Download or read book Comparison and Optimization of Breast Tomosynthesis Imaging Configurations Based on Computer Simulation and Analysis written by Linlin Cong and published by . This book was released on 2012 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Objective: Breast cancer is one of the most worldwide cancers among women and in United States it is also the second leading cause of cancer related death among women. The earlier breast cancer is detected, the better the outcome of treatment will be. So early detect technique for breast cancer is crucial. However traditional mammography as a standard and important detection technique has its own disadvantage, like motion blur with X-tube movement and only 2D information offered. But Tomosynthesis as an alternative breast cancer detection technique can overcome these disadvantages effectively. That is the reason why more and more academic concerns are put on Tomosynthesis. This paper is to research the effects of different X-tube distributions for the reconstructed images quality, expecting to offer a reference to design imaging configuration for Tomosynthesis. The reconstructed algorithm used here is maximum Likelihood Expectation Maximization (MLEM) algorithm, considering the image quality reconstructed by MLEM is the best with regards to our simulated imaging system.
Download or read book Image Reconstruction and Imaging Configuration Optimization with a Novel Nanotechnology Enabled Breast Tomosynthesis Multi beam X ray System written by Weihua Zhou and published by . This book was released on 2012 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital breast tomosynthesis is a new technology that provides three-dimensional information of the breast and makes it possible to distinguish the cancer from overlying breast tissues. We are dedicated to optimizing image reconstruction and imaging configuration for a new multi-beam parallel digital breast tomosynthesis prototype system. Four methodologies were employed to optimize the reconstruction algorithms and different imaging configurations for the prototype system. A linear tomosynthesis imaging analysis tool was used to investigate blurring-out reconstruction algorithms. Computer simulations of sphere and wire objects aimed at the performance of out-of-plane artifact removal. A frequency-domain-based methodology, relative NEQ(f) analysis, was investigated to evaluate the overall system performance based on the propagation of signal and noise. Conclusions were made to determine the optimal image reconstruction algorithm and imaging configuration of this new multi-beam parallel digital breast tomosynthesis prototype system for better image quality and system performance.
Download or read book A Framework for Flexible Comparison and Optimization of X ray Digital Tomosynthesis written by Frank A. Smith and published by . This book was released on 2019 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Digital tomosynthesis is a novel three-dimensional imaging technology that utilizes limited number of X-ray projection images to improve the diagnosis and detection of lesions. In recent years, tomosynthesis has been used in a variety of clinical applications such as dental imaging, angiography, chest imaging, bone imaging, and breast imaging. The goal of our research is to develop a framework to enable flexible optimization and comparison of image reconstruction and imaging configurations. We developed a software framework for simulation comparison and optimization of imaging configurations that allows flexibility of X-ray parameters, detector parameters, imaging configurations, and reconstruction algorithms. Maximum likelihood expectation maximization (MLEM) algorithm is investigated for various imaging configurations based on multi-beam stationary breast tomosynthesis imaging parameters. Experiments based on different image configurations shows that our simulation combined with the MLEM algorithm can provide three-dimensional information with good image quality and has great potential to improve digital breast tomosynthesis technology. Impulse response is used to evaluate the performance of each configuration. Conclusions were made to determine the optimal image reconstruction based on the imaging configurations and associated x-ray and detector parameters.
Download or read book Tomographic Image Reconstruction written by Shiya Xu and published by . This book was released on 2014 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Conventional 2D mammography was the most effective approach to detecting early stage breast cancer in the past decades of years. Tomosynthetic breast imaging is a potentially more valuable 3D technique for breast cancer detection. The limitations of current tomosynthesis systems include a longer scanning time than a conventional digital X-ray modality and a low spatial resolution due to the movement of the single X-ray source. Dr.Otto Zhou's group proposed the concept of stationary digital breast tomosynthesis (s-DBT) using a Carbon Nano-Tube (CNT) based X-ray source array. Instead of mechanically moving a single X-ray tube, s-DBT applies a stationary X-ray source array, which generates X-ray beams from different view angles by electronically activating the individual source prepositioned at the corresponding view angle, therefore eliminating the focal spot motion blurring from sources. The scanning speed is determined only by the detector readout time and the number of sources regardless of the angular coverage spans, such that the blur from patient's motion can be reduced due to the quick scan. S-DBT is potentially a promising modality to improve the early breast cancer detection by providing decent image quality with fast scan and low radiation dose. DBT system acquires a limited number of noisy 2D projections over a limited angular range and then mathematically reconstructs a 3D breast. 3D reconstruction is faced with the challenges of cone-beam and flat-panel geometry, highly incomplete sampling and huge reconstructed volume. In this research, we investigated several representative reconstruction methods such as Filtered backprojection method (FBP), Simultaneous algebraic reconstruction technique (SART) and Maximum likelihood (ML). We also compared our proposed statistical iterative reconstruction (IR) with particular prior and computational technique to these representative methods. Of all available reconstruction methods in this research, our proposed statistical IR appears particularly promising since it provides the flexibility of accurate physical noise modeling and geometric system description. In the following chapters, we present multiple key techniques of statistical IR to tomosynthesis imaging data to demonstrate significant image quality improvement over conventional techniques. These techniques include the physical modeling with a local voxel-pair based prior with the flexibility in its parameters to fine-tune image quality, the pre-computed parameter κ incorporated with the prior to remove the data dependence and to achieve a predictable resolution property, an effective ray-driven technique to compute the forward and backprojection and an over-sampled ray-driven method to perform high resolution reconstruction with a practical region of interest (ROI) technique. In addition, to solve the estimation problem with a fast computation, we also present a semi-quantitative method to optimize the relaxation parameter in a relaxed order-subsets framework and an optimization transfer based algorithm framework which potentially allows less iterations to achieve an acceptable convergence. The phantom data is acquired with the s-DBT prototype system to assess the performance of these particular techniques and compare our proposed method to those representatives. The value of IR is demonstrated in improving the detectability of low contrast and tiny micro-calcification, in reducing cross plane artifacts, in improving resolution and lowering noise in reconstructed images. In particular, noise power spectrum analysis (NPS) indicates a superior noise spectral property of our proposed statistical IR, especially in the high frequency range. With the decent noise property, statistical IR also provides a remarkable reconstruction MTF in general and in different areas within a focus plane. Although computational load remains a significant challenge for practical development, combined with the advancing computational techniques such as graphic computing, the superior image quality provided by statistical IR will be realized to benefit the diagnostics in real clinical applications.
Download or read book Optimization of Breast Tomosynthesis written by Hannie Förnvik and published by . This book was released on 2018 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Modeling Digital Breast Tomosynthesis Imaging Systems for Optimization Studies written by Beverly Amy Lau and published by . This book was released on 2012 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this dissertation was to design the framework for a computer simulation of tomosynthesis that would produce images that are sensitive to changes in acquisition parameters, so an optimization study would be feasible.
Download or read book Physics of Mammographic Imaging written by Mia K. Markey and published by Taylor & Francis. This book was released on 2012-11-09 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the increasing number of digital mammograms and the advent of new kinds of three-dimensional x-ray and other forms of medical imaging, mammography is undergoing a dramatic change. To meet their responsibilities, medical physicists must constantly renew their knowledge of advances in medical imaging or radiation therapy, and must be prepared
Download or read book Tomosynthesis Imaging written by Ingrid Reiser and published by Taylor & Francis. This book was released on 2016-04-19 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: An innovative, three-dimensional x-ray imaging technique that enhances projection radiography by adding depth resolution, Tomosynthesis Imaging explores tomosynthesis, an emerging limited-angle tomographic imaging technology that is being considered for use in a range of clinical applications, and is currently being used for breast cancer screening
Download or read book Clinical Breast Tomosynthesis written by Lonie R. Salkowski and published by Thieme. This book was released on 2017-08-03 with total page 2123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Case studies provide a stellar resource for mastering clinical breast tomosynthesis technology Digital breast tomosynthesis (DBT), popularly called "3D mammography" is a state-of-the-art breast imaging technology that provides the ability to view inside the breast, layer by layer. Advantages of DBT include elimination of superimposed tissue, improved detection of otherwise hidden lesions, and significantly higher cancer detection rates compared to conventional mammography. Although it is increasingly being implemented in imaging centers, hands-on clinical learning tools have been lacking - until now. Written by renowned breast imaging specialists, this multimedia textbook is the most definitive DBT reference available. The first section is dedicated to DBT fundamentals, including physics, reconstruction methods, acquisition parameters, and patient dose and data size considerations. The next two sections are case-based clinical practice presentations, organized by DBT screening and diagnostic components. Key Features The use of 3D breast imaging to detect and differentiate malignancies from normal and benign findings 100 case studies include pertinent clinical information, introductory images, and findings labeled on subsequent images with BI-RADS terminology Full field digital mammography and/or synthetic 2D mammogram images included in all case studies mirror what is typically encountered in DBT breast-imaging programs Clinical pearls on navigating the technology, interpreting images, making diagnoses, and decisions regarding follow-up studies Accompanying online videos further elucidate the still images This remarkable, interactive reference is a must-have for trainee and practicing radiologists and will also benefit mammography technicians. The detailed case studies and videos demonstrate the full utility of DBT as a screening and diagnostic technology in context with mammography, ultrasound, and MRI of the breast.
Download or read book Breast Imaging written by Anders Tingberg and published by Springer. This book was released on 2016-06-16 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 13th International Workshop on Breast Imaging, IWDM 2016, held in Malmö, Sweden, in June 2016. The 35 revised full papers and 50 revised poster papers presented together with 6 invited talks were carefully reviewed and selected from 89 submissions. The papers are organized in topical sections on screening; CAD; mammography, tomosynthesis, and breast CT; novel technology; density assessment and tissue analysis; dose and classification; image processing, CAD, breast density, and new technology; contrast-enhanced imaging; phase contrast breast imaging; simulations and virtual clinical trials.
Download or read book Breast Imaging written by Andrew D.A. Maidment and published by Springer. This book was released on 2012-07-13 with total page 804 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 11th International Workshop on Digital Mammography, IWDM 2012, held in Philadelphia, PA, USA, in July 2012. The 42 revised full papers and 58 revised poster papers presented were carefully reviewed and selected from numerous initial submissions. The papers are organized in topical sections on contrast-enhancing imaging, digital mammography methods, tomosynthesis system design, tomosynthesis - image quality and dose, clinical tomosynthesis, functional breast imaging, breast computed tomography, computer-aided diagnosis and image processing, tomosynthesis reconstruction, and breast density.
Download or read book Digital Breast Tomosynthesis DBT Computational Analysis with Parallel Imaging Configurations to Improve Breast Cancer Detection written by Cleveland E. Rayford and published by . This book was released on 2011 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: The best way to conquer breast cancer is early detection of the disease. Research studies show that earlier detection results in the increase of life span of the affected person. A three-dimensional digital breast tomosynthesis (DBT) system has been created, which is hoped to surpass the technology of traditional mammography systems. In this research, the View Angle (VA) and number of projection images (N) were investigated and compared with parallel imaging configurations using two reconstruction algorithms, including Back Projection (BP) and Shift-And-Add (SAA). Modulation Transfer Function (MTF) analyses were conducted with both algorithms, in order to determine which method displayed better image qualities to ultimately improve the detection of breast cancer.
Download or read book Atlas of Breast Tomosynthesis written by Martin Sonnenschein and published by Springer. This book was released on 2017-06-08 with total page 558 pages. Available in PDF, EPUB and Kindle. Book excerpt: This superbly illustrated atlas of breast tomosynthesis covers all aspects and applications of the technology, which reduces tissue overlap and facilitates the recognition of small cancers. After clear explanation of basic principles of the technique, individual chapters address diagnostic criteria, indications, and use of breast tomosynthesis as a screening tool. The findings obtained in the full range of benign and malignant conditions, including postoperative changes, are then presented with the aid of a wealth of high-quality illustrations from case examples. Detailed attention is paid to the BI-RADS classification, bearing in mind the ability of tomosynthesis to reduce categorizations as BI-RADS 3 and 0, thereby decreasing the recall rate. The book concludes by examining tomosynthesis-guided interventions such as vacuum-assisted breast biopsy and galactography.
Download or read book X Ray Phase Contrast Tomography written by Luca Brombal and published by Springer Nature. This book was released on 2020-11-16 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: X-ray imaging is a corner stone of breast cancer diagnosis. By exploiting the phase shift of X-rays rather than their attenuation, phase-contrast tomography has the potential to dramatically increase the visibility of small and low contrast features, thus leading to better diagnosis. This thesis presents research on the first synchrotron-based project developing a clinical phase-contrast breast computed tomography (CT) setup at Elettra, the Italian Syncrotron Radiation Facility. This book includes a comprehensive theoretical background on propagation-based phase-contrast imaging, exploring and extending the most recent image formation models. Along with theory, many practical implementation and optimization issues, ranging from detector-specific processing to setup geometry, are tackled on the basis of a large number of experimental evidences. Most of the modelling results and data analysis have general validity, being a valuable framework for optimization of phase-contrast setups. Results obtained at synchrotron are also compared with "real world" laboratory sources: both a first-of-its-kind comparison with one of the few hospital breast CT systems and a state-of-the-art implementation of monochromatic phase-contrast micro-tomography with a conventional rotating anode source are presented. On a more general level, this work sheds a light on the importance of synchrotron-based clinical programs, which are key to trigger the long-anticipated transition of phase-contrast imaging from synchrotrons to hospitals.
Download or read book Breast Imaging written by Hiroshi Fujita and published by Springer. This book was released on 2014-06-23 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 12th International Workshop on Breast Imaging, IWDM 2014, held in Gifu City, Japan, in June/July 2014. The 24 revised full papers and 73 revised poster papers presented together with 6 invited talks were carefully reviewed and selected from 122 submissions. The papers are organized in topical sections on screening outcomes, ultrasound, breast density, imaging physics, CAD, tomosynthesis and ICT and image processing.
Download or read book Physics of Mammographic Imaging written by Mia K. Markey and published by CRC Press. This book was released on 2012-11-09 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the increasing number of digital mammograms and the advent of new kinds of three-dimensional x-ray and other forms of medical imaging, mammography is undergoing a dramatic change. To meet their responsibilities, medical physicists must constantly renew their knowledge of advances in medical imaging or radiation therapy, and must be prepared to function at the intersection of these two fields. Physics of Mammographic Imaging gives an overview on the current role and future potential of new alternatives to mammography in the context of clinical need, complementary approaches, and ongoing research. This book provides comprehensive coverage on the fundamentals of image formation, image interpretation, analysis, and modeling. It discusses the use of mammographic imaging in the detection, diagnosis, treatment planning, and monitoring of breast cancer. Expert authors give a balanced summary of core topics such as digital mammography, contrast-enhanced mammography, stereomammography, breast tomosynthesis, and breast CT. The book highlights the use of mammographic imaging with complementary breast imaging modalities such as ultrasound, MRI, and nuclear medicine techniques. It discusses critical issues such as computer-aided diagnosis, perception, and quality assurance. This is an exciting time in the development of medical imaging, with many new technologies poised to make a substantial impact on breast cancer care. This book will help researchers and students get up to speed on crucial developments and contribute to future advances in the field.
Download or read book Digital Breast Tomosynthesis written by Alberto Tagliafico and published by Springer. This book was released on 2016-05-03 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive description of the screening and clinical applications of digital breast tomosynthesis (DBT) and offers straightforward, clear guidance on use of the technique. Informative clinical cases are presented to illustrate how to take advantage of DBT in clinical practice. The importance of DBT as a diagnostic tool for both screening and diagnosis is increasing rapidly. DBT improves upon mammography by depicting breast tissue on a video clip made of cross‐sectional images reconstructed in correspondence with their mammographic planes of acquisition. DBT results in markedly reduced summation of overlapping breast tissue and offers the potential to improve mammographic breast cancer surveillance and diagnosis. This book will be an excellent practical teaching guide for beginners and a useful reference for more experienced radiologists.
