Download or read book Chirality in Drug Research written by Eric Francotte and published by John Wiley & Sons. This book was released on 2007-09-24 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, including large-scale synthesis and purification of chirally pure pharmaceuticals. The two editors from academia and a major pharmaceutical company have assembled an experienced, international team who provide first-hand practical advice and report previously unpublished data. In the first section, the isolation of chiral drugs from natural sources, their production in enzymatic processes and the resolution of racemic mixtures in preparative chromatography are outlined in separate chapters. For the section on qualitative and quantitative analysis, enantioselective chromatographic methods are presented as well as optical methods and CE-MS, while the final section deals with the pharmacology, pharmacokinetics and metabolic aspects of chiral drugs, devoting whole chapters to stereoselective drug binding and modeling chiral drug-receptor interactions. With its unique industry-relevant aspects, this is a must for medicinal and pharmaceutical chemists.
Download or read book Engineering Applications for New Materials and Technologies written by Andreas Öchsner and published by Springer. This book was released on 2018-01-25 with total page 645 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the expertise, skills, and techniques needed for the development of new materials and technologies. It focuses on finite element and finite volume methods that are used for engineering simulations, and present many state-of-the-art applications and advances to highlight these methods’ importance. For example, modern joining technologies can be used to fabricate new compound or composite materials, even those formed from dissimilar component materials. These composite materials are often exposed to harsh environments, must deliver specific characteristics, and are primarily used in automotive and marine technologies, i.e., ships, amphibious vehicles, docks, offshore structures, and even robots. To achieve the desired material performance, computer-based engineering tools are widely used for simulation, data evaluation, and design processes.
Download or read book Signs of Life in the U S A written by Sonia Maasik and published by St. Martin's Press. This book was released on 1997 with total page 824 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Making a Living in Your Local Music Market written by Dick Weissman and published by Hal Leonard Corporation. This book was released on 2006 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: You can survive happily as a musician in your local music market. This book shows you how to expand and develop your skills as a musician and a composer right in your own backyard. Making a Living in Your Local Music Market explores topics relevant to musicians of every level: Why should a band have an agreement? How can you determine whether a personal manager is right for you? Are contests worth entering? What trade papers are the most useful? Why copyright your songs? Also covers: * Developing and packaging your artistic skills in the marketplace * Dealing with contractors, unions, club owners, agents, etc. * Producing your own recordings * Planning your future in music * Music and the Internet * Artist-operated record companies * The advantages and disadvantages of independent and major record labels * Grant opportunities for musicians and how to access them * College music business programs * Seminars and trade shows * Detailed coverage of regional music markets, including Austin, Atlanta, Denver, Miami, Seattle, and Portland, Oregon.
Download or read book Zebrafish Protocols for Neurobehavioral Research written by Allan V. Kalueff and published by Humana Press. This book was released on 2012-06-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Zebrafish (Danio rerio) play an integral role in biomedical research, enabling researchers to examine physiological mechanisms and pathways relevant to human pathogenesis and its therapy. That, along with their low cost, easy manipulation, short reproductive cycles, and physiological homology to humans, has made zebrafish a vital model organism for neuroscience research. Zebrafish Protocols for Neurobehavioral Research addresses protocols for both larval and adult models, written by the leading experts in the field of zebrafish research. Part I of this book takes advantage of the high-throughput nature of larval models to offer protocols for research requiring high output, easily manipulated screens. The second half of the book focuses on the robust and sophisticated behaviors of adult zebrafish, suitable for the neurophenotyping of complex traits and multi-domain disorders. Importantly, these models complement each other, working together to provide researchers with valuable insights into neurobiology of normal and pathological behavior. Thorough and cutting-edge, this volume is a useful, authoritative reference guide that should hold a coveted spot in zebrafish laboratories across the globe.
Download or read book The Scott Chronicles written by Bob Wingate and published by . This book was released on 2020-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Value of Hawai i written by Craig Howes and published by University of Hawaii Press. This book was released on 2010-07-02 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: How did we get here? Three-and-a-half-day school weeks. Prisoners farmed out to the mainland. Tent camps for the migratory homeless. A blinkered dependence on tourism and the military for virtually all economic activity. The steady degradation of already degraded land. Contempt for anyone employed in education, health, and social service. An almost theological belief in the evil of taxes. At a time when new leaders will be elected, and new solutions need to be found, the contributors to The Value of Hawai‘i outline the causes of our current state and offer points of departure for a Hawai‘i-wide debate on our future. The brief essays address a wide range of topics—education, the environment, Hawaiian issues, media, tourism, political culture, law, labor, economic planning, government, transportation, poverty—but the contributors share a belief that taking stock of where we are right now, what we need to change, and what we need to remember is a challenge that all of us must meet. Written for a general audience, The Value of Hawai‘i provides a cluster of starting points for a larger community discussion of Hawai‘i that should extend beyond the choices of the ballot box this year. Contributors: Carlos Andrade, Chad Blair, Kat Brady, Susan M. Chandler, Meda Chesney-Lind, Lowell Chun-Hoon, Tom Coffman, Sara L. Collins, Marilyn Cristofori, Henry Curtis, Kathy E. Ferguson, Chip Fletcher, Dana Naone Hall, Susan Hippensteele, Craig Howes, Karl Kim, Sumner La Croix, Ian Lind, Melody Kapilialoha MacKenzie, Mari Matsuda, Davianna McGregor, Neal Milner, Deane Neubauer, Jonathan Kay Kamakawiwo’ole Osorio, Charles Reppun, John P. Rosa, D. Kapua‘ala Sproat, Ramsay Remigius Mahealani Taum, Patricia Tummons, Phyllis Turnbull, Trisha Kehaulani Watson.
Download or read book Hidden Americans written by Hugo Prosper Leaming and published by Routledge. This book was released on 1995-01-01 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1995. Routledge is an imprint of Taylor & Francis, an informa company.
Download or read book Confinement and Ethnicity written by Jeffery F. Burton and published by University of Washington Press. This book was released on 2011-07-01 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Confinement and Ethnicity documents in unprecedented detail the various facilities in which persons of Japanese descent living in the western United States were confined during World War II: the fifteen “assembly centers” run by the U.S. Army’s Wartime Civil Control Administration, the ten “relocation centers” created by the War Relocation Authority, and the internment camps, penitentiaries, and other sites under the jurisdiction of the Justice and War Departments. Originally published as a report of the Western Archeological and Conservation Center of the National Park Service, it is now reissued in a corrected edition, with a new Foreword by Tetsuden Kashima, associate professor of American ethnic studies at the University of Washington. Based on archival research, field visits, and interviews with former residents, Confinement and Ethnicity provides an overview of the architectural remnants, archeological features, and artifacts remaining at the various sites. Included are numerous maps, diagrams, charts, and photographs. Historic images of the sites and their inhabitants -- including several by Dorothea Lange and Ansel Adams -- are combined with photographs of present-day settings, showing concrete foundations, fence posts, inmate-constructed drainage ditches, and foundations and parts of buildings, as well as inscriptions in Japanese and English written or scratched on walls and rocks. The result is a unique and poignant treasure house of information for former residents and their descendants, for Asian American and World War II historians, and for anyone interested in the facts about what the authors call these “sites of shame.”
Download or read book An Introduction to Human Geography written by Peter Daniels and published by Pearson Higher Ed. This book was released on 2016-05-05 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fifth edition of this widely used text provides a global overview of the major topics within human geography, including food security and population, geopolitics and territory, inequality and power, production, consumption, the global financial system, governance and now a new chapter on citizenship. Substantial and comprehensively updated chapters ensure balanced treatment across the range of contemporary human geography.
Download or read book The Hegemony of Heritage written by Deborah L. Stein and published by Univ of California Press. This book was released on 2018-05-11 with total page 338 pages. Available in PDF, EPUB and Kindle. Book excerpt: A free ebook version of this title is available through Luminos, University of California Press’s Open Access publishing program. Visit www.luminosoa.org to learn more. The Hegemony of Heritage makes an original and significant contribution to our understanding of how the relationship of architectural objects and societies to the built environment changes over time. Studying two surviving medieval monuments in southern Rajasthan—the Ambika Temple in Jagat and the Ékalingji Temple Complex in Kailaspuri—the author looks beyond their divergent sectarian affiliations and patronage structures to underscore many aspects of common practice. This book offers new and extremely valuable insights into these important monuments, illuminating the entangled politics of antiquity and revealing whether a monument’s ritual record is affirmed as continuous and hence hoary or dismissed as discontinuous or reinvented through various strategies. The Hegemony of Heritage enriches theoretical constructs with ethnographic description and asks us to reexamine notions such as archive and text through the filter of sculpture and mantra.
Download or read book What the Scarecrow Said written by Stewart D. Ikeda and published by Regan Books. This book was released on 1996-06-05 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt: In World War II, two spirited widows obtain the release of a California horticulturist from an internment camp for Japanese-Americans in the hope that he will turn their barren land in Massachusetts into a farm. The man, a widower himself, becomes a reluctant participant in an impromptu family.
Download or read book Ifism written by Cromwell Osamaro Ibiè and published by . This book was released on 1986 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Anion Sensing written by Ivan Stibor and published by Springer. This book was released on 2014-11-21 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: with contributions by numerous experts
Download or read book Seventeen Syllables written by Hisaye Yamamoto and published by Rutgers University Press. This book was released on 1994 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: On the surface, "Seventeen Syllables" is the story of Rosie and her preoccupation with adolescent life. Between the lines, however, lurks the tragedy of her mother, who is trapped in a marriage of desperation.
Download or read book Asia Pacific Defense Forum written by and published by . This book was released on with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book China and India written by Mohan Malik and published by Firstforumpress. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite burgeoning trade and cultural links, China and India remain fierce competitors in a world of global economic rebalancing, power shifts, resource scarcity, environmental degradation, and other transnational security threats. Mohan Malik explores this increasingly important and complex relationship, grounding his analysis in the history of the two countries. Malik describes a geopolitical rivalry underpinned by contrasting systems, values, and visions. His comparative analysis covers the broad spectrum of challenges that China and India face. Drawing on his extensive research and on-the-ground experience, he concludes with a discussion of alternative strategic futures for Sino-Indian relations.
