Download or read book Causal Inference for Complex Longitudinal Data the Continuous Case written by R. D. Gill and published by . This book was released on 2001 with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Targeted Learning in Data Science written by Mark J. van der Laan and published by Springer. This book was released on 2018-03-28 with total page 655 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook for graduate students in statistics, data science, and public health deals with the practical challenges that come with big, complex, and dynamic data. It presents a scientific roadmap to translate real-world data science applications into formal statistical estimation problems by using the general template of targeted maximum likelihood estimators. These targeted machine learning algorithms estimate quantities of interest while still providing valid inference. Targeted learning methods within data science area critical component for solving scientific problems in the modern age. The techniques can answer complex questions including optimal rules for assigning treatment based on longitudinal data with time-dependent confounding, as well as other estimands in dependent data structures, such as networks. Included in Targeted Learning in Data Science are demonstrations with soft ware packages and real data sets that present a case that targeted learning is crucial for the next generation of statisticians and data scientists. Th is book is a sequel to the first textbook on machine learning for causal inference, Targeted Learning, published in 2011. Mark van der Laan, PhD, is Jiann-Ping Hsu/Karl E. Peace Professor of Biostatistics and Statistics at UC Berkeley. His research interests include statistical methods in genomics, survival analysis, censored data, machine learning, semiparametric models, causal inference, and targeted learning. Dr. van der Laan received the 2004 Mortimer Spiegelman Award, the 2005 Van Dantzig Award, the 2005 COPSS Snedecor Award, the 2005 COPSS Presidential Award, and has graduated over 40 PhD students in biostatistics and statistics. Sherri Rose, PhD, is Associate Professor of Health Care Policy (Biostatistics) at Harvard Medical School. Her work is centered on developing and integrating innovative statistical approaches to advance human health. Dr. Rose’s methodological research focuses on nonparametric machine learning for causal inference and prediction. She co-leads the Health Policy Data Science Lab and currently serves as an associate editor for the Journal of the American Statistical Association and Biostatistics.

Download or read book Targeted Learning written by Mark J. van der Laan and published by Springer Science & Business Media. This book was released on 2011-06-17 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the target parameter representing the scientific question of interest. This book is aimed at both statisticians and applied researchers interested in causal inference and general effect estimation for observational and experimental data. Part I is an accessible introduction to super learning and the targeted maximum likelihood estimator, including related concepts necessary to understand and apply these methods. Parts II-IX handle complex data structures and topics applied researchers will immediately recognize from their own research, including time-to-event outcomes, direct and indirect effects, positivity violations, case-control studies, censored data, longitudinal data, and genomic studies.

Download or read book Unified Methods for Censored Longitudinal Data and Causality written by Mark J. van der Laan and published by Springer Science & Business Media. This book was released on 2012-11-12 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fundamental statistical framework for the analysis of complex longitudinal data is provided in this book. It provides the first comprehensive description of optimal estimation techniques based on time-dependent data structures. The techniques go beyond standard statistical approaches and can be used to teach masters and Ph.D. students. The text is ideally suitable for researchers in statistics with a strong interest in the analysis of complex longitudinal data.

Download or read book Causal Inference written by Miquel A. Hernan and published by CRC Press. This book was released on 2019-07-07 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of causal inference methods is growing exponentially in fields that deal with observational data. Written by pioneers in the field, this practical book presents an authoritative yet accessible overview of the methods and applications of causal inference. With a wide range of detailed, worked examples using real epidemiologic data as well as software for replicating the analyses, the text provides a thorough introduction to the basics of the theory for non-time-varying treatments and the generalization to complex longitudinal data.

Download or read book Dynamic Mixed Models for Familial Longitudinal Data written by Brajendra C. Sutradhar and published by Springer Science & Business Media. This book was released on 2011-01-27 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a theoretical foundation for the analysis of discrete data such as count and binary data in the longitudinal setup. Unlike the existing books, this book uses a class of auto-correlation structures to model the longitudinal correlations for the repeated discrete data that accommodates all possible Gaussian type auto-correlation models as special cases including the equi-correlation models. This new dynamic modelling approach is utilized to develop theoretically sound inference techniques such as the generalized quasi-likelihood (GQL) technique for consistent and efficient estimation of the underlying regression effects involved in the model, whereas the existing ‘working’ correlations based GEE (generalized estimating equations) approach has serious theoretical limitations both for consistent and efficient estimation, and the existing random effects based correlations approach is not suitable to model the longitudinal correlations. The book has exploited the random effects carefully only to model the correlations of the familial data. Subsequently, this book has modelled the correlations of the longitudinal data collected from the members of a large number of independent families by using the class of auto-correlation structures conditional on the random effects. The book also provides models and inferences for discrete longitudinal data in the adaptive clinical trial set up. The book is mathematically rigorous and provides details for the development of estimation approaches under selected familial and longitudinal models. Further, while the book provides special cares for mathematics behind the correlation models, it also presents the illustrations of the statistical analysis of various real life data. This book will be of interest to the researchers including graduate students in biostatistics and econometrics, among other applied statistics research areas. Brajendra Sutradhar is a University Research Professor at Memorial University in St. John’s, Canada. He is an elected member of the International Statistical Institute and a fellow of the American Statistical Association. He has published about 110 papers in statistics journals in the area of multivariate analysis, time series analysis including forecasting, sampling, survival analysis for correlated failure times, robust inferences in generalized linear mixed models with outliers, and generalized linear longitudinal mixed models with bio-statistical and econometric applications. He has served as an associate editor for six years for Canadian Journal of Statistics and for four years for the Journal of Environmental and Ecological Statistics. He has served for 3 years as a member of the advisory committee on statistical methods in Statistics Canada. Professor Sutradhar was awarded 2007 distinguished service award of Statistics Society of Canada for his many years of services to the society including his special services for society’s annual meetings.

Download or read book Longitudinal Data Analysis written by Jason Newsom and published by Routledge. This book was released on 2013-06-19 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides accessible treatment to state-of-the-art approaches to analyzing longitudinal studies. Comprehensive coverage of the most popular analysis tools allows readers to pick and choose the techniques that best fit their research. The analyses are illustrated with examples from major longitudinal data sets including practical information about their content and design. Illustrations from popular software packages offer tips on how to interpret the results. Each chapter features suggested readings for additional study and a list of articles that further illustrate how to implement the analysis and report the results. Syntax examples for several software packages for each of the chapter examples are provided at www.psypress.com/longitudinal-data-analysis. Although many of the examples address health or social science questions related to aging, readers from other disciplines will find the analyses relevant to their work. In addition to demonstrating statistical analysis of longitudinal data, the book shows how to interpret and analyze the results within the context of the research design. The methods covered in this book are applicable to a range of applied problems including short- to long-term longitudinal studies using a range of sample sizes. The book provides non-technical, practical introductions to the concepts and issues relevant to longitudinal analysis. Topics include use of publicly available data sets, weighting and adjusting for complex sampling designs with longitudinal studies, missing data and attrition, measurement issues related to longitudinal research, the use of ANOVA and regression for average change over time, mediation analysis, growth curve models, basic and advanced structural equation models, and survival analysis. An ideal supplement for graduate level courses on data analysis and/or longitudinal modeling taught in psychology, gerontology, public health, human development, family studies, medicine, sociology, social work, and other behavioral, social, and health sciences, this multidisciplinary book will also appeal to researchers in these fields.

Download or read book Causal Inference Using Variation in Treatment Over Time written by Xinyao Ji and published by . This book was released on 2017 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: This thesis and related research is motivated by my interest in understanding the use of time-varying treatments in causal inference from complex longitudinal data, which play a prominent role in public health, economics, and epidemiology, as well as in biological and medical sciences. Longitudinal data allow the direct study of temporal changes within individuals and across populations, therefore give us the edge to utilize time this important factor to explore causal relationships than static data. There are also a variety challenges that arise in analyzing longitudinal data. By the very nature of repeated measurements, longitudinal data are multivariate in various dimensions and have completed random-error structures, which make many conventional causal assumptions and related statistical methods are not directly applicable. Therefore, new methodologies, most likely data-driven, are always encouraged and sometimes necessary in longitudinal causal inference, as will be seen throughout this thesis.As a result of the various topics explored, this thesis is split into four parts corresponding to three dierent patterns of variation in treatment. The rst pattern is the one-directional change of a binary treatment assignment, meaning that each study participant is only allowed to experience the change from untreated to treated at the staggered time. Such pattern is observed in a novel cluster-randomized design called the stepped-wedge. The second pattern is the arbitrary switching of a binary treatment caused by changes in person-specic characteristics and general time trend. The patterns is the most common thing one would observe in longitudinal data and we develop a method utilizing trends in treatment to account for unmeasured confounding. The third pattern is that the underlying treatment, outcome, covariates are time-continuous, yet are only observed at discrete time points. Instead of modeling cross-sectional and pooled longitudinal data, we take a mechanistic view by modeling reactions among variables using stochastic dierential equations and investigate whether it is possible to draw sensible causal conclusions from discrete measurements.

Download or read book The SAGE Handbook of Regression Analysis and Causal Inference written by Henning Best and published by SAGE. This book was released on 2013-12-20 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: ′The editors of the new SAGE Handbook of Regression Analysis and Causal Inference have assembled a wide-ranging, high-quality, and timely collection of articles on topics of central importance to quantitative social research, many written by leaders in the field. Everyone engaged in statistical analysis of social-science data will find something of interest in this book.′ - John Fox, Professor, Department of Sociology, McMaster University ′The authors do a great job in explaining the various statistical methods in a clear and simple way - focussing on fundamental understanding, interpretation of results, and practical application - yet being precise in their exposition.′ - Ben Jann, Executive Director, Institute of Sociology, University of Bern ′Best and Wolf have put together a powerful collection, especially valuable in its separate discussions of uses for both cross-sectional and panel data analysis.′ -Tom Smith, Senior Fellow, NORC, University of Chicago Edited and written by a team of leading international social scientists, this Handbook provides a comprehensive introduction to multivariate methods. The Handbook focuses on regression analysis of cross-sectional and longitudinal data with an emphasis on causal analysis, thereby covering a large number of different techniques including selection models, complex samples, and regression discontinuities. Each Part starts with a non-mathematical introduction to the method covered in that section, giving readers a basic knowledge of the method’s logic, scope and unique features. Next, the mathematical and statistical basis of each method is presented along with advanced aspects. Using real-world data from the European Social Survey (ESS) and the Socio-Economic Panel (GSOEP), the book provides a comprehensive discussion of each method’s application, making this an ideal text for PhD students and researchers embarking on their own data analysis.

Download or read book Inference for Functional Data with Applications written by Lajos Horváth and published by Springer Science & Business Media. This book was released on 2012-05-08 with total page 426 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents recently developed statistical methods and theory required for the application of the tools of functional data analysis to problems arising in geosciences, finance, economics and biology. It is concerned with inference based on second order statistics, especially those related to the functional principal component analysis. While it covers inference for independent and identically distributed functional data, its distinguishing feature is an in depth coverage of dependent functional data structures, including functional time series and spatially indexed functions. Specific inferential problems studied include two sample inference, change point analysis, tests for dependence in data and model residuals and functional prediction. All procedures are described algorithmically, illustrated on simulated and real data sets, and supported by a complete asymptotic theory. The book can be read at two levels. Readers interested primarily in methodology will find detailed descriptions of the methods and examples of their application. Researchers interested also in mathematical foundations will find carefully developed theory. The organization of the chapters makes it easy for the reader to choose an appropriate focus. The book introduces the requisite, and frequently used, Hilbert space formalism in a systematic manner. This will be useful to graduate or advanced undergraduate students seeking a self-contained introduction to the subject. Advanced researchers will find novel asymptotic arguments.

Download or read book Causal Inference written by Miguel A Hernan and published by . This book was released on 2023-08-15 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by pioneers in the field, this practical book presents an authoritative yet accessible overview of the methods and applications of causal inference. The text provides a thorough introduction to the basics of the theory for non-time-varying treatments and the generalization to complex longitudinal data.

Download or read book Causal Inference with Longitudinal Data Moving Beyond Difference in Difference written by Landon Manzano Gibson and published by . This book was released on 2020 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: Difference-in-Difference is a widely used method in health policy and health services research for estimating a causal effect. Unfortunately, the validity of difference-in-difference is difficult to evaluate without a tool to directly assess the parallel trends assumption. For example, existing tools indirectly examine the parallel trends assumption using pre-treatment observations. Developments in the methodological literature have given rise to an alternative class of estimators -- Synthetic Controls -- that do not make the parallel trends assumption and to sensitivity analysis tools that provide a novel approach for directly evaluating the parallel trends assumption The first chapter of this dissertation develops guidelines for the use of synthetic control methods alongside difference-in-difference. Synthetic control methods are a valuable tool because they don't assume parallel trends; however, they are not without assumptions of their own. This chapter provides guidance for the utilization of synthetic controls and difference-in-difference and proposes several post-estimation validity analyses to further evaluate the assumptions made by each method. The second chapter examines the effect of Medicaid Expansion on State Medicaid spending. The analysis is done using a subset of states among which the parallel trends assumptions is tenuous. Using a kernel-balanced synthetic control, and the post-estimation analyses introduced in the first chapter, this paper shows no evidence for Medicaid Expansion increasing or decreasing State Medicaid spending over a three-year period. The third chapter extends a suite of sensitivity tools for estimating the sensitivity of difference-in-difference to unobserved time-varying confounders -- parallel trends violations. The tools utilize the explanatory power of observed covariates to estimate how strong unobserved confounders must be to change the conclusions. They not only relax the strict binary nature of classic indirect parallel trends tests but also utilize the post-period outcome data to directly examine the parallel trends assumption.

Download or read book Linear Mixed Models for Longitudinal Data written by Geert Verbeke and published by Springer Science & Business Media. This book was released on 2009-05-12 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive treatment of linear mixed models for continuous longitudinal data. Next to model formulation, this edition puts major emphasis on exploratory data analysis for all aspects of the model, such as the marginal model, subject-specific profiles, and residual covariance structure. Further, model diagnostics and missing data receive extensive treatment. Sensitivity analysis for incomplete data is given a prominent place. Most analyses were done with the MIXED procedure of the SAS software package, but the data analyses are presented in a software-independent fashion.

Download or read book Explanation in Causal Inference written by Tyler J. VanderWeele and published by Oxford University Press, USA. This book was released on 2015 with total page 729 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive examination of methods for mediation and interaction, VanderWeele's book is the first to approach this topic from the perspective of causal inference. Numerous software tools are provided, and the text is both accessible and easy to read, with examples drawn from diverse fields. The result is an essential reference for anyone conducting empirical research in the biomedical or social sciences.

Download or read book Causal Inference and Dynamic Modelling in the Analysis of Longitudinal Data written by Aidan Gerard O'Keeffe and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Statistical Models in Epidemiology the Environment and Clinical Trials written by M.Elizabeth Halloran and published by Springer Science & Business Media. This book was released on 1999-10-29 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This IMA Volume in Mathematics and its Applications STATISTICAL MODELS IN EPIDEMIOLOGY, THE ENVIRONMENT,AND CLINICAL TRIALS is a combined proceedings on "Design and Analysis of Clinical Trials" and "Statistics and Epidemiology: Environment and Health. " This volume is the third series based on the proceedings of a very successful 1997 IMA Summer Program on "Statistics in the Health Sciences. " I would like to thank the organizers: M. Elizabeth Halloran of Emory University (Biostatistics) and Donald A. Berry of Duke University (Insti tute of Statistics and Decision Sciences and Cancer Center Biostatistics) for their excellent work as organizers of the meeting and for editing the proceedings. I am grateful to Seymour Geisser of University of Minnesota (Statistics), Patricia Grambsch, University of Minnesota (Biostatistics); Joel Greenhouse, Carnegie Mellon University (Statistics); Nicholas Lange, Harvard Medical School (Brain Imaging Center, McLean Hospital); Barry Margolin, University of North Carolina-Chapel Hill (Biostatistics); Sandy Weisberg, University of Minnesota (Statistics); Scott Zeger, Johns Hop kins University (Biostatistics); and Marvin Zelen, Harvard School of Public Health (Biostatistics) for organizing the six weeks summer program. I also take this opportunity to thank the National Science Foundation (NSF) and the Army Research Office (ARO), whose financial support made the workshop possible. Willard Miller, Jr.

Download or read book Simulation and Causal Inference Methods for Repeated Measures Or Longitudinal Data written by Alexander Levis and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "Several methods for estimating treatment effects in the presence of time-dependent confounding have been proposed for which asymptotic consistency results have been proven. To investigate finite-sample properties of these complex estimators, it is often necessary to use simulated data to benchmark performance. However, simulations in the literature have typically been simplistic, with no exhaustive comparison of available methods. We propose and implement a complex simulation study that compares a variety of popular causal methods in the longitudinal, repeated-measures setting. The causal methods investigated are then applied to data from a large cluster-randomized trial, the PROmotion of Breastfeeding Intervention Trial (PROBIT). Implications of the simulation study are discussed in the context of the current literature." --