Download or read book Computational Modeling of Powder Compaction Processes written by Amir R. Khoei and published by . This book was released on 2003 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book A Mesoscopic Approach Towards Modeling of Compaction Process in Powder Metallurgy written by Shlok Sundaresh and published by . This book was released on 2014 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational modeling of powder metallurgy process is a challenging task. Critical defect issues like cracking at prior particle boundaries, porosity, etc. arising during manufacturing of powder metallurgy components need to be addressed and well understood from a fundamental standpoint. Experimental analysis of powder metallurgy is a time consuming and expensive process as replicating such critical defects is difficult and can be done only by trial and error techniques. Thus, the main focus of this work is on powder compaction modeling as powder compaction is a critical step in the manufacturing process. Various computational models exist for powder compaction either from a macroscopic/phenomenological aspect or a micromechanical aspect. This work provides an advanced computational framework for modeling powder compaction process using a mescoscopic modeling approach that links the phenomenological modeling to microscopic modeling. The fundamental mechanisms and true behavior of the powder during compaction have been captured through this approach. Effect of powder size, distribution and contact conditions between powder particles during compaction has been quantified through the mesoscopic compaction model. Representative volume elements (RVEs) for different stress states within the powder component have also been addressed.

Download or read book Modelling of Powder Die Compaction written by Peter R. Brewin and published by Springer Science & Business Media. This book was released on 2007-09-26 with total page 341 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manufacture of components from powders frequently requires a compaction step. Modelling of Powder Die Compaction presents a number of case studies that have been developed to test compaction models. It will be bought by researchers involved in developing models of powder compaction as well as by those working in industry, either using powder compaction to make products or using products made by powder compaction.

Download or read book Recent Developments in Computer Modeling of Powder Metallurgy Processes written by Antonios Zavaliangos and published by IOS Press. This book was released on 2001 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains 25 papers from the NATO Advanced Research Workshop on Recent Advances of Computer Modeling of Powder Metallurgy Processes. The papers address cold compaction, sintering, high-temperature compaction, processing modeling, and processes and materials. The integration of mechanical and physical aspects of P/M processes is emphasized. Contributors include researchers from Europe, the United States, Korea, and Japan. Author index only. c. Book News Inc

Download or read book Computational Plasticity in Powder Forming Processes written by Amir Khoei and published by Elsevier. This book was released on 2010-07-07 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: The powder forming process is an extremely effective method of manufacturing structural metal components with high-dimensional accuracy on a mass production basis. The process is applicable to nearly all industry sectors. It offers competitive engineering solutions in terms of technical performance and manufacturing costs. For these reasons, powder metallurgy is developing faster than other metal forming technology. Computational Plasticity in Powder Forming Proceses takes a specific look at the application of computer-aided engineering in modern powder forming technologies, with particular attention given to the Finite Element Method (FEM). FEM analysis provides detailed information on conditions within the processed material, which is often more complete than can be obtained even from elaborate physical experiments, and the numerical simulation makes it possible to examine a range of designs, or operating conditions economically.* Describes the mechanical behavior of powder materials using classical and modern constitutive theories.* Devoted to the application of adaptive FEM strategy in the analysis of powder forming processes.* 2D and 3D numerical modeling of powder forming processes are presented, using advanced plasticity models.

Download or read book Process Modeling in Powder Metallurgy Particulate Materials written by and published by . This book was released on 2002 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Modelling of Powder Die Compaction written by Peter R. Brewin and published by Springer. This book was released on 2007-10-02 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manufacture of components from powders frequently requires a compaction step. Modelling of Powder Die Compaction presents a number of case studies that have been developed to test compaction models. It will be bought by researchers involved in developing models of powder compaction as well as by those working in industry, either using powder compaction to make products or using products made by powder compaction.

Download or read book Towards an Improved Understanding of Strength and Damage in Cold Compacted Powders written by Sean Garner and published by . This book was released on 2017 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The compaction of fine powders offers an attractive means of creating engineered materials; however, there are often difficulties associated with producing compacts with acceptable properties. For example, failures including lamination or capping may occur during compaction and post-compaction processes if a certain level of mechanical strength is not met. Often times, a clear understanding of the cause of the issues leading to inadequate strength is lacking, thus making it difficult to mitigate the potential for failures. There is a strong interest in the availability of tools capable of providing a deeper understanding of the mechanisms responsible for the creation of compacts with adequate strength, as well as tools that can address the criticality of potential defects, and the effect these defects have on final compact properties. The current work focuses on the following: investigating and analyzing crack formation, the development of strength in the powder compaction process, and the generation of relevant predictive models via computational modeling that will allow for process optimization. In an effort to identify the origin and the evolution of damage during the compaction/ejection cycle of powder compacts, an experimental study that compares compacts in straight and tapered dies was performed. Analysis of the presence and growth of microcracks was carried out using x-ray tomography and environmental scanning electron microscopy. The results show the presence of internal microcracks at high relative densities, and microcracks on the surface of the compacts. Parts compacted in tapered dies exhibited microcracks with smaller crack tip openings and had a higher axial strength than those made in a straight die. These experimental observations, together with the ideas of damage generation under compressive stresses, as well as finite element analysis of the stress field in the compact as it exits from the die, confirmed the hypothesis that a two-step mechanism was responsible for damage generation in powder compacts. First, microcracking occurs during unloading within the die at high pressures and subsequently surface cracks grow under the localized stresses as the compact emerges from the die. To further elucidate the behavior of powders in the powder compaction process and the effects that the discrete nature of damage had on strength, this work considered the discrete element method (DEM). For powders compacted to high density, it is crucial that the force-displacement behavior of contacting particles is adequately captured in order to make proper predictions related to damage and strength in compacted components. A new adhesive, elastoplastic contact model, which describes the force-displacement behavior of contacting particles compacted to high density, was introduced and implemented in the DEM. A methodology was developed for the calibration of the model parameters of the proposed model from macroscopic experimental results. This was achieved by the use of statistical design-of-experiments (DOE) and parameter optimization techniques. The proposed DEM contact model was used to assess the ability of the DEM to predict damage and the effect that damage has on strength. A validation study was conducted to assess the ability of the proposed model to adequately predict behavior of powders compacted to high density. DEM simulations of powder compacted in straight and tapered dies were performed. The validation study performed showed excellent agreement with experimental finding for the unloading and ejection of straight and tapered die compacts.

Download or read book Predictive Modeling of Pharmaceutical Unit Operations written by Preetanshu Pandey and published by Woodhead Publishing. This book was released on 2016-09-26 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of modeling and simulation tools is rapidly gaining prominence in the pharmaceutical industry covering a wide range of applications. This book focuses on modeling and simulation tools as they pertain to drug product manufacturing processes, although similar principles and tools may apply to many other areas. Modeling tools can improve fundamental process understanding and provide valuable insights into the manufacturing processes, which can result in significant process improvements and cost savings. With FDA mandating the use of Quality by Design (QbD) principles during manufacturing, reliable modeling techniques can help to alleviate the costs associated with such efforts, and be used to create in silico formulation and process design space. This book is geared toward detailing modeling techniques that are utilized for the various unit operations during drug product manufacturing. By way of examples that include case studies, various modeling principles are explained for the nonexpert end users. A discussion on the role of modeling in quality risk management for manufacturing and application of modeling for continuous manufacturing and biologics is also included. - Explains the commonly used modeling and simulation tools - Details the modeling of various unit operations commonly utilized in solid dosage drug product manufacturing - Practical examples of the application of modeling tools through case studies - Discussion of modeling techniques used for a risk-based approach to regulatory filings - Explores the usage of modeling in upcoming areas such as continuous manufacturing and biologics manufacturingBullet points

Download or read book Advanced Computational Materials Modeling written by Miguel Vaz Junior and published by John Wiley & Sons. This book was released on 2011-09-22 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: With its discussion of strategies for modeling complex materials using new numerical techniques, mainly those based on the finite element method, this monograph covers a range of topics including computational plasticity, multi-scale formulations, optimization and parameter identification, damage mechanics and nonlinear finite elements.

Download or read book Sintering of Advanced Materials written by Zhigang Zak Fang and published by Elsevier. This book was released on 2010-09-27 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sintering is a method for manufacturing components from ceramic or metal powders by heating the powder until the particles adhere to form the component required. The resulting products are characterised by an enhanced density and strength, and are used in a wide range of industries. Sintering of advanced materials: fundamentals and processes reviews important developments in this technology and its applicationsPart one discusses the fundamentals of sintering with chapters on topics such as the thermodynamics of sintering, kinetics and mechanisms of densification, the kinetics of microstructural change and liquid phase sintering. Part two reviews advanced sintering processes including atmospheric sintering, vacuum sintering, microwave sintering, field/current assisted sintering and photonic sintering. Finally, Part three covers sintering of aluminium, titanium and their alloys, refractory metals, ultrahard materials, thin films, ultrafine and nanosized particles for advanced materials.With its distinguished editor and international team of contributors, Sintering of advanced materials: fundamentals and processes reviews the latest advances in sintering and is a standard reference for researchers and engineers involved in the processing of ceramics, powder metallurgy, net-shape manufacturing and those using advanced materials in such sectors as electronics, automotive and aerospace engineering. - Explores the thermodynamics of sintering including sinter bonding and densification - Chapters review a variety of sintering methods including atmosphere, vacuum, liquid phase and microwave sintering - Discusses sintering of a variety of materials featuring refractory metals, super hard materials and functionally graded materials

Download or read book Computer Aided Simulation of Metal Powder Die Compaction Process written by Ashoka G. K. Jinka and published by . This book was released on 1993 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemical Engineering in the Pharmaceutical Industry written by Mary T. am Ende and published by John Wiley & Sons. This book was released on 2019-04-09 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.

Download or read book Advances in Powder Metallurgy written by Isaac Chang and published by Elsevier. This book was released on 2013-08-31 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: Powder metallurgy (PM) is a popular metal forming technology used to produce dense and precision components. Different powder and component forming routes can be used to create an end product with specific properties for a particular application or industry. Advances in powder metallurgy explores a range of materials and techniques used for powder metallurgy and the use of this technology across a variety of application areas. Part one discusses the forming and shaping of metal powders and includes chapters on atomisation techniques, electrolysis and plasma synthesis of metallic nanopowders. Part two goes on to highlight specific materials and their properties including advanced powdered steel alloys, porous metals and titanium alloys. Part three reviews the manufacture and densification of PM components and explores joining techniques, process optimisation in powder component manufacturing and non-destructive evaluation of PM parts. Finally, part four focusses on the applications of PM in the automotive industry and the use of PM in the production of cutting tools and biomaterials. Advances in powder metallurgy is a standard reference for structural engineers and component manufacturers in the metal forming industry, professionals working in industries that use PM components and academics with a research interest in the field. Discusses the forming and shaping of metal powders and includes chapters on atomisation techniques Highlights specific materials and their properties including advanced powdered steel alloys, porous metals and titanium alloys Reviews the manufacture and densification of PM components and explores joining techniques

Download or read book Rock Mechanics and Rock Engineering From the Past to the Future written by Reşat Ulusay and published by CRC Press. This book was released on 2016-11-18 with total page 2044 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rock Mechanics and Rock Engineering: From the Past to the Future contains the contributions presented at EUROCK2016, the 2016 International Symposium of the International Society for Rock Mechanics (ISRM 2016, Ürgüp, Cappadocia Region, Turkey, 29-31 August 2016). The contributions cover almost all aspects of rock mechanics and rock engineering from theories to engineering practices, emphasizing the future direction of rock engineering technologies. The 204 accepted papers and eight keynote papers, are grouped into several main sections: - Fundamental rock mechanics - Rock properties and experimental rock mechanics - Analytical and numerical methods in rock engineering - Stability of slopes in civil and mining engineering - Design methodologies and analysis - Rock dynamics, rock mechanics and rock engineering at historical sites and monuments - Underground excavations in civil and mining engineering - Coupled processes in rock mass for underground storage and waste disposal - Rock mass characterization - Petroleum geomechanics - Carbon dioxide sequestration - Instrumentation-monitoring in rock engineering and back analysis - Risk management, and - the 2016 Rocha Medal Lecture and the 2016 Franklin Lecture Rock Mechanics and Rock Engineering: From the Past to the Future will be of interest to researchers and professionals involved in the various branches of rock mechanics and rock engineering. EUROCK 2016, organized by the Turkish National Society for Rock Mechanics, is a continuation of the successful series of ISRM symposia in Europe, which began in 1992 in Chester, UK.

Download or read book Computational Methods for the Explosive and Impact Compaction of Powders written by R. F. Benck and published by . This book was released on 1985 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt: THe effects of computational cell size and slide line routines upon TROTT computer code simulations of explosive and impact powder densifications were determined. A 30 by 40 grid of quadrilateral cells was computationally adequate to describe the systems under study and the presence of a slide line did not appreciably affect the final calculated powder density. Keywords include: Powder compaction; Plate impact; Powder densification; Computer Simulation.

Download or read book How to Design and Implement Powder to Tablet Continuous Manufacturing Systems written by Fernando Muzzio and published by Elsevier. This book was released on 2022-04 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to Design and Implement Powder-to-Tablet Continuous Manufacturing Systems provides a comprehensive overview on the considerations necessary for the design of continuous pharmaceutical manufacturing processes. The book covers both the theory and design of continuous processing of associated unit operations, along with their characterization and control. In addition, it discusses practical insights and strategies that the editor and chapter authors have learned. Chapters cover Process Analytical Technology (PAT) tools and the application of PAT data to enable distributed process control. With numerous case studies throughout, this valuable guide is ideal for those engaged in, or learning about, continuous processing in pharmaceutical manufacturing. Discusses the development of strategy blueprints in the design of continuous processes Shows how to create process flowsheet models from individual unit operation models Includes a chapter on characterization methods for materials, the use of statistical methods to analyze material property data, and the use of material databases Covers the evolving regulatory expectations for continuous manufacturing Provides readers with ways to more effectively navigate these expectations