Download or read book Comparative Maternal and Epidemiologic Aspects written by James Wilson and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modification of embryonic development by genetic differences in the mother is a well-regcognized phemomenon, but little is known about the genet ics of these maternal traits or the mechanisms by which they act. To illustrate the genetic approach to the problem, examples are given of how differences in embryonic response to a teratogen can be partitioned into those resulting from differences in embryonic genotype (including the possible role of X-linked genes in producing reciprocal cross differences), maternal genotype, and cytoplasmically transmitted factors. The advantages and limitations of analysis by appropriate crosses, in utero treatments, embryo transfers, and in vitro experiments are illustrated. The numerous inbred strains of the mouse, with well-documented physiology, the recently developed recombinant inbred strains, and the existence of easily identified biochemical marker genes offer at tractive opportunities, so far largely unexploited, for causal analysis of mater nal effects on teratological responses. VII. ADDENDUM Since this chapter was written, several relevant papers have appeared. The strain difference between AI] and C57BU6] mice in frequency of cleft-palate response to cortisone was fitted to a model of normally distributed log tolerance (Biddle and Fraser, 1976). Genetic differences, both in maternal uterine environment and embryonic response, can be represented in terms of their effect on the median effective dose required for the cleft-palate re sponse. The maternal effect of AI] dams relative to C57BU6] dams caused a two-fold reduction in embryonic tolerance to cortisone-induced cleft palate.
Download or read book Comparative Maternal and Epidemiologic Aspects written by James Wilson and published by . This book was released on 2014-01-15 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book HANDBOOK OF TERATOLOGY Volume 3 Comparative Maternal and Epidemiologic Aspects written by JG WILSON (Ed) and published by . This book was released on 1977 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: VOL 1 GENERAL PRINCIPLES AND ETIOLOGY. VOL 2 MECHANISMS AND.
Download or read book Contraceptive Use and Controlled Fertility written by National Research Council and published by National Academies Press. This book was released on 1989-02-01 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: These four papers supplement the book Contraception and Reproduction: Health Consequences for Women and Children in the Developing World by bringing together data and analyses that would otherwise be difficult to obtain in a single source. The topics addressed are an analysis of the relationship between maternal mortality and changing reproductive patterns; the risks and benefits of contraception; the effects of changing reproductive patterns on infant health; and the psychosocial consequences to women of controlled fertility and contraceptive use.
Download or read book Handbook of Teratology written by James Graves Wilson and published by . This book was released on 1977 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comparative Quantification of Health Risks Sexual and reproductive health written by Majid Ezzati and published by World Health Organization. This book was released on 2004 with total page 2282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a comprehensive assessment of the scientific evidence on prevalence and the resulting health effects of a range of exposures that are know to be hazardous to human health, including childhood and maternal undernutrition, nutritional and physiological risk factors for adult health, addictive substances, sexual and reproductive health risks, and risks in the physical environments of households and communities, as well as among workers. This book is the culmination of over four years of scientific equiry and data collection, know as the comparative risk assessment (CRA) project.
Download or read book Disease Control Priorities Third Edition Volume 2 written by Robert Black and published by World Bank Publications. This book was released on 2016-04-11 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: The evaluation of reproductive, maternal, newborn, and child health (RMNCH) by the Disease Control Priorities, Third Edition (DCP3) focuses on maternal conditions, childhood illness, and malnutrition. Specifically, the chapters address acute illness and undernutrition in children, principally under age 5. It also covers maternal mortality, morbidity, stillbirth, and influences to pregnancy and pre-pregnancy. Volume 3 focuses on developments since the publication of DCP2 and will also include the transition to older childhood, in particular, the overlap and commonality with the child development volume. The DCP3 evaluation of these conditions produced three key findings: 1. There is significant difficulty in measuring the burden of key conditions such as unintended pregnancy, unsafe abortion, nonsexually transmitted infections, infertility, and violence against women. 2. Investments in the continuum of care can have significant returns for improved and equitable access, health, poverty, and health systems. 3. There is a large difference in how RMNCH conditions affect different income groups; investments in RMNCH can lessen the disparity in terms of both health and financial risk.
Download or read book Global Burden of Disease and Risk Factors written by Alan D. Lopez and published by World Bank Publications. This book was released on 2006-04-02 with total page 511 pages. Available in PDF, EPUB and Kindle. Book excerpt: Strategic health planning, the cornerstone of initiatives designed to achieve health improvement goals around the world, requires an understanding of the comparative burden of diseases and injuries, their corresponding risk factors and the likely effects of invervention options. The Global Burden of Disease framework, originally published in 1990, has been widely adopted as the preferred method for health accounting and has become the standard to guide the setting of health research priorities. This publication sets out an updated assessment of the situation, with an analysis of trends observed since 1990 and a chapter on the sensitivity of GBD estimates to various sources of uncertainty in methods and data.
Download or read book Reducing Birth Defects written by Institute of Medicine and published by National Academies Press. This book was released on 2003-10-27 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Each year more than 4 million children are born with birth defects. This book highlights the unprecedented opportunity to improve the lives of children and families in developing countries by preventing some birth defects and reducing the consequences of others. A number of developing countries with more comprehensive health care systems are making significant progress in the prevention and care of birth defects. In many other developing countries, however, policymakers have limited knowledge of the negative impact of birth defects and are largely unaware of the affordable and effective interventions available to reduce the impact of certain conditions. Reducing Birth Defects: Meeting the Challenge in the Developing World includes descriptions of successful programs and presents a plan of action to address critical gaps in the understanding, prevention, and treatment of birth defects in developing countries. This study also recommends capacity building, priority research, and institutional and global efforts to reduce the incidence and impact of birth defects in developing countries.
Download or read book Reproductive and Perinatal Epidemiology written by Michele Kiely and published by CRC Press. This book was released on 2019-06-04 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1990, Reproductive and Perinatal Epidemiology reviews topics that are central to reproductive and perinatal epidemiology, as well as the methodological issues surrounding research in maternal and child health. Important topics covered include prenatal care, Sudden Infant Death Syndrome (SIDS), epidemiology of neonatal brain hemorrhage, early pregnancy, methodological issues in drug epidemiology, environmental exposures and reproduction, and occupational exposures and reproduction. This book is essential reading for clinicians, researchers, obstetricians, pediatricians, and graduate students in public health.
Download or read book Research Procedures and Data Analysis written by James Wilson and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Communities in Action written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-04-27 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the United States, some populations suffer from far greater disparities in health than others. Those disparities are caused not only by fundamental differences in health status across segments of the population, but also because of inequities in factors that impact health status, so-called determinants of health. Only part of an individual's health status depends on his or her behavior and choice; community-wide problems like poverty, unemployment, poor education, inadequate housing, poor public transportation, interpersonal violence, and decaying neighborhoods also contribute to health inequities, as well as the historic and ongoing interplay of structures, policies, and norms that shape lives. When these factors are not optimal in a community, it does not mean they are intractable: such inequities can be mitigated by social policies that can shape health in powerful ways. Communities in Action: Pathways to Health Equity seeks to delineate the causes of and the solutions to health inequities in the United States. This report focuses on what communities can do to promote health equity, what actions are needed by the many and varied stakeholders that are part of communities or support them, as well as the root causes and structural barriers that need to be overcome.
Download or read book Handbook of Behavioral Teratology written by E.P. Riley and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 829 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was developed in response to a need in behavioral teratology for a comprehen sive set of reviews of the field's many topics brought together in a single source. This volume represents the first effort to synthesize and integrate research in the field since 1969 when Justin Joffe wrote Prenatal Determinants of Behaviour. Joffe's book became a standard reference for many years, particularly for the experimental design of animal investigations. It has become increasingly evident, however, that some aspects of design once considered inviolate have changed and become part of a more flexible approach. In current research the emphasis is on a set of prioritized, but focused, experimental ques tions rather than on designs which factor all possible variables into every experiment. Also, new design considerations have arisen over the last 15 years, not appreciated when Joffe wrote. Moreover, the sheer volume of new experimental evidence generated since 1969 has increased the content of the field several fold. These considerations made a new review and critical appraisal of the field compelling. The book is divided into four major sections. Part I contains four chapters. These chapters provide discussions of the general principles of behavioral teratogenesis, and information on the historical, governmental, and methodological contexts in which the field operates. The purpose of these chapters is to provide the framework within which the review chapters in the remainder of the book may best be understood.
Download or read book The Future of the Public s Health in the 21st Century written by Institute of Medicine and published by National Academies Press. This book was released on 2003-02-01 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: The anthrax incidents following the 9/11 terrorist attacks put the spotlight on the nation's public health agencies, placing it under an unprecedented scrutiny that added new dimensions to the complex issues considered in this report. The Future of the Public's Health in the 21st Century reaffirms the vision of Healthy People 2010, and outlines a systems approach to assuring the nation's health in practice, research, and policy. This approach focuses on joining the unique resources and perspectives of diverse sectors and entities and challenges these groups to work in a concerted, strategic way to promote and protect the public's health. Focusing on diverse partnerships as the framework for public health, the book discusses: The need for a shift from an individual to a population-based approach in practice, research, policy, and community engagement. The status of the governmental public health infrastructure and what needs to be improved, including its interface with the health care delivery system. The roles nongovernment actors, such as academia, business, local communities and the media can play in creating a healthy nation. Providing an accessible analysis, this book will be important to public health policy-makers and practitioners, business and community leaders, health advocates, educators and journalists.
Download or read book Concepts of Epidemiology written by Raj S. Bhopal and published by Oxford University Press. This book was released on 2016 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: First edition published in 2002. Second edition published in 2008.
Download or read book Chemical Hazards to Human Reproduction written by and published by . This book was released on 1981 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Her Lifetime written by Committee to Study Female Morbidity and Mortality in Sub-Saharan Africa and published by National Academies Press. This book was released on 1996-03-20 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relative lack of information on determinants of disease, disability, and death at major stages of a woman's lifespan and the excess morbidity and premature mortality that this engenders has important adverse social and economic ramifications, not only for Sub-Saharan Africa, but also for other regions of the world as well. Women bear much of the weight of world production in both traditional and modern industries. In Sub-Saharan Africa, for example, women contribute approximately 60 to 80 percent of agricultural labor. Worldwide, it is estimated that women are the sole supporters in 18 to 30 percent of all families, and that their financial contribution in the remainder of families is substantial and often crucial. This book provides a solid documentary base that can be used to develop an agenda to guide research and health policy formulation on female health--both for Sub-Saharan Africa and for other regions of the developing world. This book could also help facilitate ongoing, collaboration between African researchers on women's health and their U.S. colleagues. Chapters cover such topics as demographics, nutritional status, obstetric morbidity and mortality, mental health problems, and sexually transmitted diseases, including HIV.
