Download or read book Biocalorimetry written by Margarida Bastos and published by CRC Press. This book was released on 2016-06-22 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Connecting past, present, and future instrument development and use, Biocalorimetry: Foundations and Contemporary Approaches explores biocalorimetry's history, fundamentals, methodologies, and applications. Some of the most prominent calorimeter developers and users share invaluable personal accounts of discovery, discussing innovative techniques a

Download or read book Analytical Methodologies for Biofilm Research written by Moupriya Nag and published by Springer. This book was released on 2021-07-10 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book provides the readers of various discipline an easy understanding of the latest biophysical techniques pertaining to microbiology. Biofilm associated chronic infection is a major health problem and a serious concern to doctors, scientists and other health workers as it develops antibiotic and multi-drug resistance. This book describes various protocols utilized in the detection of the biofilm. The book has been divided into six sub sections which provides pertinent information about the various biophysical techniques and instruments that are used for detecting and analyzing the biofilm formation upon biotic and abiotic surfaces. The readers will be able to identify the techniques that can best cater information to solve the problem at hand. This book attempts to compile the latest information on the recent advances in the various functional aspects of microbial biofilms, their pathogenesis, present day treatments as well as detection strategies. This book is meant for researchers in the field of microbiology and interested in understanding microbial pathogenesis, quorum sensing and biofilm formation.

Download or read book Advances in Microbiology Infectious Diseases and Public Health written by Gianfranco Donelli and published by Springer Nature. This book was released on 2019-12-11 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original research and review articles present and discuss multidisciplinary findings and developments on various aspects of microbiology, infectious diseases, and their diagnosis, treatment and prevention. The book series publishes review and original research contributions, short reports as well as guest edited thematic book volumes. All contributions will be published online first and collected in book volumes. There are no publication costs. Advances in Microbiology, Infectious Diseases and Public Health is a subseries of Advances in Experimental Medicine and Biology, which has been publishing significant contributions in the field for over 30 years and is indexed in Medline, Scopus, EMBASE, BIOSIS, Biological Abstracts, CSA, Biological Sciences and Living Resources (ASFA-1), and Biological Sciences. 2018 Impact Factor: 2.126.

Download or read book The Perfect Slime written by Hans-Curt Flemming and published by IWA Publishing. This book was released on 2016-09-15 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Perfect Slime presents the latest state of knowledge and all aspects of the Extracellular Polymeric Substances, (EPS) matrix – from the ecological and health to the antifouling perspectives. The book brings together all the current material in order to expand our understanding of the functions, properties and characteristics of the matrix as well as the possibilities to strengthen or weaken it. The EPS matrix represents the immediate environment in which biofilm organisms live. From their point of view, this matrix has paramount advantages. It allows them to stay together for extended periods and form synergistic microconsortia, it retains extracellular enzymes and turns the matrix into an external digestion system and it is a universal recycling yard, it protects them against desiccation, it allows for intense communication and represents a huge genetic archive. They can remodel their matrix, break free and eventually, they can use it as a nutrient source. The EPS matrix can be considered as one of the emergent properties of biofilms and are a major reason for the success of this form of life. Nevertheless, they have been termed the “black matter of biofilms” for good reasons. First of all: the isolation methods define the results. In most cases, only water soluble EPS components are investigated; insoluble ones such as cellulose or amyloids are much less included. In particular in environmental biofilms with many species, it is difficult to impossible isolate, separate the various EPS molecules they are encased in and to define which species produced which EPS. The regulation and the factors which trigger or inhibit EPS production are still very poorly understood. Furthermore: bacteria are not the only microorganisms to produce EPS. Archaea, Fungi and algae can also form EPS. This book investigates the questions, What is their composition, function, dynamics and regulation? What do they all have in common?

Download or read book Theory and Applications of Heat Transfer in Humans 2 Volume Set written by Devashish Shrivastava and published by John Wiley & Sons. This book was released on 2018-04-16 with total page 890 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative guide to theory and applications of heat transfer in humans Theory and Applications of Heat Transfer in Humans 2V Set offers a reference to the field of heating and cooling of tissue, and associated damage. The author—a noted expert in the field—presents, in this book, the fundamental physics and physiology related to the field, along with some of the recent applications, all in one place, in such a way as to enable and enrich both beginner and advanced readers. The book provides a basic framework that can be used to obtain ‘decent’ estimates of tissue temperatures for various applications involving tissue heating and/or cooling, and also presents ways to further develop more complex methods, if needed, to obtain more accurate results. The book is arranged in three sections: The first section, named ‘Physics’, presents fundamental mathematical frameworks that can be used as is or combined together forming more complex tools to determine tissue temperatures; the second section, named ‘Physiology’, presents ideas and data that provide the basis for the physiological assumptions needed to develop successful mathematical tools; and finally, the third section, named ‘Applications’, presents examples of how the marriage of the first two sections are used to solve problems of today and tomorrow. This important text is the vital resource that: Offers a reference book in the field of heating and cooling of tissue, and associated damage. Provides a comprehensive theoretical and experimental basis with biomedical applications Shows how to develop and implement both, simple and complex mathematical models to predict tissue temperatures Includes simple examples and results so readers can use those results directly or adapt them for their applications Designed for students, engineers, and other professionals, a comprehensive text to the field of heating and cooling of tissue that includes proven theories with applications. The author reveals how to develop simple and complex mathematical models, to predict tissue heating and/or cooling, and associated damage.

Download or read book Surface Science Techniques written by Gianangelo Bracco and published by Springer Science & Business Media. This book was released on 2013-01-11 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book describes the experimental techniques employed to study surfaces and interfaces. The emphasis is on the experimental method. Therefore all chapters start with an introduction of the scientific problem, the theory necessary to understand how the technique works and how to understand the results. Descriptions of real experimental setups, experimental results at different systems are given to show both the strength and the limits of the technique. In a final part the new developments and possible extensions of the techniques are presented. The included techniques provide microscopic as well as macroscopic information. They cover most of the techniques used in surface science.

Download or read book Environmental Protection Strategies for Sustainable Development written by Abdul Malik and published by Springer Science & Business Media. This book was released on 2011-09-18 with total page 613 pages. Available in PDF, EPUB and Kindle. Book excerpt: The environment of our planet is degrading at an alarming rate because of non-sustainable urbanization, industrialization and agriculture. Unsustainable trends in relation to climate change and energy use, threats to public health, poverty and social exclusion, demographic pressure and ageing, management of natural resources, biodiversity loss, land use and transport still persist and new challenges are arising. Since these negative trends bring about a sense of urgency, short term action is required, whilst maintaining a longer term perspective. The main challenge is to gradually change our current unsustainable consumption and production patterns and the nonintegrated approach to policy-making. This book covers the broad area including potential of rhizospheric microorganisms in the sustainable plant development in anthropogenic polluted soils, bioremediation of pesticides from soil and waste water, toxic metals from soil, biological treatment of pulp and paper industry wastewater, sustainable solutions for agro processing waste management, solid waste management on climate change and human health, environmental impact of dyes and its remediation. Various methods for genotoxicity testing of environmental pollutants are also discussed and chapters on molecular detection of resistance and transfer genes in the environmental samples, biofilm formation by the environmental bacteria, biochemical attributes to assess soil ecosystem sustainability, application of rhizobacteria in biotechnology, role of peroxidases as a tool for the decolorization and removal of dyes and potential of biopesticides in sustainable agriculture. It offers a unique treatment of the subject, linking various protection strategies for sustainable development, describing the inter-relationships between the laboratory and field eco-toxicologist, the biotechnology consultant, environmental engineers and different international environmental regulatory and protection agencies.

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Download or read book Fast Scanning Calorimetry written by Christoph Schick and published by Springer. This book was released on 2016-06-28 with total page 796 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past decades, the scan rate range of calorimeters has been extended tremendously at the high end, from approximately 10 up to 10 000 000 °C/s and more. The combination of various calorimeters and the newly-developed Fast Scanning Calorimeters (FSC) now span 11 orders of magnitude, by which many processes can be mimicked according to the time scale(s) of chemical and physical transitions occurring during cooling, heating and isothermal stays in case heat is exchanged. This not only opens new areas of research on polymers, metals, pharmaceuticals and all kinds of substances with respect to glass transition, crystallization and melting phenomena, it also enables in-depth study of metastability and reorganization of samples on an 1 to 1000 ng scale. In addition, FSC will become a crucial tool for understanding and optimization of processing methods at high speeds like injection molding. The book resembles the state-of-the art in Thermal Analysis & Calorimetry and is an excellent starting point for both experts and newcomers in the field.

Download or read book Biothermodynamics written by Urs von Stockar and published by CRC Press. This book was released on 2013-05-30 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the fundamentals of the rapidly growing field of biothermodynamics, showing how thermodynamics can best be applied to applications and processes in biochemical engineering. It describes the rigorous application of thermodynamics in biochemical engineering to rationalize bioprocess development and obviate a substantial fraction of t

Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

Download or read book Novel Antibacterial Agents written by Fiorella Meneghetti and published by Mdpi AG. This book was released on 2022-01-12 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book was devoted to the latest advances achieved in the antibacterial field, with a focus on the recent efforts made to develop new antimicrobial agents with novel modes of action, and a perspective on future directions of this line of research. Antimicrobial resistance has become a major threat to global health, and the twenty-two published articles here reported put in evidence that the discovery and development of new antibiotics are extremely challenging. The antimicrobial research covers a wide area, spanning from the design of new compounds, also supported by molecular modeling techniques, their synthesis and characterization, and biological tests. In this context, the current crisis caused by the COVID-19 pandemic, but also older threats, such as the human immunodeficiency virus or the hepatitis C virus, require greater attention than ever. The research works described in this book provide an extremely useful example of the results achieved in the field of antibacterial drug development. The search for new chemical entities was approached starting from both natural and synthetic compounds and addressing different targets. In addition, recent findings were presented and discussed highlighting the strategies to fight bacterial resistance. Detailed references to the state-of-the-art can be found in this book. We strongly encourage the wide group of readers to explore the book that we are presenting, to get inspired to develop new approaches for the diagnosis and treatment of antibacterial diseases, and to circumvent resistance issues.

Download or read book Microbiotechnology Based Surfactants and Their Applications written by Pattanathu K.S.M. Rahman and published by Frontiers Media SA. This book was released on 2016-02-18 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosurfactants are structurally diverse group of bioactive molecules produced by a variety of microorganisms. They are secondary metabolites that accumulate at interfaces, reduce surface tension and form micellar aggregates. This research topic describes few novel microbial strains with a focus on increasing our understanding of genetics, physiology, regulation of biosurfactant production and their commercial potentials. A major stumbling block in the commercialization of biosurfactants is their high cost of production. Many factors play a significant role in making the process cost-effective and the most important one being the use of low-cost substrates such as agricultural residues for the production of biosurfactants. With the stringent government regulations coming into effect in favor of production and usage of the bio-based surfactants, many new companies aim to commercialize technologies used for the production of biosurfactants and to bring down costs. This Research Topic covers a compilation of original research articles, reviews and research commentary submitted by researchers enthusiastically working in the field of biosurfactants and highlights recent advances in our knowledge of the biosurfactants and understanding of the biochemical and molecular mechanisms involved in their production, scale-up and industrial applications. Apart from their diverse applications in the field of bioremediation, enhanced oil recovery, cosmetic, food and medical industries, biosurfactants can also boast off their unique eco-friendly nature to attract consumers and give the chemical surfactants a tough competition in the global market. This biosurfactant focused research topic aims to summarize the current achievements and explore the direction of development for the future generation of biosurfactants and bioemulsifiers. Some of the biosurfactant optimization processes presented are well-structured and already have a well-established research community. We wish to stimulate on-going discussions at the level of the biosurfactant production including common challenges in the process development, novel organisms and new feedstock and technologies for maximum benefit, key features of next generation biosurfactants and bioemulsifiers. We have compiled the research outputs of international leaders in the filed of biosurfactant particularly on the development of a state-of-the-art and highly-efficient process platform.

Download or read book Nanoporous Alumina written by Dusan Losic and published by Springer. This book was released on 2015-07-17 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives detailed information about the fabrication, properties and applications of nanoporous alumina. Nanoporous anodic alumina prepared by low-cost, simple and scalable electrochemical anodization process due to its unique structure and properties have attracted several thousand publications across many disciplines including nanotechnology, materials science, engineering, optics, electronics and medicine. The book incorporates several themes starting from the understanding fundamental principles of the formation nanopores and theoretical models of the pore growth. The book then focuses on describing soft and hard modification techniques for surface and structural modification of pore structures to tailor specific sensing, transport and optical properties of nano porous alumina required for diverse applications. These broad applications including optical biosensing, electrochemical DNA biosensing, molecular separation, optofluidics and drug delivery are reviewed in separated book chapters. The book appeals to researchers, industry professionals and high-level students.

Download or read book Biofuel Cells written by Inamuddin and published by John Wiley & Sons. This book was released on 2021-08-03 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid industrialization and urbanization associated with the environment changes calls for reduced pollution and thereby least use of fossil fuels. Biofuel cells are bioenergy resources and biocompatible alternatives to conventional fuel cells. Biofuel cells are one of the new sustainable renewable energy sources that are based on the direct conversion of chemical matters to electricity with the aid of microorganisms or enzymes as biocatalysts. The gradual depletion of fossil fuels, increasing energy needs, and the pressing problem of environmental pollution have stimulated a wide range of research and development efforts for renewable and environmentally friendly energy. Energy generation from biomass resources by employing biofuel cells is crucial for sustainable development. Biofuel cells have attracted considerable attention as micro- or even nano-power sources for implantable biomedical devices, such as cardiac pacemakers, implantable self-powered sensors, and biosensors for monitoring physiological parameters. This book covers the most recent developments and offers a detailed overview of fundamentals, principles, mechanisms, properties, optimizing parameters, analytical characterization tools, various types of biofuel cells, all-category of materials, catalysts, engineering architectures, implantable biofuel cells, applications and novel innovations and challenges in this sector. This book is a reference guide for anyone working in the areas of energy and the environment.

Download or read book Drug Discovery and Development E Book written by Raymond G Hill and published by Elsevier Health Sciences. This book was released on 2012-07-20 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern pharmacopeia has enormous power to alleviate disease, and owes its existence almost entirely to the work of the pharmaceutical industry. This book provides an introduction to the way the industry goes about the discovery and development of new drugs. The first part gives a brief historical account from its origins in the mediaeval apothecaries' trade, and discusses the changing understanding of what we mean by disease, and what therapy aims to achieve, as well as summarising case histories of the discovery and development of some important drugs. The second part focuses on the science and technology involved in the discovery process: the stages by which a promising new chemical entity is identified, from the starting point of a medical need and an idea for addressing it. A chapter on biopharmaceuticals, whose discovery and development tend to follow routes somewhat different from synthetic compounds, is included here, as well as accounts of patent issues that arise in the discovery phase, and a chapter on research management in this environment. The third section of the book deals with drug development: the work that has to be undertaken to turn the drug candidate that emerges from the discovery process into a product on the market. - The definitive introduction to how a pharmaceutical company goes about its business of discovering and developing drugs. The second edition has a new editor: Professor Raymond Hill ? non-executive director of Addex Pharmaceuticals, Covagen and of Orexo AB ? Visiting Industrial Professor of Pharmacology in the University of Bristol ? Visiting Professor in the School of Medical and Health Sciences at the University of Surrey ? Visiting Professor in Physiology and Pharmacology at the University of Strathclyde ? President and Chair of the Council of the British Pharmacological Society ? member of the Nuffield Council on Bioethics and the Advisory Council on Misuse of Drugs. New to this edition: - Completely rewritten chapter on The Role of Medicinal Chemistry in the Drug Discovery Process. - New topic - DMPK Optimization Strategy in drug discovery. - New chapter on Scaffolds: Small globular proteins as antibody substitutes. - Totally updated chapters on Intellectual Property and Marketing - 50 new illustrations in full colour Features - Accessible, general guide to pharmaceutical research and development. - Examines the interfaces between cost and social benefit, quality control and mass production, regulatory bodies, patent management, and all interdisciplinary intersections essential to effective drug development. - Written by a strong team of scientists with long experience in the pharmaceutical industry. - Solid overview of all the steps from lab bench to market in an easy-to-understand way which will be accessible to non-specialists. From customer reviews of the previous edition: '... it will have everything you need to know on this module. Deeply referenced and, thus, deeply reliable. - Highly Commended in the medicine category of the BMA 2006 medical book competition - Winner of the Royal Society of Medicine Library Prize for Medical Book of the Year

Download or read book Characterization of Minerals Metals and Materials 2019 written by Bowen Li and published by Springer. This book was released on 2019-02-13 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection gives broad and up-to-date results in the research and development of materials characterization and processing. Topics covered include characterization methods, ferrous materials, non-ferrous materials, minerals, ceramics, polymer and composites, powders, extraction, microstructure, mechanical behavior, processing, corrosion, welding, solidification, magnetic, electronic, environmental, nano-materials, and advanced materials The book explores scientific processes to characterize materials using modern technologies, and focuses on the interrelationships and interdependence among processing, structure, properties, and performance of materials.