Download or read book Barrel Cortex written by Kevin Fox and published by Cambridge University Press. This book was released on 2008-03-20 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: The barrel cortex contains the somatosensory representation of the whiskers on the face of the rodent and forms an early stage of cortical processing for tactile information. It is an area of great importance for understanding how the cerebral cortex works because the cortical columns that form the basic building blocks of the cerebral cortex can be seen within the barrel cortex. In this advanced graduate and research level text, Kevin Fox explores three main aspects of the barrel cortex: development, sensory processing and plasticity. Initial chapters introduce the topic, describing those animals that have barrels, the functional anatomy of the system and the cellular and synaptic physiology of the cortical microcircuit. The book concludes with a chapter covering the numerous fields where the barrel cortex is used as a model system for solving problems in other areas of research, including stroke, angiogenesis and understanding active touch.
Download or read book The Barrel Cortex of Rodents written by Alan Peters and published by Springer Science & Business Media. This book was released on 1995-01-31 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 11 examines the many methodologies that researchers use to investigate the barrel cortex.
Download or read book The Barrel Cortex of Rodents written by Edward G. Jones and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: The barrel area is a unique specialization of the cerebral cortex, shared by many species of rodents and some marsupials, in which the somatotopic map of the body surface receives direct morphological expression. Here, the homogeneous sheet of layer IV granule cells seen in most mammals is fractured into large archipelagos, each representing one of the larger subdivisions of the contra lateral half-body. Within these larger domains are smaller aggregates of granule cells that contain the concentrated terminations of thalamocortical fibers bear ing messages emanating from constellations of receptors located in finer subdi visions of a body part. These smaller aggregates are particularly well-defined in the representation of the face, where they form a one-to-one representation of the sinus hairs or vibrissae and where they have been given the name barrels. The first inklings of the unique structure of the parietal cortex of rodents came in the study of Droogleever-Fortuyn (1914), who remarked on the pres ence in it of clouds of granule cells 0. 5-1 mm in diameter, which he thought were in some way associated with concentrations of nerve fibers. Little attention, however, was paid to his observations. Lorente de N 6 (1922) later observed dense focal concentrations of afferent fiber ramifications in Golgi preparations of the mouse cortex, calling them glomeruli, and these can now be seen as the structures that form the hearts of the barrels and around which the granule cells concentrate.
Download or read book Neuronal Dynamics written by Wulfram Gerstner and published by Cambridge University Press. This book was released on 2014-07-24 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This solid introduction uses the principles of physics and the tools of mathematics to approach fundamental questions of neuroscience.
Download or read book Methods for Neural Ensemble Recordings written by Miguel A. L. Nicolelis and published by CRC Press. This book was released on 2007-12-03 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensively updated and expanded, this second edition of a bestseller distills the current state-of-the-science and provides the nuts and bolts foundation of the methods involved in this rapidly growing science. With contributions from pioneering researchers, it includes microwire array design for chronic neural recordings, new surgical techniques for chronic implantation, microelectrode microstimulation of brain tissue, multielectrode recordings in the somatosensory system and during learning, as well as recordings from the central gustatory-reward pathways. It explores the use of Brain-Machine Interface to restore neurological function and proposes conceptual and technical approaches to human neural ensemble recordings in the future.
Download or read book Handbook of in Vivo Neural Plasticity Techniques written by and published by Academic Press. This book was released on 2018-09-01 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of in Vivo Neural Plasticity Techniques, Volume 28: A Systems Neuroscience Approach to the Neural Basis of Memory and Cognition gives a comprehensive overview of the current methods and approaches that are used to study neural plasticity from a systems neuroscience perspective. In addition, the book offers in-depth methodological advice that provides the necessary foundation for researchers establishing methods and students who need to understand the theoretical and methodological bases of these approaches. This is the ideal resource for anyone new to the study of cognitive and behavioral neuroscience who seeks an introduction to state-of-the-art techniques. - Offers a comprehensive overview of state-of-the-art approaches to studying neuroplasticity in vivo - Combines discussions of theoretical underpinnings with the methodological and technical aspects necessary to guarantee success - Arranged in a uniform format that clearly and concisely lays out descriptions, methods and the pitfalls of various techniques
Download or read book In Vivo Optical Imaging of Brain Function Second Edition written by Ron D. Frostig and published by CRC Press. This book was released on 2009-05-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.
Download or read book Handbook of Neural Activity Measurement written by Romain Brette and published by Cambridge University Press. This book was released on 2012-09-06 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Underlying principles of the various techniques are explained, enabling neuroscientists to extract meaningful information from their measurements.
Download or read book Neurotransmitter Release written by Hugo J. Bellen and published by Oxford University Press, USA. This book was released on 1999 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the reader with background information on neurotransmitter release. Emphasis is placed on the rationale by which proteins are assigned specific functions rather than just providing facts about function.
Download or read book Neural Plasticity in Adult Somatic Sensory Motor Systems written by Ford F. Ebner and published by CRC Press. This book was released on 2005-05-26 with total page 311 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizing current information about sensory-motor plasticity, Neural Plasticity in Adult Somatic Sensory-Motor Systems provides an up-to-date description of the dynamic processes that occur in somatic sensory-motor cortical circuits or somatic sensory pathways to the cortex due to experience, learning, or damage to the nervous system. The book e
Download or read book Micro Meso and Macro Dynamics of the Brain written by György Buzsáki and published by Springer. This book was released on 2016-05-02 with total page 181 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Each of these topics require appropriate levels of analyses with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks, supplemented by models and theories to explain how different levels of brain dynamics interact with each other and how the failure of such interactions results in neurologic and mental disease. While such complex questions cannot be answered exhaustively by a dozen or so chapters, this volume offers a nice synthesis of current thinking and work-in-progress on micro-, meso- and macro- dynamics of the brain.
Download or read book Neurobiology of Sensation and Reward written by Jay A. Gottfried and published by CRC Press. This book was released on 2011-03-28 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesizing coverage of sensation and reward into a comprehensive systems overview, Neurobiology of Sensation and Reward presents a cutting-edge and multidisciplinary approach to the interplay of sensory and reward processing in the brain. While over the past 70 years these areas have drifted apart, this book makes a case for reuniting sensation a
Download or read book Neural Circuit and Cognitive Development written by Bin Chen and published by Academic Press. This book was released on 2020-06-10 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neural Circuit and Cognitive Development, Second Edition, the latest release in the Comprehensive Developmental Neuroscience series, provides a much-needed update to underscore the latest research in this rapidly evolving field, with new section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume is devoted mainly to anatomical and functional development of neural circuits and neural systems and cognitive development. Understanding the critical role these changes play in neurodevelopment provides the ability to explore and elucidate the underlying causes of neurodevelopmental disorders and their effect on cognition. This series is designed to fill the knowledge gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. - Features leading experts in various subfields as section editors and article authors - Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship - Includes coverage of mechanisms that control the assembly of neural circuits in specific regions of the nervous system and multiple aspects of cognitive development
Download or read book The Rewiring Brain written by Arjen van Ooyen and published by Academic Press. This book was released on 2017-06-23 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists. - Reviews the current state of knowledge of structural plasticity in the adult brain - Gives a comprehensive overview of computational studies on structural plasticity - Provides insights into the potential driving forces of structural plasticity and the functional implications of structural plasticity for learning and memory - Serves as inspiration for developing novel treatment strategies for stimulating functional repair after brain damage
Download or read book The Newborn Brain written by Hugo Lagercrantz and published by Cambridge University Press. This book was released on 2010-01-07 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of the brain and the emergence of the mind constitute some of the most important concerns of contemporary biology. Disturbances during fetal life may have profound implications for a child's future neurological and psychological development, which can in turn impact society. The new edition of this highly respected work presents a comprehensive review of the basic mechanisms of brain development and the pathophysiology of disorders of the infant brain, written by a team of distinguished neuroscientists, neonatologists, and neuropediatricians. The book follows the main milestones of brain development, from formation of the neural tube and wiring of the neurons in the brain. Neurotrophic factors, neurotransmitters, glial cell biology, cerebral circulation development of sensory functions are all described in detail. Furthermore, there are more philosophical chapters on the evolution of the brain and the emergence of consciousness. Clinical considerations are highlighted where relevant.
Download or read book Wiring Principles of Cerebral Cortex written by Julian Budd and published by Frontiers Media SA. This book was released on 2015-11-17 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cerebral cortex is probably the most complex biological network. Here many millions of individual neurons, the functional units of cortex, are interconnected through a massive yet highly organized pattern of axonal and dendritic wiring. This wiring enables both near and distant cells to coordinate their responses and generate a rich variety of cognitions and behaviours. When the wiring is damaged through disease or trauma it may reorganize but this may lead to characteristic pathological behaviours. While there have been significant advances in mapping cortical connectivity, the organizing principles and function of this connectivity are not well understood. On the one hand, there appears to be general design constraints governing cortical wiring, as first recognised by Rámon y Cajal's in his laws of conduction, material, and volume conservation. Yet on the other hand, particular patterns of cortical wiring exist to serve specific functions. There is a wide gap in understanding how the response and connectivity properties of a single neuron contribute to emergent network functions such as in detecting perceptually relevant features. Unravelling this intimate causal relationship represents one of the major challenges in neuroscience. This Research Topic will examine progress in understanding cortical wiring principles. This Research Topic aims to draw together recent advances in methods and understanding as well as recent challenges to existing ideas about how cerebral cortex is wired. This is particularly timely because new automated techniques may soon yield huge datasets in need of explanation. Recent studies have, for instance, empirically evaluated Rámon y Cajal's conservation laws for cerebral cortex, while others have shown some unexpected connectivity features that may refine the traditional view of how corticocortical connections are organised with regard to functional representations of auditory, somatosensory and visual cortices. Understanding these data will help improve the fidelity of neural models of cerebral cortical function and take into account the diversity of connections at both micro- and mesoscopic scales not seen at such a depth before.
Download or read book Cellular Migration and Formation of Neuronal Connections written by and published by Academic Press. This book was released on 2013-05-06 with total page 1081 pages. Available in PDF, EPUB and Kindle. Book excerpt: The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity
