Download or read book Biointegration of Medical Implant Materials written by Chandra P. Sharma and published by Elsevier. This book was released on 2010-07-13 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue.Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering.With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector. - Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration - Discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction - Reviews particular techniques in drug delivery featuring inorganic nanoparticles and functionalized nanoparticles for targeted drug delivery

Download or read book Biointegration of Medical Implant Materials written by Chandra P. Sharma and published by Woodhead Publishing. This book was released on 2019-09-17 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biointegration of Medical Implant Materials, Second Edition, provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. New sections discuss soft tissue integration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. Other sections review tissue regeneration, inorganic nanoparticles for targeted drug delivery, alginate based drug delivery devices, and design considerations, with coverage of the biocompatibility of materials and their relevance to drug delivery and tissue engineering. With its distinguished editor and team of international contributors, this book is ideal for medical materials scientists and engineers in industry and academia. - Provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration - Discusses soft tissue biointegration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, vascular grafts and replacement materials for facial reconstruction - Includes new information on a variety of tissue regeneration techniques and applications

Download or read book Biomaterials in Translational Medicine written by Lei Yang and published by Academic Press. This book was released on 2018-11-30 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. - Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine - Includes the translational or commercialization status of these new biomaterials - Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine - Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials

Download or read book Bioscience and Bioengineering of Titanium Materials written by Yoshiki Oshida and published by Elsevier. This book was released on 2010-07-07 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique book about bioscience and the bioengineering of titanium materials is based on more than 1,000 published articles. It bridges the gap between the medical/dental fields and the engineering/technology areas, due to the author's unique experience in both during the last 30 years. The book covers Materials Classifications, Chemical and Electrochemical Reactions, Oxidation, Biological Reactions, Implant-related Biological Reactions, Applications, Fabri-cation Technologies, Surface Modifications, and Future Perspectives.* Provides quick access to the primary literature in this field* Reviews studies of titanium materials in medical and dental applications, as reported in nearly 1,500 articles published over last several years* Draws information from several types of studies and reports* Helps readers answer questions about the most appropriate materials and when to use them

Download or read book Bio Tribocorrosion in Biomaterials and Medical Implants written by Yu Yan and published by Elsevier. This book was released on 2013-09-30 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: During their service life, most biomaterials and medical implants are vulnerable to tribological damage. In addition, the environments in which they are placed are often corrosive. The combination of triobology, corrosion and the biological environment has been named 'bio-tribocorrosion'. Understanding this complex phenomenon is critical to improving the design and service life of medical implants. This important book reviews recent key research in this area.After an introduction to the topography of bio-tribocorrosion, Part one discusses different types of tribocorrosion including fatigue-corrosion, fretting-corrosion, wear-corrosion and abrasion-corrosion. The book also discusses the prediction of wear in medical devices. Part two looks at biological effects on tribocorrosion processes, including how proteins interact with material surfaces and the evolution of surface changes due to bio-tribocorrosion resulting from biofilms and passive films. Part three reviews the issue of bio-tribocorrosion in clinical practice, including dental applications and joint replacement as well the use of coatings and test methods for bio-tribocorrosion.With its international team of contributors, Bio-tribocorrosion in biomaterials and medical implants is a standard reference for those researching and developing medical devices as well as clinicians in such areas as dentistry and orthopaedic surgery. - Reviews recent research in bio-tribocorrosion and its role in improving the design and service life of medical implants - Discusses types of bio-tribocorrosion including fatigue and wear corrosion - Examines biological effects on bio-tribocorrosion processes including interaction of proteins with metal surfaces

Download or read book Functional Bio based Materials for Regenerative Medicine From Bench to Bedside Part 2 written by Mohd Fauzi Mh Busra, Daniel Law Jia Xian, Yogeswaran Lokanathan, Ruszymah Haji Idrus and published by Bentham Science Publishers. This book was released on 2024-02-02 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside explores the use of bio-based materials for the regeneration of tissues and organs. The book presents an edited collection of 28 topics in 2 parts focused on the translation of these materials from laboratory research (the bench) to practical applications in clinical settings (the bedside). Chapter authors highlight the significance of bio-based materials, such as hydrogels, scaffolds, and nanoparticles, in promoting tissue regeneration and wound healing. Topics in the book include: - the properties of bio-based materials, including biocompatibility, biodegradability, and the ability to mimic the native extracellular matrix. - fabrication techniques and approaches for functional bio-based material design with desired characteristics like mechanical strength and porosity to promote cellular attachment, proliferation, and differentiation - the incorporation of bioactive molecules, such as growth factors, into bio-based materials to enhance their regenerative potential. - strategies for the controlled release of molecules to create a favorable microenvironment for tissue regeneration. - the challenges and considerations involved in scaling up the production of bio-based materials, ensuring their safety and efficacy, and obtaining regulatory approval for clinical use Part 2 covers advanced materials and techniques used in tissue engineering. Topics focus on advanced composite materials for 3D scaffolds and the repair of tissues in different organs such as the heart, cornea, bone and ligaments. Materials highlighted in this part include polyamide composites, electrospun nanofibers, and different bio-based hydrogels. Functional Bio-based Materials for Regenerative Medicine: From Bench to Bedside is a valuable reference for researchers in biomedical engineering, cell biology, and regenerative medicine who want to update their knowledge on current developments in the synthesis and application of functional biomaterials.

Download or read book Surgical Ophthalmic Oncology written by Sonal S. Chaugule and published by Springer Nature. This book was released on 2019-10-03 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as an easy-to-use, practical guide to tumors of the eye, lids, and orbit, this Open Access book comprehensively addresses surgical treatment and management of diseases related to ophthalmic oncology. Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is an ideal reference for general ophthalmologists, surgeons, fellows and trainees around the world who encounter these diseases in the care of their patients. Notably, this book includes considerations for those ophthalmologists offering subspecialty care in environments with limited access to advanced technology and instrumentation. Individual chapters address diagnostic indications, pre-operative and post-operative concerns, and provide detailed explanations of surgical techniques required to manage various eye cancer ailments with help of ample illustrations. High-quality videos included throughout the book provide readers with the opportunity to review surgical steps in real-time as a learning tool. Chapters thoroughly cover tumors of eyelid, cornea and conjunctiva, orbit as well as intraocular tumors, while later chapters discuss ophthalmic radiation therapy. The book concludes with a section on ophthalmic pathology which details essential guidelines on relevant aspects from specimen collection and transport, to interpretation of the pathology report. Surgical Ophthalmic Oncology: A Collaborative Open Access Reference is a unique and necessary valuable resource for ophthalmologists, trainees, and related medical professionals working in underserved areas in providing quality care for patients suffering from ocular cancers.

Download or read book Oral Delivery of Insulin written by T.A. Sonia and published by Elsevier. This book was released on 2014-12-11 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes Mellitus, a syndrome of disordered metabolism, characterised by abnormal elevation in blood glucose level, has become a life-threatening condition for many people. Current means of therapy for Diabetes Mellitus do not mimic the normal physiological pattern of insulin release. Oral delivery is the preferred route of administration due to its non-invasive nature. Oral delivery of insulin presents an overview of Diabetes Mellitus, and discusses the strategies and techniques adopted for oral delivery of insulin. This title begins with an introductory chapter on symptoms, complications and therapy for Diabetes Mellitus. Subsequent chapters cover the various routes for administering insulin; the challenges and strategies of oral delivery; experimental techniques in the development of an oral insulin carrier; lipids; inorganic nanoparticles and polymers in oral insulin delivery; and a summary and presentation of future perspectives on oral delivery of insulin. - Presents an overview of Diabetes Mellitus - Includes a discussion of various strategies and techniques adopted for oral delivery of insulin - Presents an update of research in the field

Download or read book Advanced Biomaterials written by Bikramjit Basu and published by John Wiley & Sons. This book was released on 2010-07-02 with total page 778 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enables readers to take full advantage of the latest advances in biomaterials and their applications. Advanced Biomaterials: Fundamentals, Processing, and Applications reviews the latest biomaterials discoveries, enabling readers to take full advantage of the most recent findings in order to advance the biomaterials research and development. Reflecting the nature of biomaterials research, the book covers a broad range of disciplines, including such emerging topics as nanobiomaterials, interface tissue engineering, the latest manufacturing techniques, and new polymeric materials. The book, a contributed work, features a team of renowned scientists, engineers, and clinicians from around the world whose expertise spans the many disciplines needed for successful biomaterials development. All readers will gain an improved understanding of the full range of disciplines and design methodologies that are used to develop biomaterials with the physical and biological properties needed for specific clinical applications.

Download or read book Bioinspired Structures and Design written by Wole Soboyejo and published by Cambridge University Press. This book was released on 2020-09-17 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master simple to advanced biomaterials and structures with this essential text. Featuring topics ranging from bionanoengineered materials to bio-inspired structures for spacecraft and bio-inspired robots, and covering issues such as motility, sensing, control and morphology, this highly illustrated text walks the reader through key scientific and practical engineering principles, discussing properties, applications and design. Presenting case studies for the design of materials and structures at the nano, micro, meso and macro-scales, and written by some of the leading experts on the subject, this is the ideal introduction to this emerging field for students in engineering and science as well as researchers.

Download or read book Biomaterials and Regenerative Medicine in Ophthalmology written by Traian Chirila and published by Elsevier. This book was released on 2009-12-18 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients' quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction.With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology. - Reviews the increasingly important role of biomaterials and regenerative medicine in the advancement of ophthalmology and optometry - Provides an overview of the present status and future direction of biomaterials and regenerative medicine in this important field - Discusses applications in both the anterior and prosterior segments of the eye with chapters on such topics as synthetic corneal implants and retinal repair and regeneration

Download or read book Host Response to Biomaterials written by Stephen F. Badylak and published by Academic Press. This book was released on 2015-05-08 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine. - Explains the various categories of biomaterials and their significance for clinical applications - Contains a range of extensive coverage, including, but not limited to, orthopedic, surgery, dental, general surgery, neurosurgery, lower urinary tract, and regenerative medicine - Includes regulations regarding combination devices

Download or read book Coatings for Biomedical Applications written by Mike Driver and published by Elsevier. This book was released on 2012-02-22 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications.The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices.With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings. - Provides an extensive review of coating types and surface modifications for biomedical applications - Chapters look at hydrophilic coatings for biomedical applications in and ex vivo, mineral coatings for orthopaedic applications, pyrolytic carbon coating and other commonly-used biomedical coatings - Presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices

Download or read book Regenerative Medicine and Plastic Surgery written by Dominik Duscher and published by Springer Nature. This book was released on 2019-11-26 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the current research concepts and the emerging technologies in the field of stem cells and tissue engineering. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner. Divided into five parts, the book opens with a description of the elements of regenerative medicine including definitions, basic principles of soft and bone tissue regeneration, biomaterials and scaffolds. Current research concepts are explored in the second part of this book, for example mechanotransduction and the utility of extracellular vesicles. In the third part, the editors present the emerging technologies and highlight the novel perspectives on bionic reconstruction and biomimetics in surgery and regenerative medicine. Part four deals with translational aspects including practical information on moving scientific findings from bench to bedside. The final part then describes in detail applications in clinical plastic surgery. Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties. "In your hands is a comprehensive encyclopedia of two rapidly converging fields. Drs Duscher and Shiffman have done an outstanding job of highlighting the interdependent relationship between plastic surgery and regenerative medicine. Ultimately, this is to the benefit of both fields." - Geoffrey C. Gurtner, MD, FACS Johnson and Johnson Distinguished Professor of Surgery Professor (by courtesy) of Bioengineering and Materials Science Inaugural Vice Chairman of Surgery for Innovation Stanford University School of Medicine

Download or read book Sterilisation of Biomaterials and Medical Devices written by Sophie Lerouge and published by Elsevier. This book was released on 2012-09-27 with total page 347 pages. Available in PDF, EPUB and Kindle. Book excerpt: The effective sterilisation of any material or device to be implanted in or used in close contact with the human body is essential for the elimination of harmful agents such as bacteria. Sterilisation of biomaterials and medical devices reviews established and commonly used technologies alongside new and emerging processes.Following an introduction to the key concepts and challenges involved in sterilisation, the sterilisation of biomaterials and medical devices using steam and dry heat, ionising radiation and ethylene oxide is reviewed. A range of non-traditional sterilisation techniques, such as hydrogen peroxide gas plasma, ozone and steam formaldehyde, is then discussed together with research in sterilisation and decontamination of surfaces by plasma discharges. Sterilisation techniques for polymers, drug-device products and tissue allografts are then reviewed, together with antimicrobial coatings for 'self-sterilisation' and the challenge presented by prions and endotoxins in the sterilisation of reusable medical devices. The book concludes with a discussion of future trends in the sterilisation of biomaterials and medical devices.With its distinguished editors and expert team of international contributors, Sterilisation of biomaterials and medical devices is an essential reference for all materials scientists, engineers and researchers within the medical devices industry. It also provides a thorough overview for academics and clinicians working in this area. - Reviews established and commonly used technologies alongside new and emerging processes - Introduces and reviews the key concepts and challenges involved in sterilisation - Discusses future trends in the sterilisation of biomaterials and medical devices

Download or read book Biomaterials and Medical Device Associated Infections written by L Barnes and published by Elsevier. This book was released on 2014-11-21 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection. - Provides analysis of biofilms and their relevance to implant associated infections. - Assesses technologies for controlling biofilms. - Considers advantages and disadvantages of in vivo infection studies.

Download or read book Biomaterial Related Infections written by Natália Martins and published by MDPI. This book was released on 2020-12-23 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of medical devices (e.g., catheters, implants, and probes) is a common and essential part of medical care for both diagnostic and therapeutic purposes. However, these devices quite frequently lead to the incidence of infections due to the colonization of their abiotic surfaces by biofilm-growing microorganisms, which are progressively resistant to antimicrobial therapies. Several methods based on anti-infective biomaterials that repel microbes have been developed to combat device-related infections. Among these strategies, surface coating with antibiotics (e.g., beta-lactams), natural compounds (e.g., polyphenols), or inorganic elements (e.g., silver and copper nanoparticles) has been widely recognized as exhibiting broad-spectrum bactericidal or bacteriostatic activity. So, in order to achieve a better therapeutic response, it is crucial to understand how these infections are different from others. This will allow us to find new biomaterials characterized by antifouling coatings with repellent properties or low adhesion towards microorganisms, or antimicrobial coatings that are capable of killing microbes approaching the surface, improving biomaterial functionalization strategies and supporting tissues’ bio-integration.