Download or read book Asthma written by Mark A. Giembycz and published by . This book was released on 2000 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Asthma written by M. A. Giembycz and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Asthma Epidemiology Anti Inflammatory Therapy and Future Trends written by Mark A. Giembycz and published by Springer. This book was released on 2012-12-06 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. 1. Invasive versus Non-Invasive Clinical Measurements in Medicine Clinical measurement has become an essential complement to traditional physical diagnosis. An ideal clinical measurement should be quantitative, have a high level of reliability and accuracy, be safe, acceptable to the patient, easy to perform and non-invasive. The latter demands that the technique should not break the skin or the lining epithelium and should be devoid of effects on the tissues of the body by the dissipation of energy or the introduction of infection [1]. It is therefore logical that for a given measurement, a non-invasive test will be preferred if it provides the same information with the same accuracy and precision. In the following sections, we will discuss the role of various non-invasive or relatively non-invasive methods to assess airway inflammation in asthma and concentrate on the only direct method of induced sputum examination. 1. 2. Why Is Assessment of Airway Inflammation Important in Asthma? Inflammation is a localized protective response elicited by injury or destruc tion of tissues which serves to destroy, dilute or wall off both the injurious agent and the injured tissue [2]. The role of inflammation in asthma was rec ognized long ago. In his textbook The Principles and Practice of Medicine, in 1892, Sir William Osler described "bronchial asthma . . . in many cases is a spe cial form of inflammation of the smaller bronchioles . . .
Download or read book New and Exploratory Therapeutic Agents for Asthma written by Michael Yeadon and published by CRC Press. This book was released on 1999-11-12 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses three major classes of asthma therapies-bronchodilators, antiinflammatories, and antiallergics-as well as potential new therapeutic approaches! This comprehensive volume addresses the latest treatment strategies for asthma, keying in on the genetics and molecular biology of asthma and pointing the way toward new, commercially viable therapies. Presents the most up-to-date information available on the genetics, epidemiology, pathology, pharmacology, and pulmonology of asthma. Written by more than 20 leading international experts, New and Exploratory Therapeutic Agents for Asthma explores asthma both as incidence of dysfunctional airway smooth muscle and as a disorder of the immune system examines the role of monoclonal antibodies in allergy and asthma describes functions and pharmacokinetic profiles of bronchodilator 2 agonists, anticholinergics, and inhaled glucocorticosteroids investigates the controversy of different types of asthma illustrates the connections between clinical symptoms and the immunopathology of eosinophilic inflammation assesses prospects for the development of a successful oral anti-inflammatory therapy, an immunomodulator that lowers antigen-specific IgE, an anticytokine compound, and an agent that safely combines bronchospasmolytic and anti-inflammatory properties reviews the impact of the recent introduction of antileukotriene agents, clinical findings with PAF antagonists, and selective antimuscarinics evaluates the relationship between improvements in laboratory results and clinical effectiveness and more! Containing over 2000 bibliographic citations and a concise introduction for each chapter, New and Exploratory Therapeutic Agents for Asthma is indispensable for pulmonologists, pediatricians, physiologists, immunologists, allergists, pharmaceutical industry scientists, primary care physicians, and medical school students in these disciplines.
Download or read book Severe Asthma written by Kian Fan Chung and published by European Respiratory Society. This book was released on 2019-06-01 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with greatest unmet needs. In the last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma; there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
Download or read book Allergy Frontiers Epigenetics Allergens and Risk Factors written by Ruby Pawankar and published by Springer Science & Business Media. This book was released on 2008-12-05 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume. Compare this with Allergy Frontiers: Epigenetics, Allergens, and Risk Factors, the present s- volume text with well over 150 contributors from throughout the world. This book captures the explosive growth of our specialty since the single-author textbooks referred to above. The unprecedented format of this work lies in its meticulous attention to detail yet comprehensive scope. For example, great detail is seen in manuscripts dealing with topics such as “Exosomes, naturally occurring minimal antigen presenting units” and “Neuropeptide S receptor 1 (NPSR1), an asthma susceptibility gene.” The scope is exemplified by the unique approach to disease entities normally dealt with in a single chapter in most texts. For example, anaphylaxis, a topic usually confined to one chapter in most textbooks, is given five chapters in Allergy Frontiers. This approach allows the text to employ multiple contributors for a single topic, giving the reader the advantage of being introduced to more than one vi- point regarding a single disease.
Download or read book GIS for Health and the Environment written by Poh C. Lai and published by Springer Science & Business Media. This book was released on 2007-10-04 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aimed at all types of public health practitioners and theorists, this book is a compilation of methodological and application developments in spatial epidemiological approaches for environmental and public health studies in the Asia Pacific region. It aims to plug a gap in the literature that has seen a shortage of materials documenting the development of health GIS in this crucial part of the world.
Download or read book Gastrointestinal Physiology written by Menizibeya Osain Welcome and published by Springer. This book was released on 2018-06-20 with total page 1028 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers’ understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special “clinical correlates” sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.
Download or read book Traffic Related Air Pollution written by Haneen Khreis and published by Elsevier. This book was released on 2020-08-20 with total page 650 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traffic-Related Air Pollution synthesizes and maps TRAP and its impact on human health at the individual and population level. The book analyzes mitigating standards and regulations with a focus on cities. It provides the methods and tools for assessing and quantifying the associated road traffic emissions, air pollution, exposure and population-based health impacts, while also illuminating the mechanisms underlying health impacts through clinical and toxicological research. Real-world implications are set alongside policy options, emerging technologies and best practices. Finally, the book recommends ways to influence discourse and policy to better account for the health impacts of TRAP and its societal costs. Overviews existing and emerging tools to assess TRAP’s public health impacts Examines TRAP’s health effects at the population level Explores the latest technologies and policies--alongside their potential effectiveness and adverse consequences--for mitigating TRAP Guides on how methods and tools can leverage teaching, practice and policymaking to ameliorate TRAP and its effects
Download or read book Memoirs of the Scientific Sections of the Academy of the Socialist Republic of Romania written by and published by . This book was released on 2003 with total page 1062 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Middleton s Allergy Essentials E Book written by Robyn E. O'Hehir and published by Elsevier Health Sciences. This book was released on 2015-12-09 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: For decades, health care practitioners have relied on Middleton’s Allergy as their go-to reference for comprehensive information on allergic disorders. Now Middleton’s Allergy Essentials, by Drs. Robyn E. O'Hehir, Stephen T. Holgate, and Aziz Sheikh, offers a concise resource that’s both easily accessible and highly authoritative. Perfect for clinicians in primary and secondary care settings, this practical volume covers what is most useful in your daily practice, with a strong emphasis on disease diagnosis and management. A practical approach to evaluation, differential diagnosis, and treatment of allergic disorders, focused specifically on what the non-specialist needs to know for everyday practice. Each chapter begins with a handy summary of key concepts to help you quickly identify important information. Coverage of today’s hot topics includes asthma, drug allergies, food allergies and gastrointestinal disorders, anaphylaxis, atopic dermatitis, and allergic contact dermatitis. Concise sections on mechanisms are included where relevant, keeping you up to date with this rapidly evolving field. Authored by the same internationally recognized experts that produce Middleton’s Allergy, the definitive text in the field. Ideal for physicians, residents, general and family practitioners, nurse practitioners, primary care doctors, hospitalists, general internists – anyone who is called upon to make effective diagnostic and treatment decisions regarding allergic disorders.
Download or read book Chest Medicine written by Ronald B. George and published by Lippincott Williams & Wilkins. This book was released on 2005 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: A favorite among residents and pulmonary fellows, this text provides all the information needed to evaluate and manage respiratory diseases and critically ill patients and to pass the American Board of Internal Medicine's subspecialty exam in pulmonary medicine. The Fifth Edition includes new information on ARDS, sedation of critically ill patients, rehabilitation for COPD, care of elderly patients, genetic testing for asthma, CTA and other diagnostic techniques for pulmonary thromboembolism, new antifungal drugs without renal toxicity, new treatment guidelines for pneumothorax, and ventilators and noninvasive ventilation for respiratory failure. This edition also includes more algorithms and differential diagnosis tables.
Download or read book New and Exploratory Therapeutic Agents for Asthma written by Michael Yeadon, PH.D. and published by CRC Press. This book was released on 2019-08-30 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses three major classes of asthma therapies-bronchodilators, antiinflammatories, and antiallergics-as well as potential new therapeutic approaches This comprehensive volume addresses the latest treatment strategies for asthma, keying in on the genetics and molecular biology of asthma and pointing the way toward new, commercially viable therapies. Presents the most up-to-date information available on the genetics, epidemiology, pathology, pharmacology, and pulmonology of asthma. Written by more than 20 leading international experts, New and Exploratory Therapeutic Agents for Asthma explores asthma both as incidence of dysfunctional airway smooth muscle and as a disorder of the immune system examines the role of monoclonal antibodies in allergy and asthma describes functions and pharmacokinetic profiles of bronchodilator 2 agonists, anticholinergics, and inhaled glucocorticosteroids investigates the controversy of different types of asthma illustrates the connections between clinical symptoms and the immunopathology of eosinophilic inflammation assesses prospects for the development of a successful oral anti-inflammatory therapy, an immunomodulator that lowers antigen-specific IgE, an anticytokine compound, and an agent that safely combines bronchospasmolytic and anti-inflammatory properties reviews the impact of the recent introduction of antileukotriene agents, clinical findings with PAF antagonists, and selective antimuscarinics evaluates the relationship between improvements in laboratory results and clinical effectiveness and more Containing over 2000 bibliographic citations and a concise introduction for each chapter, New and Exploratory Therapeutic Agents for Asthma is indispensable for pulmonologists, pediatricians, physiologists, immunologists, allergists, pharmaceutical industry scientists, primary care physicians, and medical school students in these disciplines.
Download or read book Current Clinical Medicine E Book written by Cleveland Clinic and published by Elsevier Health Sciences. This book was released on 2010-08-13 with total page 1568 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current Clinical Medicine's 2nd edition, by the world famous Cleveland Clinic, is an Internal Medicine reference that gives you authoritative and actionable information wherever you are, whenever you need it. More than 40 updated chapters, 13 new chapters, and 30% new illustrations ensure that you’ll have access to the most up-to-date guidance. In addition to its user-friendly, easy-access format and consistent, reliable coverage, this Expert Consult title includes a website with the complete contents of the book, fully searchable, downloadable images, and more, to keep you and your practice completely current. Includes access to a website featuring the complete contents of the book, fully searchable, access to patient information sheets, links to the Gold Standard Drug database, and much more, to keep you completely current. Provides consistent, reliable coverage to keep you on the top of your game. Includes summary boxes and algorithms for quick, confident diagnosis and treatment of each condition. Features a user-friendly format so you can find information quickly and easily. Contains more than a hundred full-color illustrations with a special focus on dermatology for highly visual guidance. Uses evidence-based gradings to help you evaluate your diagnoses. Includes many new chapters—including Hepatocellular Carcinoma, Head and Neck Cancer, Takayasu's Arteritis, and Non-Hodgkin and Hodgkin Lymphoma—as well as more than 40 substantially revised chapters, that ensure that you’ll have access to the most current coverage. Features 30% new illustrations that provide you with updated details, concepts, and procedures.
Download or read book Personalizing Asthma Management for the Clinician written by Stanley J. Szefler and published by Elsevier Health Sciences. This book was released on 2017-09-22 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized medicine is a rapidly emerging area in health care, and asthma management lends itself particularly well to this new development. This practical resource by Dr. Stanley J. Szefler helps you navigate the many asthma medication options available to your patients, as well as providing insights into those which may be introduced within the next several years. Features a wealth of information on available asthma medications, including new immunomodulators, new responses to treatment, and new treatment strategies at all levels of asthma care. Prepares you to meet your patients’ needs regarding asthma exacerbation prevention and asthma prevention. Consolidates today’s available information and guidance in this timely area into one convenient resource.
Download or read book Paediatric Asthma written by Kai-Håkon Carlsen and published by European Respiratory Society. This book was released on 2012-06-01 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a disease of many faces and is frequently seen in children. This Monograph covers all aspects of paediatric asthma, across all ages, from birth through to the start of adulthood. It considers diagnostic problems in relation to the many phenotypes of asthma, covers the treatment of both mild-to-moderate and severe asthma, and discusses asthma exacerbations as well as exercise-induced asthma. The issue also provides an update on the pathophysiology of asthma, the role of bacterial and viral infections, and the impact of environmental factors, allergy, genetics and epigenetics. Finally,
Download or read book Asthma Pathophysiology Herbal and Modern Therapeutic Interventions written by Sheikh Rayees and published by Springer Nature. This book was released on 2021-03-26 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: Asthma is a chronic airway disease affecting over 300 million people worldwide with an expected increase of an additional 100 million by 2025. Past decade has observed a notable increase in asthma prevalence on both national and global levels with highest rates observed in western countries (about 30%). Over the past 40 years, a drastic increase in global prevalence, morbidity, mortality, and economic burden have been observed due to asthma especially in children. The rising numbers of hospital admissions for asthma, especially young children, reflect an increase in severe asthma, poverty and lack of proper disease management. Worldwide, approximately 180,000 deaths annually are caused due to this condition. The financial burden on a single asthma patient per year in different western countries ranges from US$300–1,300. Asthma is an intricate respiratory disorder with differences in its severity, natural history and hence treatment response. These differences in intensities of various presentations such as bronchial hyper-responsiveness, airway inflammation, mucus production, airflow obstruction make asthma a heterogeneous disease. The mainstay of current therapies for asthma includes inhaled corticosteroids, phosphodiesterase inhibitors, leukotriene modifiers and β2-adrenoceptor agonists. Some of the currently available drugs are efficient in one or more aspects. However the associated side effects or heterogeneity of the disease limit their usefulness and efficacy, thereby putting a demand on development of new drugs and therapies. On the other hand, asthma has also been treated/managed via herbal medications. These approaches have been described in Unani, Ayurvedic or Chinese system of medicine since antiquity. In fact, several anti-asthmatic drugs were developed from herbs commonly utilized in the non-Western system of medicine. This book focuses on the pathophysiology of asthma, its medication (both herbal and modern), limitations and their future prospects.
