Download or read book Quorum Sensing vs Quorum Quenching A Battle with No End in Sight written by Vipin Chandra Kalia and published by Springer. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS system through natural and synthetic compounds have been presented here. The biotechnological applications of QS inhibitors (QSIs) in diverse areas have also been dealt with. Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs. This book addresses a few questions. Will bacteria develop mechanisms to evade QSIs? Are we watching yet another defeat at the hands of bacteria? Or will we be acting intelligently and survive the onslaughts of this Never Ending battle?
Download or read book Quorum Sensing written by Giuseppina Tommonaro and published by Academic Press. This book was released on 2019-04-08 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists. - Describes Quorum Sensing (QS) mechanisms from their molecular basis, to their clinical applications - Spans several fields in relation to QS, including microbiology, chemistry, biochemistry and ecology - Considers QS as an approach to the discovery of new antibiotics - Looks at QS as a means to understand the microbial world and towards use of bacteria and their products in biotechnological applications - Summarizes key results on QS mechanisms' molecular basis and fields of application
Download or read book Quorum Sensing written by Saurabh Sudha Dhiman and published by . This book was released on 2021 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: New developments in researching quorum sensing Microbial growth affects industries as diverse as agriculture, engineering, and medicine, to name a few. As more precise solutions are needed for modern challenges, researchers must understand the mechanisms of microbial growth. Quorum sensing (QS) is an essential part of microbial growth, and this work contains key areas such as signal molecules; mechanisms of signal transfer, role, and type of signal receptors; quorum quenching; characterization of microbial plasmids in quorum sensing; and novel and underexplored molecules involved in QS, along with therapeutic roles of quorum sensing inhibitors. This volume is perfect for researchers working on microbiology or biotechnology.
Download or read book Bacterial Signaling written by Reinhard Krämer and published by John Wiley & Sons. This book was released on 2009-12-09 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing a comprehensive insight into cellular signaling processes in bacteria with a special focus on biotechnological implications, this is the first book to cover intercellular as well as intracellular signaling and its relevance for biofilm formation, host pathogen interactions, symbiotic relationships, and photo- and chemotaxis. In addition, it deals in detail with principal bacterial signaling mechanisms -- making this a valuable resource for all advanced students in microbiology. Dr. Krämer is a world-renowned expert in intracellular signaling and its implications for biotechnology processes, while Dr. Jung is an expert on intercellular signaling and its relevance for biomedicine and agriculture.
Download or read book Bacterial Biofilms written by Tony Romeo and published by Springer Science & Business Media. This book was released on 2008-02-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.
Download or read book Trends in Quorum Sensing and Quorum Quenching written by V. Ravishankar Rai and published by CRC Press. This book was released on 2020-05-04 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book on Trends in Quorum Sensing and Quorum Quenching: New Perspectives and Applications focuses on the recent advances in the field of quorum sensing in bacteria and the novel strategies developed for quorum sensing inhibition. The topics covered are multidisciplinary and wide-ranging,and includes quorum sensing phenomenon in pathogenic bacteria, food spoilers, and agriculturally relevant bacteria. The applications of quorum sensing inhibitors such as small molecules, bioactives, natural compounds, and quorum quenching enzymes in controlling bacterial infections in clinical settings, agriculture and aquaculture are discussed. The potential use of quorum quenching enzymes for mitigating biofouling is also covered. Special focus is given to exploring quorum sensing inhibitors from microbes and flora inhabiting biodiversity rich regions including tropical rain forests and marine environments. Key features: Covers the fundamental aspects, the progress and challenges in the field of quorum sensing and quorum quenching Reviews quorum sensing in Gram-positive and Gram-negative bacteria of clinical, agricultural, and industrial relevance Discusses the application and future trends of quorum sensing inhibitors from lab to clinical and environmental settings Provides comprehensive coverage on molecular mechanisms in bacterial signaling
Download or read book Implication of Quorum Sensing and Biofilm Formation in Medicine Agriculture and Food Industry written by Pallaval Veera Bramhachari and published by Springer Nature. This book was released on 2019-11-26 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book illustrates the role of quorum sensing in the food industry, agriculture, veterinary sciences, and medicine. It highlights the importance of quorum sensing in regulating diverse cellular functions in microbes, including virulence, pathogenesis, controlled-gene expression systems, and antibiotic resistance. This book also describes the role of quorum sensing in survival behavior and antibiotic resistance in bacteria. Further, it reviews the major role played by quorum sensing in food spoilage, biofilm formation, and food-related pathogenesis. It also explores the methods for the detection and quantification of quorum sensing signals. It also presents antimicrobial and anti-quorum sensing activities of medicinal plants. Finally, the book elucidates a comprehensive yet representative description of basic and applied aspects of quorum sensing inhibitors. This book serves an ideal guide for researchers to understand the implications of quorum sensing in the food industry, medicine, and agriculture.
Download or read book Biotechnological Applications of Quorum Sensing Inhibitors written by Vipin Chandra Kalia and published by Springer. This book was released on 2018-05-30 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the practical applications of quorum sensing inhibitors for both human and plant health. Quorum sensing inhibitors that disrupt microbial biofilms can be employed to treat bacterial infections. The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors. Quorum sensing is the mechanism through which bacteria develop antibiotic resistance. Intended to provide a clearer understanding of the practical applications of quorum sensing inhibitors, the book details how the problem of antibiotic resistance can be countered through the intelligent application of quorum sensing inhibitors.
Download or read book Methods in Actinobacteriology written by Dhanasekaran Dharumadurai and published by Humana. This book was released on 2023-01-02 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details techniques on the study of Isolation, characterization, and exploration of actinobacteria in industrial, food, agricultural, and environmental microbiology. Chapters cover a wide range of basic and advanced techniques associated with research on isolation, characterization and identification of actinobacteria in soil, sediment, estuarine, water, Saltpan, Mangroves, plants, lichens, sea weeds, sea grass, animals-crab, snail, shrimp. Authoritative and cutting-edge, Methods in Actinobacteriology aims to be a useful practical guide to researches to help further their study in this field.
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Download or read book Functional Foods and Biotechnology written by Kalidas Shetty and published by CRC Press. This book was released on 2006-09-28 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Foods and Biotechnology focuses the information from the recently published Food Biotechnology to illuminate the role of biochemical processing in the improvement of functional foods and the increase of nutrient value. Applying scientific concepts, the text explores the design of functional food ingredients, the bio-mobilization of major nutrients, and the use of specific phenolic metabolites in disease prevention. Specialty topics include oxidation and disease, antibodies from eggs, phytochemicals as antimicrobials, and passive immune improvement with pro- and pre-biotics. The text provides key emerging techniques for improving food production and processing, enhancing food safety and quality, and increasing nutritional values a
Download or read book Quorum Sensing and its Biotechnological Applications written by Vipin Chandra Kalia and published by Springer. This book was released on 2018-08-11 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book delves into the biotechnological applications of Quorum sensing (QS)- a peculiar gene-regulatory process of some microorganisms. Quorum Sensing allows a large bacterial population to work together in a coordinated manner to carry out metabolic activities, which individual bacterium cannot. The different chapters describe how, associating bioremediation process with energy generation is an economical proposal, for reducing pollution and managing biowastes. The book discusses how QS can be exploited for biotechnological applications in generating bioproducts, bioenergy, bioremediation, biosensors, health and agricultural activities. It further highlights how QS is becoming an integral part of synthetic biology for genetic circuits for producing: (i) novel products, (ii) biosensors, (iii) bioactive molecules, etc. The book is divided into different sections for a clear understanding of the applicability of QS in, the Environment, Energy, Agriculture and Health sectors.
Download or read book Fundamentals of and Applications Based on Quorum Sensing and Quorum Sensing Interference written by Cristina García-Aljaro and published by Frontiers Media SA. This book was released on 2020-01-23 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: Background Bacteria use quorum sensing (QS) circuits to coordinate various activities (among which biofilm formation and the expression of virulence factors) based on the presence of signaling molecules. Different families of signal molecules have been identified in Gram positive and Gram negative bacteria (e.g. autoinducer peptides and acyl homoserine lactones). Similarly, different quorum sensing antagonists interfering with these system have been found in nature, promoting a new and promising field of research, quorum sensing interference. One of the most intensively studied applications of quorum sensing interference is its use as an alternative or synergycally with antibiotics to fight (antibiotic-resistant) bacterial pathogens. Many studies have been published claiming quorum sensing inhibitory activity of natural and synthetic compounds. However, after decades of research, several questions regarding the suitability of this approach to fight bacterial pathogens remain unanswered, including the risk that pathogens will develop resistance against quorum quenching. Meanwhile, the interest in quorum sensing has increased considerably, and this has broadened the fields where it can find biotechnological, environmental and industrial applications, such as anti biofouling, steering fermentations, bioremediation and wastewater treatment. Goal and scope The goal of this Research Topic is to broaden the knowledge of the phenotypes regulated by quorum sensing and the advances in quorum sensing interference. Deciphering microorganism language and the different phenotypes regulated by microbial signalling systems is a frontier for the development of new tools for the management of microorganisms to fulfil human needs with a broad application in different areas such as medicine, environmental sciences and industry.
Download or read book Biofouling written by Simone Dürr and published by John Wiley & Sons. This book was released on 2009-12-21 with total page 477 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biofouling (the colonisation of an interface by a diverse array of organisms) is almost always a problem where it occurs, as it negatively affects surfaces, the materials that they are made from and the structures that they form, and can even destroy them. This comprehensive book covers in detail in its first section the processes involved in marine , freshwater and medical biofouling including coverage of settlement by larvae and spores, biofouling community processes, epibiosis (biofouling on living organisms) and microbial fouling, including biofilms deleterious to human health. The book's second section, encompassing biofouling processes with industrial implications, includes coverage of biofouling on artificial substrata, paints and coatings technology for the control of marine biofouling, biofouling and antifouling in the maritime industries, such as shipping, offshore oil , and aquaculture, and in power stations and other industries. The impacts of both biofouling and biofouling control and details of current legislation of relevance to biofouling issues are fully covered. The book's final section looks at methods for the measurement of biofouling, and future prospects for biofouling, including in-depth coverage of the changes anticipated in biofouling worldwide due to global climate change, and likely future directions in antifouling research, technology and legislation. Biofouling, which includes contributions from many international experts, is an essential reference for all those working in the antifouling industry including those involved in formulation of antifouling products such as paints and other coatings. Aquatic biologists, ecologists, environmental scientists and lawyers, marine engineers, aquaculture personnel, chemists, and medical researchers will all find much of interest within this book. All universities and research establishments where these subjects are studied and taught should have copies of this important work on their shelves.
Download or read book Microbial Biotechnology Basic Research and Applications written by Joginder Singh and published by Springer Nature. This book was released on 2020-07-07 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial biotechnology is an important area that promotes advanced research into using microbes for value-added products, human nutrition, and the overall wellbeing of society. This book presents the latest information on the use of microbes for sustainable development, and highlights state-of-the-art biotechnological techniques used to harness microbial biotechnological traits on a commercial scale. Gathering contributions from authoritative researchers in the field, it addresses recent advances in microbial biotechnological approaches that offer sustainable options for future generations. Exploring a broad range of microbial products and their uses, the book specifically places emphasis on the application of microorganisms in healthcare, the environment and industry. It also discusses various compound classes derived from microbial metabolites. Pursuing a holistic approach to recent advances in the utilization of various microbes as biotechnological tools, the book also covers traditional uses, and explores emerging strategies to harness their full potential. Accordingly, it offers a valuable resource for researchers and graduate students alike.
Download or read book Implication of Quorum Sensing System in Biofilm Formation and Virulence written by Pallaval Veera Bramhachari and published by Springer. This book was released on 2019-01-28 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book illustrates the importance and significance of Quorum sensing (QS), it’s critical roles in regulating diverse cellular functions in microbes, including bioluminescence, virulence, pathogenesis, gene expression, biofilm formation and antibiotic resistance. Microbes can coordinate population behavior with small molecules called autoinducers (AHL) which serves as a signal of cellular population density, triggering new patterns of gene expression for mounting virulence and pathogenesis. Therefore, these microbes have the competence to coordinate and regulate explicit sets of genes by sensing and communicating amongst themselves utilizing variety of signals. This book descry emphasizes on how bacteria can coordinate an activity and synchronize their response to external signals and regulate gene expression. The chapters of the book provide the recent advancements on various functional aspects of QS systems in different gram positive and gram negative organisms. Finally, the book also elucidates a comprehensive yet a representative description of a large number of challenges associated with quorum sensing signal molecules viz. virulence, pathogenesis, antibiotic synthesis, biosurfactants production, persister cells, cell signaling and biofilms, intra and inter-species communications, host-pathogen interactions, social interactions & swarming migration in biofilms.
Download or read book Fungal Siderophores written by Kalyani Dhusia and published by Springer Nature. This book was released on 2021-02-08 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past few decades, it has been realized through research that fungal siderophores epitomize the uptake of iron as well as other essential elements like zinc, magnesium, copper, nickel and arsenic. Understanding the chemical structures of different fungal siderophores and the membrane receptors involved in uptake of mineral ions has opened new areas for research. In this edited volume, recent research is presented on fungal siderophores in one comprehensive volume to provide researchers a strong base for future research. Siderophores are the low molecular weight, high affinity iron-chelating compounds produced by bacteria and fungi. They are responsible for transporting iron across the cell membrane. Fungi produce a range of hydroxamate siderophores involved in the uptake of essential elements in almost all microorganisms and plants. In recent years, siderophores have been used in molecular imaging applications to visualize and understand cellular functions, which thus provide an opportunity to identify new drug targets. Therefore, knowledge of fungal siderophores has become vital in current research. Siderophores have received much attention in recent years because of their potential roles and applications in various research areas. Their significance in these applications is because siderophores have the ability to bind a variety of metals in addition to iron, and they have a wide range of chemical structures and specific properties. For instance, siderophores function as biocontrols, biosensors, and bioremediation and chelation agents, in addition to their important role in weathering soil minerals and enhancing plant growth. This book focuses on siderophores with the following significant points. It discusses leading, state-of-the-art research in all possible areas on fungal siderophores. The contributors are well-known and recognized authorities in the field of fungal siderophores. It discusses a projection of practical applications of fungal siderophores in various domains. This is the first book exclusively on fungal siderophores. In this comprehensive, edited volume, we show leading research on fungal siderophores and provide the most recent knowledge of researchers' work on siderophores. This book presents in-depth knowledge on siderophores to researchers working in areas of health sciences, microbiology, plant sciences, biotechnology, and bioinformatics.
