Download or read book Bladder Cancer A Cinderella Cancer Advances and Remaining Research Questions written by Mieke Van Hemelrijck and published by Frontiers Media SA. This book was released on 2020-11-18 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Cross Everything written by Henry Scowcroft and published by Bloomsbury Publishing. This book was released on 2021-02-18 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'A moving, compelling and vital book, that sheds much needed light on the very latest understanding of cancer.' - Siddhartha Mukherjee, author of The Emperor of All Maladies 'A gripping, heartbreaking, accessible personal journey through love and cancer' - Charles Graeber, New York Times bestselling author of The Breakthrough 'Sensitive and informed. Essential reading for anyone supporting a loved one through cancer. Heartbreaking, emotional – and totally and utterly uplifting and hopeful.' - Deborah James (@bowelbabe), writer and broadcaster 'May be the most heartbreaking medical memoir you'll read.' - Daily Mail ---- An extraordinary memoir that explores the further reaches of today's cancer science – alongside a deeply tender story of loss, grief and love. When Henry Scowcroft's partner Zarah was diagnosed with stage IV bladder cancer in her mid-thirties, their world fell apart. In order to cope with the upheaval as they endured scans, aggressive chemotherapy and hospital stays, Henry began writing down and sharing their experiences with friends and family. His day job as a writer for the charity Cancer Research UK helped him to explain everything he was learning from the coalface of cancer treatment – including Zarah's diagnosis, and their rollercoaster journey through the health system. After Zarah's untimely death Henry found some closure and comfort by trying to learn more about her cancer from scientific analysis of the test results and biopsies taken during her treatment, and enlisted a team of doctors and researchers to help him. Could he have done more? How did Zarah's tumour develop? Could there be a legacy from her death that would help others diagnosed with cancer? This heart-wrenching memoir of love and loss is interspersed with Henry's mission to understand the cancer that took his partner too soon.
Download or read book Rare Tumors and Tumor like Conditions in Urological Pathology written by Antonio Lopez-Beltran and published by Springer. This book was released on 2014-11-14 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to rare tumors and tumor-like conditions of the urinary system and male genital organs. It comprises five chapters, devoted to the kidney, bladder, prostate, testes, and penis. Each chapter begins with a brief overview of “common” tumors and tumor-like conditions and with a section on the classification of both common and rare entities. The main clinical, pathological, immunohistochemical, and molecular findings for each rare tumor or tumor-like condition are then described and discussed. Significant characteristics are also documented by representative high-quality illustrations, with emphasis on those aspects of most relevance to differential diagnosis. In addition, prognostic features are fully covered. Urological Pathology: Rare Tumors and Tumor-Like Conditions will be ideal source of core information and practical guidance for residents, fellows, pathologists, urologists, and oncologists.
Download or read book Uses of Epidemiology written by Jeremy Noah Morris and published by Longman Publishing Group. This book was released on 1975 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Let s Talk Lymphoedema written by Peter Mortimer and published by Elliott & Thompson. This book was released on 2017-05-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphoedema results from a failure of the lymphatic system, causing swelling and fluid retention; it can also cause aching, heaviness and difficulty moving. Research shows that around 140 million people worldwide may be living with lymphoedema, and it affects approximately one in five women after breast cancer treatment. There is no cure for the disease, but there are ways to control the symptoms. Let's Talk Lymphoedema has been written to help sufferers deal with its debilitating effects, providing information and inspiration to help them lead rich, vibrant lives. It features contributions from international experts and personalities such as Miriam Stoppard, and the actress Kathy Bates, who herself suffers from the condition. Including essential medical information (immune system and infection; microsurgery; obesity; podiatry); treatment advice (compression garments; physiotherapy; exercises); and day-to-day support (psychology, sexuality and others' perceptions), this is an essential read for sufferers, friends, family and medical professionals alike.
Download or read book MHC Class I Loss and Cancer Immune Escape written by Federico Garrido and published by Springer. This book was released on 2019-05-28 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the escape strategies used by cancer cells to avoid the immune response of the host. The main characters of this story are the “Antigen Presenting Molecules” and the “T Lymphocytes”. The former are known as the Major Histocompatibility Complex (MHC): the H-2 and the HLA molecules. The latter are a subgroup of white cells travelling all over our body which are capable to distinguish between “self and non self”. Readers will know from the inside about the history of the HLA genetic system and will discover how T lymphocytes recognize and destroy cancer cells. One of the key important questions is: Why tumors arise, develop and metastasize? This book tries to answer this question and will explain how cancer cells become invisible to killer T lymphocytes. The loss of the HLA molecules is a major player in this tumor escape mechanism. Cancer immunotherapy is aimed at stimulating T lymphocytes to destroy tumor cells. However, the clinical response rate is not as high as expected. The molecular mechanisms responsible for MHC/HLA antigen loss play a crucial role in this resistance to immunotherapy. This immune escape mechanism will be discussed in different types of tumors: lung, prostate, bladder and breast...ect. as well as melanoma and lymphoma. This book will be useful to Oncologists, Pathologists and Immunologist that will enter this fascinating area of research. It will be also interesting for biologist, doctoral students and medical residents interested in “Tumor Immunology”.
Download or read book CRISPR Cas Enzymes written by and published by Academic Press. This book was released on 2019-01-25 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Updated release includes the latest information on the CRISPR-Cas Enzymes
Download or read book ABC of Urology written by Chris Dawson and published by John Wiley & Sons. This book was released on 2009-04-08 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: Urological problems encompass a wide range of both distressing andpotentially life threatening conditions and the number of generalpractice presentations is growing rapidly due to the increasing ageof the population. Both reliable and comprehensive, the secondedition of the ABC of Urology provides a thoroughly updatedand revised guide to the speciality which highlights the recentadvances in this area. Concentrating specifically on the treatmentand diagnosis of the most common conditions, the emphasis is onshared care, where the skills of the primary care team are used inconjunction with hospital referral. This concise, well-illustrated and highly practical text willprovide the perfect reference for general practitioners andpractice nurses, as well as junior doctors handling hospitalreferrals.
Download or read book Pathology of the Urinary Bladder written by Antonio Lopez-Beltran and published by Cambridge University Press. This book was released on 2016-04-21 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Containing numerous illustrations and algorithms, this practical guide enlightens the diagnostic process for both common and complex bladder diseases.
Download or read book The Cambridge History of Medicine written by Roy Porter and published by Cambridge University Press. This book was released on 2006-06-05 with total page 11 pages. Available in PDF, EPUB and Kindle. Book excerpt: Against the backdrop of unprecedented concern for the future of health care, 'The Cambridge History of Medicine' surveys the rise of medicine in the West from classical times to the present. Covering both the social and scientific history of medicine, this volume traces the chronology of key developments and events.
Download or read book Lymphedema written by Byung-Boong Lee and published by Springer. This book was released on 2018-01-10 with total page 939 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of this book serves as a central source of theoretical and practical knowledge to optimize the evaluation and treatment of patients with lymphedema. The book covers all aspects of the disease from anatomical and histological features to diagnosis as well as physical/medical and surgical management of the disease. Updated from the first edition to reflect the substantial progress in diagnostics, medical care and surgical intervention for this patient population, this volume has been reorganized to meet today’s practice requirements. It addresses the challenges faced by clinicians in the management of chronic lymphedema enabling them to meet the medical needs of this large patient community. Edited by world leaders in Vascular Medicine and Surgery, this comprehensive volume provides clear, concise background and recommendations in an easy-to-use format. It is a valuable reference tool for clinical practitioners (physicians/nurse practitioners/technicians) who wish to deliver state-of-the-art health care to their patients with lymphatic and venous disorders.
Download or read book Carbon Ion Radiotherapy written by Hirohiko Tsujii and published by Springer Science & Business Media. This book was released on 2013-12-25 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.
Download or read book Tamoxifen written by Philipp Y. Maximov and published by Springer Science & Business Media. This book was released on 2013-07-23 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.
Download or read book Western Diseases written by Norman J. Temple and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sir Richard Doll, FRS, FRCP ICRF Cancer Research Studies Unit Radcliffe Infirmary, Oxford, UK The twentieth century has seen few changes more remarkable than the improvement in health that has occurred nearly everywhere, most spectacularly in the economically developed countries. In these countries improved nutrition, better housing, the control ofinfection, smaller family sizes, and higher standards of education have brought about a situation in which more than 97% of all liveborn children can expect to survive the first half ofthe three score years and ten that formerly was regarded as the allotted span oflife. From then on, however, the position is less satisfactory. Some improvement has occurred; but the proportion of survivors who die prematurely, that is under 70 years of age, varies from 25% to over 50% in men and from 13% to 28% in women, the extremes in both sexes being recorded, respectively, in Japan and Hungary. Most of these deaths under 70 years of age must now be called premature, even in Japan. For most of them are not the result of any inevitable aging process, but instead are the consequences of diseases (or types of trauma) that have lower-often much lower-age-specific incidence rates in many of the least developed countries.
Download or read book OZONE written by Velio Bocci and published by Springer Science & Business Media. This book was released on 2010-10-05 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxygen-Ozone therapy is a complementary approach less known than homeopathy and acupuncture because it has come of age only three decades ago. This book clarifies that, in the often nebulous field of natural medicine, the biological bases of ozone therapy are totally in line with classical biochemistry, physiological and pharmacological knowledge. Ozone is an oxidizing molecule, a sort of super active oxygen, which, by reacting with blood components generates a number of chemical messengers responsible for activating crucial biological functions such as oxygen delivery, immune activation, release of hormones and induction of antioxidant enzymes, which is an exceptional property for correcting the chronic oxidative stress present in atherosclerosis, diabetes and cancer. Moreover, by inducing nitric oxide synthase, ozone therapy may mobilize endogenous stem cells, which will promote regeneration of ischemic tissues. The description of these phenomena offers the first comprehensive picture for understanding how ozone works and why. When properly used as a real drug within therapeutic range, ozone therapy does not only does not procure adverse effects but yields a feeling of wellness. Half the book describes the value of ozone treatment in several diseases, particularly cutanious infection and vascular diseases where ozone really behaves as a “wonder drug”. The book has been written for clinical researchers, physicians and ozone therapists, but also for the layman or the patient interested in this therapy.
Download or read book Essentials of Anatomic Pathology written by Liang Cheng and published by Springer Science & Business Media. This book was released on 2011-03-18 with total page 1867 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the 8 years since the publication of the first edition of Essentials of Anatomic Pathology, great strides have been made in our understanding of diseases and neoplastic processes. Many clinically important new histopathologic entities have been described or more fully defined in virtually every organ. Numerous clinically important diagnostic and prognostic markers have entered routine practice. Genetic testing for the early detection of cancers and the molecular classification of diseases has become increasingly important. This is an age of enlightenment in surgical pathology, and the authors of this new volume have captured this sense of excitement herein. This much praised and widely used reference manual on has been extensively revised and expanded to cover the entire field of anatomic pathology. The Third Edition features the incorporation of full-color images in the text with updates of new diagnostic and prognostic information. New classifications and numerous new entities and histologic variants are fully explored. Useful immunostaining biomarkers and emerging molecular targets and relevant molecular findings that have emerged from recent genomic studies are incorporated in each chapter. Written by internationally recognized authorities, the comprehensive, evidence-based practice information is presented in an outline format that is clear and easy to follow. Up-to-date and richly detailed, Essentials of Anatomic Pathology, Third Edition offers both the pathologist-in-training and the practicing pathologist a concise summary of all the critical information needed to recognize, understand and interpret anatomic pathology.
Download or read book Treatment Plans and Interventions for Depression and Anxiety Disorders written by Robert L. Leahy and published by Guilford Press. This book was released on 2011-10-26 with total page 740 pages. Available in PDF, EPUB and Kindle. Book excerpt: "_This widely used book is packed with indispensable tools for treating the most common clinical problems encountered in outpatient mental health practice. Chapters provide basic information on depression and the six major anxiety disorders; step-by-stepinstructions for evidence-based assessment and intervention; illustrative case examples; and practical guidance for writing reports and dealing with third-party payers. In a convenient large-size format, the book features 125 reproducible client handouts, homework sheets, and therapist forms for assessment and record keeping. The included CD-ROM enables clinicians to rapidly generate individualized treatment plans, print extra copies of the forms, and find information on frequently prescribed medications._New to This Edition*The latest research on each disorder and its treatment.*Innovative techniques that draw on cognitive, behavioral, mindfulness, and acceptance-based approaches.*Two chapters offering expanded descriptions of basic behavioral and cognitive techniques.*47 of the 125 reproducibles are entirely new. __"--Provided by publisher.
