Download or read book Advances in Psoriasis written by Jeffrey M. Weinberg and published by Springer. This book was released on 2014-08-28 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has become increasingly clear that psoriatic disease, both of the skin and joints, can be a significant diagnostic and therapeutic challenge for the physician and a debilitating illness for the patient. Genetic and immunologic advances have increased our understanding of the pathophysiology of psoriasis and psoriatic arthritis and there is a need for practically oriented evidence based references to describe the management options open to clinicians. The speed at which developments are occurring in the field also necessitates a novel approach to keeping up with these changes in practice and the need is for a reference that that be updated regularly as the subject requires. Psoriasis is an incredibly fast-moving discipline within dermatology. Guidelines, treatment options and management all change at incredible speed. There is a requirement to provide a comprehensive reference resource to provide practical, user friendly information for the dermatology profession to aid in the decision-making process. Psoriasis is a graphical subdiscipline of medicine and therefore this will have copious illustrations. As a fast moving discipline the emphasis must be on annual updates to ensure that readers are kept up to date on the important areas of development.

Download or read book Ophthalmic Disease Mechanisms And Drug Discovery written by Kang Zhang and published by World Scientific. This book was released on 2016-08-10 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: This invaluable book presents a concise discussion on the most important topics of ophthalmology — mechanism of ophthalmic diseases, imaging techniques used for diagnosis, novel therapies and drug delivery systems. It also covers current knowledge about anti-VEGF therapies that revolutionized neovascular AMD treatment, anti-inflammatory and dry eye treatment, as well as nanoparticles use of drug delivery.Written by experts in ophthalmology, this unique volume provides a comprehensive overview of the latest research in the field. This is an essential reading that will provide up-to-date reference to practicing physicians and current knowledge to residents and students.

Download or read book Genetic Engineering News written by and published by . This book was released on 2003 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Treatment and Care of the Geriatric Veterinary Patient written by Mary Gardner and published by John Wiley & Sons. This book was released on 2017-06-06 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment and Care of the Geriatric Veterinary Patient offers veterinarians a complete guide to treating and managing geriatric canine and feline patients. Offers practical guidance on managing all aspects of veterinary care in geriatric pets Takes a holistic approach to managing the geriatric patient, from common diseases and quality of life to hospice, euthanasia, client communications, and business management Focuses on dogs and cats, with a chapter covering common exotic animals Provides clinically oriented advice for ensuring quality of life for older pets Includes access to a companion website with videos, client education handouts, and images

Download or read book Adenosine Receptors in Health and Disease written by Constance N. Wilson and published by Springer Science & Business Media. This book was released on 2009-07-28 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since their discovery approximately 25 years ago, adenosine receptors have now emerged as important novel molecular targets in disease and drug discovery. These proteins play important roles in the entire spectrum of disease from inflammation to immune suppression. Because of their expression on a number of different cell types and in a number of different organ systems they play important roles in specific diseases, including asthma, rheumatoid arthritis, Parkinson’s disease, multiple sclerosis, Alzheimer’s disease, heart disease, stroke, cancer, sepsis, and obesity. As a result of intense investigations into understanding the molecular structures and pharmacology of these proteins, new molecules have been synthesized that have high specificity for these proteins and are now entering clinical trials. These molecules will define the next new classes of drugs for a number of diseases with unmet medical needs.

Download or read book Analytical Method Validation and Instrument Performance Verification written by Chung Chow Chan and published by John Wiley & Sons. This book was released on 2004-04-23 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Validation describes the procedures used to analyze pharmaceutical products so that the data generated will comply with the requirements of regulatory bodies of the US, Canada, Europe and Japan. Calibration of Instruments describes the process of fixing, checking or correcting the graduations of instruments so that they comply with those regulatory bodies. This book provides a thorough explanation of both the fundamental and practical aspects of biopharmaceutical and bioanalytical methods validation. It teaches the proper procedures for using the tools and analysis methods in a regulated lab setting. Readers will learn the appropriate procedures for calibration of laboratory instrumentation and validation of analytical methods of analysis. These procedures must be executed properly in all regulated laboratories, including pharmaceutical and biopharmaceutical laboratories, clinical testing laboratories (hospitals, medical offices) and in food and cosmetic testing laboratories.

Download or read book Clinical Toxicology Testing written by Barbarajean Magnani and published by . This book was released on 2020 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: "A comprehensive overview of clinical laboratory toxicology services and analytes"--

Download or read book An Atlas of Surgical Approaches to the Bones and Joints of the Dog and Cat written by Donald L. Piermattei and published by . This book was released on 2004 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This well-illustrated atlas provides detailed coverage of the surgical anatomy of the skeletal system of dogs and cats. The comprehensive coverage and vivid details allow surgeons to explore a variety of approaches to fit each unique clinical situation.

Download or read book Philosophy of Medicine written by Henrik R. Wulff and published by Wiley-Blackwell. This book was released on 1990 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Astrocytes and Epilepsy written by Jacqueline A. Hubbard and published by Academic Press. This book was released on 2016-07-05 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. - Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume - Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions - Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation

Download or read book Frontiers in Pharmacology of Neurotransmitters written by Puneet Kumar and published by Springer Nature. This book was released on 2020-10-29 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: Numerous phenomenal advances have been made towards understanding the role of neurotransmitters in the pathophysiology of neurological disorders, and these have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of such disorders. This book provides a comprehensive and detailed explanation of brain neurotransmitters and their receptors and associated channels. It includes a basic introduction, and also discusses the functions and recent advances and their pharmacology, highlighting the role of various computer aided drug design (CADD) strategies for the development of therapeutic ligands to modulate these receptors/ion channels. Written in an easy-to-read style, it is intended for neuroscience and pharmaceutical students and researchers working in the area of brain neurotransmitters.

Download or read book Skin Barrier Function written by T. Agner and published by Karger Medical and Scientific Publishers. This book was released on 2016-02-04 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.

Download or read book Forensic Investigation of Animal Cruelty written by Leslie Sinclair and published by . This book was released on 2006 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mild to Moderate Psoriasis Third Edition written by John Y. M. Koo and published by CRC Press. This book was released on 2014-03-18 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using a practical and problem-focused approach, this updated, full-color Third Edition of Mild-to-Moderate Psoriasis equips dermatologists, internists, family practitioners, and residents with a state-of-the-art guide to the clinical management of mild-to-moderate psoriasis.Written by an international team of key opinion leaders, this resource explores new developments in treatments for the condition and provides clinicians with up-to-date strategies for optimal patient management.

Download or read book Dr Petty s Pain Relief for Dogs The Complete Medical and Integrative Guide to Treating Pain written by Michael Petty and published by The Countryman Press. This book was released on 2016-02-01 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to diagnosing and relieving your dog's pain You love your dog, and hate to see him in pain. But you don’t want to head to the vet’s office for hundreds of dollars worth of tests that might prove useless. Dr. Mike Petty understands this. He’s a “pain vet” – working with cutting-edge research to find the best way to relieve your pet's pain. In this book, he guides readers in three critical points: 1. How to determine whether a dog is in pain 2. How to find a veterinarian capable of treating these pain issues. 3. What treatments are available, and which are worth pursuing and which are not. Dr. Petty offers clear descriptions of the treatments, both traditional and holistic. This guide offers the wisdom and support that dog owners crave in these situations.

Download or read book Therapeutic Targets written by Luis M. Botana and published by John Wiley & Sons. This book was released on 2012-04-20 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Latest Applications For Cellmechanism Research in Drug Discovery Designed to connect research on cell mechanisms with the drug discovery process, Therapeutic Targets: Modulation, Inhibition, and Activation introduces readers to a range of new concepts and novel approaches to drug screening and therapeutic drug targeting to help inform future avenues of drug research. Highly topical, this accessible edited volume features chapters contributed by respected experts from around the globe. The book helps postgraduate students and professional scientists working in academia and industry understand the molecular mechanisms of pharmacology, current pharmacological knowledge, and future perspectives in drug discovery, focusing on important biochemical protein targets and drug targeting strategies for specific diseases. Examining the pharmacology of therapeutically undefined targets and their potential applications, it includes chapters on traditional therapeutic targets, including enzymes (phosphodiesterases and proteases), ion channels, and G protein-coupled receptors, as well as more recently identified avenues of exploration, such as lipids, nuclear receptors, gene promoters, and more. Since different diseases require different targeting techniques, the book also includes dedicated chapters on strategies for investigating Alzheimer's, diabetes, pain, and inflammation treatments. Concluding with a cross-sectional look at new approaches in drug screening, Therapeutic Targets is an invaluable resource for understanding where the next generation of drugs are likely to emerge.

Download or read book Hair Loss and Replacement For Dummies written by William R. Rassman and published by John Wiley & Sons. This book was released on 2008-11-13 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are the causes of hair loss? Can you prevent it? Can lost hair be restored? Hair Loss & Replacement For Dummies helps you understand why men and women lose their hair and offers thorough, objective reviews of a wide array of hair replacement options, including hair replacement surgery, prescription and over-the-counter medicinal treatments, hairpieces, natural remedies, and a variety of other options. This authoritative, user-friendly guide explains the pros and cons of hairpieces, fibers, foundations, and hair thickening techniques. You’ll learn about pharmaceutical, laser, and topical treatments, and you’ll find out how to determine whether you’re good candidate for hair transplant surgery. You’ll even find help in assessing costs, controlling expectations, avoiding hair replacement scams, and determining which option truly is best for you. You’ll discover: What you need to know about hair and hair loss How to take better care of your hair Ways to prevent or reduce hair loss Creative techniques for concealing hair loss Shopping tips for hair-replacement systems How finesteride, minoxidil, and other medications might help Advice about low level laser treatments The low-down on hair transplant surgery Complete with helpful myth-busting information about the causes of hair loss and the benefits of FDA-approved treatments, and helpful comparisons of the advantages of non-surgical and surgical hair replacement, Hair Loss & Replacement For Dummies is the resource to consult before you decide on any hair replacement treatment.