Download or read book Brain Cancer Tumor Targeting and Cervical Cancer written by Elena K. Salvatti and published by Nova Science Publishers. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gathers research from across the globe in the study of brain cancer, cervical cancer and tumour targeting. This book discusses topics such as emerging targets in cancer therapy and novel nanotechnology-based therapeutic strategies that have been changing the paradigm in cancer treatment, and laparascopy and robotics in cervical cancer treatment.
Download or read book Resistance to Targeted Therapies Against Adult Brain Cancers written by Amanda Tivnan and published by Springer. This book was released on 2016-11-26 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.
Download or read book Emerging Therapeutic Targets in Brain Cancer written by Terrance Johns and published by Frontiers Media SA. This book was released on 2022-05-25 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain and Human Body Modeling 2020 written by Sergey N. Makarov and published by Springer Nature. This book was released on 2021 with total page 395 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.
Download or read book Nanopharmaceuticals Principles and Applications Vol 3 written by Vinod Kumar Yata and published by Springer Nature. This book was released on 2020-08-19 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.
Download or read book Brain Tumor Targeting Drug Delivery Systems Advanced Nanoscience for Theranostics Applications written by Ram Kumar Sahu and published by Bentham Science Publishers. This book was released on 2023-09-02 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain Tumor Targeting Drug Delivery Systems: Advanced Nanoscience for Theranostics Applications is a comprehensive reference focused on the latest advancements in nanotechnology for brain tumor therapy. With practical insights and cutting-edge research, this book equips readers with the knowledge to develop innovative drug delivery systems for effective brain tumor diagnosis and treatment. Structured into insightful chapters, this book covers the anatomy, physiology, and pathophysiology of the brain, addressing barriers to targeted drug delivery strategies. Chapters explore theranostics-based delivery systems, including polymeric nanoparticles, liposomes, dendrimers, nanoemulsions, micelles, and inorganic nanoparticles, for precise brain tumor diagnosis and treatment. This informative resource is designed for students and research scholars in pharmacology, pharmaceutical industry scientists, professors, and clinical medicine researchers. With comprehensive chapters and references for further reading, this book facilitates easy understanding of the intricate nanomedical technology, empowering researchers to make significant strides in the field of brain tumor therapy. Key Features: Structured chapters for easy understanding of nanotechnology concepts In-depth coverage of theranostics-based delivery systems for brain tumor diagnosis and treatment References for further reading and exploring new advances in drug delivery systems
Download or read book Brain Tumor Imaging written by Elke Hattingen and published by Springer. This book was released on 2015-09-02 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.
Download or read book Nanocarriers for Drug Targeting Brain Tumors written by Lalit Kumar and published by Elsevier. This book was released on 2022-06-21 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanocarriers for Drug-Targeting Brain Tumors covers different types of nanocarriers and their design and development for targeting drugs to the brain. The book also presents case studies and the mechanism of action of nanocarriers in drug targeting to a specific site. This helps researchers and clinicians understand the design, development and mechanism of action of nanocarriers. As brain tumors continue to be a significant health problem globally, and very complex for targeting drugs, conventional dosage forms are not very effective and side-effects are a major concern. Functionalized nanocarriers can address these problems. Furthermore, the targeting of nanocarriers is preferred for reducing toxicity and improving the effectiveness of the drugs. However, there is a need for understanding the design and development of formulation with the mechanism of action of nanocarriers for brain targeting. Provides information on the design and development of nanocarriers for targeting brain tumors Outlines the working principles of different nanocarriers for targeting brain tumors Includes case studies of different nanocarriers for targeting brain tumors
Download or read book Cancer as a Metabolic Disease written by Thomas Seyfried and published by John Wiley & Sons. This book was released on 2012-05-18 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.
Download or read book Metastatic Cancer Clinical and Biological Perspectives written by Rahul Jandial and published by CRC Press. This book was released on 2013-08-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.
Download or read book Brain Metastases written by Jeffrey Raizer and published by Springer Science & Business Media. This book was released on 2007-10-03 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.
Download or read book The pH Miracle written by Robert O. Young and published by Grand Central Life & Style. This book was released on 2008-11-16 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forget counting calories, fat grams, and cholesterol. Forget blood pressure, blood sugar, and hormone levels. The single most important health measurement is the pH level in your blood. Now, The pH Miracle unlocks the surprisingly crucial role pH balance plays in weight loss. How acidic or alkaline your blood is (pH levels) directly affects your health and is controlled by diet. For example, if the blood becomes overly acidic from eating too much of the wrong kinds of food -- wheat, bananas, meats, and cheese -- it can lead to weight gain, diabetes, heart disease, cancer, and more. The Youngs' program includes over 50 recipes and explains which foods to eat, which to avoid, and which supplements can help on the way towards optimal health and weight loss. In just weeks, readers will find they have more energy and a stronger immune system, and will have shed pounds and inches.
Download or read book CRISPR Cas Enzymes written by and published by Academic Press. This book was released on 2019-01-25 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Updated release includes the latest information on the CRISPR-Cas Enzymes
Download or read book Chu 1 written by John Layman and published by Image Comics. This book was released on 2020-07-22 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: "THE FIRST COURSE," Part One TONY CHU is a cibopath, able to get psychic impressions from what he eats. SAFFRON CHU is a cibopars, able to learn secrets from who she eats with. Tony is a cop. Saffron is a criminal. They are brother and sister, and they are on a collision course. Spinning out of the multiple Eisner Award-winning and New York Times bestselling series CHEW comes CHU, a felonious new food noir about cops, crooks, cooks, and clairvoyants.
Download or read book Nanotechnology and Functional Materials for Engineers written by Yaser Dahman and published by Elsevier. This book was released on 2017-01-13 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology and Functional Materials for Engineers focuses on key essentials and examples across the spectrum of nanomaterials as applied by engineers, including nanosensors, smart nanomaterials, nanopolymers, and nanotubes. Chapters cover their synthesis and characteristics, production methods, and applications, with specific sections exploring nanoelectronics and electro-optic nanotechnology, nanostructures, and nanodevices. This book is a valuable resource for interdisciplinary researchers who want to learn more about how nanomaterials are used in different types of engineering, including electrical, chemical, and biomedical. Offers in-depth information on a variety of nanomaterials and how they are used for different engineering applications Provides an overview of current research and suggests how this will impact future applications Explores how the unique properties of different nanomaterials make them particularly suitable for specific applications
Download or read book Cisplatin written by Bernhard Lippert and published by John Wiley & Sons. This book was released on 1999 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: 30 years after its discovery as an antitumor agent, cisplatin represents today one of the most successful drugs in chemotherapy. This book is intended to reminisce this event, to take inventory, and to point out new lines of development in this field. Divided in 6 sections and 22 chapters, the book provides an up-to-date account on topics such as - the chemistry and biochemistry of cisplatin, - the clinical status of Pt anticancer drugs, - the impact of cisplatin on inorganic and coordination chemistry, - new developments in drug design, testing and delivery. It also includes a chapter describing the historical development of the discovery of cisplatin. The ultimate question - How does cisplatin kill a cell? - is yet to be answered, but there are now new links suggesting how Pt binding to DNA may trigger a cascade of cellular reactions that eventually result in apoptosis. p53 and a series of damage recognition proteins of the HMG-domain family appear to be involved. The book addresses the problem of mutagenicity of Pt drugs and raises the question of the possible relevance of the minor DNA adducts, e.g. of interstrand cross-links, and the possible use of trans-(NH3)2Pt(II)-modified oligonucleotides in antisense and antigene strategies. Our present understanding of reactions of cisplatin with DNA is based upon numerous model studies (from isolated model nucleobases to short DNA fragments) and application of a large body of spectroscopic and other physico-chemical techniques. Thanks to these efforts there is presently no other metal ion whose reactions with nucleic acids are better understood than Pt. In a series of chapters, basic studies on the interactions of Pt electrophiles with nucleobases, oligonucleotides, DNA, amino acids, peptides and proteins are reported, which use, among others, sophisticated NMR techniques or X-ray crystallography, to get remarkable understanding of details on such reactions. Reactivity of cisplatin, once bound to DNA and formerly believed to be inert enough to stay, is an emerging phenomenon. It has (not yet) widely been studied but is potentially extremely important. Medicinal bioinorganic chemistry - the role of metal compounds in medicine - has received an enormous boost from cisplatin, and so has bioinorganic chemistry as a whole. There is hardly a better example than cisplatin to demonstrate what bioinorganic chemistry is all about: The marriage between classic inorganic (coordination) chemistry and the other life sciences - medicine, pharmacy, biology, biochemistry. Cisplatin has left its mark also on areas that are generally considered largely inorganic. The subject of mixed-valance Pt compounds is an example: From the sleeping beauty it made its way to the headlines of scientific journals, thanks to a class of novel Pt antitumor agents, the so-called "platinum pyrimidine blues". In the aftermath diplatinum (III) compounds were recognized and studies in large numbers, and now an organometalic chemistry of these diplatinum (III) species is beginning to emerge. The final section of the book is concerned with new developments such as novel di- and trinuclear Pt(II) drugs with DNA binding properties different from those of cisplatin, with orally active Pt(IV) drugs which are presently in clinical studies, and with attempts to modify combinatorial chemistry in such a way that it may become applicable to fast screening of Pt antitumor drugs. The potential of including computational methods in solving questions of Pt-DNA interactions is critically dealt with in the concluding chapter.
Download or read book Radioimmunotherapy Translational Opportunities and Challenges written by Udo S. Gaipl and published by Frontiers Media SA. This book was released on 2020-03-13 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt:
