Download or read book Principles of Bone Regeneration written by Jona J. Sela and published by Springer Science & Business Media. This book was released on 2012-03-13 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Regeneration is a timely publication that addresses the modern aspects of bone healing and repair. This exciting new volume details the convergence of the different experimental and clinical approaches designed for the study and treatment of bone healing in its diverse forms and under varying conditions. Bone healing is affected by a multitude of genetic, environmental, mechanical, cellular and endocrine variables which eventually lead to changes in gene expression that enhance the guided action of osteoblasts (and chondroblasts) to lay down bone that restores, or even improves, the skeletal load bearing capacity. Recent breakthroughs in understanding the regulatory aspects of bone formation and resorption, in both research and clinical arenas offer new modalities to induce, enhances and guide repair processes in bone for the benefit of millions of patients with conditions such as nonunion fractures, critical size defects, orthodontic tooth movement, periodontal bone loss, intraosseous implants and deformed bones.
Download or read book Bone Formation written by Felix Bronner and published by Springer Science & Business Media. This book was released on 2004 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone research in recent years has generated much new knowledge, in large measure because of the broad public health implications of osteoporosis and related bone disorders. Bone Formation, the first in a series entitled Topics in Bone Biology, evaluates this new information and formulates novel insights and hypotheses within the broad framework of current knowledge. An easy-to handle and to read work, with concise reviews that are extensively referenced, the chapters in this book are written by internationally known authorities. Particular emphasis is on osteoporosis and related disorders of diminished bone formation. Among the general topics treated is a chapter on biomechanical aspects of bone formation, not often considered in relation to diseases of bone formation. The book constitutes essential reading for those entering the field of bone biology and those who wish to become familiar with up-to-date information in a particular area of bone research.
Download or read book Bone Regeneration and Repair written by Jay R. Lieberman and published by Springer Science & Business Media. This book was released on 2007-10-27 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.
Download or read book Bone Reformation written by Stefan Lundgren (D.D.S.) and published by . This book was released on 2008 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bone Resorption written by Felix Bronner and published by Springer Science & Business Media. This book was released on 2005-07 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reflects the meteoric increase in knowledge regarding bone remodeling including molecular understanding of osteoclast development, regulatory molecules such as cytokines, pathophysiology and pharmaceutical development to treat osteoclast function. Rapid publication of an up-to-date volume addressing these issues by experts in the field, an asset to any library of clinical endocrinologists and rheumatologists, is a valuable read for those entering the scientific arena of bone remodeling research. It integrates recent technological advances with foundation data to provide a comprehensive view of bone resorption, and also links information gained from the genetic and molecular to the physiological and clinical levels. It is addressed to clinical practitioners, nutrition scientists, researchers and students, who seek a fundamental understanding of this important subject. An invaluable publication for the community of medical specialists- internists, endocrinologists, nephrologists, orthopaedists- as well as dental, paramedical and nursing practitioners.
Download or read book Bone Remodeling Process written by Rabeb Ben Kahla and published by Academic Press. This book was released on 2021-08-14 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bone Remodeling Process: Mechanics, Biology, and Numerical Modeling provides a literature review. The first part of the book discusses bones in a normal physiological condition, bringing together the involved actors and factors reported over the past two decades, and the second discusses pathological conditions, highlighting the attack vectors of each bone disease. The third part is devoted to the mathematical descriptions of bone remodeling, formulated to develop models able to provide information that is not amenable to direct measurement, while the last part focuses on models using the finite element method in investigating bone biomechanics.This book creates an overall image of the complex communication network established between the diverse remodeling actors, based on overwhelming control evidence revealed over recent years, as well as visualizes the remodeling defects and possible treatments in each case. It also regroups the models allowing readers to analyze and assess bone mechanical and biological properties. This book details the cellular mechanisms allowing the bone to adapt its microarchitecture to the requirements of the human body, which is the main issue in bone biology and presents the evolution of mathematical modeling used in a bone computer simulation. Each chapter covers a core topic in bone biomechanics Provides a multidisciplinary view that effectively links orthopaedics, cellular biology, mechanics, and computer simulation Draws an overall image about bone biology and cell interactions, for identifying cell populations that are crucial for the remodeling process
Download or read book Bone Health and Osteoporosis written by United States Public Health Service and published by . This book was released on 2004-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Download or read book Bone Remodelling and its Disorders written by Gregory R Mundy and published by CRC Press. This book was released on 1999-01-01 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abnormalities in bone remodelling occur in some of the most common diseases, including osteoporosis, cancer and Paget's disease, and cause considerable suffering This book bridges the gap between cellular and molecular biology, and pathophysiology and treatment This practical and succinct text will be of interest for all those involved in the study, diagnosis and treatment of bone disease
Download or read book Bone Biology and Healing written by Glyn O. Phillips and published by World Scientific. This book was released on 2003 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes succinctly the factors which affect the incorporation of massive and morsellised allografts after transplantation. Unless special precautions are taken, massive allografts when implanted can undergo stress fatigue. due to the limited incorporation at the graft-host interface. Immunological and cell signalling growth factors can be shown to greatly influencnce the behaviour of the graft. The bone-biological processes are illustrated in terms of demineralised bone, which can initiate bone induction due to the protection and availability of the original bone-morphogenic protein. The main message is that transplantation without consideration of the underlying biological healing processes can reduce the effectiveness of the procedure. Contents: The Biology of Massive Bone Allografts; Immunology of Bone Grafts: Current Knowledge; The Application of Growth Factors to Enhance Bone Healing; Biology of Healing of Large Deep-Frozen Cortical Bone Allografts; The Effect of Growth Factors on Bone Allografts; The Effect of Growth Factors on Bone Healing and the Clinical Applications of Autogenous Platelet-Rich Plasma Gel to Enhance Bone Formation; Biology of Demineralised Bone and Its Clinical Use. Readership: Orthopaedic surgeons who use tissue allografts in bone and related reconstructions.
Download or read book Mechanics of Cellular Bone Remodeling written by Qing-Hua Qin and published by CRC Press. This book was released on 2013-01-08 with total page 323 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on bone remodeling has resulted in much new information and has led to improvements in design and biomedical practices. Mechanics of Cellular Bone Remodeling: Coupled Thermal, Electrical, and Mechanical Field Effects presents a unified exploration of recent advances, giving readers a sound understanding of bone remodeling and its mathematical representation. Beginning with a description of the basic concept of bone remodeling from a mathematical point of view, the book details the development of each of the techniques and ideas. From there it progresses to the derivation and construction of multifield and cellular bone remodeling and shows how they arise naturally in response to external multifield loads. Topics include: Fundamental concepts and basic formulations for bone remodeling Applications of formulations to multifield internal bone remodeling of inhomogeneous long cylindrical bone Theory and solution of multifield surface bone remodeling A hypothetical regulation mechanism on growth factors for bone modeling and remodeling under multifield loading The RANK–RANKL–OPG pathway and formulation for analyzing the bone remodeling process A model of bone cell population dynamics for cortical bone remodeling under mechanical and pulsed electromagnetic stimulus Recent developments in experiments with bone materials Readers will benefit from the thorough coverage of general principles for each topic, followed by detailed mathematical derivations and worked examples, as well as tables and figures where appropriate. The book not only serves as a reliable reference but is also destined to attract interested readers and researchers to a field that offers fascinating and technologically important challenges.
Download or read book The Whole Body Approach to Osteoporosis written by R. McCormick and published by New Harbinger Publications. This book was released on 2009-05-01 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: No pill will cure you of osteoporosis. While medication can sometimes help, it won't fully address the underlying causes of your osteoporosis or osteopenia. To restore bone health, you'll need a targeted program combining the best bone-building strategies from traditional and holistic medicine. The Whole-Body Approach to Osteoporosis distills these complex strategies into a whole-body plan you can begin today to dramatically improve your bone strength and overall vitality. This comprehensive guide includes information on: What to eat for stronger bones Choosing bone-building supplements and osteoporosis medications Foods and medications that may be contributing to bone loss Signs and symptoms that can help you monitor your bone health How lab tests can help you personalize your plan
Download or read book Bone Morphogenetic Protein And Collagen An Advances In Tissue Banking Specialist Publication written by Glyn O Phillips and published by World Scientific. This book was released on 2004-01-16 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: What are bone morphogenetic proteins (BMPs) and how can they be used in orthopaedic practice? Ever since Urist proposed in 1976 that protein factors from cortical bone appeared to modulate bone healing in animals, there has been a search for these mysterious osteoinductive components. Now that their structure has been elucidated, they have been purified and cloned, and are now available for the improvement of bone healing.The best source of BMPs is demineralised bone. This bone allograft is used to achieve greater osteoinductive capacity. But are the actions of procurement, processing, demineralisation and sterilisation harmful to the BMPs? Unless the BMPs can be assayed, neither their clinical nor their scientific effectiveness can be appraised. All these aspects are logically and scientifically described in this volume. In addition, there is a review of the biochemistry of one of the two main components of bone, namely collagen. This subject is itself a confusing but rapidly growing field. This comprehensive review describes the procedures for building up bone in vivo and in vitro.Bone Morphogenetic Protein and Collagen answers most of the questions of orthopaedic surgeons and tissue bankers on how BMPs can be produced and used to their maximum effectiveness.
Download or read book Bone Regeneration with Bone Substitutes written by Bernd-Dietrich Katthagen and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: Congenital and acquired bone defects constitute a central problem of traumatology and orthopedics. In order to cure these defects it is often necessary to fill up the bones operatively with suitable substances. Recently, so-called bone substitutes (collagen, gelatine, bone matrix, calcium phospate, hydroxyapatite) have also been recommended. Following an introductory presentation of bone regeneration and transplants, these substitutes are discussed here in a comprehensive survey of the literature. Particular attention is given to the significance of mineral substance such as hydroxyapatite, which will undoubtedly find a place in bone surgery owing to its outstanding bioactivity and biotolerance. The implants examined are also of significance for maxillofacial surgery and dentistry. The histologic techniques in the staining of undecalcified bone preparations and in histomorphometry are presented in a special chapter.
Download or read book Skeletal Development and Remodeling in Health Disease and Aging Volume 1068 written by Mone Zaidi and published by Wiley-Blackwell. This book was released on 2006-06-23 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our understanding of how the skeleton is remodeled and repaired has been enormously expanded in the past decade. Using advanced molecular technologies including transgenesis, gene knockout, and gene array, we are gaining a better understanding of both the precise pathways through which osteoblasts lay down new bone and how osteoclasts remove old bone. These studies have not only helped us understand the basic biological properties of the skeleton and how it responds to hormonal, cytokine, and mechanical stimulation, but also, in some instances, clarified the source of pathophysiology. The eventual goal of such discoveries is to lay down a firm scientific foundation for the identification of novel cellular and molecular targets for future drug development. This volume presents the significant headway that scientists have made in this undertaking and the book is organized around four broad themes: skeletal development and repair, molecular endocrinology of bone, bone cell biology, and conservation of skeletal integrity. Also included are papers that focus on current and emerging therapies for osteoporosis. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.
Download or read book Advanced Techniques in Bone Regeneration written by Alessandro Rozim Zorzi and published by BoD – Books on Demand. This book was released on 2016-08-31 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.
Download or read book Radionuclide and Hybrid Bone Imaging written by Ignac Fogelman and published by Springer. This book was released on 2013-01-03 with total page 1029 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, written by authors with national and international reputations in the field, covers all aspects of radionuclide and hybrid bone imaging. Introductory sections present the basic science and consider the current status and limitations of conventional radiological techniques. The underlying principles of PET-CT and SPECT-CT are carefully explained, and the value of different PET and SPECT tracers, assessed. The role of single- and dual-modality approaches in the imaging of benign bone diseases and malignancies is then discussed in detail in a series of well-illustrated chapters. The pathologies addressed include metabolic bone disease, arthritis, bone and joint infections, primary bone and soft tissue tumors, and metastases from breast and prostate cancer. A further section considers the role of bone scintigraphy in the pediatric patient, and the closing chapters focus on miscellaneous subjects, including bone densitometry and radionuclide targeted therapy.
Download or read book Novel Molecules that Regulate Bone Formation and Bone Resorption written by Gabriel Robert Linares and published by . This book was released on 2011 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
