Download or read book Chromosome identification Medicine and Natural Sciences written by Torbjoern Caspersson and published by Elsevier. This book was released on 1973-01-01 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromosome Identification—Technique and Applications in Biology and Medicine contains the proceedings of the Twenty-Third Nobel Symposium held at the Royal Swedish Academy of Sciences in Stockholm, Sweden, on September 25-27,1972. The papers review advances in chromosome banding techniques and their applications in biology and medicine. Techniques for the study of pattern constancy and for rapid karyotype analysis are discussed, along with cytological procedures; karyotypes in different organisms; somatic cell hybridization; and chemical composition of chromosomes. This book is comprised of 51 chapters divided into nine sections and begins with a survey of the cytological procedures, including fluorescence banding techniques, constitutive heterochromatin (C-band) technique, and Giemsa banding technique. The following chapters explore computerized statistical analysis of banding pattern; the use of distribution functions to describe integrated profiles of human chromosomes; the uniqueness of the human karyotype; and the application of somatic cell hybridization to the study of gene linkage and complementation. The mechanisms for certain chromosome aberration are also analyzed, together with fluorescent banding agents and differential staining of human chromosomes after oxidation treatment. This monograph will be of interest to practitioners in the fields of biology and medicine.
Download or read book Chromosome Identification Technique and Applications in Biology and Medicine written by Torbjörn Caspersson and published by . This book was released on 1973 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosome Identification Technique and Applications in Biology and Medicine Proceedings of the Twenty Third Nobel Symposium Held September 25 27 1972 At the Royal Swedish Academy of Sciences Stockholm written by Nobel Symposium, 23D, Stockholm, 1972 and published by . This book was released on 1973 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosome Identification written by Torbjoern O. Caspersson and published by . This book was released on 1973 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosome Identification written by Nobel Symposium (23 : 1972 : Stockholm) and published by Academic Press. This book was released on 1973-01-01 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosome Identification technique and Application in Biology and Medicine written by Torbjörn Oskar Caspersson and published by . This book was released on 1973 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mapping and Sequencing the Human Genome written by National Research Council and published by National Academies Press. This book was released on 1988-01-01 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evolution of Translational Omics written by Institute of Medicine and published by National Academies Press. This book was released on 2012-09-13 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.
Download or read book Clinical Precision Medicine written by Judy S. Crabtree and published by Academic Press. This book was released on 2019-11-15 with total page 114 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine. Includes applied discussions of chromosomes and chromosomal abnormalities, molecular genetics, epigenetic regulation, heredity, clinical genetics, pharmacogenomics and immunogenomics Features chapter contributions from leaders in the field Consolidates fundamental concepts and current practices of precision medicine in one convenient resource
Download or read book Exploring the Biological Contributions to Human Health written by Institute of Medicine and published by National Academies Press. This book was released on 2001-07-02 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.
Download or read book Atlas of Human Chromosome Heteromorphisms written by H.E. Wyandt and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: Critical to the accurate diagnosis of human illness is the need to distinguish clinical features that fall within the normal range from those that do not. That distinction is often challenging and not infrequently requires considerable experience at the bedside. It is not surprising that accurate cytogenetic diagnosis is also often a challenge, especially when chromosome study reveals morphologic findings that raise the question of normality. Given the realization that modern human cytogenetics is just over five decades old, it is noteworthy that thorough documentation of normal chromosome var- tion has not yet been accomplished. One key diagnostic consequence of the inability to distinguish a “normal” variation in chromosome structure from a pathologic change is a missed or inaccurate diagnosis. Clinical cytogeneticists have not, however, been idle. Rather, progressive biotechnological advances coupled with virtual completion of the human genome project have yielded increasingly better microscopic resolution of chromosome structure. Witness the progress from the early short condensed chromosomes to the later visualization of chromosomes through banding techniques, hi- resolution analysis in prophase, and more recently to analysis by fluorescent in situ hybridization (FISH).
Download or read book Screening for Down s Syndrome written by J. G. Grudzinskas and published by Cambridge University Press. This book was released on 1994-11-17 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important new publication summarises the recent exciting advances in screening for Down's syndrome. It addresses important clinical questions such as: risk assessment, who to screen, when to screen, which techniques to use, and the organisation of screening programmes nationally and internationally. An international and authoritative team of authors has been invited to assess the latest developments in this rapidly advancing area. The volume provides a critical and much needed evaluation of the potential and limitations of new and established techniques for screening for Down's syndrome. It will serve as an essential source of information for all those involved in pre-natal diagnosis and the provision of obstetric care.
Download or read book Chemistry in Botanical Classification Medicine and Natural Sciences written by Gerd Bendz and published by Elsevier. This book was released on 2013-10-14 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicine and Natural Sciences: Chemistry in Botanical Classification contains the proceedings of the Twenty-Fifth Nobel Symposium held in Sodergarn, Sweden, on August 20-25, 1973. The papers explore the chemical approach to plant classification and cover topics ranging from chemosystematics and applications of special classes of compounds to insects and plant chemotaxonomy. Biosynthetic pathways in chemical phylogeny and some aspects of organic geochemistry are also discussed. This book is comprised of 32 chapters divided into five sections. The first chapter provides an overview of the chemical approach to botanical classification, with special reference to the higher taxa of Magnoliophyta. The reader is then introduced to chemosystematics and the construction of phylogenetic schemes, as well as the use of a chemical character for the classification of living organisms. The following chapters focus on The chemistry of disjunct taxa; homology of biosynthetic routes; and applications of special classes of compounds such as flavonoids. The systematic distribution of ellagitannins in relation to the phylogeny and classification of the angiosperms is also considered. The final chapter describes phytochemical and biological procedures for screening of plant materials. This monograph will be of value to botanists, plant taxonomists, and chemists.
Download or read book Evolutionary Biology written by Max Hecht and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ninth volume of Evolutionary Biology represents a turning point in the history of this series. The death of Theodosius Dobzhansky was a blow to the whole field of evolutionary biology in general, and to his friends and colleagues, including the other two Editors. He played a central role in the selection of areas that were "ripe" for review papers, and his circle of friends, colleagues, and students was so wide that he could always find exactly the most appropriate author and then convince him that he should prepare the paper. Evolutionary Biology was founded in 1966 and the first volume published in 1967. Ten years-and several vicissitudes-later, it seems advisable to restate the original concept of this serial publication. The Preface of Volume 1 says, simply, We have conceived this serial as a forum in which critical reviews and com mentaries, as well as original papers and even controversial views, can be brought together to cover a broad range of interest with provocative discussion. Evolutionary Biology will provide research workers and students with an excep tional opportunity to read expert presentations of developments in areas of their field in which they are not specialists, and as specialists they will see how others assess these developments. An important feature is that contributions are not necessarily limited in length, subject, and other restrictions that usually prevail in basic research journals.
Download or read book Flow Cytogenetics written by and published by Academic Press. This book was released on 2012-12-02 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to be devoted entirely to the application and development of flow techniques in cytogenetics. It provides comprehensive information on the use of flow cytometry and sorting for chromosome classification and purification. Cytogenetics and molecular biologists will find this book an invaluable reference source. Practical details for the preparation and analysis of chromosomes using flow cytometry Flow karyotyping for sensitive rapid analysis of chromosome normality and the detection of aberrant chromosomes Flow sorting as a source of chromosome-specific DNA for gene mapping and recombinant DNA libraries Construction and current status of chromosome-specific recombinant DNA libraries
Download or read book Human Chromosome Atlas written by Claudia Behrend and published by Springer. This book was released on 2017-07-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: This atlas presents the results of cases of structural chromosome aberrations based on the currently available methods of analysis for different types of abnormality. It particularly focuses on which spectrum should be chosen when combining the different techniques to achieve the best method of diagnosis in individual cases, for example direct preparation of cells and mitoses, short or long-time cell culture, fluorescence in situ hybridization (FISH), analysis of interphases, microarray or DNA sequencing. Generally it has to be taken into account, that the development of new and improved investigation methods is forthcoming. Thus, by improvement of diagnostic possibilities new fields of investigation arise, and special groups of patients with cytogenetic analyses can be re-analysed under new research questions.
