Download or read book Biologic Applications of Radiotracers written by Howard J. Glenn and published by CRC Press. This book was released on 2019-08-14 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1982: This present volume presents an excellent amount of animal Models in radiotracer investigations, describes the animal radiopharmacology laboratory, and discusses radiotracer distribution differences between species.
Download or read book Biologic Applications of Radiotracers written by Howard J. Glenn and published by . This book was released on 1982 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biologic Applications of Radiotracers written by Howard J. Glenn and published by CRC Press. This book was released on 2019-08-14 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1982: This present volume presents an excellent amount of animal Models in radiotracer investigations, describes the animal radiopharmacology laboratory, and discusses radiotracer distribution differences between species.
Download or read book Biologic Applications of Radiotracers written by HJ Glenn (Ed) and published by . This book was released on 1982 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Radiotracers for Medical Applications written by Garimella V. S. Rayudu and published by CRC Press. This book was released on 2019-06-04 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1983, this book offers a full, comprehensive guide into the relationship between Radiotracers and the methods in which they are applied in the field of medicine. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Radiology, and other practitioners in their respective fields.
Download or read book Radiotracer Methodology in the Biological Environmental and Physical Sciences written by Chih Hsing Wang and published by Prentice Hall. This book was released on 1975 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atoms and nuclides. The nature of radioactive decay. Characteristics of ionizing radiation. Nuclear instrumentation. Measurements of radioactivity: general considerations and the methods based on gas ionization. Gamma ray counting using solid scintillators. Gamma ray spectrometry using solid scintillatio detectors. Semiconductor radiation detectors. Measurement of radioactivity by the liquid (Internal-Sample) scintillation method. Measurement of radioactivity by emulsion and track detectors. Preparation of counting samples. Nuclear statistics. Correction factors in radiotracer assay. Design and execution of radiotracer experiments. Availability of radioisotope-labeled compounds. Nuclear safety. Radioanalytical techniques. Environmental applications of radiotracers. Tracer applications in the physical sciences. Nuclear reaction calculations.
Download or read book Radiotracer Techniques and Applications written by Eustace Anthony Evans and published by . This book was released on 1977 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Radiotracer Methodology in Biological Science written by David L. Willis and published by . This book was released on 1963 with total page 1202 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of radioactive isotopes as tracers in biological systems has become widespread since the close of World War II. Proper use of radiotracers requires a fundamental understanding of the physical nature of radioactivity, the characteristics of ionizing radiation, and the various methods available for measuring radioactivity. More importantly, the investigator employing radioisotopic tracers must be familiar with the methodology involved in design of radio-tracer experiments, the preparation of radioactive samples for assay, and the problems inherent in analyzing data from radiotracer experiments. The purpose in the preparation of this thesis was to present a summary of the essential concepts and information needed by the biologist who desires to make use of radiotracer methods in his investigations. The thesis is set forth in the form of an introductory text, suitable either for class or individual use. The presentation is divided into three major sections (1) the text proper, covering the principles of radiotracer methodology, (2) a set of basic laboratory exercises, intended to familiarize the user with procedures in detecting and characterizing radioactivity, and (3) a selection of typical radiotracer experiments illustrating applications in various fields of biological science. This latter section is thought to be particularly valuable in that it furnishes step-by-step examples of design and execution of typical radiotracer experiments In view of the fact that liquid scintillation counting has recently come into widespread favor among biologists using tritium and carbon-14 labeled tracer compounds and yet no comprehensive monograph is available on the subject, particular attention has been devoted to this assay method. A most extensive bibliography covering both the preparation of samples for liquid scintillation counting and the operating characteristics of the counter assembly is included. In addition, one of the laboratory exercises deals with the practical operation of a liquid scintillation counter Other aspects of radiotracer methodology that are treated are the safe handling of radioisotopes, the proper design of radiotracer laboratory facilities, and the statistical analysis of counting data. Since the biologist commonly secures his radiotracer compounds from commercial radiochemical. suppliers, a chapter on the methods of primary radioisotope production and the preparation of labeled compounds has been included as background information. The recently popular technique of tritium labeling by gas-exposure (the Wilzbach method) has also been discussed in this connection. Although the emphasis in this presentation has been restricted primarily to the application of radiotracers to research in the biological sciences, the coverage is broad enough to be of value to investigators in other fields.
Download or read book Radiopharmaceutical Chemistry written by Jason S. Lewis and published by Springer. This book was released on 2019-04-02 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide to radiopharmaceutical chemistry. The stunning clinical successes of nuclear imaging and targeted radiotherapy have resulted in rapid growth in the field of radiopharmaceutical chemistry, an essential component of nuclear medicine and radiology. However, at this point, interest in the field outpaces the academic and educational infrastructure needed to train radiopharmaceutical chemists. For example, the vast majority of texts that address radiopharmaceutical chemistry do so only peripherally, focusing instead on nuclear chemistry (i.e. nuclear reactions in reactors), heavy element radiochemistry (i.e. the decomposition of radioactive waste), or solely on the clinical applications of radiopharmaceuticals (e.g. the use of PET tracers in oncology). This text fills that gap by focusing on the chemistry of radiopharmaceuticals, with key coverage of how that knowledge translates to the development of diagnostic and therapeutic radiopharmaceuticals for the clinic. The text is divided into three overarching sections: First Principles, Radiochemistry, and Special Topics. The first is a general overview covering fundamental and broad issues like “The Production of Radionuclides” and “Basics of Radiochemistry”. The second section is the main focus of the book. In this section, each chapter’s author will delve much deeper into the subject matter, covering both well established and state-of-the-art techniques in radiopharmaceutical chemistry. This section will be divided according to radionuclide and will include chapters on radiolabeling methods using all of the common nuclides employed in radiopharmaceuticals, including four chapters on the ubiquitously used fluorine-18 and a “Best of the Rest” chapter to cover emerging radionuclides. Finally, the third section of the book is dedicated to special topics with important information for radiochemists, including “Bioconjugation Methods,” “Click Chemistry in Radiochemistry”, and “Radiochemical Instrumentation.” This is an ideal educational guide for nuclear medicine physicians, radiologists, and radiopharmaceutical chemists, as well as residents and trainees in all of these areas.
Download or read book Advancing Nuclear Medicine Through Innovation written by National Research Council and published by National Academies Press. This book was released on 2007-09-11 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.
Download or read book Handbook of Radiopharmaceuticals written by Michael R. Kilbourn and published by John Wiley & Sons. This book was released on 2021-04-12 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: The thoroughly updated new edition of the authoritative reference in Radiopharmaceutical Sciences The second edition of Handbook of Radiopharmaceuticals is a comprehensive review of the field, presenting up-to-date coverage of central topics such as radionuclide production, synthetic methodology, radiopharmaceutical development and regulations, and a wide range of practical applications. A valuable reference work for those new to the Radiopharmaceutical Sciences and experienced professionals alike, this volume explores the latest concepts and issues involving both targeted diagnostic and therapeutic radiopharmaceuticals. Contributions from a team of experts from across sub-disciplines provide readers with an immersive examination of radiochemistry, nuclear medicine, molecular imaging, and more. Since the first edition of the Handbook was published, Nuclear Medicine and Radiopharmaceutical Sciences have undergone major changes. New radiopharmaceuticals for diagnosis and therapy have been approved by the FDA, the number of clinical PET and SPECT scans have increased significantly, and advances in Artificial Intelligence have dramatically improved research techniques. This fully revised edition reflects the current state of the field and features substantially updated and expanded content. New chapters cover topics including current Good Manufacturing Practice (cGMP), regulatory oversight, novel approaches to quality control—ensuring that readers are informed of the exciting developments of recent years. This important resource: Features extensive new and revised content throughout Covers key areas of application for diagnosis and therapy in oncology, neurology, and cardiology Emphasizes the multidisciplinary nature of Radiopharmaceutical Sciences Discusses how drug companies are using modern radiopharmaceutical imaging techniques to support drug discovery Examines current and emerging applications of Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) Edited by recognized experts in radiochemistry and PET imaging, Handbook of Radiopharmaceuticals: Radiochemistry and Applications, 2 nd Edition is an indispensable reference for post-doctoral fellows, research scientists, and professionals in the pharmaceutical industry, and for academics, graduate students, and newcomers in the field of radiopharmaceuticals.
Download or read book Biological Transport of Radiotracers written by Lelio Colombetti and published by CRC Press. This book was released on 2020-04-28 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1982: The book attempts to explain transport processes for radiolabelled tracers.
Download or read book Targeted Radionuclide Therapy written by Tod W. Speer and published by Lippincott Williams & Wilkins. This book was released on 2012-03-28 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.
Download or read book Radiotracers for Medical Applications written by Garimella V. S. Rayudu and published by CRC Press. This book was released on 2019-06-11 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1983, this book offers a full, comprehensive guide into the relationship between Radiotracers and the methods in which they are applied in the field of medicine. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Radiology, and other practitioners in their respective fields.
Download or read book Nuclear Medicine Physics written by Dale L. Bailey and published by . This book was released on 2015-03-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication provides the basis for the education of medical physicists initiating their university studies in the field of nuclear medicine. The handbook includes 20 chapters and covers topics relevant to nuclear medicine physics, including basic physics for nuclear medicine, radionuclide production, imaging and non-imaging detectors, quantitative nuclear medicine, internal dosimetry in clinical practice and radionuclide therapy. It provides, in the form of a syllabus, a comprehensive overview of the basic medical physics knowledge required for the practice of medical physics in modern nuclear medicine.
Download or read book Handbook of Radiopharmaceuticals written by Michael J. Welch and published by John Wiley & Sons. This book was released on 2003-01-17 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States
Download or read book Molecular Imaging written by Shankar Vallabhajosula and published by Springer Science & Business Media. This book was released on 2009-07-13 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.
