Download or read book Cellular and Molecular Mechanisms of Adipogenesis in Obesity written by Elise Cristine Jeffery and published by . This book was released on 2015 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Adipocyte and Obesity written by Charles H. Hollenberg and published by New York : Raven Press. This book was released on 1983 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: The proceedings of a 1982 international conference covers 33 review articles on research findings and the current state of knowledge of various metabolic and mechanistic aspects of the associations between the adipocyte fat cell and obesity. The articles address various facets of adipose cell growth and development; insulin action; lipid assimilation and lipoprotein and cholesterol metabolism in adipose tissue; lipolysis in adipocytes; and energy expenditure. The role of adipose tissue as a model system for the study of mechanisms of insulin action is highlighted by evidence of new cellular mediators. Recent insights in triglyceride assimilation regulation by lipoprotein lipase and fatty acid release through the lipolytic cascade are discussed. Other topics include the role of lipocytes in cholesterol turnover, the relationship of cholesterol metabolism to lipoprotein turnover and catabolism, and aspects of energy balance and thermoregulation in obesity. (wz).
Download or read book The Adipocyte and Obesity written by International Conference on the Adipocyte and Obesity. 1982, Toronto and published by . This book was released on 1983-01-01 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cellular and Biochemical Mechanisms of Obesity written by Paramjit S. Tappia and published by Springer Nature. This book was released on 2021-12-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Global health has been challenged with the dawning of the era of the obesity epidemic, and thus as a consequence, strategies to reduce obesity have become public health priorities. According to the United Nations, obesity has been identified as a concern for achieving Sustainable Development Goals. Obesity is a serious health problem with an increased risk of several common diseases including diabetes, cardiovascular disease, and cancer. Although the fundamental cause of obesity and overweight is an imbalance between calorie intake and calorie expenditure, the underlying biochemical and metabolic processes that cause obesity are not fully understood. Two earlier volumes dedicated to the subject of obesity, published in the series “Advances in Biochemistry in Health and Disease” focused on the pathophysiology of obesity-induced health complications and the biochemistry of cardiovascular dysfunction in obesity. This book brings together contributions from international experts in the field to describe advancements on the mechanisms leading to development of obesity and related complications. There are 21 chapters in two different parts in this book, comprising of Part I: Pathophysiologic Mechanisms of Obesity (11 chapters) and Part II: Therapeutic Mechanisms of Obesity (10 chapters). This book will serve as a resource and be of interest to health professionals, medical students, fellows, residents and graduate students. It will also evoke innovative research and effective approaches for the prevention of obesity. This volume will accentuate that obesity is a major health hazard in its own right and that appropriate public health measures should be implemented to prevent or reduce or even reverse the impact of this global chronic disease.
Download or read book Molecular Mechanisms Underpinning the Development of Obesity written by Clévio Nóbrega and published by Springer. This book was released on 2014-12-12 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a multi-factorial disease, in which an excess of accumulated body fat can reach levels capable of affecting health. It results from an interplay between environmental factors, eating behavior, genes, epigenetics, and neuronal stimuli. The main aim of this book is to provide a state-of-the-art revision about the molecular mechanisms underpinning the development of obesity, reviewing the current knowledge in areas like monogenic and polygenic obesity forms, but also providing an updated view of the emerging knowledge about epigenetics, nutrigenomics, and neuronal aspects that also contribute to obesity.
Download or read book The Adipocyte and Obesity Cellular and Molecular Mechanisms written by and published by . This book was released on 1983 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Physiology and Physiopathology of Adipose Tissue written by Jean-Philippe Bastard and published by Springer Science & Business Media. This book was released on 2012-11-28 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific advances in the physiology and pathophysiology of adipose tissue over the last two decades have been considerable. Today, the cellular and molecular mechanisms of adipogenesis are well known. In addition, adipose tissue is now recognized as a real endocrine organ that produces hormones such as the leptin acting to regulate food intake and energy balance in the central nervous system, a finding that has completely revolutionized the paradigm of energy homeostasis. Other adipokines have now been described and these molecules are taking on increasing importance in physiology and pathophysiology. Moreover, numerous works have shown that in obesity, but also in cases of lipodystophy, adipose tissue was the site of a local low-grade inflammation that involves immune cells such as macrophages and certain populations of lymphocytes. This new information is an important step in the pathophysiology of both obesity and related metabolic and cardiovascular complications. Finally, it is a unique and original work focusing on adipose tissue, covering biology and pathology by investigating aspects of molecular and cellular biology, general, metabolic, genetic and genomic biochemistry.
Download or read book Cellular and Molecular Mechanisms in the Recruitment of Immune Cells Into Adipose Tissue in Obesity written by Patricia Krinninger and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Molecular Mechanisms of Adipogenesis in Obesity and the Metabolic Syndrome written by Bettina Meissburger and published by . This book was released on 2010 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Mechanobiology of Obesity and Related Diseases written by Amit Gefen and published by Springer. This book was released on 2014-10-18 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes the state-of-knowledge in the study of the relationships between mechanical loading states in tissues and common pathophysiologies related to increase in mass of adipose tissues and/or hyperglycemia which eventually lead to obesity, diabetes, insulin resistance, hyperlipidemia, metabolic inflammations, certain types of cancer and other related diseases. There appears to be an interaction between the loading states in tissues and cells and these chronic conditions, as well as with factors such as age, gender and genetics of the individual. Bioengineering has made key contributions to this research field in providing technologies for cell biomechanics experimentation, microscopy and image processing, tissue engineering and multi-scale, multi-physics computational modeling. Topics at the frontier of this field of study include: the continuous monitoring of cell growth, proliferation and differentiation in response to mechanical factors such as stiffness of the extracellular matrix (ECM) and mechanical loads transferred through the ECM; mechanically-activated signaling pathways and molecular mechanisms; effects of different loading regimes and mechanical environments on differentiation fates of mesenchymal stem cells (MSCs) into myogenic and osteogenic versus adipogenic lineages; the interactions between nutrition and mechanotransduction; cell morphology, focal adhesion patterns and cytoskeletal remodeling changes in adipogenesis; activation of receptors related to diabetes by mechanical forces; brown and white adipose plasticity and its regulation by mechanical factors.
Download or read book Novel Insights into Adipose Cell Functions written by Karine Clément and published by Springer Science & Business Media. This book was released on 2010-09-14 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity is a disease of society and economic transition spreading at an epidemic pace throughout the world. According to the World Health Organization, obesity is defined as an increased or abnormal accumulation of body fat mass to the extent that individual’s health will be negatively affected. Overweight is thus being considered as top at risk condition in the world and it is mandatory to identify the physiopathological causes involved in adipose tissue enlargement and related metabolic and cardiovascular health disorders.This volume provides the most up to date insights into the biology of a complex endocrine organ: the adipose tissue.
Download or read book Angiogenesis in Adipose Tissue written by Yihai Cao and published by Springer Science & Business Media. This book was released on 2013-09-05 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Angiogenesis has recently played a critical role in regulation of adipose tissue expansion and regression. Like most other tissues in the body, adipose expansion and regression is accompanied by alteration of blood vessel density and structures. The vascular alteration plays an active role in regulation of adipose tissue size and functions. Targeting blood vessels in the adipose tissue have demonstrated to be a novel approach for possibly treatment of cancer, obesity and other metabolic diseases. This book provides the most updated information on this type research and discusses future opportunities for therapy..
Download or read book Tissue Specific Cell Signaling written by Joana Vieira Silva and published by Springer Nature. This book was released on 2020-05-29 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt: Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters. This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors. Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Download or read book Clinical Anatomy by Systems written by Richard S. Snell and published by Lippincott Williams & Wilkins. This book was released on 2007 with total page 964 pages. Available in PDF, EPUB and Kindle. Book excerpt: Included CD-ROM contains clinical notes, information on congenital anomalies, radiographic anatomy, and clinical problem-solving exercises, all of which correlate directly with the text.
Download or read book Obesity and Lipotoxicity written by Ayse Basak Engin and published by Springer. This book was released on 2017-06-05 with total page 618 pages. Available in PDF, EPUB and Kindle. Book excerpt: Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. “Lipotoxicity and Obesity” will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field.
Download or read book Adipose Tissue in Health and Disease written by Todd Leff and published by John Wiley & Sons. This book was released on 2010-03-19 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely and most comprehensive reference available on the topic covers all the different aspects vital in the fight against the global obesity epidemic. Following a look at adipose tissue development and morphology, the authors go on to examine its metabolic and endocrine functions and its role in disease. The final section deals with comparative and evolutionary aspects of the tissue. The result is an essential resource for cell and molecular biologists, physiologists, biochemists, pharmacologists, and those working in the pharmaceutical industry.
Download or read book Adipose Derived Stem Cells written by Jeffrey M. Gimble and published by Humana Press. This book was released on 2011-08-24 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the past decade, a wide range of scientific disciplines have adopted the use of adipose-derived stem/stromal cells (ASCs) as an important tool for research and discovery. In Adipose-Derived Stem Cells: Methods and Protocols, experts from the field, including members of the esteemed International Federation of Adipose Therapeutics and Science (IFATS), provide defined and established protocols in order to further codify the utilization of these powerful and accessible cells. With chapters organized around approaches spanning the discovery, pre-clinical, and clinical processes, much of the emphasis is placed on human ASC, while additional techniques involving small and large animal species are included. As a volume in the highly successful Methods in Molecular BiologyTM series, the detailed contributions include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Adipose-Derived Stem Cells: Methods and Protocols serves as a vital reference text for experienced researchers as well as new students on the path to further exploring the incredible potential of ASCs.
