Download or read book Clinical Applications of Continuous Infusion Chemotherapy and Concomitant Radiation Therapy written by C. Julian Rosenthal and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first conference on concomitant infusion chemotherapy and radia tion therapy was organized with the intention of bringing together some of the investigators who have tested, during the last few years, the hypo thesis that continuous infusion chemotherapy could modulate the cytotoxic effect of radiation therapy to the point of having a strongly additive, if not synergistic activity on certain malignant tumors. This volume represents the detailed proceedings of this conference presented in a way that offers the reader a review of the on-going re search in the field. We have stressed a number of subjects from basic biologic research and influence of cell kinetics to the practical methods of drug delivery systems and early clinical experiences. The rationale for this new type of combined modality therapy has been presented by some of its pioneers. Early clinical investigations as well as the preliminary data of many that have not yet completely matured have also been included. The reader should look at these data with some reser vations. Ultimately, these results must be confirmed by larger prospective randomized studies with proper controls before becoming accepted as the treatment of choice in locally advanced tumors.
Download or read book Concomitant Continuous Infusion Chemotherapy and Radiation written by Marvin Rotman and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: The administration of chemotherapeutic agents by continuous infusion with concomitant radiation therapy heralds a new approach in the treatment of cancer. This comprehensive book on the subject includes, besides a discussion of its scientific basis, the most promising clinical data on the use of continuous infusion chemotherapy and radiation. Thus, it is an important update for clinical investigators involved in frontline research as well as for practicing physicians participating in the direct care of cancer patients. The contributions include the latest results of this new approach in a number of tumor sites. There is a detailed description of the principles of radiosensitization for malignant tumors and radioprotection for normal tissues; these are the principles which have led to concrete clinical applications. There is also a presentation of the most recent data on the beneficial effects resulting from the administration of commonly used drugs, such as 5-fluorouracil, cisplatinum and adriamycin, with concomitant radiation therapy. Much of the data has never before been published. The wealth of information in this volume makes it a valuable reference; at the same time it gives practicing physicians a detailed presentation of various therapeutic regimens which they could administer in their daily clinical practice. In the future, this innovative cancer treatment may lead to the decreased need for radical surgery and the increased ability to preserve organ function.
Download or read book Combined Modality Cancer Therapy written by Jacob J. Lokich and published by . This book was released on 1991 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: An innovative text presenting the experimental and clinical basis for combined modality cancer therapy. Special attention is given to employing infusional chemotherapy simultaneously with radiation.
Download or read book Cancer Chemotherapy by Infusion written by J.J. Lokich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemotherapy for-cancer is in a state of evolution. Because some cancers can now be cured with chemotherapy as a singular modality, this therapy can no longer be viewed as simply a palliative contribution. Chemotherapy has assumed an important role as an adjuvant to other modalities, including both surgery and radiation therapy. For some tumors, the primary application of chemotherapy in a combined modality approach to curative therapy has resulted in the application of less radical surgery while achieving substantial of relatively rare tumors such as cure rates. Nonetheless, with the exception childhood tumors, hematologic malignancies, and testicular cancer, the effec tiveness of chemotherapy in most tumors is severely limited. At the cellular level, greater understanding of the specific mechanism of tumor cell killing and of the phenomenon of drug resistance are elusive, critical ingredients in the improvement of effectiveness in cancer chemotherapy. Prolonging the exposure time of the tumor cell to drugs is a concept that was addressed in the early phases of the development of chemotherapy. How ever, technological limitations inhibited the broader application of chemother apy by infusion until recent years. Also, the convenience of intermittent ther apy on an outpatient basis, with the predominant theory of drug effect based on a dose response as well as the proven effectiveness of this schedule in some tumors, has slowed the process of subjecting infusion chemotherapy to the rigors of clinical trials.
Download or read book Stereotactic Body Radiation Therapy written by Simon S. Lo and published by Springer Science & Business Media. This book was released on 2012-08-28 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stereotactic body radiation therapy (SBRT) has emerged as an important innovative treatment for various primary and metastatic cancers. This book provides a comprehensive and up-to-date account of the physical/technological, biological, and clinical aspects of SBRT. It will serve as a detailed resource for this rapidly developing treatment modality. The organ sites covered include lung, liver, spine, pancreas, prostate, adrenal, head and neck, and female reproductive tract. Retrospective studies and prospective clinical trials on SBRT for various organ sites from around the world are examined, and toxicities and normal tissue constraints are discussed. This book features unique insights from world-renowned experts in SBRT from North America, Asia, and Europe. It will be necessary reading for radiation oncologists, radiation oncology residents and fellows, medical physicists, medical physics residents, medical oncologists, surgical oncologists, and cancer scientists.
Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Download or read book Rectal Cancer Treatment written by M.W. Büchler and published by Springer Science & Business Media. This book was released on 2005-10-11 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rectal cancer is one of the most prevalent cancers world-wide. It is also a paradigm for multimodal management, as the combination of surgery, chemotherapy and radiotherapy is often necessary to achieve the optimal outcome. Recently, international experts met in Heidelberg, Germany to discuss the latest developments in the management of rectal cancer, including the anatomic and pathologic basis, staging tools, surgical concepts including fast-track surgery and laparoscopic resection, functional outcome after surgery and the role of radio- and chemotherapy. This monograph summarizes this meeting and gives an extensive overview of the current concepts in management of rectal cancer.
Download or read book Temporal Bone Cancer written by Paul W. Gidley and published by Springer. This book was released on 2018-05-03 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume comprehensively reviews the current literature on temporal bone cancer and the multidisciplinary approaches used to managing these rare tumors. The text will review important medical issues as they specifically relate to temporal bone cancer such as advanced imaging, pathologic classification, skull base surgery, plastic reconstructive surgery, and advances in osseointegrated implants for hearing restoration. Additional chapters are dedicated to the evaluation and management, diagnostic radiology, surgical planning and techniques, radiotherapy, chemotherapy, and rehabilitation. An emphasis is placed on the multidisciplinary approach required for the optimal care of these rare tumors. Written by leaders in the field, Temporal Bone Cancer will be an invaluable resource for residents and fellows in Otolaryngology, Neurosurgery and Neurotology, and clinicians with interest in the primary tumors of the temporal bone.
Download or read book Radiology of Osteoporosis written by Stephan Grampp and published by Springer Science & Business Media. This book was released on 2008-03-18 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This second edition of "Radiology of Osteoporosis" has been fully updated so as to represent the current state-of-the-art. It provides a comprehensive overview of osteoporosis, the pathologic conditions that give rise to osteoporosis, and the complications that are frequently encountered. A collection of difficult cases involving pitfalls is presented, with guidance to their solution. The book will be invaluable to all with an interest in osteoporosis.
Download or read book Pediatric Uroradiology written by Richard Fotter and published by Springer Science & Business Media. This book was released on 2008-11-05 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fully updated and revised edition of a classic work takes full account of recent dramatic changes in the subject area. It describes in detail all aspects of pediatric uroradiology, embracing both recent developments and established concepts. New chapters have been added, for example on genetics in nephrourology and clinical management of important nephrourologic disorders. Short conclusions are included at the end of sections to provide the reader with key information.
Download or read book High Resolution Sonography of the Peripheral Nervous System written by Siegfried Peer and published by Springer Science & Business Media. This book was released on 2008-11-05 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first edition of this book, sonography of the peripheral nervous system has evolved further. This second, revised edition includes many state-of-the-art high-resolution images, the text has been adapted to reflect the current state of the literature, and information is presented using a more modern layout. This book provides a practical, clinically oriented overview of all aspects of sonographic diagnosis and interventional therapy of the peripheral nervous system.
Download or read book Intracranial Vascular Malformations and Aneurysms written by Michael Forsting and published by Springer Science & Business Media. This book was released on 2008-11-04 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the pathoanatomical, pathophysiological, and imaging features of vascular malformations and aneurysms of the brain and the modern, minimally invasive endovascular methods and techniques employed in their treatment. All chapters in the second revised edition of this book have been thoroughly updated. Readers will find this clearly organized book is richly illustrated with numerous informative CT, MR and DSA images, including high-end 7-Tesla MR images.
Download or read book Contrast Media written by Henrik S. Thomsen and published by Springer Science & Business Media. This book was released on 2009-03-23 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition of Contrast Media: Safety Issues and Guidelines, updates the successful first edition and contains new chapters. It provides an invaluable, unique and unparalleled source of information on the safety issues relating to contrast media.
Download or read book Coronary Radiology written by Matthijs Oudkerk and published by Springer Science & Business Media. This book was released on 2010-04-21 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of the first available monograph on coronary radiology. In line with recent advances, this edition places special emphasis on the role of non-invasive techniques, detailed information being provided on CT angiography with multidetector and dual-source tomography, 2D and 3D visualization techniques, and MR coronary angiography. Sections on invasive imaging techniques and coronary calcification are included. High-quality color images compliment the text.
Download or read book Inflammatory Diseases of the Brain written by Stefan Hähnel and published by Springer Science & Business Media. This book was released on 2009-01-24 with total page 235 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Download or read book Imaging of the Pancreas written by Emil J. Balthazar and published by Springer Science & Business Media. This book was released on 2010-04-10 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using numerous high-quality illustrations, this volume assesses strengths and limitations of techniques for the imaging of pancreatitis. Ultrasound, computed tomography, magnetic resonance imaging and interventional imaging are considered separately in the settings of acute and chronic pancreatitis, with an additional section on imaging of complications. The significance of the imaging findings for clinical and therapeutic decision making is clearly explained, and protocols are provided to help obtain the best possible images.
Download or read book Multimodal Concepts for Integration of Cytotoxic Drugs written by Martin J. Brown and published by Springer Science & Business Media. This book was released on 2006-08-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies. The second part comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented.
