Download or read book Oxygen Sensing written by and published by Elsevier. This book was released on 2004-05-10 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volume provides a comprehensive compendium of experimental approaches to the study of oxygen sensing in 48 chapters that are written by leaders in their fields.

Download or read book The Carotid Body Chemoreceptors written by Constancio Gonzalez and published by . This book was released on 1997 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Arterial Chemoreceptors written by Yoshiaki Hayashida and published by Springer Science & Business Media. This book was released on 2006-04-24 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents an updated review of the physiology of the carotid body chemoreceptors. It contains results in the topics at the frontiers of future developments in O2-sensing in chemoreceptor cells. Additionally, this volume provides data from studies carried out in other O2-sensing tissues including pulmonary vasculature and erythropoietin producing cells. It is a prime source of information and a guideline for arterial chemoreception researchers.

Download or read book Anesthesia for Otolaryngologic Surgery written by Basem Abdelmalak and published by Cambridge University Press. This book was released on 2012-10-18 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anesthesia for Otolaryngologic Surgery offers a comprehensive synopsis of the anesthetic management options for otolaryngologic and bronchoscopic procedures. Authored by world authorities in the fields of anesthesiology and otolaryngology, both theoretical concepts and practical issues are addressed in detail, providing literature-based evidence wherever available and offering expert clinical opinion where rigorous scientific evidence is lacking. A full chapter is dedicated to every common surgical ENT procedure, as well as less common procedures such as face transplantation. Clinical chapters are enriched with case descriptions, making the text applicable to everyday practice. Chapters are also enhanced by numerous illustrations and recommended anesthetic management plans, as well as hints and tips that draw on the authors' extensive experience. Comprehensively reviewing the whole field, Anesthesia for Otolaryngologic Surgery is an invaluable resource for every clinician involved in the care of ENT surgical patients, including anesthesiologists, otolaryngologists and pulmonologists.

Download or read book The Cerebral Circulation written by Marilyn J. Cipolla and published by Biota Publishing. This book was released on 2016-07-28 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

Download or read book Tumors of the Adrenal Gland and Extra adrenal Paraganglia written by Ernest E. Lack and published by American Registry of Pathology. This book was released on 1997 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Vascular Surgery written by George Geroulakos and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: A first class summary of the management principles of clinical cases in vascular surgery. With an international panel of contributors, many of whom are also examiners on the UK, European or American Boards of Vascular Surgery, this book familiarizes the reader quickly with day-to-day clinical practice. Case presentations are given in question and answer format and have been widely referenced to reassure the reader that the contents are established best practice. Each case is accompanied by 3 to 4 x-rays or color illustrations for visual clarity.

Download or read book Tumor Microenvironments in Organs written by Alexander Birbrair and published by Springer Nature. This book was released on 2020-02-06 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on the tumor microenvironment in over thirty human organs, including the parathyroid gland, heart, intestine, testicles, and more. Taken alongside its companion volumes, these books update us on what we know about the different aspects of the tumor microenvironments in distinct organs as well as future directions. Tumor Microenvironments in Organs: From the Brain to the Skin – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Download or read book Regulation of Tissue Oxygenation Second Edition written by Roland N. Pittman and published by Biota Publishing. This book was released on 2016-08-18 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.

Download or read book Neuroradiology written by Juan E. Small and published by Elsevier Health Sciences. This book was released on 2018-08-10 with total page 411 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acquire a better understanding of disease evolution and treatment response with Neuroradiology Spectrum and Evolution of Disease. The unique format includes carefully chosen clinical images that depict the pathologic evolution of disease from initial presentation across the continuum of progression. Colorful graphics plot characteristic changes, helping you visualize how normal and abnormal variations alter over time. Extensive illustrations and concise descriptions distill complex concepts, making this first-of-its-kind resource an excellent tool for imaging interpretation and clinical problem solving. - Presents neurologic disease from a novel imaging perspective, emphasizing evolutionary development and pointing out patterns to recognize. - Provides a state-of-the-art understanding of image interpretation based on early, middle, and late imaging characteristics; typical and atypical variants; and pre-treatment, post-treatment, progression, and regression characteristics. - Guides you through the progression of disease with chronological indicators, additional clinical images and descriptions, and annotations that highlight atypical findings – for an easy-to-digest, visually memorable presentation. - Helps you correctly interpret specific imaging characteristics you have never seen, even when the disease process is one you are familiar with.

Download or read book Carotid Body A New Target for Rescuing Neural Control of Cardiorespiratory Balance in Disease written by Rodrigo Del Rio and published by Frontiers Media SA. This book was released on 2016-12-12 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: The carotid body (CB) is in charge of adjusting ventilatory and cardiovascular function during changes in arterial blood gases. Regardless this essential function, the CB has been implicated in the sensing of other physiological signals such as changes in blood flow and glucose levels. More important, malfunction of the CB chemoreceptors has been associated with the progression and deterioration of several disease states such as hypertension, heart failure, renal failure, insulin resistance, diabetes and sleep apnea. Although the mechanisms involved in the alterations of the CB function in pathophysiology are currently under intense research, the development of therapeutic approaches to restore normal CB chemoreflex function remains unsolved. Recent studies showing the effect of CB denervation in pathophysiology have unveiled a key role of these arterial chemoreceptors in the development of autonomic imbalance and respiratory disturbances, and suggest that targeting the CB could represent a novel strategy to improve disease outcome. Unfortunately, classical pharmacotherapy intended to normalize CB function may be hard to establish since several cellular pathways are involved in the CB dysfunction. Augmented levels of angiotensin II, endothelin-1, cytokines and free radicals along with decreases in nitric oxide had all been related to the CB dysfunction. Moreover, changes in expression of angiotensin receptors, nitric oxide synthases and cytokines that take place within the CB tissue in pathological states also contribute to the enhanced CB chemoreflex drive. It has been shown in heart failure, hypertension and obstructive sleep apnea that the CB becomes tonically hyper-reactive. During the progression of the disease this CB chemosensory facilitation process induces central nervous system plasticity. The altered autonomic-respiratory control leads to increased cardiorespiratory distress and the deterioration of the condition. The focus of this e-book will be to cover the role of the CB in pathophysiology and to provide new evidence of the pathways involved in the maladaptive potentiation of the CB chemoreflex function. In memory of Professor Mashiko Shirahata and Professor Constancio Gonzalez.

Download or read book Anesthesiology Core Review written by Brian Freeman and published by McGraw Hill Professional. This book was released on 2014-07-06 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt: A rigorous, high-yield review for the new ABA Part 1: BASIC Examination The year 2014 marks the beginning of a new phase in board certification for anesthesiology residents in the United States. The Part 1 exam is now split into two written examinations: Basic and Advanced. Anesthesiology. Residents who are unable to pass the Basic examination will not be allowed to finish their training. That's why this book is a true must read for every anesthesiology resident. It is the single best way to take the stress out of this make-or-break exam, focus your study on nearly 200 must-know topics found on the board exam outline, and identify your areas of strength and weakness. Written by program directors with many years of board examination advising experience, Anesthesiology Core Review Part One: BASIC Exam is designed to be the cornerstone of your study preparation. Each chapter of Anesthesiology Core Review succinctly summarizes key concepts in basic science and clinical anesthesia practice. Space is conveniently provided throughout the book to add notes from other study resources. Anesthesiology Core Review Part One: BASIC Exam is logical divided into four sections: Basic Science Clinical Sciences Organ-Based Sciences Special Issues in Anesthesiology (covering important topics such as professionalism and licensure, ethics, and patient safety) With its expert authorship and concise yet thorough coverage, Anesthesiology Core Review Part One: BASIC Exam is biggest step you can take to assure effective preparation for the new ABA BASIC Examination.

Download or read book Morphofunctional and Neurochemical Aspects of the Mammalian Carotid Body written by Nikolai E. Lazarov and published by Springer Nature. This book was released on 2023-12-11 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of the book series Advances in Anatomy, Embryology and Cell Biology provides a complete and exhaustive overview of the morphofunctional organization of the mammalian carotid body, a polymodal chemosensory organ responsible for the maintenance of blood gas homeostasis. The authors review the state of the art of the neurochemical anatomy of carotid body ́s cell populations with a special reference to their structural and neurochemical plasticity. The essential role of this organ in the generation, progression and maintenance of cardiorespiratory and metabolic diseases in humans and other mammals is presented. Finally, the book summarizes current knowledge on the stem cell niche in the mammalian carotid body and discusses its contribution to replacement cell therapy and other potential applications in translational research. This book represents an essential reading for physiologists, anatomists, cell, and developmental biologists, as well as physicians, veterinarians, and biomedical researchers.

Download or read book Essential Clinical Anesthesia written by Charles Vacanti and published by Cambridge University Press. This book was released on 2011-07-11 with total page 1191 pages. Available in PDF, EPUB and Kindle. Book excerpt: The clinical practice of anesthesia has undergone many advances in the past few years, making this the perfect time for a new state-of-the-art anesthesia textbook for practitioners and trainees. The goal of this book is to provide a modern, clinically focused textbook giving rapid access to comprehensive, succinct knowledge from experts in the field. All clinical topics of relevance to anesthesiology are organized into 29 sections consisting of more than 180 chapters. The print version contains 166 chapters that cover all of the essential clinical topics, while an additional 17 chapters on subjects of interest to the more advanced practitioner can be freely accessed at www.cambridge.org/vacanti. Newer techniques such as ultrasound nerve blocks, robotic surgery and transesophageal echocardiography are included, and numerous illustrations and tables assist the reader in rapidly assimilating key information. This authoritative text is edited by distinguished Harvard Medical School faculty, with contributors from many of the leading academic anesthesiology departments in the United States and an introduction from Dr S. R. Mallampati. This book is your essential companion when preparing for board review and recertification exams and in your daily clinical practice.

Download or read book Carotid and Vertebral Artery Dissection written by Jodi Dodds and published by Createspace Independent Publishing Platform. This book was released on 2017-08-11 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Carotid and vertebral artery dissections are responsible for one-quarter of strokes in young adults. Despite this fact, there is very little awareness and understanding of these vascular injuries by the public, and even by healthcare providers. This book answers the common questions that patients with carotid and vertebral artery dissections have with easy-to-understand explanations. Also included are stories from patients who have persevered after their dissections. Their tales personalize dissection and stroke in young adults in an undeniable way, and illustrate the existence of the lingering effects dissections can have on patients for years. Jodi A. Dodds, MD, a vascular neurologist at Duke University, and Amanda P. Anderson, MS, CCC-SLP, a speech-language pathologist and a survivor of a severe carotid artery dissection, have created an important and needed resource for patients and their families as they navigate through the aftermath of this life-changing event.

Download or read book Resident Stem Cells and Regenerative Therapy written by Regina Coeli dos Santos Goldenberg and published by Academic Press. This book was released on 2012-09-26 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides explanations of experiments with animal models and clinical trials that are transforming the field of regeneration.

Download or read book CURRENT Procedures Surgery written by Rebecca Minter and published by McGraw Hill Professional. This book was released on 2010-05-28 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to perform more than 50 of the most common surgical procedures with this step-by-step, superbly illustrated guide! CURRENT Procedures Surgery is a unique combination atlas and text that details everything that you must know to perform more than 50 key surgical procedures. It covers the full spectrum of general surgery in an ultra-convenient, at-a-glance format, with more than 400 beautifully rendered illustrations to guide you every step of the way. An easy to follow template for each procedure includes: Indications, Contraindications, Informed Consent, Equipment, Patient Preparation, Patient Positioning, Procedure, Postoperative Care, Potential Complications, Pearls and Tips, References. Features: More than 400 illustrations created specifically for this book along with clear, concise text show you how to perform essential surgical procedures Coverage includes procedures for the breast, gastrointestinal tract, diaphragm, pancreas, liver, thyroid, parathyroid, adrenal, arteries and veins, and more Templated presentation facilitates rapid review Author's pearls and tips included for each procedure A must-have resource for anyone starting their surgical residency