Download or read book Computational Reconstruction of Missing Data in Biological Research written by Feng Bao and published by Springer Nature. This book was released on 2021-08-06 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emerging biotechnologies have significantly advanced the study of biological mechanisms. However, biological data usually contain a great amount of missing information, e.g. missing features, missing labels or missing samples, which greatly limits the extensive usage of the data. In this book, we introduce different types of biological data missing scenarios and propose machine learning models to improve the data analysis, including deep recurrent neural network recovery for feature missings, robust information theoretic learning for label missings and structure-aware rebalancing for minor sample missings. Models in the book cover the fields of imbalance learning, deep learning, recurrent neural network and statistical inference, providing a wide range of references of the integration between artificial intelligence and biology. With simulated and biological datasets, we apply approaches to a variety of biological tasks, including single-cell characterization, genome-wide association studies, medical image segmentations, and quantify the performances in a number of successful metrics. The outline of this book is as follows. In Chapter 2, we introduce the statistical recovery of missing data features; in Chapter 3, we introduce the statistical recovery of missing labels; in Chapter 4, we introduce the statistical recovery of missing data sample information; finally, in Chapter 5, we summarize the full text and outlook future directions. This book can be used as references for researchers in computational biology, bioinformatics and biostatistics. Readers are expected to have basic knowledge of statistics and machine learning.
Download or read book Computational Science ICCS 2005 written by V.S. Sunderam and published by Springer. This book was released on 2005-05-04 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Fifth International Conference on Computational Science (ICCS 2005) held in Atlanta, Georgia, USA, May 22-25, 2005 ...
Download or read book Research in Computational Molecular Biology written by Benny Chor and published by Springer. This book was released on 2012-04-13 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 16th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2012, held in Barcelona, Spain, in April 2012. The 31 revised full papers presented together with 5 keynote lectures were carefully reviewed and selected from 200 submissions. The papers feature current research in all areas of computational molecular biology, including: molecular sequence analysis; recognition of genes and regulatory elements; molecular evolution; protein structure; structural genomics; analysis of gene expression; biological networks; sequencing and genotyping technologies; drug design; probabilistic and combinatorial algorithms; systems biology; computational proteomics; structural and functional genomics; information systems for computational biology and imaging.
Download or read book Computational Intelligence in Medical Informatics written by Arpad Kelemen and published by Springer Science & Business Media. This book was released on 2008-01-03 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Informatics (MI) is an emerging interdisciplinary science. This book deals with the application of computational intelligence in MI. Addressing the various issues of medical informatics using different computational intelligence approaches is the novelty of this edited volume. This volume comprises of 15 chapters selected on the basis of fundamental ideas/concepts including an introductory chapter giving the fundamental definitions and some important research challenges.
Download or read book Research in Computational Molecular Biology written by Russell Schwartz and published by Springer Nature. This book was released on 2020-04-20 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 24th Annual Conference on Research in Computational Molecular Biology, RECOMB 2020, held in Padua, Italy, in May 2020. The 13 regular and 24 short papers presented were carefully reviewed and selected from 206 submissions. The papers report on original research in all areas of computational molecular biology and bioinformatics.
Download or read book Computational Phylogenetics written by Tandy Warnow and published by Cambridge University Press. This book was released on 2018 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the foundations of phylogeny estimation and technical material enabling researchers to develop improved computational methods.
Download or read book Algorithms in Bioinformatics written by Steven L. Salzberg and published by Springer Science & Business Media. This book was released on 2009-08-28 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: These proceedings contain papers from the 2009 Workshop on Algorithms in Bioinformatics (WABI), held at the University of Pennsylvania in Philadelphia, Pennsylvania during September 12–13, 2009. WABI 2009 was the ninth annual conference in this series, which focuses on novel algorithms that address imp- tantproblemsingenomics,molecularbiology,andevolution.Theconference- phasizes research that describes computationally e?cient algorithms and data structures that have been implemented and tested in simulations and on real data. WABI is sponsored by the European Association for Theoretical C- puter Science (EATCS) and the International Society for Computational Bi- ogy (ISCB). WABI 2009 was supported by the Penn Genome Frontiers Institute and the Penn Center for Bioinformatics at the University of Pennsylvania. For the 2009 conference, 90 full papers were submitted for review by the Program Committee, and from this strong ?eld of submissions, 34 papers were chosen for presentation at the conference and publication in the proceedings. The ?nal programcovered a wide range of topics including gene interaction n- works, molecular phylogeny, RNA and protein structure, and genome evolution.
Download or read book Research in Computational Molecular Biology written by Itsik Pe'er and published by Springer Nature. This book was released on 2022-05-11 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 26th Annual Conference on Research in Computational Molecular Biology, RECOMB 2022, held in San Diego, CA, USA in May 2022. The 17 regular and 23 short papers presented were carefully reviewed and selected from 188 submissions. The papers report on original research in all areas of computational molecular biology and bioinformatics.
Download or read book Intelligent Computing and Optimization written by Pandian Vasant and published by Springer Nature. This book was released on 2021-02-07 with total page 1332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Third edition of International Conference on Intelligent Computing and Optimization and as a premium fruit, this book, pursue to gather research leaders, experts and scientists on Intelligent Computing and Optimization to share knowledge, experience and current research achievements. Conference and book provide a unique opportunity for the global community to interact and share novel research results, explorations and innovations among colleagues and friends. This book is published by SPRINGER, Advances in Intelligent Systems and Computing. Ca. 100 authors submitted full papers to ICO’2020. That global representation demonstrates the growing interest of the research community here. The book covers innovative and creative research on sustainability, smart cities, meta-heuristics optimization, cyber-security, block chain, big data analytics, IoTs, renewable energy, artificial intelligence, Industry 4.0, modeling and simulation. We editors thank all authors and reviewers for their important service. Best high-quality papers have been selected by the International PC for our premium series with SPRINGER.
Download or read book Handbook of Computational Molecular Biology written by Srinivas Aluru and published by CRC Press. This book was released on 2005-12-21 with total page 1108 pages. Available in PDF, EPUB and Kindle. Book excerpt: The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young field, but has seen rapid growth and advancement over the past few decades. Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology of
Download or read book Research in Computational Molecular Biology written by Satoru Miyano and published by Springer. This book was released on 2005-05-04 with total page 646 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains the papers presented at the 9th Annual International Conference on Research in Computational Molecular Biology (RECOMB 2005), which was held in Cambridge, Massachusetts, on May 14–18, 2005. The RECOMB conference series was started in 1997 by Sorin Istrail, Pavel Pevzner and Michael Waterman. The list of previous meetings is shown below in the s- tion “Previous RECOMB Meetings. ” RECOMB 2005 was hosted by the Broad Institute of MIT and Harvard, and Boston University’s Center for Advanced - nomic Technology, and was excellently organized by the Organizing Committee Co-chairs Jill Mesirov and Simon Kasif. This year, 217 papers were submitted, of which the Program Committee - lected 39 for presentation at the meeting and inclusion in this proceedings. Each submission was refereed by at least three members of the Program Committee. After the completion of the referees’ reports, an extensive Web-based discussion took place for making decisions. From RECOMB 2005, the Steering Committee decided to publish the proceedings as a volume of Lecture Notes in Bioinf- matics (LNBI) for which the founders of RECOMB are also the editors. The prominent volume number LNBI 3500 was assigned to this proceedings. The RECOMB conference series is closely associated with the Journal of Compu- tional Biology which traditionally publishes special issues devoted to presenting full versions of selected conference papers. The RECOMB Program Committee consistedof42members,aslistedonaseparatepage. Iwouldliketothank the RECOMB 2005 Program Committee members for their dedication and hard work.
Download or read book Research in Computational Molecular Biology written by Alberto Apostolico and published by Springer Science & Business Media. This book was released on 2006-03-22 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 10th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2006, held in Venice, Italy in April 2006. The 40 revised full papers presented together with abstracts of 7 keynote talks were carefully reviewed and selected from 212 submissions. As the top conference in computational molecular biology, RECOMB addresses all current issues in algorithmic, theoretical, and experimental bioinformatics.
Download or read book Bioinformatics Research and Applications written by Mark Borodovsky and published by Springer Science & Business Media. This book was released on 2010-05-06 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume constitutes the refereed proceedings of the 6th International Symposium on Bioinformatics Research and Applications, ISBRA 2010, held in Storrs, CT, USA, in May 2010. The 20 revised full papers and 6 invited talks presented were carefully reviewed and selected out of 57 submissions. Topics presented span all areas of bioinformatics and computational biology, including the development of experimental or commercial systems.
Download or read book Reconstruction of Gene Regulatory Networks Using Biological Domain Knowledge written by Akther Shermin and published by . This book was released on 2012 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: High throughput technologies such as microarrays generate an enormous amount of genomic data at the cellular level. The computational reconstruction of gene regulatory networks (GRN) from this abundance of data has become a major area of research in systems and computational biology. However, the reconstruction task suffers from two major challenges: the excessive computational complexity and the low accuracy of the estimated networks. Literature of related works suggests the utilization of domain knowledge in addressing these challenges. The main interest of this thesis is to study the effectiveness of incorporating biological knowledge and other sources of biological data in the computational reconstruction of GRN. -- The thesis starts with the identification of several key features of gene regulation that are used by the transcriptional regulators and employs that knowledge to restrict the number of possible regulators for each gene. We choose Dynamic Bayesian Network for the computational reconstruction of the GRN. The thesis then explores the co-regulation of genes and the potency of integrating multiple sources of biological data in the reconstruction task. Through the analysis of both real and synthetic data, this thesis also quantifies to what extent the computation time and reconstruction accuracy of the model has been improved. -- The comprehensive performance and scalability analysis of various GRN models demonstrate that the employment of biological features can convincingly reduce the computational complexity of the model. Moreover, the integration of other sources of biological data makes the model computationally efficient and estimates networks with improved accuracy. Most importantly, such integration results in a scalable model; that is, the model estimates networks including thousand genes while preserving its level of performance.
Download or read book Advances in Computational Intelligence written by Ildar Batyrshin and published by Springer. This book was released on 2013-03-21 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two-volume set LNAI 7629 and LNAI 7630 constitutes the refereed proceedings of the 11th Mexican International Conference on Artificial Intelligence, MICAI 2012, held in San Luis Potosí, Mexico, in October/November 2012. The 80 revised papers presented were carefully reviewed and selected from 224 submissions. The second volume includes 40 papers focusing on soft computing. The papers are organized in the following topical sections: natural language processing; evolutionary and nature-inspired metaheuristic algorithms; neural networks and hybrid intelligent systems; fuzzy systems and probabilistic models in decision making.
Download or read book Research in Computational Molecular Biology written by Roded Sharan and published by Springer. This book was released on 2014-02-28 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 18th Annual International Conference on Research in Computational Molecular Biology, RECOMB 2014, held in Pittsburgh, PA, USA, in April 2014. The 35 extended abstracts were carefully reviewed and selected from 154 submissions. They report on original research in all areas of computational molecular biology and bioinformatics.
Download or read book Animal Genomics written by Bhanu P. Chowdhary and published by S. Karger AG (Switzerland). This book was released on 2003 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides an update on the current status of gene maps in different livestock and pet/companion animal species. The findings summarized in species specific commentaries and original articles testify the rapid advances made in the field of animal genomics. Of significant interest is the fact that current investigations are providing headways for two important and exciting research fronts: targeted high-resolution mapping leading to the application of genomic information in addressing questions of economic and biological significance in animals, and the initiation of whole genome sequencing projects for some of the animal species. Like in humans and mice, this will set the stage for a new level of research and real time complex analysis of the genomes of these species. Animal Genomics signifies the beginning of a new era in this field and celebrates the achievements of the past 20 years of genomics research. It will be of special interest to researchers involved in genome analysis - both gross chromosomal as well as molecular - in various animal species, and to comparative and evolutionary geneticists.
