Download or read book Basic Principles in Nucleic Acid Chemistry V2 written by Paul O.P. Ts'o and published by Elsevier. This book was released on 2012-12-02 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Principles in Nuclear Acid Chemistry, Volume II presents the significant progress in nucleic acid research and its contribution and influence on various aspects of human life. This book contains five chapters and begins with the susceptibility of nucleic acids towards attack by chemical reagents whose reactions with polynucleotides have been studied. This topic is followed by a presentation of experimental techniques used to study the properties of nucleic acids. The following chapter discusses some basic features embodied in the polyribo- and poly-deoxyribonucleotide backbone chains; the possibility of rotation around backbone bonds in the ""random"" single-stranded form; and the short- and long-range interactions in idealized and real chains. This chapter also looks into the thermodynamic and polyelectrolyte aspects of nucleic acid behavior. A chapter describes the special features of the third class of DNA, namely, closed duplex DNA, in which covalent chain scissions are absent. The last chapter examines the intrinsic properties and the interaction of the dimers and oligomers, with special emphasis on the influence of the phosphodiester linkages on the conformation and interaction of these short segments of nucleic acids. This book is of great value to workers in biomedical research and to higher level biochemistry instructors.
Download or read book Basic Principles in Nucleic Acid Chemistry written by Paul On Pong Ts'o and published by . This book was released on 1974 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Basic Principles in Nucleic Acid Chemistry V1 written by Paul O.P. Ts'o and published by Elsevier. This book was released on 2012-12-02 with total page 651 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Principles in Nucleic Acid Chemistry, Volume I provides information pertinent to the fundamental aspects of nucleic acids. This book discusses the development of the basic principles in nucleic acid research that will serve as a foundation for further advancement in nucleic acid research. Organized into six chapters, this volume begins with an overview of the history of the scientific study of nucleic acid as a genetic material. This text then examines the utility of the analogs of the naturally occurring nucleic acid components as biochemical tools and as therapeutic agents. Other chapters consider mass spectrometry that deals with the production and chemistry of ions in the vapor phase. This book discusses as well the various aspects of the excited states of the nucleic acids. The final chapter deals with the systematic study of the physiochemical properties of the monomeric units of nucleic acid. This book is a valuable resource for molecular biologists, scientists, and research workers.
Download or read book Principles of Nucleic Acid Structure written by Wolfram Saenger and published by Springer Science & Business Media. This book was released on 2013-12-01 with total page 574 pages. Available in PDF, EPUB and Kindle. Book excerpt: New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical ther modynamics are well represented by many excellent texts, and new or revised editions are published sufficiently often to keep up with progress in research. However, some areas of chemistry, especially many of those taught at the grad uate level, suffer from a real lack of up-to-date textbooks. The most serious needs occur in fields that are rapidly changing. Textbooks in these subjects usually have to be written by scientists actually involved in the research which is advancing the field. It is not often easy to persuade such individuals to set time aside to help spread the knowledge they have accumulated. Our goal, in this series, is to pinpoint areas of chemistry where recent progress has outpaced what is covered in any available textbooks, and then seek out and persuade experts in these fields to produce relatively concise but instructive introductions to their fields. These should serve the needs of one semester or one quarter graduate courses in chemistry and biochemistry. In some cases the availability of texts in active research areas should help stimulate the creation of new courses. CHARLES R. CANTOR New York Preface This monograph is based on a review on polynucleotide structures written for a book series in 1976.
Download or read book Principles of Nucleic Acid Structure written by Stephen Neidle and published by Elsevier. This book was released on 2010-07-26 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, Principles of Nucleic Acid Structure includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software. - Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA) - Includes a complete list of resources, including relevant online databases and software - Defines technical lingo for novices
Download or read book Photochemical Processes in Polymer Chemistry 2 written by G. Smets and published by Elsevier. This book was released on 2013-10-22 with total page 143 pages. Available in PDF, EPUB and Kindle. Book excerpt: Photochemical Processes in Polymer Chemistry-2 contains invited lectures presented at the Second IUPAC Symposium on Photochemical Processes in Polymer Chemistry held at Leuven, Belgium on June 2-4, 1976. This book contains 11 papers separated as chapters. Topics include energy transfer processes; photoinitiation of polymerization; solid-state polymerization mechanisms; photoinduced ionic polymerizations; and photoconductive polymers. This text also discusses energy transfer phenomena in high polymer systems; laser spectroscopical methods for the study of primary processes during the photodegradation; photooxidation of high polymers; and reaction selectivity and molecular association in photochemical reactions of nucleic acids and their constituents. New developments in photochromic polymers and related phenomena, as well as the design of photoreactive polymer systems for imaging processes are also explained.
Download or read book Nucleic Acids in Chemistry and Biology written by G. Michael Blackburn and published by Oxford University Press, USA. This book was released on 1996 with total page 556 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the discovery of the DNA double helix in 1953, nucleic acids have formed the central theme of much of contemporary molecular science. Recent mastery of nucleic acids synthesis has been the key to the establishment of the biotechnology industry, and our improving knowledge of nucleic acid structures and interactions is considerably influencing the design of novel drugs. The first edition of this book responded to the pressing need for a single volume that integrated the chemistry and biology of the nucleic acids in an introductory yet authoritative text. This second and completely updated edition, which includes a new chapter on techniques applied to nucleic acids, sets the basics of the nucleic acids in the context of the expanding horizons set by modern structural biology, RNA enzymology, drug discovery and biotechnology.
Download or read book Chemistry of Nucleosides and Nucleotides written by L.B. Townsend and published by Springer Science & Business Media. This book was released on 2013-03-07 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present volume is the first of a projected four-volume treatise. This volume contains the following chapters: "Synthesis and Reaction of Pyrimidine Nucleosides," "Synthesis and Properties of Purine Nucleosides and Nucleotides," and "Synthesis and Properties of Oligonucleotides." These three chapters were selected for inclusion in Volume I because the areas have provided the basis and impetus for the initiation and development of the other areas of research, which will be described in subsequent volumes. Each chapter is rather comprehensive in nature and should provide a ready reference source for not only the novice but also the experienced investigator or researcher. The chapters have been prepared by authors with considerable experience in each particular area of research, and this has resulted in a lucid presentation of each well-defined area. These volumes were designed with medicinal chemists, medicinal organic chemists, organic chemists, carbohydrate chemists, physical chemists, and biological chemists in mind. However, because of the tremendous recent interest in this research area owing to the biological and chemotherapeutic evaluation of nucleosides and nucleotides as anticancer, antiviral, and antiparasitic agents, these volumes should also be valuable additions to the libraries of virologists, biochemical pharmacologists, oncologists, and pharmacologists. We would like to thank the authors for their enthusiasm and help in making these volumes available to the scientific community.
Download or read book Nucleic Acids Proteins and Carbohydrates written by F. Korte and published by Elsevier. This book was released on 2012-12-02 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methodicum Chimicum, Volume 11: Natural Compounds, Part 1: Nucleic acids, Proteins and Carbohydrates is devoted to the methods of structural determinations and syntheses of natural products. This text contains four chapters that include a short discussion of the principles of well-proved analytic procedures. It primarily describes the chemistry and biochemistry of nucleic acids, proteins, carbohydrates, and lipids. Other general topics covered include the components, chemical synthesis, sequences, primary structure, and classification of these macromolecules. This book is of value to chemists and scientists who works in associated areas, including medicine.
Download or read book Informational Biopolymers of Genes and Gene Expression written by Richard D. Blake and published by University Science Books. This book was released on 2005-03-23 with total page 812 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new text examines thebiophysics and biochemistry of nucleic acids and proteins, carving outthe dynamic interface between chemistry and molecular biology, and providing adetailed picture of nucleic acids and proteins, their structures, biologicalproperties, and origins and evolution.
Download or read book Organophosphorus Chemistry written by S Trippett and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes. The series will be of value to research workers in universities, government and industrial research organisations, whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study with a wide variety of applications, enabling the reader to rapidly keep abreast of the latest developments in their specialist areas. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book Progress in Biophysics and Molecular Biology written by J. A. V. Butler and published by Elsevier. This book was released on 2014-05-18 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Biophysics and Molecular Biology, Volume 32 summarizes the significant progress that has been made in the fields of biophysics and molecular biology. Topics range from metabolic regulation and transfer RNA to cellular metabolism and prokaryotic and eukaryotic ribosomes. This volume consists of five chapters and begins with a discussion of mathematical models used in the study of metabolic regulation, with emphasis on the energy metabolism of eukaryotes. The next chapter examines the possible functions of transfer RNA minor components, paying particular attention to the principle of location-function relationships. The reader is also introduced to spatial-functional correlations in cellular metabolism and highlights the role of organize multienzyme systems, along with the fundamentals of ribosome structure and function in prokaryotes and eukaryotes. A chapter that analyzes the structures and functions of transfer RNA concludes the book. This book will be of interest to scientists, students, and researchers working in the fields of biophysics and molecular biology.
Download or read book Organophosphorus Chemistry Volume 7 written by S. Trippett and published by Royal Society of Chemistry. This book was released on 1970 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation. Organophosphorus Chemistry provides a comprehensive annual review of the literature. Coverage includes phosphines and their chalcogenides, phosphonium salts, low coordination number phosphorus compounds, penta- and hexa-coordinated compounds, tervalent phosphorus acids, nucleotides and nucleic acids, ylides and related compounds, and phosphazenes. The series will be of value to research workers in universities, government and industrial research organisations, whose work involves the use of organophosphorus compounds. It provides a concise but comprehensive survey of a vast field of study with a wide variety of applications, enabling the reader to rapidly keep abreast of the latest developments in their specialist areas. Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.
Download or read book Long Range Charge Transfer in DNA II written by Gary B. Schuster and published by Springer Science & Business Media. This book was released on 2004-04-08 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts
Download or read book Biophysical Chemistry written by Charles R. Cantor and published by Macmillan. This book was released on 1980-06-15 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt: Three-part series remains the definitive text on the physical properties of biological macromolecules and the physical techniques used to study them. It is appropriate for a broad spectrum of advanced undergraduate and graduate courses and serves as a comprehensive reference for researchers. Part I: The Conformation of Biological Macromolecules 1980, paper, 365 pages, 158 illustrations 0-7167-1188-5 Part II: Techniques for the Study of Biological Structure and Function 1980, paper, 365 pages, 158 illustrations 0-7167-1190-7 Part III: The Behavior of Biological Macromolecules 1980, paper, 597 pages, 243 illustrations 0-7167-1192-3
Download or read book Mechanism of Action of Antieukaryotic and Antiviral Compounds written by Fred E. Hahn and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Antibiotics I was published in 1967, the teleological view was held by some that" antibiotics" were substances elaborated by certain microorgan isms for the purpose of competing with other microorganisms for survival in mixed ecological environments. However, not only had J. EHRLICH and his associates shown 15 years earlier that chloramphenicol was produced by Strepto myces venezuelae in cultures of sterilized soils but not in parallel cultures of the same soils which were not sterilized, but operationally, the search for anti cancer antibiotics was actively under way (Antibiotics I reporting on numerous such substances), although the concept of antibiosis could not logically justify such undertakings. This editor hesitates to accept the use of the term "antibiotic" for anti microbial agents of non microbiological origins which is sometimes encountered, but neither does he subscribe to the view that antibiotics are in some fundamental manner different from chemotherapeutic substances of other origins. Modes and mechanisms of action of chemotherapeutic compounds are not systematic functions of their origins nor of the taxonomical position of the target organisms. Consequently, in the selection of topics for Antibiotics III (published in 1975), synthetic drugs and natural products of higher plants (alkaloids) were represented, along with antibiotics in the strict sense of the definition. We now present Antibiotics V, for whose assembly the same selection criteria were applied as for Antibiotics Ill. The aggregate length of the contributions rendered it impractical to place the entire text between the covers of one book.
Download or read book Basic Principles in Nucleic Acid Chemistry written by Paul On Pong Ts'o and published by . This book was released on 1974 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:
