: deep learning; simulation; knowledge representation; probabilistic models; behavior monitoring; clustering, natural language processing, and decision support; feature selection; image processing; general machine learning; and unsupervised learning.
Download or read book Python for the Life Sciences written by Alexander Lancaster and published by Apress. This book was released on 2019-09-27 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treat yourself to a lively, intuitive, and easy-to-follow introduction to computer programming in Python. The book was written specifically for biologists with little or no prior experience of writing code - with the goal of giving them not only a foundation in Python programming, but also the confidence and inspiration to start using Python in their own research. Virtually all of the examples in the book are drawn from across a wide spectrum of life science research, from simple biochemical calculations and sequence analysis, to modeling the dynamic interactions of genes and proteins in cells, or the drift of genes in an evolving population. Best of all, Python for the Life Sciences shows you how to implement all of these projects in Python, one of the most popular programming languages for scientific computing. If you are a life scientist interested in learning Python to jump-start your research, this is the book for you. What You'll Learn Write Python scripts to automate your lab calculations Search for important motifs in genome sequences Use object-oriented programming with Python Study mining interaction network data for patterns Review dynamic modeling of biochemical switches Who This Book Is For Life scientists with little or no programming experience, including undergraduate and graduate students, postdoctoral researchers in academia and industry, medical professionals, and teachers/lecturers. “A comprehensive introduction to using Python for computational biology... A lovely book with humor and perspective” -- John Novembre, Associate Professor of Human Genetics, University of Chicago and MacArthur Fellow “Fun, entertaining, witty and darn useful. A magical portal to the big data revolution” -- Sandro Santagata, Assistant Professor in Pathology, Harvard Medical School “Alex and Gordon’s enthusiasm for Python is contagious” -- Glenys Thomson Professor of Integrative Biology, University of California, Berkeley
Download or read book Innovations in Life Science Research written by Rajeshwar P. Sinha and published by . This book was released on 2019 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Computing Skills for Biologists written by Stefano Allesina and published by Princeton University Press. This book was released on 2019-01-15 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise introduction to key computing skills for biologists While biological data continues to grow exponentially in size and quality, many of today’s biologists are not trained adequately in the computing skills necessary for leveraging this information deluge. In Computing Skills for Biologists, Stefano Allesina and Madlen Wilmes present a valuable toolbox for the effective analysis of biological data. Based on the authors’ experiences teaching scientific computing at the University of Chicago, this textbook emphasizes the automation of repetitive tasks and the construction of pipelines for data organization, analysis, visualization, and publication. Stressing practice rather than theory, the book’s examples and exercises are drawn from actual biological data and solve cogent problems spanning the entire breadth of biological disciplines, including ecology, genetics, microbiology, and molecular biology. Beginners will benefit from the many examples explained step-by-step, while more seasoned researchers will learn how to combine tools to make biological data analysis robust and reproducible. The book uses free software and code that can be run on any platform. Computing Skills for Biologists is ideal for scientists wanting to improve their technical skills and instructors looking to teach the main computing tools essential for biology research in the twenty-first century. Excellent resource for acquiring comprehensive computing skills Both novice and experienced scientists will increase efficiency by building automated and reproducible pipelines for biological data analysis Code examples based on published data spanning the breadth of biological disciplines Detailed solutions provided for exercises in each chapter Extensive companion website
Download or read book Clinical Research Computing written by Prakash Nadkarni and published by Academic Press. This book was released on 2016-04-29 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Research Computing: A Practitioner's Handbook deals with the nuts-and-bolts of providing informatics and computing support for clinical research. The subjects that the practitioner must be aware of are not only technological and scientific, but also organizational and managerial. Therefore, the author offers case studies based on real life experiences in order to prepare the readers for the challenges they may face during their experiences either supporting clinical research or supporting electronic record systems. Clinical research computing is the application of computational methods to the broad field of clinical research. With the advent of modern digital computing, and the powerful data collection, storage, and analysis that is possible with it, it becomes more relevant to understand the technical details in order to fully seize its opportunities. - Offers case studies, based on real-life examples where possible, to engage the readers with more complex examples - Provides studies backed by technical details, e.g., schema diagrams, code snippets or algorithms illustrating particular techniques, to give the readers confidence to employ the techniques described in their own settings - Offers didactic content organization and an increasing complexity through the chapters
Download or read book Funding a Revolution written by National Research Council and published by National Academies Press. This book was released on 1999-02-11 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past 50 years have witnessed a revolution in computing and related communications technologies. The contributions of industry and university researchers to this revolution are manifest; less widely recognized is the major role the federal government played in launching the computing revolution and sustaining its momentum. Funding a Revolution examines the history of computing since World War II to elucidate the federal government's role in funding computing research, supporting the education of computer scientists and engineers, and equipping university research labs. It reviews the economic rationale for government support of research, characterizes federal support for computing research, and summarizes key historical advances in which government-sponsored research played an important role. Funding a Revolution contains a series of case studies in relational databases, the Internet, theoretical computer science, artificial intelligence, and virtual reality that demonstrate the complex interactions among government, universities, and industry that have driven the field. It offers a series of lessons that identify factors contributing to the success of the nation's computing enterprise and the government's role within it.
Download or read book Opportunities in Biology written by National Research Council and published by National Academies. This book was released on 1989-01-01 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.