Download or read book Characterization of Tumor Suppressive Role of DESC1 in Esophageal Squamous Cell Carcinoma written by 吳凱欣 and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Identification and Characterization of Tumor Suppressive Gene and Microrna in Esophageal Squamous Cell Carcinoma written by Kar-Lok Kong and published by Open Dissertation Press. This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Identification and Characterization of Tumor Suppressive Gene and MicroRNA in Esophageal Squamous Cell Carcinoma" by Kar-lok, Kong, 江家樂, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. DOI: 10.5353/th_b4645569 Subjects: Small interfering RNA Antioncogenes Esophagus - Cancer - Genetic aspects
Download or read book Identification and Characterization of Tumor Suppressive Gene and MicroRNA in Esophageal Squamous Cell Carcinoma written by Kar-lok Kong and published by . This book was released on 2011 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Characterization of Tumor Suppressing Function of PCAF in Esophageal Squamous Cell Carcinoma written by Cailei Zhu and published by . This book was released on 2007 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Characterization of Tumor Suppressing Function of PCAF in Esophageal Squamous Cell Carcinoma written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book New Research on Esophageal Cancer written by Henry K. Kinner and published by Nova Publishers. This book was released on 2007 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Esophageal cancer is a malignant tumour of the esophagus, the muscular tube that transports food from the mouth to the stomach. Esophageal cancer occurs most often in men over 50 years old. There are two main types of esophageal cancer, squamous cell carcinoma and adenocarcinoma. These two types are distinguished by the way they look under the microscope. Squamous cell cancer is associated with smoking and alcohol consumption. The incidence of this disease in the United States has remained relatively constant, while the incidence of adenocarcinoma of the esophagus has risen dramatically. Barrett's esophagus, a complication of gastroesophageal reflux disease (GERD), is a risk factor for the development of adenocarcinoma of the esophagus. Risk factors for adenocarcinoma of the esophagus include male gender, obesity, western diet, and smoking. This book presents new advances in this field of cancer research.
Download or read book Characterization of Two Candidate Tumor Suppressor Genes written by Hau-yi Lo (Paulisally) and published by . This book was released on 2011 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Esophageal Squamous Cell Carcinoma written by Nobutoshi Ando and published by Springer Nature. This book was released on 2020-06-17 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the second edition of the book, covering a wide spectrum of the latest information relevant to diagnosis and treatment of esophageal squamous cell carcinoma (ESCC). In recent years the incidence rate of esophageal cancer has been increasing; however, the background characteristics of the cancer treatment are significantly different between Asian and Western countries. In tumor histology, ESCC associated with smoking and alcohol consumption is overwhelmingly prevalent in Asia, whereas adenocarcinoma associated with Barrett’s metaplasia is remarkably prevalent in the West. In Asia, especially in Japan, surgeons play a significant role in the management of esophageal cancer patients, while medical and radiation oncologists as well as surgeons are important in the West. Considering these East–West differences in management of esophageal cancer, evidence originating in Asia should be more widely disseminated globally. The contributing authors, who have great expertise in their areas of specialization, discuss details in terms of treatment of ESCC, including basic science, diagnosis, surgery, other treatment modalities, Japanese guidelines, and also valuable experiences from other Asian countries. Accordingly, this excellent collection of texts benefits not only oncologists, but all medical and biological researchers involved in the latest ESCC research.
Download or read book Investigation of Tumor Suppressive Role of Chromosome 9 in Esophageal Squamous Cell Carcinoma written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Xvii, 144 leaves : ill. (some col.) ; 30 cm.
Download or read book Identification and Functional Analysis of Candidate Tumor Suppressor Genes in Chromosome 9 in Esophageal Squamous Cell Carcinoma ESCC written by Chun-lam Wong and published by . This book was released on 2010 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tumor Suppressive Role of Chromosomes 11 13 and 14 in Esophageal Squamous Cell Carcinoma Studied by Functional Complementation written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: HKUST Call Number: Thesis BIOL 2005 Ko.
Download or read book CHARACTERIZATION OF ONCOGENIC written by Qinghui Hu and published by Open Dissertation Press. This book was released on 2017-01-26 with total page 76 pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Characterization of Oncogenic Function of MicroRNA665 in Esophageal Squamous Cell Carcinoma" by Qinghui, Hu, 胡庆慧, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Background: Esophageal squamous cell carcinoma (ESCC) has been increasing in incidence, but knowledge of the genetic basis of this disease remains limited. In general, esophageal carcinoma can be divided into two main types: Esophageal Squamous Cell Carcinoma (ESCC) and Esophageal Adenocarcinoma (EAC). The pathogenesis of esophageal carcinoma still remains unclear, although some risk factors like chronic irritation, or chronic inflammation which may be caused by diseases such as gastroesophageal reflux disease (GERD) or unhealthy lifestyles like smoking have been proved to be related to the carcinogenic process. Diagnosis and treatment for this kind of cancer have continue to develop and evolve, but the 5-year overall survival rate is still relatively low. Therefore, it is clinically important to identify any potential genetic changes which may help us to discover some useful biomarker targets for the further development of more direct and harmless targeted therapy for our esophageal cancer patients. Objectives: In this study, I aimed to identify some potential oncogenic microRNA (miRNA) and to study their clinical meaning in ESCC patients. Methods: Microarray was applied to identify differentially expressed miRNAs in ESCC tumour tissue, compared with corresponding adjacent non-tumour esophageal tissue. One candidate oncogenic miRNA, miR-665, was investigated in the present study. After testing the expression level of miR-665 in ESCC cell lines and patients' samples with RT-PCR, miR-665 stably expressing cells was established using two ESCC cell lines (KYSE30 and KYSE510). Functional characterization was then conducted using in vitro and in vivo assays to examine the effect of miR-665 towards the development of ESCC. Bioinformatic software such as Target Scan was used to generate a list of predicted target genes that may be modulated by miR-665. Results: The high expression of miR-665 has been confirmed in ESCC tissues and cell lines, showing the potential carcinogenic function of miR-665. Ectopic expression of miR-665 also demonstrates its ability to enhance tumour growth and invasion in vitro and in vivo. Bioinformatic analysis of miR-665 predicted targets showed putative binding sites for miR-665 within the 3'UTR region of NLK. Conclusions: This study has identified a novel miRNA and a related gene which might play an important role in the pathogenesis of ESCC, affecting the cancer process and tumour growth. This may help to find potential new biomarker for the future improvement and development of new treatment of ESCC patients. DOI: 10.5353/th_b5108698 Subjects: Esophagus - Cancer - Genetic aspects Small interfering RNA
Download or read book Characterization of Plant Homeodomain Finger Protein 11 PHF11 a Candidate Tumor Suppressor in Esophageal Squamous Cell Carcinoma written by Wai-ying Cheung (M. Phil.) and published by . This book was released on 2012 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Identification and Characterization of Cancer related Genes in Esophageal Squamous Cell Carcinoma written by Li Fu (Ph. D.) and published by . This book was released on 2007 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Esophageal Cancer written by Nabil F. Saba and published by Springer Nature. This book was released on 2019-11-30 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this very successful book documents the latest progress in the prevention, diagnosis and treatment of esophageal cancer and includes additional sections covering novel targeted therapeutic approaches, immunotherapy and palliative and nutritional support for patients. Furthermore, the sections covering epidemiology, molecular biology, pathology, staging and radiologic and endoscopic assessments have been thoroughly updated and expanded. The principles of surgical resection, radiation therapy and systemic therapy are reviewed and attention is paid to the multidisciplinary approaches to the management of early stage cervical, thoracic, distal and junctional tumors. Updated information is also provided on the treatment of metastatic and recurrent disease as well as approaches that may impact future care, such as chemoprevention. Esophageal Cancer: Prevention, Diagnosis and Therapy will assist specialists from various disciplines, including surgery, radiation therapy, gastroenterology, medical oncology and palliative medicine, in delivering optimal, up-to-date care to the benefit of patients.
Download or read book Characterization of Plant Homeodomain Finger Protein 11 PHF11 a Candidate Tumor Suppressor in Esophageal Squamous Cell Carcinoma written by Wai-ying Cheung (M. Phil.) and published by . This book was released on 2012 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Oncogene Activation in Esophageal Cancer written by Alan G. Casson and published by R. G. Landes. This book was released on 1992 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oesophageal cancer is a particulary virulent gastrointestinal malignancy with poor prognosis. Changing patterns for this cancer have recently been observed in developed countries, and recently a 10% yearly increase in the rate of occurrence for primary adenocarcinoma of the oesophagus in North America was found, which exceeds that of any other malignancy. New techniques in molecular genetics have permitted the study of a number of human solid tumours at both the NDA and RNA levels, contributing significantly to our understanding of the multistep process of tumour development. This book reviews underlying molecular genetic events associated with the development of oesophageal cancer. The book also emphasizes the relationship of these events to other etiologic factors and premalignant conditions (such as Barrett's oesophagus).
