Download or read book Beyond Myalgic Encephalomyelitis Chronic Fatigue Syndrome written by Institute of Medicine and published by National Academies Press. This book was released on 2015-03-16 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are serious, debilitating conditions that affect millions of people in the United States and around the world. ME/CFS can cause significant impairment and disability. Despite substantial efforts by researchers to better understand ME/CFS, there is no known cause or effective treatment. Diagnosing the disease remains a challenge, and patients often struggle with their illness for years before an identification is made. Some health care providers have been skeptical about the serious physiological - rather than psychological - nature of the illness. Once diagnosed, patients often complain of receiving hostility from their health care provider as well as being subjected to treatment strategies that exacerbate their symptoms. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome proposes new diagnostic clinical criteria for ME/CFS and a new term for the illness - systemic exertion intolerance disease(SEID). According to this report, the term myalgic encephalomyelitis does not accurately describe this illness, and the term chronic fatigue syndrome can result in trivialization and stigmatization for patients afflicted with this illness. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome stresses that SEID is a medical - not a psychiatric or psychological - illness. This report lists the major symptoms of SEID and recommends a diagnostic process.One of the report's most important conclusions is that a thorough history, physical examination, and targeted work-up are necessary and often sufficient for diagnosis. The new criteria will allow a large percentage of undiagnosed patients to receive an accurate diagnosis and appropriate care. Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome will be a valuable resource to promote the prompt diagnosis of patients with this complex, multisystem, and often devastating disorder; enhance public understanding; and provide a firm foundation for future improvements in diagnosis and treatment.
Download or read book Chronic Fatigue Syndrome Genes and Infection written by Roberto Patarca-Montero and published by CRC Press. This book was released on 2003-09-25 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examine the role the Eta-1/Op gene may play in uncovering the cause of CFS! Current research indicates that chronic fatigue syndrome may have an infectious etiology and that genetic factors might determine a body's ability to overcome or fall victim to a chronic infection. Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm focuses on the Early T lymphocyte activation-1/osteopontin gene (Eta-1/Op), a cytokine that offers natural resistance to bacteria, and viruses that may play a role in the suspected link between microbial infections and CFS. Written by one of the leading experts in the field, the book details the historical, clinical, and scientific aspects of Eta-1/Op and its relationship to infectious agents such as Rickettsia. Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm centers on research triggered by the high percentage of CFS patients who associate the onset of the disorder with an apparently infectious illness. This unique book addresses the role of Eta-1/Op as part of a genetic program of cellular immunity that may help in the etiopathogenesis and treatment of CFS. It also presents information on the structure and regulation of the Eta-1/Op gene and protein, and the biological activities of Eta-1/Op in nonimmunological bodily systems and pathologies. Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm includes vital information on the Eta-1/Op gene's relationship to: flaviviruses and herpesviruses mycobacterial infections and HIV infection autoimmune disease cell-cell communication cellular motility the regulation of phosphate and calcium metabolism and much more! Chronic Fatigue Syndrome, Genes, and Infection: The Eta-1/Op Paradigm is an important addition to the continuing effort to unravel the pathogenesis of this crippling disorder. The book is an essential resource for healthcare professionals working with CFS patients and for the biomedical community as a whole.
Download or read book Pediatric Chronic Fatigue Syndrome written by Kenny De Meirleir and published by CRC Press. This book was released on 2007-02-07 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Help young CFS sufferers cope with this debilitating illness Chronic Fatigue Syndrome (CFS) is a debilitating illness that can have devastating effects for those afflicted, especially children and adolescents. Pediatric Chronic Fatigue Syndrome discusses this growing problem and its many facets in depth, including the mounting prevalence of incidents in the population and detailed explanations of diagnostic criteria. Case studies are provided to illustrate the issues those afflicted with CFS face, such as increasing isolation, decreasing school attendance, the length of time it typically takes to get diagnosed, and the impact on leisure activities. Current criteria for CFS were designed for use in adults, with few studies done on assessing how appropriate these criteria are for children and adolescents. Pediatric Chronic Fatigue Syndrome provides the criteria for first-time diagnosis of pediatric CFS and includes practical recommendations developed by the International Association of Chronic Fatigue Syndrome Pediatric Case Definition Working Group. This book closely examines the potential impact that Chronic Fatigue Syndrome has on child and adolescent functioning, psychological factors, social factors, and the suffering endured from symptoms. Guidelines are provided on ways ME-CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) can be addressed in primary practice. Topics in Pediatric Chronic Fatigue Syndrome include: ME/CFS CACFS (Chronic Fatigues Syndrome in Children and Adolescents) the common problem of Munchausen-by-proxy research on the psychosocial, family, and physical functioning comparing children and adolescents with CFS and those without CFS using theory in clinical practice guidelines on how ME/CFS can be addressed in primary practice overview of CFS aspects for healthcare professionals who may be called on to diagnose or treat the illness and more Pediatric Chronic Fatigue Syndrome is timely, important information for health professionals, researchers, counselors, caregivers, parents of children and adolescents with CFS, and patients with CFS.
Download or read book An International Perspective on the Future of Research in Chronic Fatigue Syndrome written by Christopher R. Snell and published by BoD – Books on Demand. This book was released on 2012-02-15 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: While the chapters in this book are a long way from solving the enigma that is CFS, they do represent important attempts to understand this complex and perplexing disease. A common theme in them all is CFS as a multisystem disease with the possibility of more than one cause and influenced by a variety of interacting factors. Further, they acknowledge the reality of CFS for persons with this disease and the importance of finding causes, treatments and ultimately a cure. As advanced biomedical research techniques are increasingly applied to the study of CFS, it is surely only a matter of time before biomarkers are identified, etiologies understood, and remedies devised.
Download or read book Biomedical Insights that Inform the Diagnosis of ME CFS written by Brett A. Lidbury and published by MDPI. This book was released on 2020-03-16 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a severe chronic health condition that is often misunderstood or ignored by health establishments. The lack of definitive diagnostic markers to separate ME/CFS patients from the healthy population as well as from other chronic disorders is problematic for both health professionals and researchers. A consortium of Australian researchers gathered to systematically understand ME/CFS, ranging from a deep analysis of clinical and pathology data to metabolomic profiles and the investigation of mitochondrial function. From this broad collaboration, a number of compelling insights have arisen that may form the basis of specific serum, blood, and/or urinary biomarkers of ME/CFS. This Special Edition reports on a conference centred on these biomedical discoveries, with other contributions, with a translation focus for predictive markers for ME/CFS diagnosis. By supporting health professionals with developments in diagnostics for this condition, the patients and their families will hopefully benefit from an improved recognition of the biomedical underpinnings of the condition and will be better able to access the care that is urgently required. This Special Edition contains a mix of speaker submissions and other accepted manuscripts that contributed to our objective of advancing biomedical insights to enable the accurate diagnosis of ME/CFS.
Download or read book The Human Herpesviruses written by Bernard Roizman and published by Raven Press (ID). This book was released on 1993 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt:
- Author : Roberto Patarca Montero
- Publisher : CRC Press
- Release : 2001-06-26
- ISBN : 9780789011282
- Pages : 266 pages
Enteroviral and Toxin Mediated Myalgic Encephalomyelitis Chronic Fatigue Syndrome and Other Organ Pa
Download or read book Enteroviral and Toxin Mediated Myalgic Encephalomyelitis Chronic Fatigue Syndrome and Other Organ Pa written by Roberto Patarca Montero and published by CRC Press. This book was released on 2001-06-26 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Share the results of 45 years of front-line medical research! This valuable book covers varied organ pathology in a wide range of syndromes induced by viral infection and toxin exposure. Enteroviral and Toxin Mediated Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Other Organ Pathologies discusses such lethal problems as cardiomyopathy, liver failure, pancreatic cancer, brain tumors, and renal disease, as well as the debilitating disorders of myalgic encephalomyelitis/chronic fatigue syndrome and other post-viral syndromes. This essential text is profusely illustrated with photographs, photomicrographs, charts, EKGs, X-rays, and graphic depictions of other medical test results. With case studies of individual patients and whole families, Enteroviral and Toxin Mediated Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Other Organ Pathologies brings you the benefit of seeing the patients and their illnesses in the context of their lifestyles, work histories, and family medical history. Not a retrospective survey using medical records alone, this unique book is the result of Dr. Richardson's more than 45 years doing research with the prestigious Newcastle Research Group while engaged in General Family Practice. The scope of this book includes: the complex relationship between host and virus the aftereffects of viral illnesses on various systems, including the cardiovascular, nervous, and endocrine discussions of varied effects of viral syndromes on different family members consideration of viral effects on mother and fetus during pregnancy ideas for treatment and further research Enteroviral and Toxin Mediated Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Other Organ Pathologies provides both powerful case studies and exciting theoretical considerations based on research. It is an essential tool for family physicians as well as researchers into post-viral syndromes and the effects of toxin exposure.
Download or read book Chronic Fatigue and Related Immune Deficiency Syndromes written by Paul J. Goodnick and published by American Psychiatric Publishing. This book was released on 1993 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest research in neurobiology and in biological psychiatry has led to the discovery of many interactions between mood states and alterations in brain neurochemistry, neuroendocrinology, and brain imaging. Chronic Fatigue and Related Immune Deficiency Syndromes presents a state-of-the-art synthesis of research into disorders of chronic fatigue. It examines the relationship of chronic fatigue and related immune deficiency syndromes to major biological depression and reviews how they are alike and how they differ in etiology, psychopathology, neuroendocrinology, neurochemistry, and treatment. The chapters on treatment review all the varying approaches currently being used (along with the theories on which they are based) to set the scene for future developments in antivirals and antidepressants. This comprehensive yet concise text presents what is known on chronic fatigue syndrome from the vantage point of experts in the fields of immunology, virology, and neuroendocrinology.
Download or read book Inherited Metabolic Disease in Adults written by Carla E. M. Hollak and published by Oxford University Press. This book was released on 2016 with total page 657 pages. Available in PDF, EPUB and Kindle. Book excerpt: As clinical management of inherited metabolic diseases (IMDs) has improved, more patients affected by these conditions are surviving into adulthood. This trend, coupled with the widespread recognition that IMDs can present differently and for the first time during adulthood, makes the need for a working knowledge of these diseases more important than ever. Inherited Metabolic Disease in Adults offers an authoritative clinical guide to the adult manifestations of these challenging and myriad conditions. These include both the classic pediatric-onset conditions and a number of new diseases that can manifest at any age. It is the first book to give a clear and concise overview of how this group of conditions affects adult patients, a that topic will become a growing imperative for physicians across primary and specialized care.
Download or read book Advances In ME CFS Research and Clinical Care written by Kenneth J. Friedman and published by Frontiers Media SA. This book was released on 2019-11-25 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2015, the Institute of Medicine (USA) issued a report critical of the research effort and clinical care for ME/CFS (Myalgic Encephalomyelitis/Chronic Fatigue Syndrome) formerly known as Chronic Fatigue Syndrome (CFS) and Chronic Fatigue Immune Deficiency Syndrome (CFIDS). While worldwide investigation into the cause and nature of ME/CFS remains disproportionately small, and treatment remains symptomatic and controversial, modest research continues in all aspects of this disease: epidemiology, possible infectious origins and other triggers, possible involvement of genetics, metabolism, and microbiome, influence of co-morbid conditions, and more. Treatment of patients consists of providing symptomatic relief. Guidance in doing so is provided for the clinician. School-age children require not only treatment but, as revealed in a 25-year retrospective study, continued engagement with peers and social activity. This e-book explores the breadth and depth of current ME/CFS research and clinical care. Its impact for other chronic, complex illnesses should not be overlooked.
Download or read book Translational Pain Research written by Lawrence Kruger and published by CRC Press. This book was released on 2009-11-24 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical
Download or read book Plague written by Kent Heckenlively and published by Simon and Schuster. This book was released on 2017-02-21 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: On July 22, 2009, a special meeting was held with twenty-four leading scientists at the National Institutes of Health to discuss early findings that a newly discovered retrovirus was linked to chronic fatigue syndrome (CFS), prostate cancer, lymphoma, and eventually neurodevelopmental disorders in children. When Dr. Judy Mikovits finished her presentation the room was silent for a moment, then one of the scientists said, “Oh my God!” The resulting investigation would be like no other in science. For Dr. Mikovits, a twenty-year veteran of the National Cancer Institute, this was the midpoint of a five-year journey that would start with the founding of the Whittemore-Peterson Institute for Neuro-Immune Disease at the University of Nevada, Reno, and end with her as a witness for the federal government against her former employer, Harvey Whittemore, for illegal campaign contributions to Senate Majority Leader Harry Reid. On this journey Dr. Mikovits would face the scientific prejudices against CFS, wander into the minefield that is autism, and through it all struggle to maintain her faith in God and the profession to which she had dedicated her life. This is a story for anybody interested in the peril and promise of science at the very highest levels in our country.
Download or read book Medically Unexplained Symptoms written by Robert W. Baloh and published by Springer Nature. This book was released on 2020-12-01 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the rapid advances in medical science, the majority of people who visit a doctor have medically unexplained symptoms (MUS), symptoms that remain a mystery despite extensive diagnostic studies. The most common MUS are back pain, abdominal pain, headache, fatigue, and dizziness. This book addresses the obstacles of managing people with MUS in our modern day society from both a historical and contemporary perspective. Most MUS are psychosomatic in origin, caused by a complex interaction between nature and nurture, between biological and psychosocial factors. Psychosomatic symptoms are as real and as severe as the symptoms associated with structural damage to the brain. Unique and concise, the book explores the biological and psychosocial mechanisms, the clinical features, and current and future treatments of common MUS. Exploring the unsolved in an accessible manner, Medically Unexplained Symptoms invokes the methodologies of medical science, history, and sociology to investigate how brain flaws can lead to debilitating symptoms.
Download or read book Mitochondrial Dysfunction written by Lawrence H. Lash and published by Elsevier. This book was released on 2013-10-22 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods in Toxicology, Volume 2: Mitochondrial Dysfunction provides a source of methods, techniques, and experimental approaches for studying the role of abnormal mitochondrial function in cell injury. The book discusses the methods for the preparation and basic functional assessment of mitochondria from liver, kidney, muscle, and brain; the methods for assessing mitochondrial dysfunction in vivo and in intact organs; and the structural aspects of mitochondrial dysfunction are addressed. The text also describes chemical detoxification and metabolism as well as specific metabolic reactions that are especially important targets or indicators of damage. The methods for measurement of alterations in fatty acid and phospholipid metabolism and for the analysis and manipulation of oxidative injury and antioxidant systems are also considered. The book further tackles additional methods on mitochondrial energetics and transport processes; approaches for assessing impaired function of mitochondria; and genetic and developmental aspects of mitochondrial disease and toxicology. The text also looks into mitochondrial DNA synthesis, covalent binding to mitochondrial DNA, DNA repair, and mitochondrial dysfunction in the context of developing individuals and cellular differentiation. Microbiologists, toxicologists, biochemists, and molecular pharmacologists will find the book invaluable.
Download or read book The Puzzle Solver written by Tracie White and published by Allen & Unwin. This book was released on 2021-01-19 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: At the age of twenty-seven, a mysterious illness began to eat away at Whitney Dafoe. It stole away the strength of his legs, then his voice, and his ability to eat, until even the sound of a footstep in his room became unbearable. For years, he underwent endless medical tests until finally receiving a diagnosis: Chronic Fatigue Syndrome. With no cure or successful treatment, Whitney's father, Ron Davis, PhD-a world class geneticist at Stanford University whose legendary research helped crack the code of DNA-suddenly changed the course of his career in a race against time to cure his son's debilitating condition. In The Puzzle Solver, journalist Tracie White-who wrote the viral and award-winning piece on Ron and his family in Stanford Medicine-tells the full story. In gripping prose, she masterfully takes readers along on this journey with Davis to solve one of the greatest mysteries in medicine.
Download or read book Somatization and Psychosomatic Symptoms written by Kyung Bong Koh and published by Springer Science & Business Media. This book was released on 2013-06-18 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, with contributions emanating from the 21st World Congress of Psychosomatic Medicine held in Seoul in August 2011, presents the latest evidence-based information about the mechanisms, assessment, and management of psychosomatic disorders from a biopsychosociocultural perspective. Somatization is a process characterized by excessive or inappropriate focus on physical symptoms that are medically unexplained. It is highly prevalent in primary care medicine, as somatoform (psychosomatic) disorders tend to be chronic and can cause significant personal suffering and social problems as well as financial burden.
Download or read book The Invisible Kingdom written by Meghan O'Rourke and published by Penguin. This book was released on 2023-02-28 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER FINALIST FOR THE 2022 NATIONAL BOOK AWARD FOR NONFICTION Named one of the BEST BOOKS OF 2022 by NPR, The New Yorker, Time, and Vogue “Remarkable.” –Andrew Solomon, The New York Times Book Review "At once a rigorous work of scholarship and a radical act of empathy.”—Esquire "A ray of light into those isolated cocoons of darkness that, at one time or another, may afflict us all.” —The Wall Street Journal "Essential."—The Boston Globe A landmark exploration of one of the most consequential and mysterious issues of our time: the rise of chronic illness and autoimmune diseases A silent epidemic of chronic illnesses afflicts tens of millions of Americans: these are diseases that are poorly understood, frequently marginalized, and can go undiagnosed and unrecognized altogether. Renowned writer Meghan O’Rourke delivers a revelatory investigation into this elusive category of “invisible” illness that encompasses autoimmune diseases, post-treatment Lyme disease syndrome, and now long COVID, synthesizing the personal and the universal to help all of us through this new frontier. Drawing on her own medical experiences as well as a decade of interviews with doctors, patients, researchers, and public health experts, O’Rourke traces the history of Western definitions of illness, and reveals how inherited ideas of cause, diagnosis, and treatment have led us to ignore a host of hard-to-understand medical conditions, ones that resist easy description or simple cures. And as America faces this health crisis of extraordinary proportions, the populations most likely to be neglected by our institutions include women, the working class, and people of color. Blending lyricism and erudition, candor and empathy, O’Rourke brings together her deep and disparate talents and roles as critic, journalist, poet, teacher, and patient, synthesizing the personal and universal into one monumental project arguing for a seismic shift in our approach to disease. The Invisible Kingdom offers hope for the sick, solace and insight for their loved ones, and a radical new understanding of our bodies and our health.