Download or read book Normal pressure Tests of Circular Plates with Clamped Edges written by Albert E. McPherson and published by . This book was released on 1942 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fixture is described for making normal-pressure tests of flat plates 5 inches in diameter in which particular care was taken to obtain rigid clamping at the edges. Results are give for 19 plates, ranging in thickness from 0.015 to 0.072 inch. The center deflections and the extreme-fiber stresses at low pressures were found to agree with theoretical values; the center deflections at high pressures were 4 to 12 percent greater than the theoretical values. Empirical curves are derived of the pressure for the beginning of permanent set as a function of the dimensions of the plate and the tensile properties of the material.
Download or read book Vibration Analysis of Cylindrically Curved Panels with Simply Supported Or Clamped Edges and Comparison with Some Experiments written by John L. Sewall and published by . This book was released on 1967 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Voltage and Patch Clamping with Microelectrodes written by Thomas G Smith and published by Springer. This book was released on 2013-05-27 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited and authored by international experts on voltage and patch clamping, this volume is designed to help anyone undertaking experiments requiring the use of these techniques. The only book of its kind to bring together this wealth of information on theory as well as practical techniques, this is a volume that no one involved in voltage and patch clamping can afford to be without.
Download or read book Patch Clamp Methods and Protocols written by Peter Molnar and published by Springer Science & Business Media. This book was released on 2007 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described require a basic level of electrophysiological training and aid the researcher in pursuing new areas of electrophysiology and using the patch clamp technique effectively. Patch Clamp Methods and Protocols is divided into three sections that cover the major areas of patch clamp application: Pharmacology, Physiology, and Biophysics. The first section provides examples and step by step instructions on how to use whole-cell and single-channel patch clamp methods for testing drugs in industrial settings. The second section provides a wide selection of patch clamp applications in physiological studies. The last part focuses on the biophysical applications of the patch clamp method using single channel recordings or statistical analysis of whole-cell currents in order to obtain parameters that describe ion channel properties or transmitter release. Individual techniques are explored within the area that they are applied most often. Researchers will find Patch Clamp Methods and Protocols to be an invaluable aid in the design and execution of a wide variety of patch clamp experiments, both on their own and in conjunction with other state-of-the-art methodologies.
Download or read book Machinery written by Lester Gray French and published by . This book was released on 1915 with total page 954 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Patch Clamping written by Areles Molleman and published by John Wiley & Sons. This book was released on 2003-06-13 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells. Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results. This book will explain the basic principles and practical application of patch clamp electrophysiology Written in a non-technical style to ensure its broad appeal to novice users Takes a practical approach This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this technique, including an overview of membrane biophysics, standard experimental design, data analysis, and technical concerns
Download or read book Official Gazette of the United States Patent Office written by USA Patent Office and published by . This book was released on 1897 with total page 2308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Clamped written by David Blackwell and published by Lulu.com. This book was released on 2005-12-01 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Ben moved to the mountains he did so in the hope that he would find his true self. But he found himself surrounded by people doing their best to hide theirs. Clamped, set in the alpine ski resort of Courchevel, follows the path of a suburban chalet boy learning to snowboard who becomes embroiled in the world of a corrupt museum curator, two small-time scam artist public schoolboys and an ancient artefact with hallucinogenic powers.
Download or read book The role of delayed umbilical cord clamping to control infant anaemya in resource poor settings written by and published by Rozenberg Publishers. This book was released on 2007 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Dynamic Clamp written by Alain Destexhe and published by Springer Science & Business Media. This book was released on 2009-03-11 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dynamic-clamp is a fascinating electrophysiology technique that consists of merging living neurons with computational models. The dynamic-clamp (also called “conductance injection”) allows experimentalists and theoreticians to challenge neurons (or any other type of cell) with complex conductance stimuli generated by a computer. The technique can be implemented from neural simulation environments and a variety of custom-made or commercial systems. The real-time interaction between the computer and cell also enables the design of recording paradigms with unprecedented accuracy via a computational model of the electrode. Dynamic-Clamp: From Principles to Applications contains contributions from leading researchers in the field, who investigate these paradigms at the cellular or network level, in vivo and in vitro, and in different brain regions and cardiac cells. Topics discussed include the addition of artificially-generated synaptic activity to neurons; adding, amplifying or neutralizing voltage-dependent conductances; creating hybrid networks with real and artificial cells; attaching simulated dendritic tree structures to the living cell; and connecting different neurons. This book will be of interest to experimental biophysicists, neurophysiologists, and cardiac physiologists, as well as theoreticians, engineers, and computational neuroscientists. Graduate and undergraduate students will also find up-to-date coverage of physiological problems and how they are investigated.
Download or read book Patch Clamp Analysis written by Wolfgang Walz and published by Springer Science & Business Media. This book was released on 2008-02-06 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patch-Clamp Analysis: Advanced Techniques describes in reproducible detail all applications that involve patch pipet. Beginning with updated basic patch-clamp techniques, the book presents the newest developments, ranging from fast external solution switching and the switching of the pipet solution during recording, to the loose patch, the perforated patch, and the patch cram detection technique. The advanced techniques covered combine molecular biology and imaging to produce the patch pipet with RT-PCR and fluorometric techniques.
Download or read book Scientific Canadian Mechanics Magazine and Patent Office Record written by Canada. Patent Office and published by . This book was released on 1887 with total page 1550 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Associated Automotive Journal and Garage Dealer written by and published by . This book was released on 1909 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gigaseal Formation in Patch Clamping written by Majid Malboubi and published by Springer Science & Business Media. This book was released on 2013-07-24 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents an investigation of gigaseal formation using micro/nanotechnology. The aims of the book are twofold. First, it explains the mechanisms of gigaseal formation using the latest discoveries. Second, it provides practical techniques for frequent formation of high resistance seals. The formation of a high-resistance electrical seal, also known as a gigaseal, between a cell membrane and a glass micropipette tip is essential in patch-clamp experiments. Even though four decades have passed since the introduction of the patch-clamping technique by Neher and Sakmann, gigaseal formation remains an obstacle in developing the high-throughput ion channel screening systems required by the pharmaceutical industry. Here the authors share their latest methods for achieving gigaseal formation and describe techniques that are highly desirable at both research and industrial levels. Nanotechnology has been found to be a powerful tool for studying and modifying glass micropipettes and in tackling the problem of gigaseal formation.
Download or read book The Benefits of Delayed Cord Clamping written by and published by Xspurts.com. This book was released on with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Patch Clamp Technique written by Fatima Shad Kaneez and published by BoD – Books on Demand. This book was released on 2012-03-23 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a stimulating and interesting addition to the collected works on Patch clamp technique. Patch Clamping is an electrophysiological technique, which measures the electric current generated by a living cell, due to the movement of ions through the protein channels present in the cell membrane. The technique was developed by two German scientists, Erwin Neher and Bert Sakmann, who received the Nobel Prize in 1991 in Physiology for this innovative work. Patch clamp technique is used for measuring drug effect against a series of diseases and to find out the mechanism of diseases in animals and plants. It is also most useful in finding out the structure function activities of compounds and drugs, and most leading pharmaceutical companies used this technique for their drugs before bringing them for clinical trial. This book deals with the understanding of endogenous mechanisms of cells and their receptors as well as advantages of using this technique. It covers the basic principles and preparation types and also deals with the latest developments in the traditional patch clamp technique. Some chapters in this book take the technique to a next level of modulation and novel approach. This book will be of good value for students of physiology, neuroscience, cell biology and biophysics.
Download or read book CLAMP in Context written by Dani Cavallaro and published by McFarland. This book was released on 2012-01-09 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since its debut manga RG Veda, CLAMP has steadily asserted itself as one of the most widely renowned teams of manga artists, leaving a durable imprint in every established genre while also devising novel formulas along the way. Endowed not only with stylistic distinctiveness but also comprehensive cultural structure, CLAMP's output is distinguished by unique worldbuilding flair and visual vitality. Exploring a selection of CLAMP manga as well as anime it inspired, this volume examines CLAMP's broader philosophical underpinnings, its dedication to the invention of elaborate narrative constructs, its legendary passion for multilayered universes, and its symbolic interpretation of human identity. Throughout, the work highlights the team's incremental creation of a graphic constellation of unparalleled appeal.
