Download or read book Cannabis and Khat in Drug Discovery written by Andrew G. Mtewa and published by Elsevier. This book was released on 2024-08-09 with total page 814 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cannabis and Khat in Drug Discovery: The Discovery Pipeline and the Endocannabinoid System provides comprehensive coverage of two important psychoactive plants: Khat and Cannabis. Initial research has found that compounds and derivatives from Cannabis and Khat are found to have promising properties that can be used for the discovery, design and development of potential drug leads against various diseases. This book extensively discusses the drug discovery and allied sciences of these compounds in the drug discovery pipeline, including basic research and computer aided modeling in ligand-drug interactions and their interactions with the endocannabinoid system. Categorized into sections including, chemical analyses and bioassays, medicinal chemistry, chemical biology and pharmacology, clinical applications, and policy and regulations, this book covers the methods and protocols involved and will be of interest to students, researchers, policymakers and all those involved in drug discovery research. - Covers the medicinal chemistry, pharmacology and biological chemistry of cannabis, khat, their constituent compounds and metabolites - Presents both the adverse and the beneficial entities to health and drug discovery - Includes detailed methods and protocol information to allow easy replication and application

Download or read book Cannabinoids and Pain written by Samer N. Narouze and published by Springer Nature. This book was released on 2021-07-01 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions. Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain. Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research. Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.

Download or read book Handbook of Cannabis and Related Pathologies written by Victor R Preedy and published by Academic Press. This book was released on 2016-12-31 with total page 1382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Cannabis and Related Pathologies: Biology, Pharmacology, Diagnosis, and Treatment is the first book to take an interdisciplinary approach to the understanding of cannabis use and misuse. Recent worldwide trends toward decriminalizing marijuana for medical use have increased legal use of the drug and recreational use remains high, making cannabis one of the most commonly used drugs. Cannabis has a wide range of adverse neurological effects, and use and abuse can lead to physical, social, and psychopathological issues that are multifarious and complex. Effective understanding and treatment requires knowledge of the drug's effects from across scientific disciplines. This book provides an overview of the biological and pharmacological components of the cannabis plant, outlines its neurological, social, and psychopathological effects, assists in the diagnosis and screening for use and dependency, and aids researchers in developing effective treatments for cannabis-related issues and disorders. Fully illustrated, with contributions from internationally recognized experts, it is the go-to resource for neuroscientists, pharmacologists, pathologists, public-health workers, and any other researcher who needs an in-depth and cross-disciplinary understanding of cannabis and its effects. - Comprehensive chapters include an abstract, key facts, mini dictionary of terms, and summary points - Presents illustrations with at least six figures, tables, and diagrams per chapter - Provides a one-stop-shopping synopsis of everything to do with cannabis and its related pathology, from chemicals and cells, individuals and communities, and diagnosis and treatment - Offers an integrated and informed synopsis of the complex issues surrounding cannabis as a substance, its use, and its misuse

Download or read book World Wide Weed written by Tom Decorte and published by Routledge. This book was released on 2016-02-11 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: For the majority of its history, the cultivation of cannabis did not stand out, at least compared to the cultivation of other illegal plants. Cannabis plantations, like coca bush or opium poppy plantations, were typically large in size, grown by local farmers in a handful of developing (producing) countries, processed and then exported to industrial (consuming) nations. While cocaine and heroin are still produced in a handful of developing countries, cannabis cultivation is increasingly universal. From Europe to the Americas and Oceania, import substitution in cannabis markets has been noticed in almost every developed country around the world, with a notable aversion for discrimination. Geographical, technological, cultural and economic factors help to explain why (indoor and outdoor) domestic cultivation is well established, and why the nature and extent of cultivation varies so dramatically across the western, developed nations. As we start the second decade of the 21st century, the new cannabis industry continues to fascinate both casual and academic observers of the drug scene. Researchers around the world have become increasingly interested in the phenomenon, aiming to describe, and potentially explain, the rapid switch from importation to domestic production in their own countries. In bringing together some of the world's leading experts on cannabis cultivation this book contains sixteen chapters that take an interdisciplinary look at global trends in cannabis cultivation. It will serve as an exemplar for wider discussions of key theories and concepts relating to the spread not just of cannabis cultivation, but also of illegal markets more generally, the actors that operate within these markets and the policies and practices that are employed in response to developments within these markets.

Download or read book A Comprehensive Guide to Toxicology in Preclinical Drug Development written by Ali S. Faqi and published by Academic Press. This book was released on 2012-11-02 with total page 904 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Preclinical Drug Development is designed for toxicologists who need a thorough understanding of the drug development process. This multi-contributed reference will provide a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics --

Download or read book Cannabis Legislation in Europe written by Brendan Hughes and published by . This book was released on 2018 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: "At a time of increased debate on the laws controlling the use of cannabis in the European Union, this report answers some of the questions most often asked about cannabis legislation. Using a question and answer format, basic definitions and the obligations of countries under international law are set out in a section on ‘What is cannabis and what are countries’ obligations to control it?‘ Two following sections examine the links and disparities between the content of the laws and their guidelines on the one hand and the actual implementation of the laws on the other. The final question and answer section considers whether changes in law have affected cannabis use and how much public support for legal change exists, as it looks at the future direction of cannabis legislation in Europe." -- Provided by publisher.

Download or read book A Comprehensive Guide to Toxicology in Nonclinical Drug Development written by Ali S. Faqi and published by Elsevier. This book was released on 2024-02-11 with total page 1074 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Third Edition is a valuable reference providing a complete understanding of all aspects of nonclinical toxicology in pharmaceutical research. This updated edition has been expanded and re-developed covering a wide-range of toxicological issues in small molecules and biologics. Topics include ADME in drug discovery, pharmacokinetics, toxicokinetics, formulations, and genetic toxicology testing. The book has been thoroughly updated throughout to reflect the latest scientific advances and includes new information on antiviral drugs, anti-diabetic drugs, immunotherapy, and a discussion on post-pandemic drug development challenges and opportunities. This is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. - Provides updated, unique content not covered in one comprehensive resource, including chapters on stem cells, antiviral drugs, anti-diabetic drugs, and immunotherapy - Includes the latest international guidelines for nonclinical toxicology in both small and large molecules - Incorporates practical examples in order to illustrate day-to-day activities and expectations associated with working in nonclinical toxicology

Download or read book Medical Toxicology of Drug Abuse written by Donald G. Barceloux and published by John Wiley & Sons. This book was released on 2012-02-03 with total page 1080 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a broad reference covering important drugs of abuse including amphetamines, opiates, and steroids. It also covers psychoactive plants such as caffeine, peyote, and psilocybin. It provides chemical structures, analytical methods, clinical features, and treatments of these drugs of abuse, serving as a highly useful, in-depth supplement to a general medical toxicology book. The style allows for the easy application of the contents to searchable databases and other electronic products, making this an essential resource for practitioners in medical toxicology, industrial hygiene, occupational medicine, pharmaceuticals, environmental organizations, pathology, and related fields.

Download or read book Novel Psychoactive Substances written by Ornella Corazza and published by Springer. This book was released on 2017-08-09 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of the recent emergence of Novel Psychoactive Substances (NPS) on a global scale, this book provides a timely analysis of the social and economic impact of the NPS phenomenon, and of the global policy and regulatory responses to it. It presents the first comprehensive overview of the international regulation, policy and market structure of the NPS phenomenon, offering a guide to inform legislative discussions and demonstrating from a comparative perspective the different approaches used to address the rise of NPS to date. It covers topics such as organized crime, drug markets, clinical evidence on NPS, and different regulatory approaches also in less explored settings such as prisons and sport environments. Overall, this highly informative and well-structured repository of different experiences with NPS policy, law and regulation offers an essential primary source of evidence for anyone interested in the area of drug and NPS policy, health economics and p ublic health.

Download or read book World Drug Report 2007 written by United Nations Office on Drugs and Crime and published by United Nations. This book was released on 2007-06-27 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report offers one of the most comprehensive insights into global trends in international culture, production, seizure and price of illicit drugs. It examines trends in the world's four major markets: opium and heroin, coca and cocaine, cannabis, and amphetamine-type stimulants. This edition provides an in-depth examination of the link between transnational organized crime and drug trafficking. A detailed statistical appendix on production, prices and consumption completes this book, which gives the reader a comprehensive picture of the world's drug problem.

Download or read book Routledge Handbook of Intoxicants and Intoxication written by Geoffrey Hunt and published by Taylor & Francis. This book was released on 2022-11-30 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together scholars from different disciplines in the humanities and social sciences, this multidisciplinary Handbook offers a comprehensive critical overview of intoxicants and intoxication. The Handbook is divided into 34 chapters across eight thematic sections covering a wide range of issues, including the meanings of intoxicants; the social life of intoxicants; intoxication settings; intoxication practices; alternative approaches to the study of intoxication; scapegoated intoxicants; discourses shaping intoxication; and changing notions of excess. It explores a range of different intoxicants, including alcohol, tobacco, coffee, tea, and legal and illicit drugs, including amphetamine, cannabis, ecstasy, khat, methadone, and opiates. Chapter length case studies explore these intoxicants in a variety of countries, including the USA, the UK, Australia, Bosnia & Herzegovina, Brazil, Denmark, Ireland, Japan, Kyrgyzstan, Nigeria, Singapore, and Sweden, across a broad timespan covering the nineteenth century to the present day. This wide-ranging Handbook will be of great interest to researchers, students, and instructors within the humanities and social sciences with an interest in a wide range of different intoxicants and different intoxication practices. Chapters 15 and 31 of this book are freely available as downloadable Open Access PDFs at http://www.taylorfrancis.com under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND)] 4.0 license.

Download or read book Drugs in Africa written by G. Klantschnig and published by Springer. This book was released on 2014-08-07 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This cutting-edge volume is the first to address the burgeoning interest in drugs and Africa among scholars, policymakers, and the general public. It brings together an interdisciplinary group of leading academics and practitioners to explore the use, trade, production, and control of mind-altering substances on the continent

Download or read book Poisonous Plants and Phytochemicals in Drug Discovery written by Andrew G. Mtewa and published by John Wiley & Sons. This book was released on 2020-12-04 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery - Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery - Written and edited by leading researchers in phytochemistry, medicinal chemistry, analytical chemistry, toxicology, and more - Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery Covers the mechanisms, benefits, risks and management protocols of phytotoxins in a scientific laboratory and the usefulness in drug discovery Presents chapters in a carefully designed, clear order, making it an ideal resource for the academic researcher or the industry professional at any stage in their career

Download or read book Forces of Habit written by David T. Courtwright and published by . This book was released on 2001-03-23 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: What drives the drug trade, and how has it come to be what it is today? A global history of the acquisition of progressively more potent means of altering ordinary waking consciousness, this book is the first to provide the big picture of the discovery, interchange, and exploitation of the planet’s psychoactive resources, from tea and kola to opiates and amphetamines.

Download or read book The Analytical Chemistry of Cannabis written by Brian F. Thomas and published by Elsevier. This book was released on 2015-12-01 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt: A volume in the Emerging Issues in Analytical Chemistry series, The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations provides analytical chemistry methods that address the latest issues surrounding cannabis-based products. The plethora of marketed strains of cannabis and cannabinoid-containing products, combined with the lack of industry standards and labelling requirements, adds to the general perception of poor quality control and limited product oversight. The methods described in this leading-edge volume help to support the manufacturing, labelling, and distribution of safe and consistent products with known chemical content and demonstrated performance characteristics. It treats analytical chemistry within the context of the diverse issues surrounding medicinal and recreational cannabis in a manner designed to foster understanding and rational perspective in non-scientist stakeholders as well as scientists who are concerned with bringing a necessary degree of order to a field now characterized by confusion and contradiction. - Addresses current and emerging analytical chemistry methods - an approach that is unique among the literature on this topic - Presents information from a broad perspective of the issues in a single compact volume - Employs language comprehensible to non-technical stakeholders as well as to specialists in analytical chemistry

Download or read book Kenyan Khat written by Neil C. M. Carrier and published by BRILL. This book was released on 2007 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed ethnography follows trajectories the controversial stimulant khat takes from Kenya's Nyambene Hills to consumers spread throughout the world, and highlights the great economic, social and cultural significance of this transnational commodity for those animating its 'social life'

Download or read book Cannabis written by Lucas Richert and published by MIT Press. This book was released on 2021-08-03 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cannabis consumption, commerce, and control in global history, from the nineteenth century to the present day. This book gathers together authors from the new wave of cannabis histories that has emerged in recent decades. It offers case studies from Africa, Asia, the Americas, Europe, and the Middle East. It does so to trace a global history of the plant and its preparations, arguing that Western colonialism shaped and disseminated ideas in the nineteenth century that came to drive the international control regimes of the twentieth. More recently, the emergence of commercial interests in cannabis has been central to the challenges that have undermined that cannabis consensus. Throughout, the determination of people around the world to consume substances made from the plant has defied efforts to stamp them out and often transformed the politics and cultures of using them. These texts also suggest that globalization might have a cannabis history. The migration of consumers, the clandestine networks established to supply them, and international cooperation on control may have driven much of the interconnectedness that is a key feature of the contemporary world.