Download or read book Biologics in Inflammatory Bowel Disease written by Scott Plevy Associate Professor of Medicine Division of Gastroenterology and published by Oxford University Press, USA. This book was released on 2010 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt: SERIES OVERVIEW: The Oxford American Pocket Notes are a series of ultra-concise, small-format books for healthcare professionals on topics related to the diagnosis, treatment and management of various medical conditions. Each title typically features an outline of key points, guidelines and tools such as patient assessments and treatment algorithms, for a specific area of medical diagnosis and/or management. Highly practical in format, content and style, the Pocket Notes serve as a quick, easily accessible point-of-care reference for busy practitioners. In effect, they are miniature versions of the Oxford American Medical Library and Oxford American Handbooks in Medicine, capturing the key essentials needed for appropriate assessment and treatment. Inflammatory bowel disease (IBD) is a gastrointestinal condition which causes inflammation of the lining of the digestive tract. This disease affects an estimated one million Americans, usually in the forms of ulcerative colitis (UC) and Crohn's disease (CD). These two diseases have similar symptoms and are often confused for one another. Crohn's disease can occur anywhere in the digestive tract, often spreading deep into the layers of affected tissues, but ulcerative colitis usually affects only the innermost lining (mucosa) of the large intestine and rectum. IBD patients suffer from severe diarrhea and abdominal pain, and may experience other complications, such as arthritis and kidney stones, that affect the body beyond the intestinal tract. The Oxford American Pocket Notes: Biologics in Inflammatory Bowel Disease is a practical guide to the safe administration of biological agents to treat inflammatory gastrointestinal illnesses. This ultra-concise and practical volume focuses on tumor necrosis factor (TNF) blocking therapy (TNF blocker), an important new class of biologic therapy indicated for the treatment of several rheumatic and other auto-immune disorders, including Crohn's disease and ulcerative colitis. This uniquely compact and affordable book features evidence-based discussion and guidelines on the mechanism of action, dosing, administration and safety considerations for the biologic agents approved to treat CD and UC, thus providing practicing physicians with easily accessible tools and insights on the use of these drugs in a daily practice setting. Culled from the pages of Handbook of Biological Therapy, this portable guide is a valuable resource for gastroenterologists, primary care physicians and other healthcare providers involved in the management of these chronic but treatable diseases.
Download or read book Biologics in Inflammatory Bowel Disease An issue of Gastroenterology Clinics of North America written by Edward V. Loftus Jr and published by Elsevier Health Sciences. This book was released on 2014-09-28 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: By the time this issue of Gastroenterology Clinics of North America is released, it will have been 16 years since infliximab was approved by the US Food and Drug Administration for the treatment of moderate to severe Crohn disease. Not only have we come a long way in understanding the efficacy and safety of infliximab, we are beginning to understand how and when to use the drug. Furthermore, as of this writing, we have five other biologic agents approved for either Crohn disease or ulcerative colitis, and there are many more molecules currently in drug development for these indications. In this issue,the Editors have assembled a collection of experts to provide the most cutting-edge information on the status of biologic therapy for inflammatory bowel disease.
Download or read book Treatment of Inflammatory Bowel Disease with Biologics written by Adam S. Cheifetz and published by Springer. This book was released on 2017-11-09 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise yet comprehensive overview of the use of biologics for the treatment of Crohn’s disease and ulcerative colitis. The volume details how best to utilize these medications in order to optimize their efficacy and safety, as well as how to understand, recognize, and treat complications that may arise from using biologics to treat IBD. The text also focuses on new data, novel biologics, and biosimilars of this rapidly expanding field. Written by experts in the field, Treatment of Inflammatory Bowel Disease with Biologics is a valuable resource for gastroenterologists, allied health professionals, fellows, and trainees who treat patients with inflammatory bowel disease.
Download or read book Biologics in Inflammatory Bowel Disease written by Scott Plevy and published by OUP USA. This book was released on 2012-10 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biologics in Inflammatory Bowel Disease is a practical guide to the safe administration of biological agents to treat inflammatory gastrointestinal illnesses. This ultraconcise and practical volume focuses on tumour necrosis factor (TNF) blocking therapy (TNF blocker), and important new class of biologic therapy indicated for the treatment of several rheumatic and other auto-immune disorders, including Crohn's disease and ulcerative colitis.
Download or read book Harrison s Principles of Internal Medicine written by Tinsley Randolph Harrison and published by McGraw-Hill Companies. This book was released on 1998 with total page 2569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Classic text for practitioners, residents, and students.
Download or read book Advances in Inflammatory Bowel Diseases written by P. Rutgeerts and published by Springer Science & Business Media. This book was released on 1998-12-31 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ulcerative colitis and Crohn's disease remain a great therapeutic challenge to the medical community. In recent years knowledge about the pathogenesis of these diseases has progressed rapidly but the cause of the diseases remains completely unknown. It has become clear that dysregulation of the mucosal immune system is the basis for the chronic evolution of the diseases in a genetically susceptible population. Exciting new therapeutic approaches have been attempted in the last couple of years and cytokine and anti-cytokine treatments in particular seem very promising, especially in intractable disease. The format of the Falk Symposium 106 on `Advances in Inflammatory Bowel Diseases', held in Brussels, Belgium, June 18-20, 1998, was somewhat innovative as each session attempted to link the new insights into pathogenetic mechanisms with new therapeutic approaches, resulting in optimal information transfer. The classic therapeutic schemes were updated with a special focus on step-wise build-up of therapy.
Download or read book The Role of Biologic Therapy in Inflammatory Bowel Disease written by Gary R. Lichtenstein and published by . This book was released on 2006 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dr. Gary Lichtenstein, one of the top experts on IBD, has assimilated an international group of experts who will explore the use of infliximab and other similar biologics for use in patients with Ulcerative Colitis, luminal Crohn's Disease and fistulizing Crohn's disease. The perceived mechanisms of action, and adverse events will be reviewed. Similar agents under investigation will be reviewed. The review will focus on clinically relevant issues for the practicing clinician and also focus on important laboratory based information that the investigator needs to know. Areas of focus include regulatory issues with biologics in IBD, management of infusion reactions in patients receiving infliximab, the economics of use of biologics, recognizing and preventing adverse events with use of infliximab and other biologics, A review of putative targets for novel biologics and also a review of current agents under investigation will also be included. This guide for the experienced researcher and for the novice who has yet to use biologic therapy to treat IBD will be a state of the art overview of the current literature for infliximab and other biologics in IBD. Gastroenterologists, surgeons, family physicians, gynecologists, internists, medical students, nurses and all other health care deliverers who are caring for patients with Inflammatory bowel disease must have this issue because it focuses is on clinically relevant topics, patient management issues; laboratory-based investigations will be touched upon with a translational focus. Key Words: Biologics, Infliximab, monoclonal antibody, Crohn's Disease, Fistulae, Ulcerative Colitis, Refractory Crohn's Disease, novel therapy, economics, fistulae, luminal Crohn's disease, infusion reactions.
Download or read book GI Surgery Annual written by Peush Sahni and published by Springer. This book was released on 2019-03-29 with total page 269 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 25th volume of this highly successful series covers a range of interesting topics, including biological therapy in inflammatory bowel disease, recent surgical approaches in rectal cancer, tumor markers in HPB and GI malignancies, bridging therapy for hepatocellular carcinoma, adjuncts to liver resection, IgG-related HPB diseases, ERCP-induced perforations and superior mesenteric artery syndrome. As in the previous volumes, the chapter on advances in GI surgery reviews the important new developments in the field. The GI Surgery Annual 25th Volume provides up-to-date information on current hot topics.
Download or read book Pediatric Inflammatory Bowel Disease written by Petar Mamula and published by Springer Science & Business Media. This book was released on 2012-12-14 with total page 573 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pediatric Inflammatory Bowel Disease, Second Edition provides an essential reference with an emphasis on the unique pediatric issues of IBD. Chapters focus on complications of IBD specific to children and adolescents. Treatment recommendations are based on the latest clinical research available. The textbook also presents sections dedicated to the aspects of participation in clinical research unique to children and adolescents and the complicated yet vital process of successfully transitioning a patient from a pediatric to adult specialist. Controversies in pediatric IBD care such as the off-label use of medications are also covered. The format incorporates multiple tables, graphs, and figures to improve readability and make for an efficient reference for clinicians to use. Thoroughly revised and updated from the first edition, the volumes includes new therapies that are currently being used or tested for treatment of IBD, important areas regarding incidence and prevalence, immunization and response to vaccine administration as well as advancements in our understanding of growth and development with particular to the use of growth hormone therapy. Other new areas covered include important topics of complementary and alternative medicine use in IBD, immunization, and liver disease in IBD. Pediatric Inflammatory Bowel Disease, Second Edition is a valuable resource for pediatric gastroenterologists as well as adult gastroenterologists.
Download or read book Biological Therapy for Inflammatory Bowel Disease written by Raquel Franco Leal and published by BoD – Books on Demand. This book was released on 2020-03-11 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of inflammatory bowel disease (IBD) has posed a major challenge since its appearance. Biomedical researchers, physicians, gastroenterologists, and surgeons have struggled to improve the quality of life of their patients and have sought, above all else, to keep the disease under remission for as long as possible. Blockers for tumoral necrosis factor alpha (TNF-alpha) were the first biological drugs to be discovered and for this reason they played a crucial role in the subsequent evolution of IBD treatment. The aim of this book is to provide an overview of such drugs and the latest developments in IBD immunopathology. Our contributors discuss the main indications, efficacy, and possible side effects of the different types of drugs available today for IBD treatment.
Download or read book Crohn s Disease and Ulcerative Colitis written by Daniel C. Baumgart and published by Springer. This book was released on 2017-03-01 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders.
Download or read book Biomarkers in Inflammatory Bowel Diseases written by Nik Sheng Ding and published by Springer. This book was released on 2019-05-13 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and complete overview of biomarkers in clinical practice for inflammatory bowel disease (IBD) bringing together the literature in a clear and concise manner. The book bridges the gap between growing knowledge at the bench and current and future applications of biomarkers in clinical practice. The central structure of the book focuses on prognostic and predictive biomarkers in IBD with an emphasis on the fields of research and scientific techniques (genomics, proteomics and metabonomics) that have led to biomarker discovery and places these biomarkers within a clinical context to help understand their utility in clinical practice. This book will be of use to clinicians who have an interest in using biomarkers in clinical practice as well as clinician researchers and scientists involved in the biomarker research pipeline. The author team comprises experts from around the world in order to bring together the literature in an effort to inform clinicians and researchers about the current state-of-the art in biomarker discovery. It is intended to assist future research efforts and indicate how biomarkers might be best applied to clinical practice both at present and in the future.
Download or read book Adverse Reactions to Biologics written by L. Puig and published by Karger Medical and Scientific Publishers. This book was released on 2017-11-07 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: In many areas of medicine physicians still face the great challenge of finding therapies that will meet the patients’ needs. In dermatology the challenge has arisen on multiple fronts through advances in the understanding of the immunopathogenesis of many inflammatory and malignant cutaneous disorders. Breakthroughs, combined with significant developments in targeted immunotherapy, have resulted in improved outcomes as these newer therapies are being used for both approved indications and as off-label therapies for various chronic inflammatory skin disorders and many forms of skin cancer. In the expectation that by truly understanding the safety profile of these targeted therapies patients’ outcomes will be significantly improved, this book offers insights into topics such as adverse reactions, infectious complications and the perioperative use of biologics in psoriasis, immunogenicity of biologic therapies, paradoxical reactions, safety of biologics used to treat autoimmune bullous diseases and primary cutaneous lymphomas, adverse reactions and skin manifestations of therapies targeting melanoma and non-melanoma skin cancer and other neoplastic diseases. Eminent researchers with extensive clinical experience have contributed to this publication, providing an in-depth overview of the latest knowledge in this field.
Download or read book Therapeutic Immunosuppression written by Angus W. Thomson and published by Springer Science & Business Media. This book was released on 2001 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has broad applications in clinical medicine, ranging from prevention and treatment of organ and bone marrow transplant rejection, management of various autoimmune disorders (for example, rheumatoid arthritis), skin disease and asthma. Whereas traditionally only a small repertoire of immunosuppressive agents was available for clinical use, recent discoveries have significantly increased the number of approved agents, resulting in numerous trials to further evaluate their potential. There is also considerable interest in the potential of cell-based therapies (particularly hematopoietic stem and dendritic cell therapy) of allo- and autoimmunity. Important recent advances in the immunotherapy of allergic diseases are also covered in this book. This volume is intended both for practising physicians and surgeons and for biomedical scientists at the graduate/postdoctoral levels, and is designed to provide the theory behind these various approaches to immunosuppression, and to provide state-of-the-art reviews of current developments in each area.
Download or read book Biologic Therapy for Inflammatory Bowel Diseases written by Daniel C. Baumgart and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Evidence Based Medicine Toolkit written by Carl Heneghan and published by John Wiley & Sons. This book was released on 2013-05-06 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This bestselling pocket guide to the skills of evidence-basedmedicine succeeds in demystifying the terminology and processes ina handy and easy-to-follow format, all within the space of 100pages. With an improved layout, this second edition ofEvidence-based Medicine Toolkit offers more up-to-dateguidance as well as new sections on important areas ofresearch. New features of this second edition include: A box for each major database showing how to search theevidence, and highlighting the differences between them Flow charts for different study types New critical appraisal sections on qualitative research andeconomic evaluation Expanded list of EBM resources on the net. With these added features to make the job easier, the newToolkit is now an even better companion for all health careprofessionals using evidence-based methodology in their researchand practice.
Download or read book Inflammatory Bowel Disease written by Ramona Rajapakse and published by Springer Nature. This book was released on 2021-09-23 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book uses new thinking on precision medicine and the interplay of genetic factors, the microbiome, and external triggers to build on the core concepts of inflammatory bowel disease. It outlines the latest findings in targeting therapies to the individual patient with Crohn’s and colitis, management of chronic infections in the setting of immunomodulators and biologics, non-surgical therapy of dysplasia in colitis patients, and redefining and structuring the problematic pouch. In addition, this book features useful chapters dedicated to the economic aspects of IBD in an increasingly constrained healthcare system, as well as the patient experience and the role of subspecialist telemedicine care. Written by specialists and thought leaders in the field, Inflammatory Bowel Disease: Pathogenesis, Diagnosis and Management provides a concise but highly relevant account of the latest thinking and concepts in IBD.
