Download or read book Chromosomal Proteins And Their Role In The Regulation Of Gene Expression written by Gary Stein and published by Elsevier. This book was released on 2012-12-02 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chromosomal Proteins and Their Role in the Regulation of Gene Expression examines how chromosomal proteins take part in the regulation of gene expression. This book also looks at the variety of approaches that are used in studying the structural and functional properties of chromosomal proteins, particularly as they relate to the control of transcription. This text is organized into 15 chapters and begins by analyzing the regulation of histone gene expression during the cell cycle and the role of non-histone chromosomal proteins in such regulation. The following chapters focus on the in vitro transcription of the globin gene in mouse fetal liver chromatin; the involvement of non-histone proteins in both positive and negative controls of gene activity; and the role of phosphorylated proteins as regulators of gene activity. The discussion then shifts to the phosphorylation state of non-histone proteins and its correlation with gene transcription; changes in nuclear proteins during embryonic development and cellular differentiation; and the manner by which histones are deposited onto replicating chromosomes. This book also explains the histone methylation, specific phosphorylation sites in lysine rich (H1) histone, and the separation and characterization of nuclear non-histone proteins by means of DNA columns. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in genetics, cell biology, molecular biology, biochemistry, and microbiology.
Download or read book Chromosomal Proteins and Their Role in the Regulation of Gene Expression written by Lewis Joel Kleinsmisth and published by . This book was released on 1975 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosomal Proteins and Their Role in the Regulation of Gene Expression written by and published by . This book was released on 1975 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosomal Proteins and Gene Expression written by Gerald R. Reeck and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book stems from an Advanced Study Institute on Chromo somal Proteins and Gene Expression that was held in Sitges, Spain, on September 17-26, 1984. It would be misleading to call this volume a conference proceedings, however. The ASI was not a conference, but a course with diverse activities, only one of which was a set of major presentations by the lecturers. Indeed, the concept of lecturer was intentionally obscured as we all learned from each other through shorter presentations by other participants and through seminars, poster sessions, and small group discussions. Furthermore, many participants found that exchanging ideas outside organized sessions was among the most rewarding aspects of the course. Some even claimed to have profitably probed the intricacies of nucleosome structure and transcriptional regulation while basking in the sun on the beachl Obviously, it is difficult to catch the flavor of such varied proceedings in a book. (I cannot confirm the incident on the beach, never having found time to set foot there. Such is the fate of the director of a meeting. ) The ASI was judged a success -- and enthusiastically so - by most participants. Not only did we deepen our understanding of our scientific field, we made new friends and learned about scientific and nonscientific aspects of life in other countries and about issues that transcend international boundaries in our complex world. We hope that this volume will be as successful as the course was.
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosomal Proteins and Their Role in the Regulation of Gene Expression written by and published by . This book was released on 1975 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chromosomal Proteins and Their Role in the Regulation of Gene Expression written by Florida Colloquium on molecular biology (1975: Florida) and published by . This book was released on 1975 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Administration and coordination of genetic expression by proteins structuring the genome written by Michèle Amouyal and published by Frontiers E-books. This book was released on 2013-06-03 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: These last years, a new class of proteins involved in the regulation of gene expression has been unraveled besides such classical elements as polymerases, transcription factors or enhancers, directly responsible for gene expression. This class introduces a second order level of regulation which is superimposed on that of the standard regulators and is revealed by epigenetic modifications. One end of this group is occupied by the so-called gene insulators such as CTCF that organize the action of the standard regulators and of invasive chromatin in order to limit and target their action to a specific gene or genetic entity. At the other end, one would find the proteins operating at the level of the whole genome and of cellular programming, such as SATB1. They are specific proteins nearly totally dedicated to organization and coordination of gene expression, like CTCF, or proteins also found involved in other cellular devices, like transcription factors extracted from the transcriptional machinery , such as TFIIIC, or proteins involved in sister chromatid cohesion, like cohesin. But they share in common to generally act over long distances or between chromosomes, to structure a true intra- or inter-chromosomal genomic architecture, and to mainly act at the epigenetic level. Their role in the control of gene expression is certified by the increasing number of pathologies to which their dysfunction contributes.
Download or read book Epigenetic Mechanisms of Gene Regulation written by Vincenzo E. A. Russo and published by . This book was released on 1996 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.
Download or read book Gene Regulation written by David S. Latchman and published by Nelson Thornes. This book was released on 1998 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The previous editions of Gene Regulation have helped students in biological science and medicine gain a full understanding of the issues of gene regulation. In this edition, new material reflects the progress that has been made in the understanding of gene regulation. The most significant change is the addition of an extra chapter describing the basic processes by which DNA is converted in RNA and then into protein. This important new chapter makes this edition complete as a textbook on gene expression and its regulation.
Download or read book Long Range Control of Gene Expression written by Veronica van Heyningen and published by Academic Press. This book was released on 2011-09-02 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: Long-Range Control of Gene Expression covers the current progress in understanding the mechanisms for genomic control of gene expression, which has grown considerably in the last few years as insight into genome organization and chromatin regulation has advanced. Discusses the evolution of cis-regulatory sequences in drosophila Includes information on genomic imprinting and imprinting defects in humans Includes a chapter on epigenetic gene regulation in cancer
Download or read book Eukaryotic Gene Regulation written by Gerald M. Kolodny and published by CRC Press. This book was released on 2018-01-18 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The cause of cancer and its many manifestations is at present unknown. Since many of its manifestations, including is control of cell division, appear to represent abnormal patterns of gene expression, studies of the regulation of gene expression nwill provide important insights in the understanding and treatment of cancer. This volume attempts to present some of the recent work on regulation of gene expression in eukaryotic cells.
Download or read book Chromatin written by Alan P. Wolffe and published by Academic Press. This book was released on 2012-12-02 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Third Edition of Chromatin: Structure and Function brings the reader up-to-date with the remarkable progress in chromatin research over the past three years. It has been extensively rewritten to cover new material on chromatin remodeling, histone modification, nuclear compartmentalization, DNA methylation, and transcriptional co-activators and co-repressors. The book is written in a clear and concise fashion, with 60 new illustrations. Chromatin: Structure and Function provides the reader with a concise and coherent account of the nature, structure, and assembly of chromatin and its active involvement in the processes of DNA transcription, replication and repair. This book consistently interrelates the structure of eukaryotic DNA with the nuclear processes it undergoes, and will be essential reading for students and molecular biologists who want to really understand how DNA works. Written in a clear and concise fashion Includes 60 new illustrations Extensively rewritten Brings the reader up-to-date with the remarkable progress in chromatin research over the past three years.
Download or read book Gene Regulation written by Bert O'Malley and published by Elsevier. This book was released on 2012-12-02 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Regulation documents the proceedings of the CETUS-UCLA Symposium ""Gene Regulation,"" held in Keystone, Colorado in March/April 1982. The symposium related gene structure and regulatory sequences to overall genomic organization and genetic evolution. It was the first meeting to focus on regulation of eukaryotic gene expression since the maturation in recombinant DNA technology. The book is organized into four parts. Part I presents studies on the structure of eukaryotic genes, including the organization and molecular basis for differential expression of the mouse ? light chain genes; globin gene transcription and RNA processing; and the cloning of the human chromosomal a1-antitrypsin gene and its structural comparison with the chicken gene coding for ovalbumin. Part II on chromatin structure includes papers on nuclease sensitivity of the ovalbumin gene and its flanking DNA sequences; and the relationship of chromatin structure to DNA sequence. Part III on gene expression includes papers on the role of poly(A) in eukaryotic mRNA metabolism and the in vitro transcription of Drosophila tRNA genes. Part IV on cellular biology includes studies such as the importance of calmodulin to the eukaryotic cells.
Download or read book The Role of Chromosomes in Development written by Michael Locke and published by Elsevier. This book was released on 2012-12-02 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Role of Chromosomes in Development is a collection of papers presented at the 23rd Symposium of the Society for the Study of Development and Growth, held at Amherst, Massachusetts in June 1964. Contributors explore the role of chromosomes in development, highlighting important processes such as the diversification and specialization of cells; the regulation of gene function by the physical state of the chromosome; the functional organization of chromosomes; DNA replication and synthesis; and macronuclear differentiation and subnuclear assortment. This volume is organized into 11 chapters and begins with an overview of chromosome structure and function and the mechanisms underlying the role of the chromosome in embryonic development. This book then discusses the chromosomal DNA replication, the mechanisms of gene modulation, the binding of actinomycin to DNA, and the cytological aspects of DNA replication in higher animals. The next chapters explain localized DNA synthesis in polytene chromosomes; chromosomal RNA and other nuclear RNA fractions; and experimental work probing both genetic and functional mosaicism in the mouse, as well as genetic repression of the R locus in maize. The book also considers how developmental pathways are controlled by genetic mechanisms, and then concludes with a chapter on nuclear differentiation in ciliates and on the phenomenon of subnuclear assortment. This book will be of interest to developmental biologists and embryologists.
Download or read book Fundamentals of Chromatin written by Jerry L. Workman and published by Springer Science & Business Media. This book was released on 2013-12-04 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.
Download or read book Histones and Other Basic Nuclear Proteins written by Gary S. Stein and published by CRC Press. This book was released on 1989-06-30 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive book is a compilation of Professor Lubomir S. Hnilica's twenty years of research experimentally addressing the chemistry and the biological functions of chromosomal proteins. The histones and other nuclear proteins found associated with DNA in a number of tissues and cell types are featured. Lubomir Hnilica played a major role in establishing the extent to which these basic chromosomal polypeptides are conserved and the manner in which they interact with DNA to modify chromatin structure. In addition, non-histone chromosomal protein research is explained, and his technique of applying several biochemical and immunological approaches to the characterization of this complex and heterogeneous class of chromosomal polypeptides is discussed. Highlighted is the use of chemical crosslinking for studying protein/DNA interactions in intact cells. The proteins as well as the structure, organization, and regulation of the genes are also presented.
