Download or read book Building a Synapse written by George J. Wang and published by . This book was released on 2009 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Building up the inhibitory synapse written by Enrico Cherubini and published by Frontiers E-books. This book was released on with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fast inhibitory transmission exerts a powerful control on neuronal excitability and network oscillations thought to be associated with high cognitive functions. An alteration of inhibitory signaling is associated with major neurological and psychiatric disorders including epilepsy. Once released from presynaptic nerve terminals, GABA and glycine cross the synaptic cleft and bind to postsynaptic receptors localized in precise apposition to presynaptic release sites. The functional organization of inhibitory synapses consists in a dynamic process which relies on a number of highly specialized proteins that ensure the correct targeting, clustering, stabilization and subsequent fate of synaptic receptors. Among the proteins involved in this task, the tubulin-binding protein gephyrin plays a crucial role. Through its self-oligomerization properties, this protein forms hexagonal lattices that trap GABAA and glycine receptors and link them to the cytoskeleton. By directly interacting with cell-adhesion molecules of the neuroligin-neurexin families that connect presynaptic and postsynaptic neurons at synapses, gephyrin ensures a backward control of presynaptic signaling. In addition, changes in clusters size is dynamically regulated by lateral diffusion of neurotransmitter receptors between the synaptic and extrasynaptic compartments and by their interaction with synaptic scaffold proteins. The aim of this Research Topic (research articles and reviews) is to bring together experts on the cellular and molecular mechanisms regulating the appropriate assembly, location and function of pre and postsynaptic specializations at inhibitory synapses. A particular emphasis will be on the role of receptor trafficking in synaptic stabilization and plasticity.

Download or read book Limitless Analytics with Azure Synapse written by Prashant Kumar Mishra and published by Packt Publishing Ltd. This book was released on 2021-06-18 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leverage the Azure analytics platform's key analytics services to deliver unmatched intelligence for your data Key FeaturesLearn to ingest, prepare, manage, and serve data for immediate business requirementsBring enterprise data warehousing and big data analytics together to gain insights from your dataDevelop end-to-end analytics solutions using Azure SynapseBook Description Azure Synapse Analytics, which Microsoft describes as the next evolution of Azure SQL Data Warehouse, is a limitless analytics service that brings enterprise data warehousing and big data analytics together. With this book, you'll learn how to discover insights from your data effectively using this platform. The book starts with an overview of Azure Synapse Analytics, its architecture, and how it can be used to improve business intelligence and machine learning capabilities. Next, you'll go on to choose and set up the correct environment for your business problem. You'll also learn a variety of ways to ingest data from various sources and orchestrate the data using transformation techniques offered by Azure Synapse. Later, you'll explore how to handle both relational and non-relational data using the SQL language. As you progress, you'll perform real-time streaming and execute data analysis operations on your data using various languages, before going on to apply ML techniques to derive accurate and granular insights from data. Finally, you'll discover how to protect sensitive data in real time by using security and privacy features. By the end of this Azure book, you'll be able to build end-to-end analytics solutions while focusing on data prep, data management, data warehousing, and AI tasks. What you will learnExplore the necessary considerations for data ingestion and orchestration while building analytical pipelinesUnderstand pipelines and activities in Synapse pipelines and use them to construct end-to-end data-driven workflowsQuery data using various coding languages on Azure SynapseFocus on Synapse SQL and Synapse SparkManage and monitor resource utilization and query activity in Azure SynapseConnect Power BI workspaces with Azure Synapse and create or modify reports directly from Synapse StudioCreate and manage IP firewall rules in Azure SynapseWho this book is for This book is for data architects, data scientists, data engineers, and business analysts who are looking to get up and running with the Azure Synapse Analytics platform. Basic knowledge of data warehousing will be beneficial to help you understand the concepts covered in this book more effectively.

Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."

Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 399 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid

Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.

Download or read book Synapse Development and Maturation written by Pasko Rakic and published by Academic Press. This book was released on 2020-05-29 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synapse Development and Maturation, the latest release in the Comprehensive Developmental Neuroscience series, presents the latest information on the genetic, molecular and cellular mechanisms of neural development. The book provides a much-needed update that underscores the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on the synaptogenesis and developmental sequences in the maturation of intrinsic and synapse-driven patterns. - Features leading experts in various subfields as section editors and article authors - Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship - Includes coverage of mechanisms which regulate synapse formation and maintenance during development - Covers neural activity, from cell-intrinsic maturation, to early correlated patterns of activity

Download or read book Synapse written by Steven James and published by HarperChristian + ORM. This book was released on 2019-10-08 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thirty years in the future, when AI is so advanced that humans live side by side with cognizant humanoid robots called Artificials, Kestrel Hathaway must come to terms not just with what machines?know,?but with what they?believe. Soon after experiencing a personal tragedy, Kestrel witnesses a terrorist attack on a nearby artificial factory and is drawn into a world of conspiracies and lies that she and Jordan, her Artificial, have to untangle. With a second, more brutal attack looming on the horizon, their best chance of stopping it is teaming up with federal counterterrorism agent Nick Vernon. But the clock is ticking—and all the while, Jordan is asking questions Artificials were never meant to ask. Deftly weaving suspense and intrigue into a rich, resonant tale that explores faith and what it really means to be human, Steven James offers us a glimpse into the future—and into our own hearts. Synapse?is an unforgettable, gripping story of dreams shattered, truth revealed, and hope reborn. Praise for?Synapse: “Perfectly timed and thought-provoking,?Synapse?is a smart, intense thriller that keeps the suspense?building until the final page. Steven James once again delivers a perfect amalgam of character and?plot, totally immersing the reader in an irresistible narrative.” —Simon Gervais, international bestselling author of?Hunt Them Down “Next-level suspense that keeps the pages turning, combined with next-level writing on par?with the great literary masters . . .?Synapse?is not merely a thriller you should read—as 5G?approaches and advances in AI snowball, it is the thriller you can’t afford?not to.” —James R. Hannibal, award-winning author of?The Gryphon Heist

Download or read book Azure Data Factory by Example written by Richard Swinbank and published by Springer Nature. This book was released on with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synapse Construction in C Elegans written by Kerri Ann Spilker and published by Stanford University. This book was released on 2011 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specification and assembly of synapses is a highly coordinated and regulated process. Knowledge of the position and connectivity of all C. elegans neurons makes it a highly useful organism for studying the underlying mechanisms that control synapse formation. Using cell-specific promoters and fluorescently-labeled synaptic vesicle proteins, we are able to monitor synapse formation in subsets of C. elegans neurons. Close observation of synapse formation in a single posterior motorneuron (DA9) led to the identification of a mutation in the alternative splicing regulator mbl-1 that changes the synaptic pattern. The cholinergic motorneuron DA9 is required for backwards locomotion and forms ~25 synapses onto both inhibitory neurons and body wall muscles in the dorsal nerve cord (DNC) of the worm. We found that the 10 most distal synapses of DA9 fail to form in mbl-1 mutants, visualized with the synaptic vesicle-associated protein RAB-3 and the active zone proteins SYD-2/liprin-α and UNC-10/Rim. In addition, some RAB-3 mis-localizes to the dendrite of DA9 and animals have a backwards locomotion defect consistent with a loss of synapses onto dorsal body wall muscles. mbl-1 is a member of the conserved MBNL (Muscleblind like) family of CCCH zinc-finger RNA binding proteins that regulate alternative splicing of target genes by directly binding to target mRNA. In the human disease myotonic dystrophy type 1 (DM1), a progressive muscular dystrophy, sequestration of MBNL proteins in nuclear foci leads to altered splicing of downstream genes. Mis-splicing of several genes is responsible for the muscular and cardiac symptoms present in individuals with DM1. Most work on the MBNL proteins has focused on their role in muscle morphogenesis and maintenance. However, C. elegans mbl-1 is expressed in a subset of motorneurons including DA9 and is required cell autonomously in these neurons to regulate proper synapse formation. Post-synaptic and muscle markers were unaffected in mbl-1 mutant animals. Thus, our work demonstrates that mbl-1 also functions in neurons to regulate synapse formation. In a separate set of experiments, we identified a new mutation in the coding region of the touch cell-specific beta-tubulin, mec-7(wy116) that causes a defect in synapse formation in the mechanosensory neuron PLM. Previous studies have shown that mec-7 is expressed exclusively in the six touch neurons of C. elegans and is required for sensing light touch. Our mec-7 mutation leads to a loss of synaptic vesicle accumulation at PLM synaptic sites in the ventral nerve cord and synaptic vesicles are visible at ectopic locations along the lateral axon of PLM. Localization of the synaptic proteins VAMP and GIT-1 is also defective in our mutant, but neuronal morphology is wild-type. mec-7(wy116) is mildly Mec, but other alleles of mec-7 (e1506, e1527) do not phenocopy the synaptic vesicle localization defect. mec-7(wy116) is a missense mutation that alters a highly conserved Thr at position 409 to Ile. Crystal structures of tubulin indicate that this residue is on the face of tubulin that interacts with kinesin motor. Because we see synaptic vesicles along the lateral axon of PLM, we believe that kinesin-mediated vesicle transport is less efficient in mec-7(wy116) mutants.

Download or read book Building a Presynaptic Specialization written by Andrew Bennett Hellman and published by Stanford University. This book was released on 2011 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nervous system is comprised of a complex network of neurons that are connected by specialized structures called synapses. Each synapse contains a myriad of proteins that fulfill different functions, ranging from the release and reception of neurotransmitters to the maintenance and strengthening of the signals between neurons. Given the multitude of proteins present at the synapse, one question is how do they arrive and remain there? In my thesis, I use Caenorhabditis elegans to explore the cellular processes that contribute to the proper localization of important presynaptic proteins. In the first part of my thesis, I explored how presynaptic proteins are properly localized to the signal-sending process, called the axon, and excluded from the signalreceiving process, called the dendrite. In the motor neuron DA9, synaptic vesicles localize in a stereotyped region of the axon, but in cdk-5 mutants, 40% of the vesicle material is mislocalized to the dendrite. Chan-Yen Ou, a postdoctoral fellow in the lab, isolated a mutant that suppressed cdk-5, suggesting that the gene acts downstream or parallel to cdk-5. I mapped this mutant to the unc-101 locus, which encodes the μ- subunit of the AP1 complex. AP complexes are players in clathrin-mediated endocytosis, and the μ-subunit is the cargo recognition molecule within the complex. The AP1 complex plays a well-established role at the trans-golgi network in the cell body, but we present three results that suggest UNC-101 also acts at presynapses. The first result is the strong localization of UNC-101 at the synapse. The second result is that disrupting synaptic vesicle endocytosis (SVE) using genetic mutations causes a v similar phenotype as unc-101 mutations; animals mutant for unc-57/endophilin, unc- 26/synaptojanin, or dyn-1/dynamin 1 also suppress the cdk-5 dendritic phenotype. The third result is that the transport of synaptic vesicles from the synaptic region towards the dendrite decreases in an unc-101; cdk-5 double mutant compared to the cdk-5 single mutant, suggesting that UNC-101 is preventing retrograde flow from the synapses. While these results suggest a synaptic role for UNC-101, they do not exclude the possibility that UNC-101 also acts at the cell body. Indeed, I also show that UNC-101 affects the localization of postsynaptic proteins, which may occur by sorting proteins at the cell body. Additionally, postsynaptic proteins are unaffected by unc-57, suggesting an SVE-independent role for unc-101. Thus, I provide evidence that the AP1 subunit UNC-101 acts at presynapses and contributes to the molecular polarity of the DA9 motor neuron. The second part of my thesis contains my findings regarding a new system that I established to study synapse formation: the AFD thermosensory neuron. I found that the synaptic pattern in AFD is highly stereotyped, and I also isolated a mutant from a forward genetic screen that I mapped to the tax-4 locus. tax-4 and tax-2 encode two subunits of a cyclic nucleotide-gated channel that is necessary for sensory activity in AFD. When the genes are mutated, the localization of multiple presynaptic proteins is disrupted. Interestingly, they are not all similarly affected. Clusters of synaptic vesicles and the active zone protein SYD-2/liprin-α are dimmer and more numerous in tax-4 and tax-2 than wild-type animals. While SAD-1/SAD kinase clusters are also dimmer, there are fewer in tax-4 and tax-2 than wild-type animals. These results suggest that sensory activity can have different effects depending on the presynaptic vi protein. Thus, for the second part of my thesis, I describe the establishment of a new system to study synapse development, the results of a screen, and a link between neural activity and the localization of presynaptic proteins.

Download or read book Intercellular Communication in the Nervous System written by Robert Malenka and published by Academic Press. This book was released on 2010-05-22 with total page 777 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intercellular communication is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their environment is the basis of growth and development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, diabetes, and neurological and psychiatric disorders. There is substantial drug development concentrating on this and intercellular communication is the basis of much of neuropharmacology. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be yielded. Neurotransmitters/receptors, synaptic structure and organization, gap junctions, neurotrophic factors and neuropeptides are all explored in this volume, as are the ways in which signaling controls neuroendocrinology, neuroimmunology and neuropharmacology. Intercellular Communication in the Nervous System provides a valuable desk reference for all scientists who consider signaling. - Chapters offer impressive scope with topics addressing neurotransmitters/receptors, synaptic structure and organization, neuropeptides, gap junctions, neuropharmacology and more - Richly illustrated in full color with over 200 figures - Contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge

Download or read book How People Learn written by National Research Council and published by National Academies Press. This book was released on 2000-08-11 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: First released in the Spring of 1999, How People Learn has been expanded to show how the theories and insights from the original book can translate into actions and practice, now making a real connection between classroom activities and learning behavior. This edition includes far-reaching suggestions for research that could increase the impact that classroom teaching has on actual learning. Like the original edition, this book offers exciting new research about the mind and the brain that provides answers to a number of compelling questions. When do infants begin to learn? How do experts learn and how is this different from non-experts? What can teachers and schools do-with curricula, classroom settings, and teaching methodsâ€"to help children learn most effectively? New evidence from many branches of science has significantly added to our understanding of what it means to know, from the neural processes that occur during learning to the influence of culture on what people see and absorb. How People Learn examines these findings and their implications for what we teach, how we teach it, and how we assess what our children learn. The book uses exemplary teaching to illustrate how approaches based on what we now know result in in-depth learning. This new knowledge calls into question concepts and practices firmly entrenched in our current education system. Topics include: How learning actually changes the physical structure of the brain. How existing knowledge affects what people notice and how they learn. What the thought processes of experts tell us about how to teach. The amazing learning potential of infants. The relationship of classroom learning and everyday settings of community and workplace. Learning needs and opportunities for teachers. A realistic look at the role of technology in education.

Download or read book Azure Data Factory Cookbook written by Dmitry Anoshin and published by Packt Publishing Ltd. This book was released on 2020-12-24 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Solve real-world data problems and create data-driven workflows for easy data movement and processing at scale with Azure Data Factory Key FeaturesLearn how to load and transform data from various sources, both on-premises and on cloudUse Azure Data Factory’s visual environment to build and manage hybrid ETL pipelinesDiscover how to prepare, transform, process, and enrich data to generate key insightsBook Description Azure Data Factory (ADF) is a modern data integration tool available on Microsoft Azure. This Azure Data Factory Cookbook helps you get up and running by showing you how to create and execute your first job in ADF. You’ll learn how to branch and chain activities, create custom activities, and schedule pipelines. This book will help you to discover the benefits of cloud data warehousing, Azure Synapse Analytics, and Azure Data Lake Gen2 Storage, which are frequently used for big data analytics. With practical recipes, you’ll learn how to actively engage with analytical tools from Azure Data Services and leverage your on-premise infrastructure with cloud-native tools to get relevant business insights. As you advance, you’ll be able to integrate the most commonly used Azure Services into ADF and understand how Azure services can be useful in designing ETL pipelines. The book will take you through the common errors that you may encounter while working with ADF and show you how to use the Azure portal to monitor pipelines. You’ll also understand error messages and resolve problems in connectors and data flows with the debugging capabilities of ADF. By the end of this book, you’ll be able to use ADF as the main ETL and orchestration tool for your data warehouse or data platform projects. What you will learnCreate an orchestration and transformation job in ADFDevelop, execute, and monitor data flows using Azure SynapseCreate big data pipelines using Azure Data Lake and ADFBuild a machine learning app with Apache Spark and ADFMigrate on-premises SSIS jobs to ADFIntegrate ADF with commonly used Azure services such as Azure ML, Azure Logic Apps, and Azure FunctionsRun big data compute jobs within HDInsight and Azure DatabricksCopy data from AWS S3 and Google Cloud Storage to Azure Storage using ADF's built-in connectorsWho this book is for This book is for ETL developers, data warehouse and ETL architects, software professionals, and anyone who wants to learn about the common and not-so-common challenges faced while developing traditional and hybrid ETL solutions using Microsoft's Azure Data Factory. You’ll also find this book useful if you are looking for recipes to improve or enhance your existing ETL pipelines. Basic knowledge of data warehousing is expected.

Download or read book Stakeholder Management and Social Responsibility written by Ovidiu Nicolescu and published by Routledge. This book was released on 2021-12-24 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: The main objective of this book is to provide an innovative set of concepts and tools regarding company management, internal and external stakeholders and social responsibilities, reflecting the necessities and opportunities generated by the digital transformation, the transition to a knowledge-based economy, and the COVID-19 crisis. The book, based on a holistic vision and contextual approach of business, contributes to the development of company management and stakeholder and social responsibility theories and practices, being structured in 12 chapters. The original company management vision, approaches, and tools are based on three pillars: a new "manager–relevant stakeholder" rather than "manager–subordinate" managerial paradigm; a new type of company social responsibility rather than corporate social responsibility; and a new concept of company-relevant stakeholder rather than that of salient stakeholders. The book contains two innovative managerial mechanisms: the managerial synapse and company-relevant stakeholders-based management system able to help companies and stakeholders face successfully the challenges of digital transformation and the COVID-19 crisis and to generate greater organization functionality and performance. The book will be of interest to company managers and management specialists, management academics, consultants and researchers, and MBA students interested in a style of management with social responsibility at the forefront.

Download or read book Brain building Nutrition written by Michael A. Schmidt and published by Frog Books. This book was released on 2001 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised version of Smart Fats: How Dietary Fats and Oils Affect Mental, Physical, and Emotional Intelligence, has been considerably updated to reflect the current research in fatty acids and the brain. This includes new studies on the effects of stress on the fatty acids of the brain, data on depression, and studies on how saturated fat may impair learning and cognition. Included is a brief questionnaire on signs of fatty acid deficiency and intakes of helpful and harmful fats.

Download or read book The Modern Data Warehouse in Azure written by Matt How and published by Apress. This book was released on 2020-06-15 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: Build a modern data warehouse on Microsoft's Azure Platform that is flexible, adaptable, and fast—fast to snap together, reconfigure, and fast at delivering results to drive good decision making in your business. Gone are the days when data warehousing projects were lumbering dinosaur-style projects that took forever, drained budgets, and produced business intelligence (BI) just in time to tell you what to do 10 years ago. This book will show you how to assemble a data warehouse solution like a jigsaw puzzle by connecting specific Azure technologies that address your own needs and bring value to your business. You will see how to implement a range of architectural patterns using batches, events, and streams for both data lake technology and SQL databases. You will discover how to manage metadata and automation to accelerate the development of your warehouse while establishing resilience at every level. And you will know how to feed downstream analytic solutions such as Power BI and Azure Analysis Services to empower data-driven decision making that drives your business forward toward a pattern of success. This book teaches you how to employ the Azure platform in a strategy to dramatically improve implementation speed and flexibility of data warehousing systems. You will know how to make correct decisions in design, architecture, and infrastructure such as choosing which type of SQL engine (from at least three options) best meets the needs of your organization. You also will learn about ETL/ELT structure and the vast number of accelerators and patterns that can be used to aid implementation and ensure resilience. Data warehouse developers and architects will find this book a tremendous resource for moving their skills into the future through cloud-based implementations. What You Will LearnChoose the appropriate Azure SQL engine for implementing a given data warehouse Develop smart, reusable ETL/ELT processes that are resilient and easily maintained Automate mundane development tasks through tools such as PowerShell Ensure consistency of data by creating and enforcing data contracts Explore streaming and event-driven architectures for data ingestionCreate advanced staging layers using Azure Data Lake Gen 2 to feed your data warehouse Who This Book Is For Data warehouse or ETL/ELT developers who wish to implement a data warehouse project in the Azure cloud, and developers currently working in on-premise environments who want to move to the cloud, and for developers with Azure experience looking to tighten up their implementation and consolidate their knowledge