Download or read book Coenzyme B12 Enzymes Part A written by and published by Academic Press. This book was released on 2022-05-17 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: B12 Enzyme, Volume 667 in the Methods in Enzymology serial, highlights new advances in the field with this new volume presenting timely, interesting chapters, including Part I: B12 Biosynthesis and B12 Chaperones, Probing the preference and regioselectivity of lower ligand activation and its role in cobamide diversity, Biosynthesis of corrinoids, The human B12 trafficking chaperones: CblC, CblD and ATR, A method for the efficient adenosylation of corrinoids, Production, purification and liposome reconstitution of cobamide synthase, Extraction and Purification of Cobamides from Bacterial Cultures, Part II: The many faces of B12-dependent enzyme reactions, Methylcobalamin-dependent methionine synthase, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology serials Includes the latest information on B12 Enzymes
Download or read book Coenzyme B12 Enzymes Part B written by and published by Academic Press. This book was released on 2022-05-27 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coenzyme B12 Enzymes, Part B, Volume 169 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on Structural characterization of cobalamin-dependent radical SAM methylases, Purification and characterization of sequential cobalamin-dependent radical SAM methylases ThnK and TokK in -lactam antibiotic biosynthesis, Characterization of the cobalamin-dependent radical S-adenosyl-L-methionine enzyme C-methyltransferase Fom3 in fosfomycin biosynthesis, Studies of OxsB and GenK, two B12-dependent radical SAM enzymes involved in natural product biosynthesis, Purification and structural elucidation of the cobalamin-dependent radical SAM enzyme OxsB, and more. Other chapters discuss Methods for studying the mechanisms of B12 enzymes, Computational investigations of B12 dependent enzymatic reactions, Using kinetic isotope effects to probe the mechanisms of adenosylcobalamin-dependent enzymes, Steady-state and pre-steady state kinetic analysis of ornithine 4,5-aminomutase, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology series Includes the latest information on B12 Enzymes
Download or read book Coenzyme B12 Enzymes written by E. Neil G. Marsh and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vitamin B 12 and B 12 Proteins written by Bernhard Kräutler and published by John Wiley & Sons. This book was released on 2008-07-11 with total page 559 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and topical book reviews the important developments in the 'B12-field' with regard to biological, chemical, pharmaceutical and medicinal aspects. In over 30 chapters the approx. 100 internationally renowned authors give deeper insight into the prospering research activites around B12. This book is a must for everybody who works with or on vitamins and porphyrine (-like) ring systems. Topics of particular interest include: Biosynthesis of Vitamin B12; B12-catalyzed enzymatic reactions and their mechanisms; structural B12-chemistry; reactivity of B12 and B12-models; structure and function of B12-proteins; metabolic transport and storage of B12; pathological effects of B12-deficiency.
Download or read book The Vitamin Co Factors of Enzyme Systems written by F. A. Robinson and published by Elsevier. This book was released on 2013-10-22 with total page 907 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Vitamin Co-Factors of Enzyme Systems provides a systematic account of the vitamin B complex, which play a fundamental role in a variety of biochemical reactions. This book reviews the vitamin B group in terms of their significance in enzymes reactions. Organized into 11 chapters, this book begins with an overview of the processes by which the main nutrients are broken down into simpler components. This text then explores the existence in foodstuffs of substances essential for the proper functioning of the animal organism. Other chapters consider the synthetic method of producing a commercially important chemical to be displaced by a method based on its isolation from natural sources. This book discusses as well the effect of various vitamin deficiencies in human beings. The final chapter deals with the series of changes that represents the biochemical reactions that occur during the contraction of muscles. This book is a valuable resource for biochemists and clinicians.
Download or read book Chemistry and Biochemistry of B12 written by Ruma Banerjee and published by John Wiley & Sons. This book was released on 1999-11-03 with total page 960 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Definitive New Reference for the Latest Advances in B_12 Chemistry and Biochemistry Over the past decade, the field of B_12 research has been revolutionized by such major breakthroughs as the unraveling of the entire biosynthetic pathway for this important vitamin. This comprehensive compendium surveys the wealth of information that has accumulated, covering in one volume virtually all aspects of the field-from physical and inorganic chemistry to enzymology, microbiology, medicine, and diagnostic and therapeutic applications. Edited by Dr. Ruma Banerjee, a highly respected and active member of the B_12 community, this work provides B_12 researchers with a dependable and up-to-date reference on the subject. Leading authorities from five continents explore such new areas as the structural biology of B_12-dependent enzymes, free-radical-mediated reaction mechanisms, biosynthesis, and much more. The role of B_12 in nutrition and disease, and B_12 transport, are also thoroughly examined. Complete with color illustrations and extensive references, Chemistry and Biochemistry of B_12 is a one-of-a-kind resource for biochemists, biophysicists, spectroscopists, microbiologists, molecular biologists, and anyone with an interest in "nature's most beautiful cofactor."
Download or read book Analysis of Enzymes of the Late Steps of Coenzyme B12 Biosynthesis in Archaea and Bacteria written by Michele M. Otte and published by . This book was released on 2009 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemistry of Plant Phosphorus Compounds written by Arlen Frank and published by Elsevier. This book was released on 2013-06-03 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides a high level reference source for scientists engaged in any aspect of plant research - chemistry, biochemistry or physiology - with primary focus on the chemistry of phosphorus-containing compounds that occur naturally in the plant kingdom, and specifically in the higher plants (Plantae). The book is comprehensive with respect to nomenclature, physical properties, and distribution worldwide. There are many tables of actual data on phosphorus compounds occurring in whole plants and parts of plants. The tables provide detailed data that is needed by the food industry, agriculture, etc as many of the phosphorus compounds are common to both plants and animals. Two appendices cover other aspects including changes in phosphorus-containing compounds during germination and their accumulation during growth and senescence. The final sections of the book comprise separate indexes of plants, compounds and authors. Comprehensive examination of phosphorus compounds found in plants Extensive tables listing types of compounds and their occurrence in plants including: Nomenclature; Occurrence; Physical Properties; Synthesis; Hydrolysis; Phosphorylation; Extraction; Separation and Analysis Easy to use indexes of plants, compounds and authors
Download or read book Organic Chemistry of Enzyme Catalyzed Reactions Revised Edition written by Richard B. Silverman and published by Elsevier. This book was released on 2002-03-07 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Organic Chemistry of Enzyme-Catalyzed Reactions is not a book on enzymes, but rather a book on the general mechanisms involved in chemical reactions involving enzymes. An enzyme is a protein molecule in a plant or animal that causes specific reactions without itself being permanently altered or destroyed. This is a revised edition of a very successful book, which appeals to both academic and industrial markets. Illustrates the organic mechanism associated with each enzyme-catalyzed reaction Makes the connection between organic reaction mechanisms and enzyme mechanisms Compiles the latest information about molecular mechanisms of enzyme reactions Accompanied by clearly drawn structures, schemes, and figures Includes an extensive bibliography on enzyme mechanisms covering the last 30 years Explains how enzymes can accelerate the rates of chemical reactions with high specificity Provides approaches to the design of inhibitors of enzyme-catalyzed reactions Categorizes the cofactors that are appropriate for catalyzing different classes of reactions Shows how chemical enzyme models are used for mechanistic studies Describes catalytic antibody design and mechanism Includes problem sets and solutions for each chapter Written in an informal and didactic style
Download or read book Studies on the Mechanism of Action of a Coenzyme B12 Dependent Enzyme Dioldehydrase written by Alex Yak Pung Cheung and published by . This book was released on 1983 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Purple Phototrophic Bacteria written by C.N. Hunter and published by Springer Science & Business Media. This book was released on 2008-10-11 with total page 1013 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is a comprehensive survey of all aspects of these fascinating bacteria, metabolically the most versatile organisms on Earth. It compiles 48 chapters written by leading experts, who highlight the huge progress made in studies of these bacteria since 1995.
Download or read book Mechanistic Investigations Into Coenzyme B12 Dependent Enzymes written by Daniel James Darley and published by . This book was released on 1999 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Laboratory Assessment of Vitamin Status written by Dominic J. Harrington and published by Academic Press. This book was released on 2018-11-28 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of ‘Best Practice’ approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status. Describes specialist assays in sufficient detail to enable laboratories to replicate what is being performed by expert groups Provides detailed information that supports laboratories in the setting up of methods for the evaluation of vitamin status Informs laboratories looking for third party providers of specialist investigations Provides an essential overview of reference ranges for each vitamin
Download or read book Mechanistic Investigation Into Coenzyme B12 Enzymes written by Daniele Ciceri and published by . This book was released on 2000 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Comprehensive B12 written by Zenon Schneider and published by Walter de Gruyter. This book was released on 2011-11-14 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Introduction to Enzyme and Coenzyme Chemistry written by T. D. H. Bugg and published by John Wiley & Sons. This book was released on 2012-05-29 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzymes are giant macromolecules which catalyse biochemical reactions. They are remarkable in many ways. Their three-dimensional structures are highly complex, yet they are formed by spontaneous folding of a linear polypeptide chain. Their catalytic properties are far more impressive than synthetic catalysts which operate under more extreme conditions. Each enzyme catalyses a single chemical reaction on a particular chemical substrate with very high enantioselectivity and enantiospecificity at rates which approach “catalytic perfection”. Living cells are capable of carrying out a huge repertoire of enzyme-catalysed chemical reactions, some of which have little or no precedent in organic chemistry. The popular textbook Introduction to Enzyme and Coenzyme Chemistry has been thoroughly updated to include information on the most recent advances in our understanding of enzyme action, with additional recent examples from the literature used to illustrate key points. A major new feature is the inclusion of two-colour figures, and the addition of over 40 new figures of the active sites of enzymes discussed in the text, in order to illustrate the interplay between enzyme structure and function. This new edition provides a concise but comprehensive account from the perspective of organic chemistry, what enzymes are, how they work, and how they catalyse many of the major classes of enzymatic reactions, and will continue to prove invaluable to both undergraduate and postgraduate students of organic, bio-organic and medicinal chemistry, chemical biology, biochemistry and biotechnology.
Download or read book Radical SAM Enzymes written by and published by Academic Press. This book was released on 2018-08-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radical SAM Enzymes, Volume 606, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Characterization of the glycyl radical enzyme choline trimethylamine-lyase and its radical S-adenosylmethionine activating enzyme, Diphathimide biosynthesis, Radical SAM glycyl radical activating enzymes, Radical SAM enzyme BioB in the biosynthesis of biotin, Biogenesis of the PQQ cofactor, Role of MoaAC in the biogenesis of the molybdenum cofactor, Biosynthesis of the nitrogenase cofactor, Bioinformatics of the radical SAM superfamily, The involvement of SAM radical enzymes in the biosynthesis of methanogenic coenzymes, methanopterin and coenzyme F420, and more.
