Download or read book Application of Plant Secondary Metabolites to Pain Neuromodulation written by Adriana Gibara Guimarães and published by Frontiers Media SA. This book was released on 2021-02-11 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Application of Plant Secondary Metabolites to Pain Neuromodulation Volume II written by Adriana Gibara Guimarães and published by Frontiers Media SA. This book was released on 2024-11-11 with total page 129 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of natural products and their metabolites in the treatment of pain and other diseases has been recognized by contemporary science, and a range of medications currently used in the clinic were indeed initially developed from natural products including medicinal plants. Historically, the mark of obtaining bioactive compounds with analgesic potential occurred in the 19th century when the first analgesic drugs obtained from medicinal plants were marketed. These included especially the opioids, such as morphine extracted from papaver (Papaver somniferum) and acetylsalicylic acid, which was synthesized from salicylic acid extracted from willow bark (Salix spp.). After almost two centuries, new analgesic compounds have been extracted from natural products, for example capsaicin obtained from pepper (Capsicum annuum), the peptide ziconotide extracted from the marine mollusc Conus magus, and cannabinoid compounds extracted from Cannabis sativa (tetrahydrocannabinol, cannabidiol and others). In addition to the diversity of their chemical constituents, natural products have a range of pharmacological targets that make them potent analgesic compounds. In fact, a large part of these compounds is able to promote the modulation of several neurotransmission systems, such as opioid, cannabinoid and purinergic, as well as voltage-sensitive ion channels including transient receptor potential (TRP) channels and acid-sensing ion channels (ASICs). Besides, these compounds are normally important modulators of inflammatory mediators release and redox imbalance. Even in case of rheumatoid arthritis, neuropathy, focus on the redox imbalance as well as hyaluronidase inhibition are also the important factors, which are being considered by the researchers worldwide. In this context, natural products like nuciferoic acid plays a very important role in controlling hyaluronidase enzyme.
Download or read book Application of Plant Secondary Metabolites to Pain Neuromodulation Volume II written by Liangming Pan and published by Frontiers Media SA. This book was released on 2022-11-08 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Diagnostics and Treatment of Functional Neurological Disorders Neurogenomics Neuromodulation and Machine Learning written by Guohui Lu and published by Frontiers Media SA. This book was released on 2022-11-03 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Trends in Food Chemistry Nutrition and Technology in Indian Sub Continent written by Suni Mary Varghese and published by Springer Nature. This book was released on 2022-07-05 with total page 73 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brief outlines the state-of-art of the food industry within the Indian Sub-continent, providing a detailed insight into the current science of nutrition and industrial technology. The Hygiene, Integrity, Traceability and Sharing (HITS) strategy has been proposed recently as a coordinated and powerful tool to contextualize the plethora of different menaces for the food consumer. The book examines this approach from eight different perspectives, with a particular emphasis on the Indian Subcontinent. Topics such as food additives, the importance of water in the food industry, the use of antioxidants, and novel food preservation methods are used to illustrate these points of view. This book is particularly appealing as a guide for graduate and undergraduate courses covering food production, food safety, and the training of teachers working in these science areas.
Download or read book Exploration of Natural Product Leads for Multitarget Based Treatment of Cancer Computational to Experimental Journey written by Rajeev K. Singla and published by Frontiers Media SA. This book was released on 2022-03-14 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neuromodulation written by and published by Academic Press. This book was released on 2009-05-05 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices. All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come.Key Features - The first comprehensive reference on the emerging field of Neuromodulation - Editors and authors include all leading figures in the field, and the leaders of the International Neuromodulation Society - Over 90 chapters on topics ranging from a layout of the fundamentals (e.g. neuroanatomy, plasticity, bioelectrical effects, infusion therapies), solutions for the biomedical engineering challenges (e.g. materials, how to preserve normal function etc.), to a rundown of the existing applications and their future promise - Over 1200 pages in splendid full color, richly illustrated - Important areas of application include: control of chronic pain delivery of drugs to the nervous system via implanted devices control of epilepsy, Parkinson, etc. functional restoration, e.g. visual, auditory, restoration after stroke, restoration of motor function after traumatic events stimulation of body organs via neural devices (incl. the heart, abdominal organs, genitourinary organs) overview over newly emerging fields - control of obesity, blood pressure, tinnitus, brain injury, neurodegenerative diseases, brain-machine interfaces
Download or read book Phytocannabinoids written by A. Douglas Kinghorn and published by Springer. This book was released on 2017-01-24 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book presents the current state of the art on phytocannnabinoid chemistry and pharmacology and will be of much use to those wishing to understand the current landscape of the exciting and intriguing phytocannabinoid science. The focus is on natural product cannabinoids which have been demonstrated to act at specific receptor targets in the CNS.
Download or read book Voltage Gated Sodium Channels written by Peter C. Ruben and published by Springer Science & Business Media. This book was released on 2014-04-15 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.
Download or read book Case Studies in Pain Management written by Alan David Kaye and published by Cambridge University Press. This book was released on 2014-10-16 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by internationally recognized pain experts, this book offers 73 clinically relevant cases, accompanied by discussion in a question-and-answer format.
Download or read book Drug Repurposing in Neurodegenerative and Neuropsychiatric Disorders written by Anna R. Carta and published by Frontiers Media SA. This book was released on 2022-01-25 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Geriatric Forensic Psychiatry written by Jacob Holzer and published by Oxford University Press. This book was released on 2017-12-12 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook, one of the first, provides a comprehensive review of the relationship between psychiatry and legal medicine in the older population. Sections reviewing evaluation, civil and criminal topics, and numerous other areas such as risk management, will help physicians, attorneys, and other professionals in their work with the elderly.
Download or read book Treatment resistant Mood Disorders written by Andre Carvalho and published by Oxford University Press, USA. This book was released on 2015 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: Treatment-resistant major depression and bipolar disorder are highly prevalent and disabling conditions associated with substantial morbidity and mortality. Providing a concise view of the current definitions, assessment and evidence-based management of such disorders, this work reviews novel therapeutic targets, which may enhance the future therapeutic armamentarium of clinicians.
Download or read book Transcutaneous Electrical Nerve Stimulation TENS written by Mark I. Johnson and published by OUP Oxford. This book was released on 2014-03-06 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transcutaneous electrical nerve stimulation (TENS) is a technique that delivers mild electrical currents across the intact surface of the skin to reduce pain. TENS is used by practitioners throughout the world to manage painful conditions and TENS equipment can be purchased by the general public so that they can self-administer treatment. There are thousands of experimental and clinical research studies published on TENS and related techniques yet there is uncertainty about the best way to administer TENS in clinical practice. This is because currents used during TENS can be administered in a variety of ways and the findings of research studies have been inconclusive. This book provides guidance on how best to use TENS based on an evaluation of current research evidence. The book covers what TENS is, how it works, and safe and appropriate clinical techniques for many conditions including chronic low back pain, osteoarthritis and cancer pain. It also offers solutions to the problems faced by researchers when trying to design clinical trials on TENS. Accessibility written, Transcutaneous Electrical Nerve Stimulation (TENS) provides a comprehensive coverage of research issues and findings about TENS and will be essential reading for healthcare professionals, practitioners and students.
Download or read book Pain Imaging written by Maria Assunta Cova and published by Springer. This book was released on 2019-03-06 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses all pain imaging aspects related to both the central nervous system and the body (thorax, abdomen and pelvis), thus updating the international literature on the topic. By adopting a clinical-radiological approach and offering a comprehensive differential diagnosis for a number of painful syndromes (many of which can mimic one other), the work aims to support and enhance the diagnostic management of these patients, suggesting the most appropriate diagnostic algorithm. The book is divided into separate sections for each anatomical macro-area, and the chapters cover the respective topics from both clinical and radiological perspectives. Further, the book includes extensive electronic supplementary material. As such, it offers an invaluable tool for radiologists, neuroradiologists and clinicians working in internal medicine, surgery and neurology, and could also be used in residency programs for these groups.
Download or read book Problem Based Pain Management written by Eric S. Hsu and published by Cambridge University Press. This book was released on 2013-10-24 with total page 398 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pain management is an essential part of clinical practice for all healthcare providers from trainees, physician assistants and nurse practitioners through to practising physicians. Problem-Based Pain Management is a collaboration between experts in anesthesiology, geriatric medicine, neurology, psychiatry and rehabilitation which presents a multidisciplinary management strategy. Over 60 chapters follow a standard, easy-to-read, quick access format on: clinical presentation, signs and symptoms, lab tests, imaging studies, differential diagnosis, pharmacotherapy, non-pharmacologic approach, interventional procedure, follow-up and prognosis. The broad spectrum of topics include headache, neck and back pain, bursitis, phantom limb pain, sickle cell disease and palliative care. Unlike other large, cumbersome texts currently available, this book serves as a quick, concise and pertinent reference in the diagnosis and management of common pain syndromes.
Download or read book Locomotor Training written by Susan J. Harkema and published by . This book was released on 2011 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical rehabilitation for walking recovery after spinal cord injury is undergoing a paradigm shift. Therapy historically has focused on compensation for sensorimotor deficits after SCI using wheelchairs and bracing to achieve mobility. With locomotor training, the aim is to promote recovery via activation of the neuromuscular system below the level of the lesion. What basic scientists have shown us as the potential of the nervous system for plasticity, to learn, even after injury is being translated into a rehabilitation strategy by taking advantage of the intrinsic biology of the central nervous system. While spinal cord injury from basic and clinical perspectives was the gateway for developing locomotor training, its application has been extended to other populations with neurologic dysfunction resulting in loss of walking or walking disability.
