Download or read book Atherosclerosis IV written by G. Schettler and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 835 pages. Available in PDF, EPUB and Kindle. Book excerpt: The presence of monotypism in thick atherosclerotic lesions of black females with G-6-PD mosaicism first reported by the Benditts (1973) has been confirmed in two other laboratories. However, we believe that it is premature to conclude that the finding of monotypism necessarily indicates monoclonal origin of athero sclerotic lesions. We have suggested two alternative explanations for the obser vation of monotypism which we believe must be shown to be invalid before accept ing monoclonal origin as the only plausible way to account for the observed G-6-PD monotypism. One of these two alternatives relates to clonal heterogeneity of cell growth potential, i. e. , during the course of progressive growth of a le sion, progeny of one cell may overgrow all others in a portion of the lesion. The other alternative is that one of the G-6-PD alleles may be linked to genes that afford a preferential survival characteristic in the abnormal environment present in atheroscerotic lesions. Thus, cells with one allele may be able to grow better than cells with the other allele, and this characteristic may be unrelated to "A-ness" or "B-ness". We have studied initiation of lesions in He diet-fed swine and demonstrated that all active lesions that were studied were of multiple cell origin (not monoclo nal). We have studied cell growth patterns in developing atherosclerotic lesions in He diet-fed swine and found evidence consistent with clonal heterogeneity in growth potential of lesion cells.
Download or read book Cardiovascular Disability written by Institute of Medicine and published by National Academies Press. This book was released on 2010-12-04 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.
Download or read book Atherosclerosis IV written by Fujio Numano and published by . This book was released on 1997 with total page 572 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest basic research on lipid metabolism, vascular biology, cytokines, fibrinolysis, and atherosclerosis is collected in this volume. The most recent treatments for this disorder, including treatment of restenosis by gene therapy, are discussed.
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Atherosclerosis written by Fujio Numano and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Atherosclerosis IV written by Fujio Numano and published by . This book was released on 1997 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Stroke Genetics written by Hugh S. Markus and published by Oxford Medical Publications. This book was released on 2003 with total page 362 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stroke is a major cause of death and the major cause of adult neurological disability in most of the world. Despite its importance on a population basis, research into the genetics of stroke has lagged behind that of many other disorders. However, the situation is now changing. Anincreasing number of single gene disorders causing stroke are being described, and there is growing evidence that polygenic factors are important in the risk of apparently "sporadic" stroke.Stroke Genetics provides an up-to-date review of the area, suitable for clinicians treating stroke patients, and both clinical and non-clinical researchers in the field of cerebrovascular disease. The full range of monogenic stroke disorders causing cerebrovascular disease, including ischaemicstroke, intracerebral haemorrhage, aneurysms and arteriovenous malformations, are covered. For each, clinical features, diagnosis, and genetics are described. Increasing evidence suggest that genetic factors are also important for the much more common multifactorial stroke; this evidence isreviewed along with the results of genetic studies in this area. Optimal and novel strategies for investigating multifactorial stroke, including the use of intermediate phenotypes such as intima-media thickness and MRI detected small vessel disease are reviewed. The book concludes by describing apractical approach to investigating patients with stroke for underlying genetic disorders. Also included is a list of useful websites.
Download or read book Atherosclerosis 4 written by Fujio Numano and published by . This book was released on 1997 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Atlas of Atherosclerosis and Metabolic Syndrome written by Scott M. Grundy and published by Springer Science & Business Media. This book was released on 2011-03-14 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition is an integral source of information on Atherosclerosis. It covers topics such as newer coronary risk factors, high-density lipoprotein metabolism, lipid-lowering drugs, endothelium and thrombosis in atherogenesis, and contributing risk factors. With over 500 exceptional photographs, diagrams, and charts, each chapter illustrates an important facet of diagnosing and treating this common and often fatal disease.
Download or read book Inflammation and Atherosclerosis written by Georg Wick and published by Springer Science & Business Media. This book was released on 2011-12-03 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has been known for over 150 years that hallmarks of inflammation can be observed in the wall of atherosclerotic vessels. It was, however, not clear if this inflammation is the cause or the consequence of atherogenesis. More recently, it has become evident that inflammation mediated both by innate and adaptive immunity is instrumental even in the earliest stages of the development of atherosclerotic lesions, i.e., that it plays an important pathogenetic role. In this volume, international experts in the field discuss the pathogenetic, diagnostic, preventive and possible therapeutic relevance of inflammation in atherogenesis. This book is intended for researchers and physicians in the fields of vascular biology, immunology and atherosclerosis.
Download or read book Inflammatory Atherosclerosis written by Richard James Frink and published by Heart Research Foundation Sacrament. This book was released on 2002 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Atherosclerosis and Its Origin written by Maurice Sandler and published by . This book was released on 1963 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Atherosclerosis Diet and Drugs written by Arnold Eckardstein and published by Springer Science & Business Media. This book was released on 2005-11-02 with total page 808 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular diseases continue to be the leading cause of death in the - jority of industrialized countries. The most frequent underlying pathology, namely atherosclerosis, and its clinical sequelae, namely coronary heart d- ease, cerebrovascular disease and peripheral artery disease, remain common although for a long time we have been made aware of avoidable or mo- ?able etiological factors such as smoking, fat-rich diet or lack of exercise, and although these adverse lifestyle factors have been extensively addressed by population-wide primary prevention programs. Cardiovascular morbidity and mortality also remain high despite successful anti-hypertensive and lipid lowering drug therapies which help to reduce cardiovascular morbidity and mortality by about 30% in both secondary and tertiary prevention settings. This can partly be explained by the increasing life expectancy and growing p- portionofelderly people,especiallyinEuropeandNorthAmerica. Inaddition, the World Health Organization makes the alarming prediction that probably in response to the spreading of western dietary behavior and lack of exercise resulting in an increasing prevalence of diabetes, dyslipidemia and hypert- sion, cardiovascular diseases rather than infectious diseases will become the most frequent cause of death worldwide. This volume of the Handbook of Experimental Pharmacology entitled “Atherosclerosis” is divided into four parts and intends to give an overview on the pathogenesis of atherosclerosis, established treatment and prevention regimen, and of perspectives for the development of new treatment modalities.
Download or read book Atherosclerosis written by G. Manning and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Workshop - Conference on Atherosclerosis was held at the University of Western Ontario, London, Ontario, Canada, September 1 - 3, 1975. This book does not represent in a strict sense the entire proceedings of the above Workshop - Conference, but does reflect largely the format and the essential content of the scientific sessions. Thus, each of the three Sections of the book is comprised of the summarized presentations either at the Plenary Sessions (Section I), Proffered Papers (Section II) or Workshops (Section III). Section I comprises all the presentations of the Plenary Session on September 1 and the first three presentations at the Plenary Session on the last day of the Conference (September 3). The remaining two addresses of the latter Session (Resume of Workshop - Conference and Closing Remarks) follow the Section III at the end of the book. Sections II and III are subdivided into Chapters which correspond to the individual Sessions of Proffered Papers and Workshops, respectively. To facilitate the orientation, particularly for those who attended the Workshop - Conference, a Summary Table of all Sessions of Proffered Papers designated as Chapters in this book, precedes Section II, and a similar Summary Table of Workshops, also designated as Chapters, precedes Section III. The Tables include, in addition, the names of both Chairmen of each Session. The Chairmen whose names do not appear on either Summary Table are those who chaired the two Plenary Sessions, i. e.
Download or read book Expanding Horizons in Atherosclerosis Research written by Günter Schlierf and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 625 pages. Available in PDF, EPUB and Kindle. Book excerpt: On 29 February 1964, a group of European scientists met in Paris to discuss a subject of common interest, namely atherosclerosis research, with particular reference to international communication and collaboration. After a second meeting on 15 May 1964, they founded the European Atherosclerosis Group which was to com prise individuals engaged in the various disciplines of atherosclero sis research in Eastern and Western Europe. Since then this group has initiated multidisciplinary discussion and scientific collabora tion across Europe, in accordance with the objects and aims written in its statutes: 1. To hold colloquia and symposia dealing with research in the field of atherosclerosis and allied sciences 2. To encourage meetings and exchanges between scientists in the group engaged in the investigation of atherosclerosis 3. To encourage collaborative work between national and interna tional centers engaged in atherosclerosis research 4. To encourage the publication of reviews, etc. , on atherosclerosis research which may be considered of value 5. To promote research fellowships, particularly for younger research workers, for studies within the field of atherosclerosis and allied sciences 6. To accept dues, endowments, grants, funds, and bequests to be used for the above purposes The European Atherosclerosis Group has helped to bring together what was separated during the second world war and the postwar period in Europe and to reestablish ties with the leading American teams.
Download or read book Early Vascular Aging EVA written by Pedro Guimarães Cunha and published by Elsevier. This book was released on 2024-02-29 with total page 772 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early Vascular Aging (EVA): New Directions in Cardiovascular Protection, Second Edition continues to be the most comprehensive and authoritative resource on premature alterations in artery structure and function. The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. This second edition contains completely updated content with expanded coverage of basic and translational research, systematic reviews of the most prominent literature, discussion of applicability of new evidence and more. Written by an international team of clinicians and researchers, this is a valuable resource to basic and translational scientists, clinical researchers and clinicians in the cardiovascular field interested in prevention, diagnosis and treatment of EVA. - Contains all the relevant information available on the main paradigm shifts in vascular aging research, from different fields of knowledge (from basic biology to epidemiology) - Reviews the most prominent evidence produced on early vascular aging (EVA), highlighting recent research advances, clinical applications, and research opportunities - Formulates, in each chapter, a set of research questions that need to be addressed, challenging the vast research community to take on new directions and collaborations
Download or read book Atherosclerosis written by Dipak Ramji and published by Humana. This book was released on 2023-03-18 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides detailed, up-to-date methods used in research on Atherosclerosis. Chapters guide readers through an overview of the pathogenesis of atherosclerosis and model systems together with in vitro, ex vivo, in vivo and emerging methods in atherosclerosis research. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Atherosclerosis: Methods and Protocols serves as an invaluable resource for those engaging in research on atherosclerosis and cardiovascular disease, as well as for researchers who are new to the field and students at both the undergraduate and postgraduate level.
