Download or read book Benefits Assessment written by J.D. Bentkover and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years there has been substantial interest in benefits assessment methods, especially as these methods are used to assess health, safety, and environmental issues. At least part of this interest can be traced to Executive Order 12291, issued by President Ronald Reagan in 1981. This Executive Order requires Federal agencies to perform benefits assessments of pro posed major regulations and prohibits them from taking regulatory action unless potential benefits exceed potential costs to society. Heightened interest in benefits assessment methods has in tum given rise to greater recognition of the inherent difficulties in performing such assess ments. For example, many benefits that are intuitively felt to be most important are also among the most difficult to measure. It can be difficult to identify the full range of both benefits and costs. The choice of an appro priate discount rate for comparing benefits and costs over time is proble matic. Even when benefits are quantifiable in principle and agreement can be reached on their valuation, required d,ata may not be available. Thus considerable uncertainty is built into most benefit estimates, even when they are based on the best available data. In light of the complexities and difficulties associated with the perform ance of a benefits assessment, this book reviews the current state of theoretical and methodological knowledge in the field. The review is extensive in that it covers over fifty years of research, theoretical develop ment, and practice.
Download or read book Fungicide Benefits Assessment written by and published by . This book was released on 1991 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Development of Methods for Benefits Assessment of ITS Deployment in Wisconsin written by and published by . This book was released on 2004 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book An Assessment of Economic Benefits of 28 Projects in the Section 314 Clean Lakes Program written by Thomas E. Walton and published by . This book was released on 1980 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biologic and Economic Assessment of Benefits from Use of Phenoxy Herbicides in the United States written by and published by . This book was released on 1996 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Project IV The benefits and costs of Superfund cleanups an information assessment written by Center for Hazardous Waste Management and published by . This book was released on 1989 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Assessment of the Benefits of Extending the Tropical Rainfall Measuring Mission written by National Research Council and published by National Academies Press. This book was released on 2006-09-22 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Launched jointly in 1997 by the National Aeronautics and Space Administration (NASA) and the Japan Aerospace Exploration Agency (JAXA), the Tropical Rainfall Measuring Mission (TRMM) is a satellite mission that placed a unique suite of instruments, including the first precipitation radar, in space. These instruments are used to monitor and predict tropical cyclone tracks and intensity, estimate rainfall, and monitor climate variability (precipitation and sea surface temperature). TRMM has been collecting data for seven years; this data is used by the Joint Typhoon Warning Center, the National Center for Environmental Prediction, and the National Hurricane Center, among others worldwide. In July 2004, NASA announced that it would terminate TRMM in August 2004. At the request of the National Oceanic and Atmospheric Administration (NOAA), the White House, and the science community, NASA agreed to continue TRMM operations through the end of 2004. Meanwhile, NASA asked a National Research Council (NRC) committee to provide advice on the benefits of keeping TRMM in operation beyond 2004. After holding a workshop with a number of experts in the field, the committee found that TRMM will contribute significantly to operations and science if the mission is extended; and therefore, strongly recommends continued operation of TRMM with the caveat that cost and risk will need to be further examined before a final decision about the future of TRMM can be made.
Download or read book Characterizing and Communicating Uncertainty in the Assessment of Benefits and Risks of Pharmaceutical Products written by Institute of Medicine and published by National Academies Press. This book was released on 2014-12-19 with total page 123 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite the extensive body of evidence that informs regulatory decisions on pharmaceutical products, significant uncertainties persist, including the underlying variability in human biology, factors associated with the chemistry of a drug, and limitations in the research and clinical trial process itself that might limit the generalizability of results. As a result, regulatory reviewers are consistently required to draw conclusions about a drug's safety and efficacy from imperfect data. Efforts are underway within the drug development community to enhance the evaluation and communication of the benefits and risks associated with pharmaceutical products, aimed at increasing the predictability, transparency, and efficiency of pharmaceutical regulatory decision making. Effectively communicating regulatory decisions necessarily includes explanation of the impact of uncertainty on decision making. On February 12 and May 12, 2014, the Institute of Medicine's Forum on Drug Discovery, Development, and Translation held public workshops to advance the development of more systematic and structured approaches to characterize and communicate the sources of uncertainty in the assessment of benefits and risks, and to consider their implications for pharmaceutical regulatory decisions. Workshop presentations and discussions on February 12 were convened to explore the science of identifying and characterizing uncertainty in scientific evidence and approaches to translate uncertainties into decisions that reflect the values of stakeholders. The May 12 workshop presentations and discussions explored tools and approaches to communicating about scientific uncertainties to a range of stakeholders in the drug development process. Characterizing and Communicating Uncertainty in the Assessment of Benefits and Risks of Pharmaceutical Products summarizes the presentation and discussion of both events. This report explores potential analytical and communication approaches and identifies key considerations on their development, evaluation, and incorporation into pharmaceutical benefit- risk assessment throughout the entire drug development lifecycle.
Download or read book Benefit Risk Assessment of Medicines written by James Leong and published by Springer. This book was released on 2015-04-21 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book proposes and investigates a universal framework, and accompanying documentation system, to facilitate and catalogue benefit-risk decisions; a valuable addition to the benefit-risk toolbox. Over the past decade, pharmaceutical companies and regulatory agencies have been reviewing the benefit-risk assessment of medicines with a view to developing a structured, systematic, standardized approach. Examining the evaluation of such an approach by several mature regulatory authorities ensures that the reader gains a unique insight into the ongoing debate in this area. The field of benefit-risk assessment continues to evolve at a rapid pace due to political and societal pressure, as is reflected in the recent FDA PUDFA agreement as well as in the EMA 2015 Roadmap. Rather than provide a comprehensive snap-shot of this constantly changing environment, this book evaluates selected current approaches to benefit-risk assessment. The strengths and weaknesses of publicly available documents in communicating benefit-risk decisions to stakeholders are reviewed and these evaluations are used to inform development of a prospective framework that could be used to harmonise procedures globally.
Download or read book Benefits Assessment written by J. D. Bentkover and published by . This book was released on 2014-01-15 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Power of Assessment for Learning written by Margaret Heritage and published by Corwin. This book was released on 2019-11-15 with total page 145 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enrich, grow, and sustain AfL in your classroom. Twenty years after the publication of Inside the Black Box, the landmark review of formative classroom assessment, international education experts Christine Harrison and Margaret Heritage tackle assessment for learning (AfL) anew, with fresh insights gained from two decades of research, theory, and classroom practice. Packed with key AfL ideas and supports, vignettes that illustrate AfL in action, and practice-based evidence to enrich understanding of AfL from both the teacher’s and the student’s perspectives, this book is a ‘sounding board’ for educators to explore and reflect on their own AfL practices and beliefs.
Download or read book Benefit Risk Assessment Methods in Medical Product Development written by Qi Jiang and published by CRC Press. This book was released on 2017-12-19 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: Guides You on the Development and Implementation of B–R Evaluations Benefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks and quantitative methods. Leading experts from industry, regulatory agencies, and academia present practical examples, lessons learned, and best practices that illustrate how to conduct structured B–R assessment in clinical development and regulatory submission. The first section of the book discusses the role of B–R assessments in medicine development and regulation, the need for both a common B–R framework and patient input into B–R decisions, and future directions. The second section focuses on legislative and regulatory policy initiatives as well as decisions made at the U.S. FDA’s Center for Devices and Radiological Health. The third section examines key elements of B–R evaluations in a product’s life cycle, such as uncertainty evaluation and quantification, quantifying patient B–R trade-off preferences, ways to identify subgroups with the best B–R profiles, and data sources used to assist B–R assessment. The fourth section equips practitioners with tools to conduct B–R evaluations, including assessment methodologies, a quantitative joint modeling and joint evaluation framework, and several visualization tools. The final section presents a rich collection of case studies. With top specialists sharing their in-depth knowledge, thought-provoking considerations, and practical advice, this book offers comprehensive coverage of B–R evaluation methods, tools, and case studies. It gives practitioners a much-needed toolkit to develop and conduct their own B–R evaluations.
Download or read book Assessing the Benefits of Benefit Assessments written by and published by . This book was released on 1995 with total page 46 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A Treatise on the Law of Taxation by Local and Special Assessments written by William Herbert Page and published by . This book was released on 1909 with total page 1382 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Compiled Statutes of New Jersey abatement civil service written by New Jersey and published by . This book was released on 1911 with total page 1702 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Lawyers Reports Annotated written by and published by . This book was released on 1910 with total page 1374 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lawyers Reports Annotated written by and published by . This book was released on 1902 with total page 1054 pages. Available in PDF, EPUB and Kindle. Book excerpt:
