Download or read book Brain Metabolism and Cerebral Disorders written by Harold Edwin Himwich and published by . This book was released on 1976 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Metabolism and Cerebral Disorders written by Harold Edwin Himwich and published by . This book was released on 1951 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Diseases of the Brain Head and Neck Spine 2020 2023 written by Juerg Hodler and published by Springer Nature. This book was released on 2020-02-14 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.
Download or read book Brain Iron Metabolism and CNS Diseases written by Yan-Zhong Chang and published by Springer Nature. This book was released on 2019-08-27 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on advances in our understanding of the regulatory mechanisms of brain iron uptake, iron homeostasis and iron metabolism in the pathophysiology and pharmacology of CNS disease models. Dysregulation of brain iron homeostasis can lead to severe pathological changes in the neural system. Iron deficiency can slow down the development of the neural system and cause language and motion disorders, while iron overload is closely related to neurodegenerative diseases. Although some current books include chapters on iron metabolism and certain neurodegenerative diseases, this is the first systematic summary of the latest discoveries regarding brain iron metabolism and CNS diseases. By providing novel and thought-provoking insights into the mechanisms and physiological significance of brain iron metabolism and related diseases, the book stimulates further new research directions. It helps graduate students and researchers gain an overall picture of brain iron metabolism and the pathogenesis of neurodegenerative diseases, and also offers pharmaceutical companies inspiration for new treatment strategies for CNS diseases.
Download or read book Cerebral Blood Flow and Metabolism Measurement written by A. Hartmann and published by . This book was released on 1985-06-01 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Fluids and Metabolism written by Gary A. Rosenberg and published by . This book was released on 1990 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses new methods for dynamically assessing the brain function of patients with neurological diseases, describing such advanced techniques as positron emission tomography, nuclear magnetic resonance spectroscopy, and the autoradiographic analysis of transport, metabolism and receptor binding. The book adopts the clinician's point of view, and provides the background needed to understand the rapid advances in our understanding of brain metabolism. It aims to explain how these new techniques are used in assessing neurological disorders of metabolism.
Download or read book Circulatory and Developmental Aspects of Brain Metabolism written by M. Spatz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cerebral Blood Flow Relationship of Cerebral Blood Flow and Metabolism to Neurological Symptoms written by and published by . This book was released on 1972 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Chemistry of Brain Metabolism in Health and Disease written by Juda Hirsch Quastel and published by Springfield, Ill. : Thomas. This book was released on 1961 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Metabolic Inflammatory Axis in Brain Aging and Neurodegeneration written by Fei Yin and published by Frontiers Media SA. This book was released on 2017-08-16 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Impairment of energy metabolism is a hallmark of brain aging and several neurodegenerative diseases, such as the Alzheimer’s disease (AD). Age- and disease-related hypometabolism is commonly associated with oxidative stress and they are both regarded as major contributors to the decline in synaptic plasticity and cognition. Neuroinflammatory changes, entailing microglial activation and elevated expression of inflammatory cytokines, also correlate with age-related cognitive decline. It is still under debate whether the mitochondrial dysfunction-induced metabolic deficits or the microglia activation-mediated neuroinflammation is the initiator of the cognitive changes in aging and AD. Nevertheless, multiple lines of evidence support the notion that mitochondrial dysfunction and chronic inflammation exacerbate each other, and these mechanistic diversities have cellular redox dysregulation as a common denominator. This research topic focuses on the role of a metabolic-inflammatory axis encompassing the bioenergetic activity, brain inflammatory responses and their redox regulation in healthy brain aging and neurodegenerative diseases. Dynamic interactions among these systems are reviewed in terms of their causative or in-tandem occurrence and how the systemic environment, –e.g., insulin resistance, diabetes, and systemic inflammation–, impacts on brain function.
Download or read book Brain Disorders in Critical Illness written by Robert D. Stevens and published by Cambridge University Press. This book was released on 2013-09-19 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain dysfunction is a major clinical problem in intensive care, with potentially debilitating long-term consequences for post-ICU patients of any age. The resulting extended length of stay in the ICU and post-discharge cognitive dysfunction are now recognized as major healthcare burdens. This comprehensive clinical text provides intensivists and neurologists with a practical review of the pathophysiology of brain dysfunction and a thorough account of the diagnostic and therapeutic options available. Initial sections review the epidemiology, outcomes, relevant behavioral neurology and biological mechanisms of brain dysfunction. Subsequent sections evaluate the available diagnostic options and preventative and therapeutic interventions, with a final section on clinical encephalopathy syndromes encountered in the ICU. Each chapter is rich in illustrations, with an executive summary and a helpful glossary of terms. Brain Disorders in Critical Illness is a seminal reference for all physicians and neuroscientists interested in the care and outcome of severely ill patients.
Download or read book Pathophysiology of Cerebral Energy Metabolism written by B. B. Mrsulja and published by Springer. This book was released on 1979-05 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Energy Metabolism written by Bo K. Siesjö and published by John Wiley & Sons. This book was released on 1978 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Functional Mapping of the Brain in Vascular Disorders written by W.-D. Heiss and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the contributions to the symposium "Functional Mapping of the Brain in Vascular Disorders", held at the Thirteenth World Congress of Neurology, Sep tember 1-6, 1985 in Hamburg, FRG. I have to thank the contributors to this symposium for submitting their manu scripts long before the congress so that the printed procee dings could be distributed to the audience. I hope that this will enable the participants in this symposium not only to recall the vivid presentation of the lectures and the highlights of the discussions, but also to widen their knowlegde of the topics dealt with during the symposium by rereading the chapters on the various issues. I would also like to express my thanks to the company UCB, Kerpen, FRG, who sup ported the symposium and the printing of these proceedings. W.-D. HEISS Cologne, July 1985 Contents The Purpose of Functional Mapping in Focal Cerebral Ischemia W.-D. Heiss ... 1 Positron Emission Tomography Versus Nuclear Magnetic Resonance Imaging? M.M. Ter-Pogossian (With 1 Figure) ... 5 Aims on Phosphorus-3l Magnetic Resonance Imaging K. Kogure, H. Ohtomo, S. Matsui, and H. Kohno (With 10 Figures) ... 15 In Vivo Nuclear Magnetic Resonance Imaging of Sodium-23 in the Human Head S.K. Hilal, A.A. Maudsley, J.B. Ra, H.E. Simon, P. Roschmann, S. Wittekoek, Z.H. Cho, and S.K. Mun (With 5 Figures) ... 29 Uncoupling of Flow and Metabolism in Infarcted Tissue T. Jones, R.J.S. Wise, R.S.J. Frackowiak, J.M.
Download or read book Glycerophospholipids in the Brain written by Akhlaq A. Farooqui and published by Springer. This book was released on 2014-09-16 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a comprehensive description of phospholipid metabolism in brain, activities of phospholipases A2, and their involvement in neurological disorders. The purpose of this book is to present readers with cutting edge information in a lively manner that is useful not only to student and teachers but also to researchers and physicians.
Download or read book Interaction Between the Metabolism of Ketone Bodies in Brain Tissue and Neurological Disorders written by Chan-Chih Hsiao and published by . This book was released on 2020 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulation of brain metabolism and cerebral blood flow involves complex control systems with several interacting variables at both cellular and organ levels. Quantitative understanding of the spatially and temporally heterogeneous brain control mechanisms during internal and external stimuli requires the development and validation of a computational (mathematical) model of metabolic processes in brain tissue. A computational model of the biochemical pathways in brain is presented in this paper. The model structure consists of neurons, astrocytes, and a surrounding capillary network. Glucose is the major oxidative energy substrate in the brain. However, under hypoglycemic conditions such as during diet or fasting or other conditions induced by pathology, alternate energy substrates such as ketone bodies supplement glucose metabolism. In this study, the increased activity of the glutamate-glutamine shuttle is studied in conjunction with the observation that ketosis results in lower lactate levels in brain. A model of ketosis in brain is used to examine the partitioning of carbon units entering the tricarboxylic acid cycle at the level of acetyl-CoA. Using Flux Balance Analysis, we hypothesized that the carbon fluxes would shift towards an increase in flux rates stemming from the metabolism of ketone bodies with a proportional decrease in the flux of lactate derived from the astrocyte-neuron lactate shuttle. It was found that the model could predict an estimation of compartmentalized flux-balances (mitochondrial-cytosolic) in standard and ketogenic diet conditions. Ketone body metabolism was found to be loosely coupled with glucose metabolism (astrocyte-neuron) suggesting important therapeutic implications.
Download or read book Cerebral Blood Flow Metabolism and Head Trauma written by Christian W. Kreipke and published by Springer. This book was released on 2014-09-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written to satisfy a wide audience, from basic scientist to clinical researcher, this volume explores such varied concepts as: the influence of CBF in the pathotrajectory of TBI, modeling TBI as a means to understand underlying pathological states associated with brain injury victims, disrupted vasculature following head trauma and advanced imaging techniques, vasoreactive substances underlying disrupted blood flow, the role of age and sex on injury outcome, and the latest pre-clinical rationale for focusing on CBF and strategies to improve blood flow as a means to improve outcome in patients suffering the effects of TBI.
