Download or read book Bioprocessing Piping and Equipment Design written by William M. (Bill) Huitt and published by John Wiley & Sons. This book was released on 2016-09-23 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive and authoritative reference guide to the ASME Bioprocessing Piping and Equipment (BPE) standard This is a companion guide to the ASME Bioprocessing Piping and Equipment (BPE) Standard and explains what lies behind many of the requirements and recommendations within that industry standard. Following an introductory narrative to the Standard's early history, industry related codes and standards are explained; the design and engineering aspects cover construction materials, both metallic and nonmetallic; then components, fabrication, assembly and installation of piping systems are explored. Examination, Inspection and Testing then precede the ASME BPE certification process, concluding with a discussion on system design. The author draws on many years' experience and insights from first-hand involvement in the field of industrial piping design, engineering, construction, and management, which includes the bioprocessing industry. The reader will learn why dimensions and tolerances, process instrumentation, and material selection play such an integral part in the manufacture of components and instrumentation. This easy to understand and navigate guide will assist engineers (design, piping, chemical, etc.) who need to understand the basis for much of the Standard’s content, as do the contractors and inspectors who have to meet and validate compliance with the BPE Standard.
Download or read book Bioprocessing Piping and Equipment Design written by William M. (Bill) Huitt and published by John Wiley & Sons. This book was released on 2016-09-23 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: The only comprehensive and authoritative reference guide to the ASME Bioprocessing Piping and Equipment (BPE) standard This is a companion guide to the ASME Bioprocessing Piping and Equipment (BPE) Standard and explains what lies behind many of the requirements and recommendations within that industry standard. Following an introductory narrative to the Standard's early history, industry related codes and standards are explained; the design and engineering aspects cover construction materials, both metallic and nonmetallic; then components, fabrication, assembly and installation of piping systems are explored. Examination, Inspection and Testing then precede the ASME BPE certification process, concluding with a discussion on system design. The author draws on many years' experience and insights from first-hand involvement in the field of industrial piping design, engineering, construction, and management, which includes the bioprocessing industry. The reader will learn why dimensions and tolerances, process instrumentation, and material selection play such an integral part in the manufacture of components and instrumentation. This easy to understand and navigate guide will assist engineers (design, piping, chemical, etc.) who need to understand the basis for much of the Standard’s content, as do the contractors and inspectors who have to meet and validate compliance with the BPE Standard.
Download or read book Bioprocess Engineering Principles written by Pauline M. Doran and published by Elsevier. This book was released on 1995-04-03 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists.This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems.* * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists* Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems* Comprehensive, single-authored* 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems* 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors* Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading* Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used* Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.
Download or read book Bioprocess Engineering written by Bjorn K. Lydersen and published by John Wiley & Sons. This book was released on 1994-04-18 with total page 837 pages. Available in PDF, EPUB and Kindle. Book excerpt: Divided into four sections, the first and third reflect the fact that there are two types of equipment required in the plant--one in which the actual product is synthesized or processed such as the fermentor, centrifuge and chromatographic columns; and the other that supplies support for the facility or process including air conditioning, water and waste systems. Part two describes such components as pumps, filters and valves not limited to a certain type of equipment. Lastly, it covers planning and designing the entire facility along with requirements for containment and validation of the process.
Download or read book Bioprocessing Piping and Equipment Design written by William Huitt and published by . This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Serving as a companion guide to the ASME Bioprocessing Piping and Equipment (BPE) Standard and explaining what lies behind many of the requirements and recommendations within that industry standard, this book shows readers why dimensions and tolerances, process instrumentation, and material selection play such an integral part in the manufacture of components and instrumentation. --
Download or read book Biopharmaceutical Processing written by Gunter Jagschies and published by Elsevier. This book was released on 2018-01-18 with total page 1310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry. The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related to downstream purification and upstream processing fields. Economic considerations are included throughout, with recommendations for lowering costs and improving efficiencies. Designed for quick reference and easy accessibility of facts, calculations and guidelines, this book is an essential tool for industrial scientists and managers in the biopharmaceutical industry. - Offers a comprehensive, go-to reference for daily work decisions - Covers both upstream and downstream processes - Includes case studies that emphasize financial outcomes - Presents summaries, decision grids, graphs and overviews for quick reference
Download or read book Bioseparations Science and Engineering written by Roger G. Harrison and published by Oxford University Press. This book was released on 2015-01-27 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed for undergraduates, graduate students, and industry practitioners, Bioseparations Science and Engineering fills a critical need in the field of bioseparations. Current, comprehensive, and concise, it covers bioseparations unit operations in unprecedented depth. In each of the chapters, the authors use a consistent method of explaining unit operations, starting with a qualitative description noting the significance and general application of the unit operation. They then illustrate the scientific application of the operation, develop the required mathematical theory, and finally, describe the applications of the theory in engineering practice, with an emphasis on design and scaleup. Unique to this text is a chapter dedicated to bioseparations process design and economics, in which a process simular, SuperPro Designer® is used to analyze and evaluate the production of three important biological products. New to this second edition are updated discussions of moment analysis, computer simulation, membrane chromatography, and evaporation, among others, as well as revised problem sets. Unique features include basic information about bioproducts and engineering analysis and a chapter with bioseparations laboratory exercises. Bioseparations Science and Engineering is ideal for students and professionals working in or studying bioseparations, and is the premier text in the field.
Download or read book Cell Culture Bioprocess Engineering Second Edition written by Wei-Shou Hu and published by CRC Press. This book was released on 2020-03-06 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the culmination of three decades of accumulated experience in teaching biotechnology professionals. It distills the fundamental principles and essential knowledge of cell culture processes from across many different disciplines and presents them in a series of easy-to-follow, comprehensive chapters. Practicality, including technological advances and best practices, is emphasized. This second edition consists of major updates to all relevant topics contained within this work. The previous edition has been successfully used in training courses on cell culture bioprocessing over the past seven years. The format of the book is well-suited to fast-paced learning, such as is found in the intensive short course, since the key take-home messages are prominently highlighted in panels. The book is also well-suited to act as a reference guide for experienced industrial practitioners of mammalian cell cultivation for the production of biologics.
Download or read book Flow Induced Vibration Handbook for Nuclear and Process Equipment written by Michel J. Pettigrew and published by John Wiley & Sons. This book was released on 2021-10-29 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the mechanisms governing flow-induced vibrations and helps engineers prevent fatigue and fretting-wear damage at the design stage Fatigue or fretting-wear damage in process and plant equipment caused by flow-induced vibration can lead to operational disruptions, lost production, and expensive repairs. Mechanical engineers can help prevent or mitigate these problems during the design phase of high capital cost plants such as nuclear power stations and petroleum refineries by performing thorough flow-induced vibration analysis. Accordingly, it is critical for mechanical engineers to have a firm understanding of the dynamic parameters and the vibration excitation mechanisms that govern flow-induced vibration. Flow-Induced Vibration Handbook for Nuclear and Process Equipment provides the knowledge required to prevent failures due to flow-induced vibration at the design stage. The product of more than 40 years of research and development at the Canadian Nuclear Laboratories, this authoritative reference covers all relevant aspects of flow-induced vibration technology, including vibration failures, flow velocity analysis, vibration excitation mechanisms, fluidelastic instability, periodic wake shedding, acoustic resonance, random turbulence, damping mechanisms, and fretting-wear predictions. Each in-depth chapter contains the latest available lab data, a parametric analysis, design guidelines, sample calculations, and a brief review of modelling and theoretical considerations. Written by a group of leading experts in the field, this comprehensive single-volume resource: Helps readers understand and apply techniques for preventing fatigue and fretting-wear damage due to flow-induced vibration at the design stage Covers components including nuclear reactor internals, nuclear fuels, piping systems, and various types of heat exchangers Features examples of vibration-related failures caused by fatigue or fretting-wear in nuclear and process equipment Includes a detailed overview of state-of-the-art flow-induced vibration technology with an emphasis on two-phase flow-induced vibration Covering all relevant aspects of flow-induced vibration technology, Flow-Induced Vibration Handbook for Nuclear and Process Equipment is required reading for professional mechanical engineers and researchers working in the nuclear, petrochemical, aerospace, and process industries, as well as graduate students in mechanical engineering courses on flow-induced vibration.
Download or read book Companion Guide to the ASME Boiler Pressure Vessel Code written by K. R. Rao and published by American Society of Mechanical Engineers. This book was released on 2006 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is Volume 1 of the fully revised second edition. Organized to provide the technical professional with ready access to practical solutions, this revised, three-volume, 2,100-page second edition brings to life essential ASME Codes with authoritative commentary, examples, explanatory text, tables, graphics, references, and annotated bibliographic notes. This new edition has been fully updated to the current 2004 Code, except where specifically noted in the text. Gaining insights from the 78 contributors with professional expertise in the full range of pressure vessel and piping technologies, you find answers to your questions concerning the twelve sections of the ASME Boiler and Pressure Vessel Code, as well as the B31.1 and B31.3 Piping Codes. In addition, you find useful examinations of special topics including rules for accreditation and certification; perspective on cyclic, impact, and dynamic loads; functionality and operability criteria; fluids; pipe vibration; stress intensification factors, stress indices, and flexibility factors; code design and evaluation for cyclic loading; and bolted-flange joints and connections.
Download or read book Chemical and Bioprocess Engineering written by Ricardo Simpson and published by Springer Science & Business Media. This book was released on 2013-12-04 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this textbook is to provide first-year engineering students with a firm grounding in the fundamentals of chemical and bioprocess engineering. However, instead of being a general overview of the two topics, Fundamentals of Chemical and Bioprocess Engineering will identify and focus on specific areas in which attaining a solid competency is desired. This strategy is the direct result of studies showing that broad-based courses at the freshman level often leave students grappling with a lot of material, which results in a low rate of retention. Specifically, strong emphasis will be placed on the topic of material balances, with the intent that students exiting a course based upon this textbook will be significantly higher on Bloom’s Taxonomy (knowledge, comprehension, application, analysis and synthesis, evaluation, creation) relating to material balances. In addition, this book also provides students with a highly developed ability to analyze problems from the material balances perspective, which leaves them with important skills for the future. The textbook consists of numerous exercises and their solutions. Problems are classified by their level of difficulty. Each chapter has references and selected web pages to vividly illustrate each example. In addition, to engage students and increase their comprehension and rate of retention, many examples involve real-world situations.
Download or read book Metrology and Instrumentation written by Samir Mekid and published by John Wiley & Sons. This book was released on 2021-12-02 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metrology and Instrumentation: Practical Applications for Engineering and Manufacturing provides students and professionals with an accessible foundation in the metrology techniques, instruments, and governing standards used in mechanical engineering and manufacturing. The book opens with an overview of metrology units and scale, then moves on to explain topics such as sources of error, calibration systems, uncertainty, and dimensional, mechanical, and thermodynamic measurement systems. A chapter on tolerance stack-ups covers GD&T, ASME Y14.5-2018, and the ISO standard for general tolerances, while a chapter on digital measurements connects metrology to newer, Industry 4.0 applications.
Download or read book Pressure Oscillation in Biomedical Diagnostics and Therapy written by Ahmed Al-Jumaily and published by John Wiley & Sons. This book was released on 2022-10-04 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complete and comprehensive reference on the principles of diagnostic and therapeutic techniques using pressure oscillation Pressure Oscillation in Biomedical Diagnostics and Therapy presents key findings in imaging, diagnostics, and therapies using high and low frequency pressure waves in a concise and easy-to-understand way, focusing primarily on the cardiovascular and pulmonary systems that utilize acoustics (mechanical wave motion). The work provides basic background in relevant acoustic theory as well as specific technical information associated with modern medical applications. Low frequency acoustics (pressure oscillation) and some aspects of ultrasound (radiation force) are also reviewed. The principles in the work can be extended to include other areas relating to materials and metal diagnostics. To allow for maximum reader comprehension regardless of current expertise on the subject, each chapter includes a brief history, current developments, and practical applications of the topic covered within. Furthermore, all chapters are based on engineering and physiological principles to deliver practical technologies. Sample topics covered in the work include: Fundamental principles of pressure oscillation (PO), discussing the basic principles of pressure oscillation and how they can be formulated into mathematical equations PO in imaging techniques, discussing the basic principles of converting pressure oscillation to a tool in biomedical imaging Lung mechanics, discussing how each part of the lung is associated with various diseases and how PO can target these parts Asthma, discussing the basic concepts of asthma, the importance of airway smooth muscle (ASM), and dynamic behavior of ASM Pressure Oscillation in Biomedical Diagnostics and Therapy links pressure oscillation (PO) and biomedical diagnostics and therapy for scholars and practitioners. It is an essential resource for all professionals who wish to be on the cutting edge of treating lung diseases such as obstructive sleep apnea, asthma, and respiratory distress syndrome.
Download or read book Mixed flow Pumps written by Wei Li and published by John Wiley & Sons. This book was released on 2024-06-05 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to improve and optimize the design and operation of mixed-flow pumps Mixed-flow pumps have a huge range of applications in agriculture, hydroelectric power, and other industries that incorporate fluid transport. They are centrifugal pumps incorporating the characteristics of both axial and radial pumps to increase the flow rate and discharge pressure. Though essential in a variety of industries, they pose serious challenges to numerical simulation methods, challenges which are starting to be met by the application of computational fluid dynamics using high-performance computing. Mixed-flow Pumps introduces engineers and researchers to this subject and its important applications. Incorporating all major varieties of mixed-flow pumps used in industrial applications, it employs methods from advanced computational fluid dynamics and high-precision flow field experimentation to characterize and analyze these crucial technologies. Moving from the fundamentals of the technology to its most advanced applications, it's an essential resource for engineers and industry practitioners looking to develop their understanding of fluid transport. Mixed-flow Pumps readers will also find: Detailed information on how to design and optimize mixed-flow pumps to meet the increasingly stringent industry demands Detailed information on energy performance tests and experiments, methods for data analysis, entropy production theory, CFD solutions using Reynolds-Averaged Navier-Stokes (RANS) equations, and many more An authoritative team with immense global experience in flow pumps and broader industrial experience Mixed-flow Pumps is a useful reference for mixed-flow pump design by academic researchers, including graduate students, industry practitioners, and test engineers.
Download or read book Fabrication of Metallic Pressure Vessels written by Owen R. Greulich and published by John Wiley & Sons. This book was released on 2021-12-09 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fabrication of Metallic Pressure Vessels A comprehensive guide to processes and topics in pressure vessel fabrication Fabrication of Metallic Pressure Vessels delivers comprehensive coverage of the various processes used in the fabrication of process equipment. The authors, both accomplished engineers, offer readers a broad understanding of the steps and processes required to fabricate pressure vessels, including cutting, forming, welding, machining, and testing, as well as suggestions on controlling costs. Each chapter provides a complete description of a specific fabrication process and details its characteristics and requirements. Alongside the accessible and practical text, you’ll find equations, charts, copious illustrations, and other study aids designed to assist the reader in the real-world implementation of the concepts discussed within the book. You’ll find numerous appendices that include weld symbols, volume and area equations, pipe and tube dimensions, weld deposition rates, lifting shackle data, and more. In addition to detailed discussions of cutting, machining, welding, and post-weld heat treatments, readers will also benefit from the inclusion of: A thorough introduction to construction materials, including both ferrous and nonferrous alloys An exploration of layout, including projection and triangulation, material thickness and bending allowance, angles and channels, and marking conventions A treatment of material forming, including bending versus three-dimensional forming, plastic theory, forming limits, brake forming, roll forming, and tolerances Practical discussions of fabrication, including weld preparation, forming, vessel fit up and assembly, correction of distortion, and transportation of vessels Perfect for new and established engineers, designers, and procurement personnel working with process equipment or in the fabrication field, Fabrication of Metallic Pressure Vessels will also earn a place in the libraries of students in engineering programs seeking a one-stop resource for the fabrication of pressure vessels.
Download or read book Perry s Chemical Engineers Handbook 9th Edition written by Don W. Green and published by McGraw Hill Professional. This book was released on 2018-07-13 with total page 2274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-Date Coverage of All Chemical Engineering Topics―from the Fundamentals to the State of the Art Now in its 85th Anniversary Edition, this industry-standard resource has equipped generations of engineers and chemists with vital information, data, and insights. Thoroughly revised to reflect the latest technological advances and processes, Perry's Chemical Engineers' Handbook, Ninth Edition, provides unsurpassed coverage of every aspect of chemical engineering. You will get comprehensive details on chemical processes, reactor modeling, biological processes, biochemical and membrane separation, process and chemical plant safety, and much more. This fully updated edition covers: Unit Conversion Factors and Symbols • Physical and Chemical Data including Prediction and Correlation of Physical Properties • Mathematics including Differential and Integral Calculus, Statistics , Optimization • Thermodynamics • Heat and Mass Transfer • Fluid and Particle Dynamics *Reaction Kinetics • Process Control and Instrumentation• Process Economics • Transport and Storage of Fluids • Heat Transfer Operations and Equipment • Psychrometry, Evaporative Cooling, and Solids Drying • Distillation • Gas Absorption and Gas-Liquid System Design • Liquid-Liquid Extraction Operations and Equipment • Adsorption and Ion Exchange • Gas-Solid Operations and Equipment • Liquid-Solid Operations and Equipment • Solid-Solid Operations and Equipment •Chemical Reactors • Bio-based Reactions and Processing • Waste Management including Air ,Wastewater and Solid Waste Management* Process Safety including Inherently Safer Design • Energy Resources, Conversion and Utilization* Materials of Construction
Download or read book Engineering Practice with Oilfield and Drilling Applications written by Donald W. Dareing and published by John Wiley & Sons. This book was released on 2022-01-20 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains how to apply time-tested engineering design methods when developing equipment and systems for oil industry and drilling applications Although specific requirements and considerations must be incorporated into an engineering design for petroleum drilling and production, the approach for developing a successful solution is the same across many engineering disciplines. Engineering Practice with Oilfield and Drilling Applications helps readers understand the engineering design process while demonstrating how basic engineering tools can be applied to meet the needs of the oil and petroleum industry. Divided into three parts, the book opens with an overview of best practices for engineering design and problem solving, followed by a summary of specific mechanical design requirements for different modes of power generation, transmission, and consumption. The book concludes with explanations of various analytical tools of design and their application in vibration analysis, fluid mechanics, and drilling systems. Throughout the book, clearly written chapters present traditional tools of engineering mechanics, various mathematical models and methods of solution, key references and background information, and more. Featuring hundreds of figures and a wealth of real-word examples from the petroleum industry, this practical reference: Presents a systematic process for developing an engineering design Illustrates the application of engineering tools during all stages of design Discusses key specifications and considerations for pressure vessels and drilling rigs Explains concept evaluation, visualization of a system and its subsystems, implementing feedback from test results, finalizing a design, and presenting manufacturing drawings Drawn from the author's decades of academic and industrial experience, Engineering Practice with Oilfield and Drilling Applications is the perfect textbook for undergraduate and graduate students in Engineering programs, as well as a highly useful reference for mechanical engineers new to the petroleum industry.
